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Endocrinology (all articles)

Guideline: ADA 2022 Standards of Medical Care in Diabetes.

24 Dec, 2021 | 13:38h | UTC

Guideline Homepage: ADA 2022 Standards of Medical Care in Diabetes – American Diabetes Association

Introduction: Standards of Medical Care in Diabetes—2022

Summary of Revisions: Standards of Medical Care in Diabetes—2022

Standards of Medical Care in Diabetes—2022 Guideline Abridged for Primary Care Providers

Video Summary: Standards of Care in Diabetes – 2022

  1. Improving Care and Promoting Health in Populations
  2. Classification and Diagnosis of Diabetes 
  3. Prevention or Delay of Type 2 Diabetes and Associated Comorbidities
  4. Comprehensive Medical Evaluation and Assessment of Comorbidities
  5. Facilitating Behavior Change and Well-being to Improve Health Outcomes
  6. Glycemic Targets
  7. Diabetes Technology
  8. Obesity and Weight Management for the Prevention and Treatment of Type 2 Diabetes
  9. Pharmacologic Approaches to Glycemic Treatment
  10. Cardiovascular Disease and Risk Management
  11. Chronic Kidney Disease and Risk Management
  12. Retinopathy, Neuropathy, and Foot Care
  13. Older Adults
  14. Children and Adolescents
  15. Management of Diabetes in Pregnancy
  16. Diabetes Care in the Hospital
  17. Diabetes Advocacy

 

Commentaries on Twitter

 

AAN Guideline: Oral and topical treatment of painful diabetic polyneuropathy.

8 Jan, 2022 | 23:18h | UTC

Oral and Topical Treatment of Painful Diabetic Polyneuropathy: Practice Guideline Update Summary: Report of the AAN Guideline Subcommittee – Neurology

News Release: AAN Issues Guideline for Treatment of Painful Diabetic Neuropathy – American Academy of Neurology

 

NICE Guideline | Type 2 diabetes in adults: management.

17 Dec, 2021 | 08:45h | UTC

Type 2 diabetes in adults: management – National Institute for Health and Care Excellence

Related: Guideline: ADA 2021 Standards of Medical Care in Diabetes

 

Review: Impact of obesity in critical illness.

16 Dec, 2021 | 08:45h | UTC

Impact of Obesity in Critical Illness – CHEST

 

M-A: Pharmacotherapy for adults with overweight and obesity – “phentermine–topiramate and GLP-1 receptor agonists proved the best drugs in reducing weight”.

15 Dec, 2021 | 08:30h | UTC

Pharmacotherapy for adults with overweight and obesity: a systematic review and network meta-analysis of randomised controlled trials – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Review | Anti-obesity drug discovery: advances and challenges.

14 Dec, 2021 | 08:49h | UTC

Anti-obesity drug discovery: advances and challenges – Nature Reviews Drug Discovery (free for a limited period – if the link is paywalled, try this one)

 

Blood sugar targets in surgical intensive care: management and special considerations in patients with diabetes.

9 Dec, 2021 | 10:06h | UTC

Blood Sugar Targets in Surgical Intensive Care – Deutsches Ärzteblatt International

 

Consensus on Practical Management of Parathyroid Disorders in Adults and in Pregnancy.

5 Dec, 2021 | 23:43h | UTC

European Expert Consensus on Practical Management of Specific Aspects of Parathyroid Disorders in Adults and in Pregnancy: Recommendations of the ESE Educational Program of Parathyroid Disorders – European Journal of Endocrinology

 

The ‘ten commandments’ for the 2021 ESC Guidelines on CVD prevention.

2 Dec, 2021 | 09:45h | UTC

The ‘ten commandments’ for the 2021 ESC Guidelines on CVD prevention – European Heart Journal

Original Article: #ESCCongress – 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice.

 

M-A: Association of Glucagon-like Peptide 1 Analogs and agonists administered for obesity with weight loss and adverse events.

28 Nov, 2021 | 21:09h | UTC

Association of Glucagon-like Peptide 1 Analogs and Agonists Administered for Obesity with Weight Loss and Adverse Events: A Systematic Review and Network Meta-analysis – EClinicalMedicine

 

Diets for weight management in adults with type 2 diabetes: an umbrella review of published meta-analyses and systematic review of trials of diets for diabetes remission – “Published meta-analyses of hypocaloric diets for weight management in people with type 2 diabetes do not support any particular macronutrient profile or style over others”.

25 Nov, 2021 | 10:19h | UTC

Diets for weight management in adults with type 2 diabetes: an umbrella review of published meta-analyses and systematic review of trials of diets for diabetes remission – Diabetologia

News Release: Analysis shows low energy diets with formula meal replacements are the most effective methods for weight management and remission in adults with type 2 diabetes – Diabetologia

 

Commentary on Twitter

https://twitter.com/DiabetologiaJnl/status/1461773268231147521

 

Cohort study found the risk of myocardial infarction may be best predicted by the number of apolipoprotein B containing lipoproteins.

24 Nov, 2021 | 08:41h | UTC

Association of Apolipoprotein B–Containing Lipoproteins and Risk of Myocardial Infarction in Individuals With and Without Atherosclerosis: Distinguishing Between Particle Concentration, Type, and Content – JAMA Cardiology (link to abstract – $ for full-text)

Commentaries:

ApoB Gains Ground as Best Lipid Predictor of MI Risk – TCTMD

Study finds risk of MI best captured by number of apolipoprotein B lipoproteins – MedicalResearch

 

Commentary on Twitter

 

RCT: A brief 5:2 diet advice resulted in similar weight loss at one year vs. a standard multicomponent weight-management advice (-2.6kg vs. -1.9kg, p = 0.37).

24 Nov, 2021 | 08:29h | UTC

A randomised controlled trial of the 5:2 diet – PLOS One

News Release: Brief 5:2 diet advice is as effective as traditional GP advice, but people like it better, according to new study – Queen Mary University of London

Commentary: Fasting 2 days a week can help obese people keep off the weight with modest results, study finds – CNN

 

Individual participant data meta-analysis of major randomized trials showed that treatment of hypertension with ACEIs or ARBs reduced the risk of new-onset type 2 diabetes compared to other drugs.

17 Nov, 2021 | 08:29h | UTC

Blood pressure lowering and risk of new-onset type 2 diabetes: an individual participant data meta-analysis – The Lancet

Commentaries:

Expert reaction to an individual participant data meta-analysis on blood pressure lowering and risk of onset of type-2 diabetes – Science Media Centre

Blood pressure drugs could prevent type 2 diabetes, study finds – The Guardian

 

Phase 2 RCT: Once-weekly cagrilintide is effective for weight management in people with overweight and obesity.

17 Nov, 2021 | 08:23h | UTC

Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial – The Lancet (link to abstract – $ for full-text)

 

RCT: Adjustable intragastric balloon resulted in significant weight loss at 32 weeks, but intolerance caused early removal of the device in 17% of patients, and device-related serious adverse events were observed in 4% of patients.

17 Nov, 2021 | 08:26h | UTC

Adjustable intragastric balloon for treatment of obesity: a multicentre, open-label, randomised clinical trial – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter

 

New WHO report maps barriers to insulin availability and suggests actions to promote universal access – “100 years after its discovery, insulin still out of reach for many living with diabetes”.

16 Nov, 2021 | 08:34h | UTC

News Release: New WHO report maps barriers to insulin availability and suggests actions to promote universal access – World Health Organization

Report: Keeping the 100-year-old promise: making insulin access universal – World Health Organization

Commentary: Half the People Living with Diabetes Can’t Afford Insulin, WHO Report Shows – Health Policy Watch

Related:

Editorial | Insulin for all: a hope yet to be realized.

One hundred years of insulin therapy.

The state of diabetes treatment coverage in 55 low-income and middle-income countries – fewer than one in ten people with diabetes in LMICs receive comprehensive care such as low-cost medicines to reduce blood sugar, blood pressure and cholesterol levels, in addition to counseling on diet, exercise and weight.

 

Commentary on Twitter (thread – click for more)

https://twitter.com/WHO/status/1459194472022122500

 

#AHA21 – [News release – not published yet] RCT: Long-term, low-dose aspirin did not affect risk of dementia in adults with type 2 diabetes.

16 Nov, 2021 | 08:30h | UTC

Long-term, low-dose aspirin did not affect risk of dementia in adults with type 2 diabetes – American Heart Association

Original Study: Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes

 

Review | Glycemic management in diabetes: old and new approaches.

16 Nov, 2021 | 08:17h | UTC

Glycaemic management in diabetes: old and new approaches – The Lancet Diabetes & Endocrinology (free registration required)

 

Commentary on Twitter

 

EMA Recommendation: Dapagliflozin 5mg should no longer be used for the treatment of Type 1 Diabetes Mellitus due to increased risk of diabetic ketoacidosis.

12 Nov, 2021 | 10:28h | UTC

Forxiga (dapagliflozin) 5mg should no longer be used for the treatment of Type 1 Diabetes Mellitus – European Medicines Agency

 

Cohort study: In patients with nonalcoholic steatohepatitis and obesity, bariatric surgery was associated with lower risk of incident major adverse liver outcomes and major adverse cardiovascular events.

12 Nov, 2021 | 10:24h | UTC

Association of Bariatric Surgery With Major Adverse Liver and Cardiovascular Outcomes in Patients With Biopsy-Proven Nonalcoholic Steatohepatitis – JAMA (free for a limited period)

Editorial: Bariatric Surgery as a Strategy for Improving Outcomes in Nonalcoholic Steatohepatitis – JAMA (free for a limited period)

 

Commentary on Twitter

 

Cohort study: Among older adults with diabetes who were hospitalized for common medical conditions, intensification of diabetes medications at hospital discharge was associated with an increased short-term risk of severe hypoglycemia events but was not associated with improved glycemic control.

12 Nov, 2021 | 09:51h | UTC

Intensification of Diabetes Medications at Hospital Discharge and Clinical Outcomes in Older Adults in the Veterans Administration Health System – JAMA Network Open

 

Cohort study: After an episode of severe hypoglycemia in older adults with diabetes, sulfonylurea or insulin treatment deintensification occurred in fewer than 50% of episodes.

12 Nov, 2021 | 09:53h | UTC

Deintensification of Treatment With Sulfonylurea and Insulin After Severe Hypoglycemia Among Older Adults With Diabetes – JAMA Network Open

 

Commentary on Twitter

 

M-A: Low vitamin D levels do not aggravate COVID-19 risk or death, and vitamin D supplementation does not improve outcomes in hospitalized patients with COVID-19.

11 Nov, 2021 | 08:53h | UTC

Low vitamin D levels do not aggravate COVID-19 risk or death, and vitamin D supplementation does not improve outcomes in hospitalized patients with COVID-19: a meta-analysis and GRADE assessment of cohort studies and RCTs – Nutritional Journal

 

Choosing Wisely for Thyroid Conditions: Ten things clinicians and patients should question – “Do not order thyroid ultrasound for nodule detection in patients without thyroid anatomic anomalies on clinical examination”.

9 Nov, 2021 | 01:11h | UTC

Choosing Wisely for Thyroid Conditions: Recommendations of the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 

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