Endocrinology (all articles)
Randomized Trial: No Difference in Major Cardiovascular Outcomes in Patients with Type 2 Diabetes Treated with DPP-4 Inhibitor vs. Sulfonylurea
20 Sep, 2019 | 08:15h | UTCEffect of Linagliptin vs Glimepiride on Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes: The CAROLINA Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Sulfonylureas and Cardiovascular Safety: The Final Verdict? – JAMA (free for a limited period)
Commentary: CAROLINA: No Added Heart Risk With Sulfonylureas – MedPage Today (free registration required)
Cohort Study: Metformin Linked to Reduced Risk of Cardiovascular Events Compared to Sulfonylurea Among Patients with Diabetes and Reduced Kidney Function
20 Sep, 2019 | 08:19h | UTCAssociation of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function – JAMA (free for a limited period)
Commentaries: Metformin Superior for Lowering CV Risk in Diabetics Who Progress to CKD – Renal & Urology News (free) AND Metformin Monotherapy Benefits Heart Even in Early CKD – MedPage Today (free registration required)
Related Commentary on Twitter
Monotherapy treatment with #metformin, compared with a #sulfonylurea, was associated with a lower risk of MACE among patients with diabetes and reduced kidney function https://t.co/Z1EZAjOOET
— JAMA (@JAMA_current) September 19, 2019
Consensus Statement: Healthy Beverage Consumption in Early Childhood: Recommendations from Key Health and Nutrition Organizations
19 Sep, 2019 | 10:28h | UTCConsensus Statement: Healthy Beverage Consumption in Early Childhood: Recommendations from Key National Health and Nutrition Organizations – Health Eating Research (free PDF)
News Releases: 4 groups issue consensus report on healthy beverages for 0- to 5-year-olds – American Academy of Pediatrics (free) AND Leading Health Organizations Support First-Ever Consensus Recommendations to Encourage Young Children’s Consumption of Healthy Drinks – American Heart Association (free)
Commentaries: What Should Young Children Drink? Mostly Milk and Water, Scientists Say – The New York Times (10 articles per month are free) AND Parents Should Limit Kids’ Juice Consumption, Guidelines Say – U.S. News (free)
See also: Health Kids, Health Drinks (free resources for the public)
Related: AAP/AHA Policy Statement: Public Policies to Reduce Sugary Drink Consumption in Children and Adolescents (free)
[Abstract Only] Randomized Trial: GLP-1 Receptor Agonist Superior to SGLT2 Inhibitor for Glucose Control and Weight Loss in Patients with Type 2 Diabetes Uncontrolled on Metformin Therapy
19 Sep, 2019 | 07:51h | UTCEfficacy and safety of once-weekly semaglutide versus daily canagliflozin as add-on to metformin in patients with type 2 diabetes (SUSTAIN 8): a double-blind, phase 3b, randomised controlled trial – The Lancet Endocrinology & Metabolism (link to abstract – $ for full-text)
Commentary: Add-On Diabetes Treatment: Semaglutide Improves HbA1c Better Than Canagliflozin – NEJM Journal Watch (free)
[Abstract Only] Randomized Trial: Early Combination Therapy Provides Greater and Durable Long-term Glucose Control in Patients with Newly Diagnosed Type 2 Diabetes
19 Sep, 2019 | 07:49h | UTCGlycaemic durability of an early combination therapy with vildagliptin and metformin versus sequential metformin monotherapy in newly diagnosed type 2 diabetes (VERIFY): a 5-year, multicentre, randomised, double-blind trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Two-drug combo more effective at lowering blood sugar in diabetes patients – UPI (free) AND New study shows long-term durability of early combination therapy in patients newly diagnosed with type 2 diabetes – MedicalXpress (free)
[Abstract Only] Study: Benefits and Harms of Aspirin for Primary Prevention of Cardiovascular Disease
18 Sep, 2019 | 08:36h | UTCPersonalized Prediction of Cardiovascular Benefits and Bleeding Harms From Aspirin for Primary Prevention: A Benefit–Harm Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Aspirin may benefit some people without cardiovascular disease, new analysis finds – ACP Internist (free) AND Some Adults Without Heart Disease May Benefit From Aspirin – MedicalResearch.com (free) AND Expert reaction to study looking at benefits and harms of aspirin in people without cardiovascular disease – Science Media Centre (free)
[Abstract Only] Meta-Analysis: Cardiovascular, Mortality, and Kidney Outcomes with GLP-1 Receptor Agonists in Patients with Type 2 Diabetes
18 Sep, 2019 | 01:34h | UTCCardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentary: GLP-1 RA Benefits Extend Beyond MACE Reduction – MedPage Today (free registration required)
Source: EvidenceAlerts
Scientific Statement: Review of Current Evidence and Clinical Recommendations on the Effects of Low-carbohydrate and Very-low-carbohydrate (Including Ketogenic) Diets for the Management of Body Weight and Other Cardiometabolic Risk Factors
17 Sep, 2019 | 07:25h | UTC
Cohort Study: Lower Carbohydrate Diets and All-cause and Cause-specific Mortality
17 Sep, 2019 | 07:19h | UTCCommentary: Lower Carbohydrate Diets, All-Cause and Cause-Specific Mortality – American College of Cardiology (free)
Review: Association Between Antipsychotic Medication Use and Diabetes
17 Sep, 2019 | 01:01h | UTCAssociation Between Antipsychotic Medication Use and Diabetes – Current Diabetes Reports (free)
Meta-analysis: Combined Lifestyle Factors and Risk of Incident Type 2 Diabetes and Prognosis Among Individuals with Type 2 Diabetes
13 Sep, 2019 | 08:16h | UTCCommentary: Diabetes Risk Plummets by 75% When Multiple Risk Factors Tackled – Medscape (free registration required)
Polycystic Ovary Syndrome and Cardiometabolic Risk: Opportunities for Cardiovascular Disease Prevention
10 Sep, 2019 | 23:58h | UTC
Randomized Trial: Effectiveness of Gamification Interventions for Increasing Physical Activity Among Overweight and Obese Adults
10 Sep, 2019 | 01:49h | UTCEffectiveness of Behaviorally Designed Gamification Interventions With Social Incentives for Increasing Physical Activity Among Overweight and Obese Adults Across the United States: The STEP UP Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
Commentaries: Using a wearable device to exercise more? Add competition to improve results – University of Pennsylvania (free) AND Tracking your exercise more effective with competition, study says – CNN (free)
Guidelines for Childbearing Female Candidates for Bariatric Surgery, Pregnancy, and Post-partum Management After Bariatric Surgery
10 Sep, 2019 | 01:44h | UTCRelated: Pregnancy after bariatric surgery: Consensus recommendations for periconception, antenatal and postnatal care – Obesity Reviews (free) AND Fertility, Pregnancy and Lactation After Bariatric Surgery – a Consensus Statement from the OEGGG – Geburtshilfe und Frauenheilkunde (free) AND Pregnancy after bariatric surgery and adverse perinatal outcomes: A systematic review and meta-analysis – PLOS Medicine (free) AND Nutrition in Pregnancy Following Bariatric Surgery – Nutrients (free) AND Pregnancy after bariatric surgery: a narrative literature review and discussion of impact on pregnancy management and outcome – BMC Pregnancy and Childbirth (free)
[Abstract Only] Meta-analysis: SGLT2 Inhibitors Beneficial for the Prevention of Kidney Failure in Patients with Type 2 Diabetes
10 Sep, 2019 | 01:14h | UTCSGLT2 inhibitors for the prevention of kidney failure in patients with type 2 diabetes: a systematic review and meta-analysis – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: Meta-analysis supports use of SGLT2 inhibitors to prevent kidney failure – Medicine Matters (free) AND New study confirms protective effect of diabetes drugs against kidney failure – George Institute for Global Health (free)
Polycystic Ovary Syndrome: Pathophysiology, Presentation, and Treatment With Emphasis on Adolescent Girls
10 Sep, 2019 | 01:08h | UTCRelated: Recent Advances in the Understanding and Management of Polycystic Ovary Syndrome (free review and guidelines)
Study: Variation of All-cause and Cause-specific Mortality with BMI in One Million Parent-son Pairs
10 Sep, 2019 | 00:58h | UTC
Systematic Review: Low‐carbohydrate Diets for Type 2 Diabetes Management
9 Sep, 2019 | 00:05h | UTCSource: EvidenceAlerts
Global Consensus Position Statement on the Use of Testosterone Therapy for Women
8 Sep, 2019 | 23:56h | UTCCommentary: Coalition issues international consensus on testosterone treatment for women – The Endocrine Society (free)
Observational Study Suggests HbA1c levels of 6.5-7.0% May be Optimal for Individuals with Type 1 Diabetes
6 Sep, 2019 | 08:55h | UTCCommentaries: Microvascular benefits of lowest HbA1c target in type 1 diabetes questioned – Medwire News (free) AND How blood sugar levels affect risks in type 1 diabetes – University of Gothenburg (free) AND HbA1c levels of 6.5-7.0 percent may be optimal for adults and children with T1D – Univadis (free registration required)
#ESCCongress – Observational Study Finds Metabolic Surgery May Reduce the Risk of Death and Cardiovascular Complications in Diabetic Patients
3 Sep, 2019 | 01:22h | UTCAssociation of Metabolic Surgery With Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes and Obesity – JAMA (free for a limited period)
Editorial: The Role of Bariatric Surgery in Managing the Macrovascular Complications of Obesity-Related Type 2 Diabetes (free for a limited period)
Commentaries: Weight-Loss Surgery Associated with 40% Reduction in Risk of Death and Heart Complications in Patients with Diabetes and Obesity, Study Shows – Cleveland Clinic (free) AND Fewer cardiovascular events seen in diabetics after weight-loss surgery – Reuters (free) AND Metabolic Surgery Improves CV Outcomes in Patients With Diabetes, Obesity – American College of Cardiology (free) AND Weight-Loss Surgery May Reduce Heart Risks in People With Type 2 Diabetes – The New York Times (10 articles per month are free)
Related Studies: Observational Study Links Bariatric Surgery to Lower Mortality but Higher Risk of Adverse Events (link to abstract) AND Association of Bariatric Surgery vs Usual Care Obesity Management With All-Cause Mortality (free study and commentaries)
#ESCCongress – 2019 ESC/EAS Guidelines for the Management of Dyslipidaemias
2 Sep, 2019 | 01:15h | UTC
Related Commentary on Twitter
JUST RELEASED: 2019 #ESCGuidelines for the management of Dyslipidaemias – what's new? what has changed? what are the main 2019 recommendations? https://t.co/aBU1PkGc2k
@escardio #ESCCongress #ESCCoT #cardiotwitter pic.twitter.com/NChfhPNXDq
— European Society of Cardiology (@escardio) August 31, 2019
#ESCCongress – 2019 ESC Guidelines on Diabetes, Pre-diabetes, and Cardiovascular Diseases
2 Sep, 2019 | 01:14h | UTC
Related Commentary on Twitter
JUST RELEASED: 2019 #ESGuidelines on Diabetes, Pre-Diabetes and Cardiovascular Diseases – what's new? what has changed? what are the main 2019 recommendations? https://t.co/FY6xt34jNo#ESCCongress #cardiotwitter pic.twitter.com/q1HBPfRO5f
— European Society of Cardiology (@escardio) August 31, 2019
#ESCCongress – [Not Published Yet] Randomized Trial: SGLT2 inhibitors Seems Beneficial for Heart Failure Even in Nondiabetics
2 Sep, 2019 | 01:09h | UTCCommentaries: Dapagliflozin in Patients With Heart Failure and Reduced Ejection Fraction – DAPA-HF – American College of Cardiology (free) Dapagliflozin reduces death and hospitalisation in patients with heart failure – European Society of Cardiology (free)
Related Commentary on Twitter
DAPA-HF trial at #ESCCongress: significant reduction of events in HFrEF patients by dapagliflozine. Half of the 5744 pts had diabetes, the others did not: same effect in both groups.
SGLT2 inhibitors just better diuretics or the "statins of HF"?@escardio #cardiotwitter pic.twitter.com/nzTv58d0cd— Stephan Achenbach (@Steph_Achenbach) September 1, 2019
Meta-Analysis: Menopausal Hormone Therapy Increases Breast Cancer Risk
30 Aug, 2019 | 08:55h | UTCCommentaries: Menopausal hormones: definitive evidence for breast cancer – The Lancet (free) AND Menopausal hormone therapy and 20-year breast cancer mortality – The Lancet (free) AND Hormone therapy during menopause raises breast cancer risk for years, study finds – STAT (free) AND Expert reaction to study looking at HRT use and risk of breast cancer – Science Media Centre (free)