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Endocrinology (all articles)

Meta-analysis: Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth

21 Aug, 2019 | 08:38h | UTC

Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis – JAMA (free for a limited period)

Editorial: Thyroid Function Test Abnormalities During Pregnancy (free)

 


AHA Scientific Advisory: Omega-3 Fatty Acids for the Management of Hypertriglyceridemia

20 Aug, 2019 | 08:57h | UTC

Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association – Circulation (free PDF)

News Release: Prescription omega-3 fatty acid medications effectively lower high triglycerides – American Heart Association (free)

Related: Omega-3 Supplements Do Not Reduce the Risk of Cancer or Cardiovascular Disease (randomized trial and systematic reviews on the subject)

 


Consensus Recommendations: Pregnancy After Bariatric Surgery

18 Aug, 2019 | 22:08h | UTC

Pregnancy after bariatric surgery: Consensus recommendations for periconception, antenatal and postnatal care – Obesity Reviews (free)

Related: Pregnancy after bariatric surgery and adverse perinatal outcomes: A systematic review and meta-analysis – PLOS Medicine (free)

 


Position Statement: Hormonal Management of Adult Transgender and Gender Diverse Individuals

18 Aug, 2019 | 21:28h | UTC

Position statement on the hormonal management of adult transgender and gender diverse individuals – The Medical Journal of Australia (free)

Related Guidelines: Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free) AND Policy Statement: Care and Support for Transgender and Gender-Diverse Children and Adolescents (free statement and commentaries)

 


Meta-Analysis: Association Between Vitamin D Supplementation and Mortality

16 Aug, 2019 | 07:59h | UTC

Association between vitamin D supplementation and mortality: systematic review and meta-analysis – The BMJ (free)

Related: Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention (link to abstract and commentary) AND NICE Guideline: Vitamin D Supplementation (free)

Vitamin D supplementation was not associated with all-cause mortality, cardiovascular mortality, or non-cancer, non-cardiovascular mortality. However, Vitamin D supplementation statistically significantly reduced the risk of cancer death by 16%.

 

Related Commentary on Twitter

 


[Abstract Only] Study: Diabetes Being Overtreated in Many Vulnerable Clinically Complex Adults

16 Aug, 2019 | 07:50h | UTC

Severe Hypoglycemia Attributable to Intensive Glucose-Lowering Therapy Among US Adults With Diabetes – Mayo Clinic Proceedings (link to abstract – $ for full-text)

Commentary: Too Much of a Good Thing Can Be Dangerous, Finds Researchers Investigating Hypoglycemia – Mayo Clinic (free)

Related Studies: Overtreatment and Deintensification of Diabetic Therapy among Medicare Beneficiaries – Journal of General Internal Medicine (free)  AND Rates of Deintensification of Blood Pressure and Glycemic Medication Treatment Based on Levels of Control and Life Expectancy in Older Patients With Diabetes Mellitus – JAMA Internal Medicine (free)

 


ADA Guideline Synopsis: Diabetes Technology

13 Aug, 2019 | 08:00h | UTC

Diabetes Technology: Review of the 2019 American Diabetes Association Standards of Medical Care in Diabetes – Annals of Internal Medicine (free)

Original Guideline: ADA 2019 Standards of Medical Care in Diabetes (free)

 


[Abstract Only] Observational Study Links Bariatric Surgery to Lower Mortality but Higher Risk of Adverse Events

13 Aug, 2019 | 05:51h | UTC

Long-term adverse events after sleeve gastrectomy or gastric bypass: a 7-year nationwide, observational, population-based, cohort study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Commentary: Death Risk Drops After Bariatric Surgery in Obese Patients – MedPage Today (free registration required)

Related Research: Association of Bariatric Surgery vs Usual Care Obesity Management With All-Cause Mortality (free study and commentaries)

 

Related Commentary on Twitter

 


[Abstract Only] Diabetes Subgroups Have Different Risk of Diabetes-associated Diseases

13 Aug, 2019 | 05:53h | UTC

Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study – The Lancet Diabetes & Endocrinology (link to abstract and commentaries)

Commentaries: Different diabetes phenotypes associated with varying prevalence of complications – ACP Diabetes (free) AND Cluster analysis may help to predict diabetic complications – medwire News (free)

Related Study: Novel subgroups of adult-onset diabetes and their association with outcomes (link to abstract and commentaries)

 

Related Commentary on Twitter

 


Meta-Analysis: Medications that Reduce or Increase the Risk of New Onset Diabetes

11 Aug, 2019 | 22:24h | UTC

Medications Affecting the Biochemical Conversion to Type 2 Diabetes: A Systematic Review and Meta-Analysis – The Journal of Clinical Endocrinology & Metabolism (free)

α-Glucosidase inhibitors, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, metformin, orlistat, phentermine/topiramate, and pioglitazone significantly reduced the risk of biochemical conversion to T2DM, whereas statins and nateglinide increased the risk”

 


Meta-Analysis: Neonatal, Infant, and Childhood Growth Following Metformin vs. Insulin Treatment for Gestational Diabetes

11 Aug, 2019 | 22:15h | UTC

Neonatal, infant, and childhood growth following metformin versus insulin treatment for gestational diabetes: A systematic review and meta-analysis – PLOS Medicine (free)

Commentary: Does metformin treatment for GDM adversely affect offspring? – Univadis (free registration required)

 


[Abstract Only] Study: SGLT2 Inhibitors not Associated with Increased Risk of Severe Urinary Tract Infections

11 Aug, 2019 | 21:37h | UTC

Sodium–Glucose Cotransporter-2 Inhibitors and the Risk for Severe Urinary Tract Infections: A Population-Based Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: SGLT-2 inhibitors not associated with increased risk for severe UTIs – ACP Diabetes (free) AND SGLT2 Inhibitor Use Not Linked to Increased Risk for UTI Events – Endocrinology Advisor (free) AND SGLT-2 inhibitors not associated with increased risk for severe UTI – 2 Minute Medicine (free)

 


A Clinician’s Guide to Healthy Eating for Cardiovascular Disease Prevention

8 Aug, 2019 | 07:51h | UTC

A Clinician’s Guide to Healthy Eating for Cardiovascular Disease Prevention – Mayo Clinic Proceedings: Innovations, Quality & Outcomes (free)

 


Study: Plant‐Based Diets Are Associated with a Lower Risk of Cardiovascular Disease and All‐Cause Mortality

8 Aug, 2019 | 07:44h | UTC

Plant‐Based Diets Are Associated With a Lower Risk of Incident Cardiovascular Disease, Cardiovascular Disease Mortality, and All‐Cause Mortality in a General Population of Middle‐Aged Adults – Journal of the American Heart Association (free)

Commentaries: Eating more plant-based foods may be linked to better heart health – American Heart Association (free) AND Healthy plant-based diet tied to lowered heart risk – Reuters (free)

 


[Abstract Only] Study: Metformin Use Linked to Reduced Risk for Cardiovascular Death and All-cause Mortality

7 Aug, 2019 | 07:54h | UTC

Metformin Use and Clinical Outcomes among Patients with Diabetes with or without Heart Failure or Kidney Dysfunction: Observations from the SAVOR-TIMI 53 Trial – Circulation (link to abstract – $ for full-text)

Commentaries: Metformin Use and CV Outcomes Among Diabetes Patients – American College of Cardiology (free) AND Support for metformin cardioprotective effect – Medicine Matters (free) AND Metformin Use Associated With Lower Death Risk in Type 2 Diabetes – Renal & Urology News (free)

Related: Effect of metformin on all-cause and cardiovascular mortality in patients with coronary artery diseases: a systematic review and an updated meta-analysis – Cardiovascular Diabetology (free)

 


Guideline: Primary Prevention of Cardiovascular Disease and T2DM in Patients at Metabolic Risk

2 Aug, 2019 | 03:03h | UTC

Primary Prevention of ASCVD and T2DM in Patients at Metabolic Risk: An Endocrine Society* Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free)

Commentaries: Older adults should be regularly screened for heart disease, diabetes risk – The Endocrine Society (free) AND Why older adults need regular metabolic risk screening – Medical News Today (free)

 


Amiodarone and Thyroid Physiology, Pathophysiology, Diagnosis and Management

2 Aug, 2019 | 01:39h | UTC

Amiodarone and thyroid physiology, pathophysiology, diagnosis and management – Trends in Cardiovascular Medicine (free)

 


Observational Study: Substantial and Sustained Improvements in Blood Pressure, Weight and Lipid Profiles from a Carbohydrate Restricted Diet

2 Aug, 2019 | 00:59h | UTC

Substantial and Sustained Improvements in Blood Pressure, Weight and Lipid Profiles from a Carbohydrate Restricted Diet: An Observational Study of Insulin Resistant Patients in Primary Care – Nutrients (free)

 


Study: Development and Validation of a Prediction Model for Fat Mass in Children and Adolescents

2 Aug, 2019 | 00:42h | UTC

Development and validation of a prediction model for fat mass in children and adolescents: meta-analysis using individual participant data – The BMJ (free)

Commentary: Assessing body fat in children made simpler by new equation – St. George’s University of London (free)

 


[Abstract Only] Meta-Analysis: Safety and Efficacy of Testosterone for Postmenopausal Women with Low Sexual Desire Causing Distress

29 Jul, 2019 | 20:45h | UTC

Safety and efficacy of testosterone for women: a systematic review and meta-analysis of randomised controlled trial data – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Commentaries: Testosterone may significantly improve sexual function and sexual well-being in postmenopausal women – The Lancet (free) AND Testosterone can enhance libido in postmenopausal women, new research says – CNN (free)

 

Related Commentary on Twitter

 


Management of Preexisting Diabetes in Pregnancy

27 Jul, 2019 | 20:07h | UTC

Management of preexisting diabetes in pregnancy: A Review – JAMA (free)

Related: Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes—2019 – American Diabetes Association (free) AND Diabetes and Pregnancy – Diabetes Canada Clinical Practice Guidelines Expert Committee (free) AND Current guidelines on the management of gestational diabetes mellitus: a content analysis and appraisal – BMC Pregnancy and Childbirth (free)

 


Systematic Review: Interventions for Preventing Obesity in Children

26 Jul, 2019 | 00:32h | UTC

Interventions for preventing obesity in children – Cochrane Library (free)

Summary: Do diet and physical activity strategies help prevent obesity in children (aged 0 to 18 years)? – Cochrane Library (free)

 


Cohort Study: Association of Normal-Weight Central Obesity with All-Cause and Cause-Specific Mortality Among Postmenopausal Women

25 Jul, 2019 | 01:45h | UTC

Association of Normal-Weight Central Obesity With All-Cause and Cause-Specific Mortality Among Postmenopausal Women – JAMA Network Open (free)

Commentaries: What’s New in Understanding the Risk Associated With Body Size and Shape? Pears, Apples, and Olives on Toothpicks – JAMA Network Open (free) AND Bellyfat in some postmenopausal women linked to higher death risk – UPI (free) AND Expert reaction to central obesity and mortality risk in postmenopausal women of normal weight – Science Media Centre (free)

Related Study: Distribution of Regional Body Fat and Cardiovascular Disease Risk Among Postmenopausal Women with Normal BMI (free study and commentaries)

 


Small Study Suggests Early Time‐Restricted Feeding Reduces Appetite and Increases Fat Oxidation

25 Jul, 2019 | 01:12h | UTC

Early Time‐Restricted Feeding Reduces Appetite and Increases Fat Oxidation But Does Not Affect Energy Expenditure in Humans – Obesity (free)

Commentary: Meal timing strategies appear to lower appetite, improve fat burning – The Obesity Society (free)

 


Randomized Trial: Intensive Treatment of Hyperglycemia Does Not Improve Outcomes in Patients with Acute Ischemic Stroke

24 Jul, 2019 | 09:18h | UTC

Intensive vs Standard Treatment of Hyperglycemia and Functional Outcome in Patients With Acute Ischemic Stroke: The SHINE Randomized Clinical Trial – JAMA (free for a limited period)

Commentaries: Researchers get a handle on how to control blood sugar after stroke – NIH News Releases (free) AND Study Doesn’t Support Intensive Glucose Control in Patients with Stroke and Hyperglycemia – NEJM Journal Watch (free)

 


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