M-A: Omega-3 fatty acids supplementation is associated with increased risk of atrial fibrillation.

Effect of Long-Term Marine Omega-3 Fatty Acids Supplementation on the Risk of Atrial Fibrillation in Randomized Controlled Trials of Cardiovascular Outcomes: A Systematic Review and Meta-Analysis – Circulation (link to abstract – $ for full-text)

Related:

M-A: Omega-3 fatty acids supplementation increases the risk of atrial fibrillation in patients with lipid disorders.

More data suggests no cardiovascular benefit from Omega-3 supplementation – secondary analysis of STRENGHT trial did not show an association between achieved Omega-3 fatty acid levels and major adverse cardiovascular outcomes in patients with high cardiovascular risk.

RCT: Omega-3 supplements do not reduce cardiovascular events in elderly patients after myocardial infarction

#AHA20 – Randomized trial: High-dose Omega-3 fatty acids did not reduce the risk of cardiac events in patients at high cardiovascular risk

Meta-Analysis of Randomized Trials: Little Benefit from Omega-3 Intake to Reduce Cardiovascular Disease Risk

Commentary on Twitter

#OriginalResearch Omega-3 fatty acid supplementation is associated with increased risk of #AFib in meta-analysis of RCTs https://t.co/knv0P0lmnC #AHAJournals @bagencer @Hopitaux_unige @CMAlbertEP @CedarsSinai @BrighamWomens @HarvardChanSPH @harvardmed pic.twitter.com/5VIklN8lm8

— Circulation (@CircAHA) October 6, 2021