Endocrinology (all articles)
#ESCCongress – [Abstract Only] Randomized Trial: No Overall Benefit from Ticagrelor added to Aspirin in Patients with Stable Coronary Disease and Diabetes
2 Sep, 2019 | 00:56h | UTCTicagrelor in Patients with Stable Coronary Disease and Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
Related Study: Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention (THEMIS-PCI): a phase 3, placebo-controlled, randomised trial – The Lancet (free registration required)
Commentaries: THEMIS: No overall benefit of ticagrelor in people with diabetes, coronary artery disease – Medicine Matters (free) AND THEMIS, THEMIS-PCI Assess Benefits of Ticagrelor Plus Aspirin in Patients With Stable CAD and Diabetes, History of PCI – American College of Cardiology (free)
Related Commentary on Twitter
https://twitter.com/megnahprakash/status/1168196208847798273
Cohort Study: SGLT2 Inhibitors Associated with Reduced Risk of Heart Failure
30 Aug, 2019 | 08:24h | UTCCommentaries: SGLT2 inhibitors cut heart failure risk for T2D patients – Cardiovascular Business (free) AND Newer diabetes drug drops heart failure risk by 34 percent, study says – UPI (free)
Related observational studies: SGLT2 agents may reduce cardiovascular risk in diabetics (link to abstract and commentaries)
NICE Guideline: Management of Type 2 Diabetes in Adults
29 Aug, 2019 | 06:56h | UTCType 2 diabetes in adults: management – National Institute for Health and Care Excellence (free)
Related Guideline: ADA 2019 Standards of Medical Care in Diabetes (free supplement)
Meta-Analysis: Estrogen-Based Hormone Therapy Does Not Improve Muscle Mass in Postmenopausal Women
29 Aug, 2019 | 06:08h | UTCCommentary: Hormone Therapy Doesn’t Prevent Age-Related Muscle Loss in Women – Medscape (free registration required)
Alternate Day Fasting Improves Physiological and Molecular Markers is Small Study
29 Aug, 2019 | 06:00h | UTCAlternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans – Cell Metabolism (free for a limited period)
Commentaries: Alternate-day fasting associated with weight loss – Reuters (free) AND Clinical trial shows alternate-day fasting a safe alternative to caloric restriction – Cell Press (free) AND Alternate-Day Fasting in Short Term Safe, Has Metabolic Benefits – Medscape (free registration required)
Randomized Trial: High-Dose Vitamin D Supplementation Does Not Improve Bone Health and May Result in Lower Bone Mineral Density
28 Aug, 2019 | 02:33h | UTCEffect of High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: High-Dose Vitamin D Might Reduce Bone Mineral Density – NEJM Journal Watch (free)
Related Commentary on Twitter
Vitamin D study: "Among healthy adults, supplementation with higher doses of vitamin D did not improve bone health." https://t.co/pugZ4Ilxke via @JAMA_current @SMCCanada cc @DietitiansCAN @medmyths @joansalgeblake @picardonhealth @CBCHealth pic.twitter.com/4BocJC1EeT
— Timothy Caulfield (@CaulfieldTim) August 27, 2019
Guidelines on the Management of Thyroid Dysfunction following Immune Reconstitution Therapy
28 Aug, 2019 | 02:13h | UTC
Podcast: Diabetes Update
27 Aug, 2019 | 01:54h | UTC#168 Diabetes Update with Jeff Colburn MD – The Curbsiders Internal Medicine Podcast (free audio and summary)
Cohort Study: Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality
27 Aug, 2019 | 01:49h | UTCAssociation of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality – JAMA Internal Medicine (free for a limited period)
Commentary: More plant protein tied to longer life – Reuters (free)
Related Studies: Plant‐Based Diets Are Associated with a Lower Risk of Cardiovascular Disease and All‐Cause Mortality (free) AND Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease (link to abstract and commentaries) AND Cohort Study: Fruit, vegetable, and legume intake, and cardiovascular disease and deaths (link to abstract and commentaries)
Study: Acute Gallbladder or Biliary Disease More Common in Patients Using Liraglutide
27 Aug, 2019 | 00:31h | UTCEffects of Liraglutide Compared With Placebo on Events of Acute Gallbladder or Biliary Disease in Patients With Type 2 Diabetes at High Risk for Cardiovascular Events in the LEADER Randomized Trial – Diabetes Care (free PDF for a limited period)
Commentary: Gallbladder, Biliary Tract Events Increased With Liraglutide – Medscape (free registration required)
Continuous Glucose Monitoring Sensors for Diabetes Management: A Review of Technologies and Applications
27 Aug, 2019 | 00:12h | UTCRelated: Diabetes Technology: Review of the 2019 American Diabetes Association Standards of Medical Care in Diabetes – Annals of Internal Medicine (free)
Postoperative Management in Patients with Pheochromocytoma and Paraganglioma
27 Aug, 2019 | 00:13h | UTCPostoperative Management in Patients with Pheochromocytoma and Paraganglioma – Cancers (free)
Related Reviews: Current perioperative management of pheochromocytomas – Indian Journal of Urology (free) AND Surgical and Pharmacological Management of Functioning Pheochromocytoma and Paraganglioma – Paraganglioma: A Multidisciplinary Approach (free)
Meta-Analysis: Quality of Dietary Fat and Genetic Risk of Type 2 Diabetes
25 Aug, 2019 | 21:07h | UTCCommentaries: Interventions for type 2 diabetes successful across the genetic landscape – Massachusetts General Hospital (free) AND Genetics no barrier to dietary modification benefits on type 2 diabetes risk – medwire News (free)
Optimal Management of Diabetic Foot Osteomyelitis
25 Aug, 2019 | 13:35h | UTCRelated: 2012 Infectious Diseases Society of America Clinical Practice Guideline for the Diagnosis and Treatment of Diabetic Foot Infections (free) AND Osteomyelitis in diabetic foot: A comprehensive overview – World Journal of Diabetes (free) AND Osteomyelitis in the diabetic foot – Diabetic Foot and Ankle (free) AND Diabetic foot – The BMJ (free) AND Diagnosis and Management of Diabetic Foot Complications – American Diabetes Association (free)
[Abstract Only] Randomized Trial: Effectiveness of Polypill for Primary and Secondary Prevention of Cardiovascular Diseases
23 Aug, 2019 | 08:48h | UTCEffectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial – The Lancet (link to abstract – $ for full-text)
Commentaries: 4-Drug Polypill Cuts CV Risk – NEJM Journal Watch (free) AND Four-in-one pill prevents third of heart problems – BBC (free)
Related: Clinical Impact of the Polypill for Cardiovascular Prevention in Latin America: A Consensus Statement of the Inter-American Society of Cardiology – Global Heart (free) AND Perspective: The Polypill and the Long Journey to Major Impact (opinion and reviews on the subject) AND Research: Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care (free commentaries)
Related Commentary on Twitter
NEW Research—Large five-year randomised trial supports use of #polypill to prevent #CVD: finding from PolyIran, a pragmatic, cluster-randomised trial #LancetCardiology #ESCCongress https://t.co/YtU4MBPWom pic.twitter.com/GocADDE7Kv
— The Lancet (@TheLancet) August 23, 2019
Systematic Review: Management of Glucose Control in Noncritically Ill, Hospitalized Patients Receiving Parenteral and/or Enteral Nutrition
23 Aug, 2019 | 08:34h | UTCRelated Guidelines: Diabetes Care in the Hospital: Standards of Medical Care in Diabetes—2019 – American Diabetes Association (free) AND In-Hospital Management of Diabetes – Diabetes Canada Clinical Practice Guidelines Expert Committee (free)
Related Reviews: Glucose Management in Hospitalized Patients – American Family Physician (free) AND Update on Glucose Management Among Noncritically Ill Patients Hospitalized on Medical and Surgical Wards – Journal of the Endocrine Society (free)
Perspective: The Keto Diet Is Popular, but Is It Good for You?
22 Aug, 2019 | 10:56h | UTCThe Keto Diet Is Popular, but Is It Good for You? – The New York Times (10 articles per month are free)
Related Consensus Statement: Very-low-calorie ketogenic diet (VLCKD) in the management of metabolic diseases: systematic review and consensus statement from the Italian Society of Endocrinology (SIE) – Journal of Endocrinological Investigation (free)
Meta-analysis: Omega-3 Fats Not Beneficial for Diabetes Prevention or Treatment
22 Aug, 2019 | 10:53h | UTCCommentaries: The role of nutrition in disease prevention—how we can find better answers? – The BMJ Opinion (free) AND Omega-3 fats have little or no effect on type 2 diabetes – BMJ (free) AND Lack of omega-3 effect on type 2 diabetes confirmed – Medicine Matters (free) AND Fish oil pills ‘no benefit’ for type 2 diabetes – BBC (free)
Related Randomized Trial: Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus (free study and commentaries)
Meta-analysis: Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth
21 Aug, 2019 | 08:38h | UTCAssociation of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Editorial: Thyroid Function Test Abnormalities During Pregnancy (free)
AHA Scientific Advisory: Omega-3 Fatty Acids for the Management of Hypertriglyceridemia
20 Aug, 2019 | 08:57h | UTCNews Release: Prescription omega-3 fatty acid medications effectively lower high triglycerides – American Heart Association (free)
Related: Omega-3 Supplements Do Not Reduce the Risk of Cancer or Cardiovascular Disease (randomized trial and systematic reviews on the subject)
Consensus Recommendations: Pregnancy After Bariatric Surgery
18 Aug, 2019 | 22:08h | UTCRelated: Pregnancy after bariatric surgery and adverse perinatal outcomes: A systematic review and meta-analysis – PLOS Medicine (free)
Position Statement: Hormonal Management of Adult Transgender and Gender Diverse Individuals
18 Aug, 2019 | 21:28h | UTCRelated Guidelines: Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free) AND Policy Statement: Care and Support for Transgender and Gender-Diverse Children and Adolescents (free statement and commentaries)
Meta-Analysis: Association Between Vitamin D Supplementation and Mortality
16 Aug, 2019 | 07:59h | UTCRelated: Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention (link to abstract and commentary) AND NICE Guideline: Vitamin D Supplementation (free)
Vitamin D supplementation was not associated with all-cause mortality, cardiovascular mortality, or non-cancer, non-cardiovascular mortality. However, Vitamin D supplementation statistically significantly reduced the risk of cancer death by 16%.
Related Commentary on Twitter
Vitamin D supplementation alone was not associated with all cause mortality in adults compared with placebo or no treatment. However, it was associated with a reduced risk of cancer mortality by 16%, finds #BMJResearch https://t.co/jc4Tdxl6Bb
— The BMJ (@bmj_latest) August 12, 2019
[Abstract Only] Study: Diabetes Being Overtreated in Many Vulnerable Clinically Complex Adults
16 Aug, 2019 | 07:50h | UTCSevere Hypoglycemia Attributable to Intensive Glucose-Lowering Therapy Among US Adults With Diabetes – Mayo Clinic Proceedings (link to abstract – $ for full-text)
Commentary: Too Much of a Good Thing Can Be Dangerous, Finds Researchers Investigating Hypoglycemia – Mayo Clinic (free)
Related Studies: Overtreatment and Deintensification of Diabetic Therapy among Medicare Beneficiaries – Journal of General Internal Medicine (free) AND Rates of Deintensification of Blood Pressure and Glycemic Medication Treatment Based on Levels of Control and Life Expectancy in Older Patients With Diabetes Mellitus – JAMA Internal Medicine (free)
ADA Guideline Synopsis: Diabetes Technology
13 Aug, 2019 | 08:00h | UTCOriginal Guideline: ADA 2019 Standards of Medical Care in Diabetes (free)