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Endocrinology (all articles)

Long-term safety and efficacy of anacetrapib in patients with atherosclerotic vascular disease.

28 Jan, 2022 | 08:05h | UTC

Long-term safety and efficacy of anacetrapib in patients with atherosclerotic vascular disease – European Heart Journal

 


Perspective: From vaginal laser treatment to spa breaks – it’s the great menopause gold rush.

27 Jan, 2022 | 09:36h | UTC

From vaginal laser treatment to spa breaks – it’s the great menopause gold rush – The Guardian

 


ESC Position Statement: Cardiovascular effects of doping substances, commonly prescribed medications, and ergogenic aids in relation to sports.

27 Jan, 2022 | 09:43h | UTC

Cardiovascular effects of doping substances, commonly prescribed medications and ergogenic aids in relation to sports: a position statement of the sport cardiology and exercise nucleus of the European Association of Preventive Cardiology – European Journal of Preventive Cardiology

News Release: Athletes warned against potential dangers of natural supplements – European Society of Cardiology

 


Short-term glucocorticoid-related side effects and adverse reactions: a narrative review and practical approach.

27 Jan, 2022 | 09:18h | UTC

Short-term glucocorticoid-related side effects and adverse reactions: a narrative review and practical approach – Swiss Medical Weekly

 


Long-term results of RCT: GH replacement with once-weekly somapacitan is comparable to daily GH in children with growth hormone deficiency.

25 Jan, 2022 | 09:07h | UTC

Effective GH replacement with once-weekly somapacitan vs daily GH in children with GHD: 3-year results from REAL 3 – The Journal of Clinical Endocrinology & Metabolism

 


Clinical review of subcutaneous Semaglutide for obesity.

24 Jan, 2022 | 07:54h | UTC

Clinical review of subcutaneous semaglutide for obesity – Journal of Clinical Pharmacy and Therapeutics

 


RCT: In very young children with Type 1 Diabetes, a hybrid closed-loop therapy (“artificial pancreas”) resulted in better glycemic control without increased risk of hypoglycemia vs. sensor-augmented pump therapy.

20 Jan, 2022 | 09:07h | UTC

Randomized Trial of Closed-Loop Control in Very Young Children with Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Artificial pancreas proves ‘life-changing’ for very young children with type 1 diabetes and their families – University of Cambridge

 


Consensus Statement: Exercise/physical activity in individuals with Type 2 Diabetes.

20 Jan, 2022 | 08:51h | UTC

Exercise/Physical Activity in Individuals with Type 2 Diabetes: A Consensus Statement from the American College of Sports Medicine – Medicine & Science in Sports & Exercise

 

Commentary from the author on Twitter

 


Review: Diagnosis and treatment of polycystic ovary syndrome.

20 Jan, 2022 | 08:54h | UTC

Diagnosis and Treatment of Polycystic Ovary Syndrome – JAMA (free for a limited period)

 


M-A: Association of Sodium-Glucose Cotransporter 2 Inhibitors with cardiovascular outcomes in patients with Type 2 Diabetes and other risk factors for cardiovascular disease.

20 Jan, 2022 | 08:42h | UTC

Association of Sodium-Glucose Cotransporter 2 Inhibitors With Cardiovascular Outcomes in Patients With Type 2 Diabetes and Other Risk Factors for Cardiovascular Disease: A Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 


Association of hormonal contraceptive use with adverse health outcomes: an umbrella review of meta-analyses of randomized clinical trials and cohort studies.

18 Jan, 2022 | 09:29h | UTC

Association of Hormonal Contraceptive Use With Adverse Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials and Cohort Studies – JAMA Network Open

 


Cohort study: In patients who underwent bariatric surgery, those submitted to gastric bypass were slightly more likely to remain free of obesity-related medications during follow-up compared with those who underwent sleeve gastrectomy.

18 Jan, 2022 | 09:31h | UTC

Medication Use for Obesity-Related Comorbidities After Sleeve Gastrectomy or Gastric Bypass – JAMA Surgery (link to abstract – $ for full-text)

Commentary: Gastric Bypass Tied to Modest Shift in Need for Comorbidity Meds – MedPage Today (free registration required)

 

Commentary on Twitter

 


Treating Acne in Transgender Persons Receiving Testosterone: A Practical Guide.

18 Jan, 2022 | 09:23h | UTC

Treating Acne in Transgender Persons Receiving Testosterone: A Practical Guide – American Journal of Clinical Dermatology

 


RCT: Oral Vitamin D supplementation (60.000 IU per month) did not reduce mortality in patients 60 years or older (unscreened individuals in Australia, many without insufficiency, average 30ng/mL). Exploratory analyses pointed towards an increased risk of death from cancer.

16 Jan, 2022 | 23:13h | UTC

The D-Health Trial: a randomised controlled trial of the effect of vitamin D on mortality – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Related:

Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention

Association between vitamin D supplementation and mortality: systematic review and meta-analysis – The BMJ

USPSTF Draft Statement: Insufficient evidence to recommend multivitamin supplements for the prevention of CVD or cancer. The statement also recommends against the use of beta-carotene (increases risk of CVD mortality and lung cancer) or vitamin E (clear evidence of no benefit)

Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases

Research: Circulating vitamin D concentration and risk of seven cancers

Research: Vitamin D and risk of total and site specific cancers

 


ERAS Guidelines for perioperative care in bariatric surgery.

16 Jan, 2022 | 23:21h | UTC

Guidelines for Perioperative Care in Bariatric Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations: A 2021 Update – World Journal of Surgery

Related: Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines

 

Commentary on Twitter

 


RCT: Vitamin D supplementation is not beneficial for the prevention of cardiovascular disease and cancer.

16 Jan, 2022 | 23:11h | UTC

Vitamin D supplementation and prevention of cardiovascular disease and cancer in the Finnish Vitamin D Trial-a randomized controlled trial – American Journal of Clinical Nutrition

News Release: Five years of high-dose vitamin D did not affect incidence of cardiovascular disease or cancer – University of Eastern Finland

Related:

Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention

Association between vitamin D supplementation and mortality: systematic review and meta-analysis – The BMJ

USPSTF Draft Statement: Insufficient evidence to recommend multivitamin supplements for the prevention of CVD or cancer. The statement also recommends against the use of beta-carotene (increases risk of CVD mortality and lung cancer) or vitamin E (clear evidence of no benefit)

Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases

Research: Circulating vitamin D concentration and risk of seven cancers

Research: Vitamin D and risk of total and site specific cancers

 


Perspective: Primary care providers should prescribe aspirin to prevent cardiovascular disease based on benefit−risk ratio, not age.

16 Jan, 2022 | 22:53h | UTC

Primary care providers should prescribe aspirin to prevent cardiovascular disease based on benefit−risk ratio, not age – Family Medicine and Community Health

Commentaries:

Researchers urge: ‘Prescribe aspirin based on benefit-to-risk not age’ – Florida Atlantic University

Preventive Aspirin Should Be Based on Benefit, Not Age – HealthDay

Related: USPSTF draft statement revises previous guidance and now recommends against initiating low-dose aspirin use for the primary prevention of CVD in adults aged 60 years or older.

 


Assessment and treatment of thyroid disorders in pregnancy and the postpartum period.

16 Jan, 2022 | 22:42h | UTC

Assessment and treatment of thyroid disorders in pregnancy and the postpartum period – Nature Reviews Endocrinology (if the link is paywalled, try this one)

 

Commentary on Twitter

 


RCT: In patients with acromegaly who previously tolerated and responded to both regimens, oral octreotide was non-inferior for maintaining biochemical response and symptomatic control compared to injectable somatostatin receptor ligands.

14 Jan, 2022 | 07:55h | UTC

Maintenance of response to oral octreotide compared with injectable somatostatin receptor ligands in patients with acromegaly: a phase 3, multicentre, randomised controlled trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

 


The year in cardiovascular medicine 2021: diabetes and metabolic disorders.

13 Jan, 2022 | 08:33h | UTC

The year in cardiovascular medicine 2021: diabetes and metabolic disorders – European Heart Journal

 


The year in cardiovascular medicine 2021: dyslipidemia.

13 Jan, 2022 | 08:30h | UTC

The year in cardiovascular medicine 2021: dyslipidemia – European Heart Journal

 


M-A: Intermittent Fasting and Obesity-Related Health Outcomes.

13 Jan, 2022 | 08:22h | UTC

Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials – JAMA Network Open

 


RCT: High-dose weekly Semaglutide (2.4 mg) resulted in increased weight loss compared to daily Liraglutide (3.0 mg).

12 Jan, 2022 | 08:55h | UTC

Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial – JAMA (free for a limited period)

 

Commentary on Twitter

 


Cohort Study: Higher consumption of olive oil linked to lower risk of cardiovascular, cancer, and all-cause mortality.

12 Jan, 2022 | 08:41h | UTC

Consumption of Olive Oil and Risk of Total and Cause-Specific Mortality Among U.S. Adults – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries:

Higher olive oil intake associated with lower risk of CVD mortality – American College of Cardiology

Higher Olive Oil Intake May Be Associated With Lower Risk of CVD Mortality – American College of Cardiology

 


AHA Scientific Statement: Comprehensive management of cardiovascular risk factors for adults with Type 2 Diabetes.

11 Jan, 2022 | 02:40h | UTC

Comprehensive Management of Cardiovascular Risk Factors for Adults With Type 2 Diabetes: A Scientific Statement From the American Heart Association – Circulation

News Release: Fewer than 1 in 5 adults with Type 2 diabetes in the U.S. are meeting optimal heart health targets – American Heart Association

 


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