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Endocrinology (all articles)

Cohort Study: Hypoglycemia at Hospital Discharge Linked to Poor Outcomes in Diabetics

19 May, 2019 | 14:42h | UTC

Association of glucose concentrations at hospital discharge with readmissions and mortality: A nationwide cohort study. – The Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)

Commentaries: Hypoglycemia at End of Hospital Stay Linked to Readmission, Mortality in Diabetes – Endocrinology Advisor (free) AND Hypoglycemia on the day of hospital discharge linked to adverse outcomes – Medicine Matters (free)

 


Study: Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults

17 May, 2019 | 06:52h | UTC

Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Early weight-loss surgery may improve type 2 diabetes, blood pressure outcomes – NIH/National Institute of Diabetes and Digestive and Kidney Diseases (free) AND Obesity surgery benefits may be bigger for teens than adults – Associated Press (free)

 


Randomized Trial: Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain

17 May, 2019 | 06:55h | UTC

Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake – Cell Metabolism (free for a limited period)

Commentaries: Controlled study links processed food to increased calorie consumption – Cell Press (free) AND NIH study finds heavily processed foods cause overeating and weight gain – NIH News Releases (free) AND Ultra-processed foods lead to higher calorie consumption and weight gain – Reuters (free) AND Expert reaction to study looking at processed food, calorie consumption and weight gain – Science Media Centre (free) AND Ultra-processed food causes weight gain – firm evidence at last – The Conversation (free)

 


BMJ Guideline: Treatment of Subclinical Hypothyroidism

16 May, 2019 | 05:26h | UTC

Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline – The BMJ (free)

Commentaries: Experts advise against hormone treatment in adults with mild thyroid problems – The BMJ (free) AND Experts: Don’t Treat Subclinical Hypothyroidism – NEJM Journal Watch (free)

Related: Meta-Analysis: Treating Subclinical Hypothyroidism is Not Associated with Quality of Life and Thyroid-Related Symptoms (link to abstract and commentaries) AND Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism (free study and commentary)

 

Related Commentary on Twitter

 


Study: Familial Hypercholesterolemia Among Young Adults with Myocardial Infarction

16 May, 2019 | 05:16h | UTC

Familial Hypercholesterolemia Among Young Adults With Myocardial Infarction – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Familial Hypercholesterolemia Seen in 10% of Young MI Patients – TCTMD (free) AND Familial Hypercholesterolemia Among Young Adults With MI – American College of Cardiology (free)

 


Obesity in the Critically Ill: A Narrative Review

14 May, 2019 | 06:05h | UTC

Obesity in the critically ill: a narrative review – Intensive Care Medicine (free)

Related Reviews: The Crashing Obese Patient – West Journal of Emergency Medicine (free) AND ARDS in Obese Patients: Specificities and Management – Critical Care (free)

Source: Critical Care Reviews Newsletter

 


Thyroid and Cardiovascular Disease Research Agenda for Enhancing Knowledge, Prevention, and Treatment

14 May, 2019 | 05:35h | UTC

Thyroid and Cardiovascular Disease Research Agenda for Enhancing Knowledge, Prevention, and Treatment – Circulation (free PDF) (via @paomorejon see Tweet)

Commentary: New recommendations for a thyroid and cardiovascular disease research agenda – Mary Ann Liebert, Inc (free)

 


Meta-Analysis: Frequency of Intracranial Hemorrhage with Low-Dose Aspirin in Individuals Without Symptomatic Cardiovascular Disease

14 May, 2019 | 05:23h | UTC

Frequency of Intracranial Hemorrhage With Low-Dose Aspirin in Individuals Without Symptomatic Cardiovascular Disease: A Systematic Review and Meta-analysis – JAMA Neurology (free for a limited period)

Commentaries: Low-dose aspirin linked to bleeding in the skull, new report says – CNN (free) AND Study links low-dose aspirin to bleeding inside the skull – UPI (free)

 

Related Commentary on Twitter

 


Cohort Study: High Intakes of Vitamins B6 and B12 From Food and Supplements are Associated with Increased Risk of Hip Fracture

13 May, 2019 | 01:25h | UTC

Association of High Intakes of Vitamins B6 and B12 From Food and Supplements with Risk of Hip Fracture Among Postmenopausal Women in the Nurses’ Health Study – JAMA Network Open (free)

 


Systematic Review: Impact of Whole, Fresh Fruit Consumption on Energy Intake and Adiposity

12 May, 2019 | 21:44h | UTC

Impact of Whole, Fresh Fruit Consumption on Energy Intake and Adiposity: A Systematic Review – Frontiers in Nutrition (free)

 


Diabetes Treatments and Their Perioperative Implications

11 May, 2019 | 15:47h | UTC

Recent advances in diabetes treatments and their perioperative implications – Current Opinion in Anesthesiology (free)

Source: Critical Care Reviews Newsletter

“Sulfonylureas and SGLT2i should be ceased before moderate or major surgery. Other oral antihyperglycemic therapies may be continued or ceased.

 


Study: Late-onset Type 1 Diabetes Commonly Treated as Type 2 Diabetes

10 May, 2019 | 05:03h | UTC

Type 1 diabetes defined by severe insulin deficiency occurs after 30 years of age and is commonly treated as type 2 diabetes – Diabetologia (free)

Commentary: Patients with late-onset type 1 diabetes commonly treated as having type 2 diabetes – ACP Diabetes (free)

 


Weight Gain in Rural Areas is the Main Driver of the Global Obesity Epidemic

10 May, 2019 | 04:58h | UTC

Rising rural body-mass index is the main driver of the global obesity epidemic in adults – Nature (free)

Commentaries: Rural Areas Drive Increases in Global Obesity – Scientific American (free) AND Obesity rising faster in rural areas than cities – Imperial College London (free)

 


Study: Fournier Gangrene Associated with SGLT2 Inhibitors

7 May, 2019 | 01:13h | UTC

Fournier Gangrene Associated With Sodium–Glucose Cotransporter-2 Inhibitors: A Review of Spontaneous Postmarketing Cases – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: SGLT2 inhibitors associated with rare, life-threatening necrotizing genital infections – ACP Internist (free) AND Potentiall fatal infection of genitals identified as rare side effect of SGLT2 Inhibitors – American College of Physicians (free) AND Postmarketing data support Fournier gangrene link with SGLT2 inhibitors – Medicine Matters (free)

Related: SGLT2 inhibitors: reports of Fournier’s gangrene (necrotising fasciitis of the genitalia or perineum) – GOV.UK (free)

 


Guideline Synopsis: Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum Period

7 May, 2019 | 01:06h | UTC

Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum Period – JAMA (free for a limited period)

Original Article: 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum (free)

 


Aspirin for Primary Prevention: Is This the End of the Road?

6 May, 2019 | 22:43h | UTC

Aspirin for primary prevention: Is this the end of the Road? – Indian Heart Journal (free)

Related Randomized Trials: Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease (link to abstract and commentaries) AND Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes (free) AND Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly (free)

Related Meta-Analysis: Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events (link to abstract and commentaries) AND Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events (free)

 


Meta-analysis: Comparison of the Effects of GLP1 Receptor Agonists and SGLT2 Inhibitors for Prevention of Cardiovascular and Renal Outcomes in Type 2 Diabetes

6 May, 2019 | 22:27h | UTC

Comparison of the Effects of Glucagon-Like Peptide Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors for Prevention of Major Adverse Cardiovascular and Renal Outcomes in Type 2 Diabetes Mellitus: Systematic Review and Meta-Analysis of Cardiovascular Outcomes Trials – Circulation (free)

 


Study: Effects of Intensive Blood Pressure Therapy for Type 2 Diabetes

6 May, 2019 | 22:23h | UTC

Effects of Blood Pressure Lowering on Clinical Outcomes According to Baseline Blood Pressure and Cardiovascular Risk in Patients With Type 2 Diabetes Mellitus: The ADVANCE Trial – Hypertension (link to abstract – $ for full-text)

Commentaries: Intensive blood pressure therapy for type 2 diabetes reduces cardiovascular risk – UPI (free) AND ADVANCE analysis fuels debate on BP targets in type 2 diabetes – Medwire News (free) AND Analysis Supports Aiming for Lower BP in Patients With Diabetes, Hypertension – TCTMD (free)

 


Review: Efficacy of Population‐wide Diabetes and Obesity Prevention Programs

5 May, 2019 | 21:51h | UTC

Efficacy of population‐wide diabetes and obesity prevention programs: An overview of systematic reviews on proximal, intermediate, and distal outcomes and a meta‐analysis of impact on BMI – Obesity Reviews (free)

 

Related Commentary on Twitter

 


Study: Predicting Individual Treatment Response in Diabetes

5 May, 2019 | 21:08h | UTC

Disease progression and treatment response in data-driven subgroups of type 2 diabetes compared with models based on simple clinical features: an analysis using clinical trial data – The Lancet Endocrinology & Diabetes (free)

Commentaries: Predicting individual treatment response in diabetes – The Lancet Endocrinology & Diabetes (free) AND Simple clinical features can help personalise type 2 diabetes treatment – University of Exeter (free)

Related: Novel subgroups of adult-onset diabetes and their association with outcomes (link to abstract and commentaries)

 


WHO Study: Association between Characteristics at Birth, Breastfeeding and Obesity in 22 Countries

4 May, 2019 | 19:04h | UTC

Association between Characteristics at Birth, Breastfeeding and Obesity in 22 Countries: The WHO European Childhood Obesity Surveillance Initiative – Obesity Facts (free)

Commentary: Breastfeeding reduces child obesity risk by up to 25%, WHO finds – The Guardian (free)

 


GLP-1 Receptor Agonist Effective for Glucose Control in In Children and Adolescents with Type 2 Diabetes

4 May, 2019 | 16:45h | UTC

Liraglutide in Children and Adolescents with Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Liraglutide Effective for Glucose Control in Adolescents with Diabetes – NEJM Journal Watch (free) AND Liraglutide Lowers A1C in Youth With Type 2 Diabetes, Phase 3 Study Finds – AJMC (free)

 


Study: Basal Insulin Doses >0.5 IU/kg/d Have Diminishing Additional Impact on Improving Glycemic Measures

2 May, 2019 | 12:53h | UTC

When Basal Insulin is Not Enough: A Dose Response Relationship Between Insulin Glargine 100 Units/mL (U100) and Glycemic Control – Diabetes, Obesity and Metabolism (free)

Commentary: What’s the maximum effective basal insulin dose in T2D? – Univadis (free registration required)

 


Study: Benefits of Statins Questioned for Primary Prevention of Cardiovascular Disease

30 Apr, 2019 | 02:35h | UTC

Statins for the primary prevention of cardiovascular disease: an overview of systematic reviews – BMJ Open (free)

Commentary: NNT with statins is 400 for lower risk eligible patients, researchers estimate – Pulse (free)

 


Pediatric Obesity and Eating Disorders Symptoms: The Role of the Multidisciplinary Treatment

30 Apr, 2019 | 01:51h | UTC

Pediatric Obesity and Eating Disorders Symptoms: The Role of the Multidisciplinary Treatment. A Systematic Review – Frontiers in Pediatrics (free)

 


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