Endocrinology (all articles)
Weight Gain in Rural Areas is the Main Driver of the Global Obesity Epidemic
10 May, 2019 | 04:58h | UTCRising rural body-mass index is the main driver of the global obesity epidemic in adults – Nature (free)
Commentaries: Rural Areas Drive Increases in Global Obesity – Scientific American (free) AND Obesity rising faster in rural areas than cities – Imperial College London (free)
Study: Fournier Gangrene Associated with SGLT2 Inhibitors
7 May, 2019 | 01:13h | UTCFournier Gangrene Associated With Sodium–Glucose Cotransporter-2 Inhibitors: A Review of Spontaneous Postmarketing Cases – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: SGLT2 inhibitors associated with rare, life-threatening necrotizing genital infections – ACP Internist (free) AND Potentiall fatal infection of genitals identified as rare side effect of SGLT2 Inhibitors – American College of Physicians (free) AND Postmarketing data support Fournier gangrene link with SGLT2 inhibitors – Medicine Matters (free)
Related: SGLT2 inhibitors: reports of Fournier’s gangrene (necrotising fasciitis of the genitalia or perineum) – GOV.UK (free)
Guideline Synopsis: Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum Period
7 May, 2019 | 01:06h | UTCDiagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum Period – JAMA (free for a limited period)
Original Article: 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum (free)
Aspirin for Primary Prevention: Is This the End of the Road?
6 May, 2019 | 22:43h | UTCAspirin for primary prevention: Is this the end of the Road? – Indian Heart Journal (free)
Related Randomized Trials: Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease (link to abstract and commentaries) AND Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes (free) AND Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly (free)
Related Meta-Analysis: Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events (link to abstract and commentaries) AND Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events (free)
Meta-analysis: Comparison of the Effects of GLP1 Receptor Agonists and SGLT2 Inhibitors for Prevention of Cardiovascular and Renal Outcomes in Type 2 Diabetes
6 May, 2019 | 22:27h | UTC
Study: Effects of Intensive Blood Pressure Therapy for Type 2 Diabetes
6 May, 2019 | 22:23h | UTCEffects of Blood Pressure Lowering on Clinical Outcomes According to Baseline Blood Pressure and Cardiovascular Risk in Patients With Type 2 Diabetes Mellitus: The ADVANCE Trial – Hypertension (link to abstract – $ for full-text)
Commentaries: Intensive blood pressure therapy for type 2 diabetes reduces cardiovascular risk – UPI (free) AND ADVANCE analysis fuels debate on BP targets in type 2 diabetes – Medwire News (free) AND Analysis Supports Aiming for Lower BP in Patients With Diabetes, Hypertension – TCTMD (free)
Review: Efficacy of Population‐wide Diabetes and Obesity Prevention Programs
5 May, 2019 | 21:51h | UTC
Related Commentary on Twitter
Posting again with a working link.
Our new paper – systematic review of population-level interventions for preventing T2 diabetes. (currently behind paywall but will be #openaccess after I've rattled their cage).https://t.co/QdUA8a5wQg— Trisha Greenhalgh #PeoplesVote (@trishgreenhalgh) May 1, 2019
Study: Predicting Individual Treatment Response in Diabetes
5 May, 2019 | 21:08h | UTCCommentaries: Predicting individual treatment response in diabetes – The Lancet Endocrinology & Diabetes (free) AND Simple clinical features can help personalise type 2 diabetes treatment – University of Exeter (free)
Related: Novel subgroups of adult-onset diabetes and their association with outcomes (link to abstract and commentaries)
WHO Study: Association between Characteristics at Birth, Breastfeeding and Obesity in 22 Countries
4 May, 2019 | 19:04h | UTCCommentary: Breastfeeding reduces child obesity risk by up to 25%, WHO finds – The Guardian (free)
GLP-1 Receptor Agonist Effective for Glucose Control in In Children and Adolescents with Type 2 Diabetes
4 May, 2019 | 16:45h | UTCLiraglutide in Children and Adolescents with Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Liraglutide Effective for Glucose Control in Adolescents with Diabetes – NEJM Journal Watch (free) AND Liraglutide Lowers A1C in Youth With Type 2 Diabetes, Phase 3 Study Finds – AJMC (free)
Study: Basal Insulin Doses >0.5 IU/kg/d Have Diminishing Additional Impact on Improving Glycemic Measures
2 May, 2019 | 12:53h | UTCCommentary: What’s the maximum effective basal insulin dose in T2D? – Univadis (free registration required)
Study: Benefits of Statins Questioned for Primary Prevention of Cardiovascular Disease
30 Apr, 2019 | 02:35h | UTCCommentary: NNT with statins is 400 for lower risk eligible patients, researchers estimate – Pulse (free)
Pediatric Obesity and Eating Disorders Symptoms: The Role of the Multidisciplinary Treatment
30 Apr, 2019 | 01:51h | UTC
Systematic Review: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention
26 Apr, 2019 | 02:05h | UTCSee also: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review – Agency for Healthcare Research and Quality (free) AND Full Report (free PDF) AND Evidence Summary (free PDF)
Cohort Study: Risk of Osteoporotic Fracture Similar with Denosumab vs. Alendronate
25 Apr, 2019 | 18:01h | UTCCommentary: No difference in fracture risk with denosumab vs alendronate – Medicine Matters (free)
Meta-Analysis: Effects of Intensive Blood Pressure Lowering in Patients with Type 2 Diabetes
25 Apr, 2019 | 02:02h | UTC
Study: Long-Term Weight Loss with Metformin
24 Apr, 2019 | 06:24h | UTCLong-Term Weight Loss with Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Metformin may help patients maintain weight loss long-term – American College of Physicians (free) AND Metformin may help people at high diabetes risk to maintain weight loss – Medicine Matters (free) AND Metformin may help patients maintain long-term weight loss – 2 Minute Medicine (free)
Clinical Update: Metformin in 2019
23 Apr, 2019 | 01:50h | UTCMetformin in 2019 – JAMA (free for a limited period)
Perspective: High-Fiber Diet Might Protect Against Range of Conditions
23 Apr, 2019 | 01:49h | UTCHigh-Fiber Diet Might Protect Against Range of Conditions – JAMA (free for a limited period)
Meta-Analysis of Randomized Trials: Comparative Outcomes of Heart Failure Among Existent Classes of Anti-diabetic Agents
22 Apr, 2019 | 22:25h | UTC
Clinical Management of Intermittent Fasting in Patients with Diabetes Mellitus
22 Apr, 2019 | 22:18h | UTCClinical Management of Intermittent Fasting in Patients with Diabetes Mellitus – Nutrients (free)
The authors acknowledge the almost non-existent evidence on this issue and suggest practical recommendations for the care of these patients.
Consensus Report: Nutrition Therapy for Adults With Diabetes or Prediabetes
22 Apr, 2019 | 02:22h | UTCNutrition Therapy for Adults With Diabetes or Prediabetes: A Consensus Report – Diabetes Care (free PDF)
Consensus on Postoperative Recommendations After Transsphenoidal Surgery
22 Apr, 2019 | 01:58h | UTC
Latest Updates on Lipid Management
21 Apr, 2019 | 21:14h | UTCLatest Updates on Lipid Management – High Blood Pressure & Cardiovascular Prevention (free)
Meta-analysis: Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes
20 Apr, 2019 | 16:07h | UTCCommentaries: Evidence Supporting Niacin Use for Cardiovascular Disease Prevention Evaluated – MPR (free) AND Niacin: Time to Revisit That FDA Indication – MedPage Today (free registration required)
Related Commentary on Twitter
Systematic review & meta-analysis shows #niacin may be useful in patients intolerant to #statins, but evidence may not be representative of current-day patients https://t.co/BIeGYYVbhw @PORTAL_Research @JAMACardio pic.twitter.com/LuHxTIalfe
— JAMA Network Open (@JAMANetworkOpen) April 16, 2019