Endocrinology (all articles) | Page 34 of 92 | Links Medicus Content Curation & Alerts in Medicine

CHOOSE MINIMALLY PROCESSED FOODS INSTEAD OF ULTRA-PROCESSED FOODS is one of the 10 evidence-based dietary pattern recommendations in the new excellent 2021 American Heart Association Scientific Statement on Dietary Guidance to Improve Cardiovascular Healthhttps://t.co/YgtDKz05EP

— Carlos A. Monteiro (@CMonteiro_USP) November 2, 2021

Systematic Review: GLP-1 receptor agonists and SGLT-2 inhibitors are likely to reduce the risk of death from cardiovascular disease and death from any cause in people with both diabetes and established cardiovascular disease.

29 Oct, 2021 | 09:52h | UTC

Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose co‐transporter‐2 inhibitors for people with cardiovascular disease: a network meta‐analysis – Cochrane Library

Summary: The effects of DPP-4 inhibitors, GLP-1 receptor agonists and SGLT-2 inhibitors for people with cardiovascular disease – Cochrane Library

Commentary on Twitter

The effects of DPP‐4 inhibitors, GLP‐1 receptor agonists and SGLT‐2 inhibitors for people with #CardiovascularDisease https://t.co/0FwffSCqbC New @CochraneHeart network meta-analysis looks at evidence from 31 studies. #CardiovascularResearch

— The Cochrane Library (@CochraneLibrary) October 27, 2021

RCT: In critically ill patients, an individualized glucose control targeting an ICU patient’s pre-admission usual glycemia did not demonstrate a survival benefit compared to conventional glucose control (targeting glycemia below 180 mg/dL).

27 Oct, 2021 | 01:17h | UTC

Individualised versus conventional glucose control in critically-ill patients: the CONTROLING study—a randomized clinical trial – Intensive Care Medicine

Editorial: The goal of personalized glucose control in the critically ill remains elusive – Intensive Care Medicine

Anticoagulants and diabetes agents are among the most frequent causes of emergency department visits attributed to medication harms.

27 Oct, 2021 | 01:15h | UTC

US Emergency Department Visits Attributed to Medication Harms, 2017-2019 – JAMA (link to abstract – $ for full-text)

Commentaries:

Number of emergency room visits for medication harms increases with age – MedicalResearch.com

Blood thinners, diabetes meds among top causes of drug-related ER visits – UPI

Adult-Onset Type 1 Diabetes: Current Understanding and Challenges.

26 Oct, 2021 | 01:47h | UTC

Adult-Onset Type 1 Diabetes: Current Understanding and Challenges – Diabetes Care

ADA Consensus Report: The Management of Type 1 Diabetes in Adults.

Guideline: ADA 2021 Standards of Medical Care in Diabetes

Consensus and algorithm on the diagnosis and management of Cushing’s disease: a guideline update.

26 Oct, 2021 | 01:49h | UTC

Consensus on diagnosis and management of Cushing’s disease: a guideline update – The Lancet Diabetes & Endocrinology (free registration required)

Meta-Analysis: Effectiveness of Medical Treatment for Cushing’s Syndrome

COVID-19 and Cushing’s Syndrome Recommendations

Practice recommendations for the management of the most common forms of secondary hypertension, including primary aldosteronism, renovascular hypertension, pheochromocytoma, Cushing’s syndrome, and sleep apnea

Commentary on Twitter

New—Consensus on diagnosis and management of #Cushing's disease: a guideline update https://t.co/E777qklWfl #FREE to read with registration (also FREE)

— The Lancet Diabetes & Endocrinology (@TheLancetEndo) October 20, 2021

Cluster RCT: Increasing the dietary sources of calcium and protein (by providing additional milk, yogurt, and cheese) reduced hip fractures and falls in older adults in residential care.

22 Oct, 2021 | 10:21h | UTC

Effect of dietary sources of calcium and protein on hip fractures and falls in older adults in residential care: cluster randomised controlled trial – The BMJ

News release: Increasing dairy intake reduces falls and fractures among older care home residents – British Medical Journal

Commentary on Twitter

Increasing intake of foods rich in calcium and protein such as milk, yoghurt, and cheese, reduces falls and fractures in older adults living in residential care, finds a randomised controlled trial published @bmj_latest today https://t.co/QzozG4Odjb

— BMJ Group (@bmj_company) October 21, 2021

RCT: In patients with Type 2 Diabetes, Tirzepatide is associated with reduced weight, improved glycemic control, and lower risk of hypoglycemia compared to insulin glargine.

20 Oct, 2021 | 10:13h | UTC

Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial – The Lancet (link to abstract – $ for full-text)

RCT: Once-weekly tirzepatide vs. once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes.

RCT: Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2.

RCT: Tirzepatide yielded greater glycated hemoglobin and body weight reductions compared to Semaglutide 1 mg.

Management of Diabetes Mellitus in patients with CKD: Core Curriculum 2022.

17 Oct, 2021 | 21:23h | UTC

Management of Diabetes Mellitus in Patients With CKD: Core Curriculum 2022 – American Journal of Kidney Diseases

FDA issues food industry guidance for reduction of sodium in processed and packaged foods.

15 Oct, 2021 | 02:29h | UTC

News Release: To Improve Nutrition and Reduce the Burden of Disease, FDA Issues Food Industry Guidance for Voluntarily Reducing Sodium in Processed and Packaged Foods – U.S. Food & Drug Administration

Guidance for Industry: Voluntary Sodium Reduction Goals – U.S. Food & Drug Administration

Commentaries:

FDA Issues New Guidance on Sodium Targets for Food Industry – TCTMD

Reducing Sodium Intake in the US: Healthier Lives, Healthier Future – JAMA

FDA Reduces Recommended Salt Levels in Americans’ Food – HealthDay

FDA guidance to food industry aims to reduce sodium consumption – American Heart Association

New FDA guidance aims to drastically cut salt in food supply – NBC News

Former CDC director: Low sodium salt could save millions of lives.

15 Oct, 2021 | 02:27h | UTC

Former CDC director: Low sodium salt could save millions of lives – CNN

Is salt good for you after all? The evidence says no.

#ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

Systematic Review: Altered dietary salt intake for people with chronic kidney disease.

New WHO benchmarks help countries reduce salt intake and save lives.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Meta-Analysis: Effect of Reduction in Dietary Sodium on Blood Pressure Levels

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

Meta-analysis of cohort studies: High intake of fatty acid in nuts, seeds and plant oils linked to lower risk of death.

15 Oct, 2021 | 02:22h | UTC

News release: High intake of fatty acid in nuts, seeds and plant oils linked to lower risk of death – The BMJ

Original study: Dietary intake and biomarkers of alpha linolenic acid and risk of all cause, cardiovascular, and cancer mortality: systematic review and dose-response meta-analysis of cohort studies – The BMJ

Commentaries:

Current evidence on dietary intakes of fatty acids and mortality – The BMJ

Expert reaction to systematic review and meta-analysis on consumption of dietary fatty acids (alpha linolenic acid) and risk of death – Science Media Centre

Commentary on Twitter

NEW research: A high intake of alpha linolenic acid, found mainly in nuts, seeds, and plant oils, is associated with a lower risk of death from all causes, and specifically from diseases of the heart and blood vessels, finds a study https://t.co/HGvg8dBUUN

— The BMJ (@bmj_latest) October 14, 2021

Podcast with Dr Walter Willett: CardioNutrition – Why are findings from prospective, epidemiologic cohort studies important in informing dietary recommendations?

14 Oct, 2021 | 09:49h | UTC

ACC CardiaCast: CardioNutrition – Why Are Findings From Prospective, Epidemiologic Cohort Studies Important In Informing Dietary Recommendations? – American College of Cardiology

Commentary on Twitter

In this episode of CardioNutrition, @DrOstfeld and Dr. Walter Willett discuss why findings from prospective, epidemiologic cohort studies are important in informing dietary recommendations. Learn more here: https://t.co/IfIgauGhV9 #cvPrev #cvLipids pic.twitter.com/flet8ZTwFe

— American College of Cardiology (@ACCinTouch) October 8, 2021

USPSTF draft statement revises previous guidance and now recommends against initiating low-dose aspirin use for the primary prevention of CVD in adults aged 60 years or older.

13 Oct, 2021 | 01:36h | UTC

USPSTF Draft Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease – U.S. Preventive Services Task Force

Commentaries:

Advice shifting on aspirin use for preventing heart attacks – Associated Press

Taking aspirin to prevent heart attack may cause more harm than good, task force says – NPR

Related Randomized Trials:

Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease

Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes

Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly

Related Meta-Analysis:

Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events

Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events

Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups – BMC Medicine

Related Opinions:

Aspirin for Primary Prevention: Is This the End of the Road?

Evidence evolving on aspirin as prevention – ACP Internist

Commentary on Twitter

Low Dose Aspirin in the Primary Prevention of Cardiovascular Disease: #USPSTF recommends individualized decision making between 50 and 59 years, and against aspirin use in 60 years+. What a difference a few years can make, with more data and evidence. https://t.co/3nC3jpjTDq pic.twitter.com/SN8K3Z9XJj

— Muin J. Khoury (@MuinJKhoury) October 12, 2021

M-A: Omega-3 fatty acids supplementation is associated with increased risk of atrial fibrillation.

13 Oct, 2021 | 01:27h | UTC

Effect of Long-Term Marine Omega-3 Fatty Acids Supplementation on the Risk of Atrial Fibrillation in Randomized Controlled Trials of Cardiovascular Outcomes: A Systematic Review and Meta-Analysis – Circulation (link to abstract – $ for full-text)

M-A: Omega-3 fatty acids supplementation increases the risk of atrial fibrillation in patients with lipid disorders.

More data suggests no cardiovascular benefit from Omega-3 supplementation – secondary analysis of STRENGHT trial did not show an association between achieved Omega-3 fatty acid levels and major adverse cardiovascular outcomes in patients with high cardiovascular risk.

RCT: Omega-3 supplements do not reduce cardiovascular events in elderly patients after myocardial infarction

#AHA20 – Randomized trial: High-dose Omega-3 fatty acids did not reduce the risk of cardiac events in patients at high cardiovascular risk

Meta-Analysis of Randomized Trials: Little Benefit from Omega-3 Intake to Reduce Cardiovascular Disease Risk

Commentary on Twitter

#OriginalResearch Omega-3 fatty acid supplementation is associated with increased risk of #AFib in meta-analysis of RCTs https://t.co/knv0P0lmnC #AHAJournals @bagencer @Hopitaux_unige @CMAlbertEP @CedarsSinai @BrighamWomens @HarvardChanSPH @harvardmed pic.twitter.com/5VIklN8lm8

— Circulation (@CircAHA) October 6, 2021

Review: Optimal diet for cardiovascular and planetary health.

13 Oct, 2021 | 01:22h | UTC

Optimal diet for cardiovascular and planetary health – Heart

Large observational study suggests sleeve gastrectomy may be safer compared to gastric bypass in patients with severe obesity.

7 Oct, 2021 | 10:26h | UTC

Comparative Safety of Sleeve Gastrectomy and Gastric Bypass Up to 5 Years After Surgery in Patients With Severe Obesity – JAMA Surgery (free for a limited period)

Commentaries:

Compared to What?—Novel Methods to Approach Randomization for Long-term Bariatric Surgery Outcomes – JAMA Surgery (free for a limited period)

Of two common weight loss surgeries, one is safer but less effective – Michigan Medicine

Different risks and benefits leading to similar costs after sleeve gastrectomy and roux-en-y gastric bypass.

Laparoscopic roux-en-y gastric bypass vs. laparoscopic sleeve gastrectomy: 5-year outcomes of merged data from two randomized clinical trials

Randomized trial: no difference in quality of life and slightly greater weight loss with roux-en-y gastric bypass compared to laparoscopic sleeve gastrectomy at 7 years

Cohort study: comparing the 5-year diabetes outcomes of sleeve gastrectomy and gastric bypass

Cohort study: interventions and operations 5 years after bariatric surgery

Cohort study: risk of operative and nonoperative interventions after roux-en-y gastric bypass vs. vertical sleeve gastrectomy

Randomized trial: gastric bypass superior to sleeve gastrectomy for remission of type 2 diabetes

Research: laparoscopic sleeve gastrectomy vs laparoscopic roux-en-y gastric bypass

Commentary on Twitter

Study suggests that the safety benefits of sleeve gastrectomy persist up to 5 years after surgery; this information may help patients and surgeons make informed treatment decisions https://t.co/JuRQGh3byz

— JAMA Surgery (@JAMASurgery) October 6, 2021

The diagnosis and management of endocrine side effects of immune checkpoint inhibitors.

6 Oct, 2021 | 08:44h | UTC

The Diagnosis and Management of Endocrine Side Effects of Immune Checkpoint Inhibitors – Deutsches Ärzteblatt International

COVID-19 and metabolic disease: mechanisms and clinical management.

5 Oct, 2021 | 10:03h | UTC

COVID-19 and metabolic disease: mechanisms and clinical management – The Lancet Diabetes & Endocrinology

Cohort study: Statin therapy initiation linked to increased risk of diabetes progression.

5 Oct, 2021 | 08:56h | UTC

Association of Statin Therapy Initiation With Diabetes Progression: A Retrospective Matched-Cohort Study – JAMA Internal Medicine

Commentaries:

Statin Therapy Initiation and Diabetes Progression – American College of Cardiology

Statin Initiation Linked to Greater Progression of Diabetes – HealthDay

Diabetes progression with initiation of statins – MedicalRessearch.com

Meta-Analysis: Medications that Reduce or Increase the Risk of New Onset Diabetes

Observational Study Points to an Increased Risk of Diabetes Among Patients Using Statins

Another Observational Study Showing Association of Statin Use with Risk of New‐Onset Diabetes Mellitus

Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes

Commentary on Twitter

Large retrospective matched-cohort study found that #statin use was associated with a higher risk of #diabetes treatment escalation and an increased risk of #hyperglycemic complications https://t.co/lFLz7rVfpd

— JAMA Internal Medicine (@JAMAInternalMed) October 4, 2021

RCT: Effects of 30 days of ketogenic diet on body composition, muscle strength, muscle area, metabolism, and performance in semi-professional soccer players.

5 Oct, 2021 | 08:47h | UTC

Effects of 30 days of ketogenic diet on body composition, muscle strength, muscle area, metabolism, and performance in semi-professional soccer players – Journal of the International Society of Sports Nutrition

WHO prioritizes access to diabetes and cancer treatments in new Essential Medicines Lists.

3 Oct, 2021 | 22:46h | UTC

News Release: WHO prioritizes access to diabetes and cancer treatments in new Essential Medicines Lists – World Health Organization

Report: WHO model list of essential medicines – 22nd list, 2021 – World Health Organization

Commentary: For the first time, WHO committee recommends action on high-priced essential medicines – STAT

Commentary on Twitter (thread – click for more)

🆕 WHO 2021 Essential Medicines Lists have 20 new medicines for adults & 17 for children, incl. insulin analogues, new oral medicines for diabetes & medicines for cancer treatment https://t.co/LfWwHEZtuM pic.twitter.com/HMFOP8ioBf

— World Health Organization (WHO) (@WHO) October 1, 2021

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