Endocrinology (all articles) | Page 31 of 92 | Links Medicus Content Curation & Alerts in Medicine

Personal View | Effective, disease-modifying, clinical approaches to patients with mild-to-moderate hypertriglyceridemia.

22 Feb, 2022 | 08:17h | UTC

Effective, disease-modifying, clinical approaches to patients with mild-to-moderate hypertriglyceridaemia – The Lancet Diabetes & Endocrinology (free for a limited period)

Dietary carbohydrate and the risk of type 2 diabetes: an updated systematic review and dose–response meta-analysis of prospective cohort studies.

22 Feb, 2022 | 08:16h | UTC

Dietary carbohydrate and the risk of type 2 diabetes: an updated systematic review and dose–response meta-analysis of prospective cohort studies – Scientific Reports

RCT: Advising overweight patients to increase sleep duration may reduce caloric intake.

21 Feb, 2022 | 09:27h | UTC

Effect of Sleep Extension on Objectively Assessed Energy Intake Among Adults With Overweight in Real-life Settings: A Randomized Clinical Trial – JAMA Internal Medicine

News Release: Getting more sleep reduces caloric intake, a game changer for weight loss programs – University of Chicago Medical Center

Commentaries:

Cut nearly 300 calories a day by doing something you already do – CNN

Individualized Sleep Counseling Can Aid Weight Loss in Overweight – HealthDay

Commentary on Twitter

In this randomized clinical trial of overweight adults who habitually sleep <6.5 hours per night, sleep extension reduced daily energy intake by ~270 kcal. Maintaining adequate sleep duration could be a viable intervention to prevent or reverse obesity. https://t.co/4nURTFSMO0 pic.twitter.com/jXaRx7wOdG

— JAMA Internal Medicine (@JAMAInternalMed) February 7, 2022

Expert Review | The importance of nutrition in pregnancy and lactation: lifelong consequences.

21 Feb, 2022 | 08:38h | UTC

The importance of nutrition in pregnancy and lactation: lifelong consequences – The American Journal of Obstetrics & Gynecology

NICE Updated Guidance: Management of Type 2 Diabetes.

18 Feb, 2022 | 08:41h | UTC

Type 2 diabetes in adults: management – National Institute for Health and Care Excellence

Cohort Study: Osteoporosis and its association with cardiovascular disease, respiratory disease, and cancer.

18 Feb, 2022 | 08:24h | UTC

Osteoporosis and Its Association With Cardiovascular Disease, Respiratory Disease, and Cancer: Findings From the UK Biobank Prospective Cohort Study – Mayo Clinic Proceedings (link to abstract – $ for full-text)

Meta-analysis finds the overall prevalence of statin intolerance is around 9% and identifies the most common risk factors.

17 Feb, 2022 | 10:07h | UTC

Prevalence of statin intolerance: a meta-analysis – European Heart Journal

Commentaries:

Study shows the true prevalence of statin intolerance worldwide is between 6 to 10% – News Medical / European Society of Cardiology

Expert reaction to study looking at statin intolerance – Science Media Centre

Side effect patterns in a crossover trial of statin, placebo, and no treatment – This N-of-1 trial, now published in full, suggests the nocebo effect causes most of statins muscle adverse effects.

#AHA20 – In patients who had discontinued statins because of side effects, a N-of-1 trial of a statin, placebo, or no treatment found that side effects often attributed to statins were the same for those taking a placebo

Commentary on Twitter

Statin intolerance is “over-estimated and over-diagnosed”. World’s largest study shows less than 10% suffer side-effects caused by statins https://t.co/pcVk8YI3I3 @escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes #CVD #Riskfactors pic.twitter.com/b3nFWsc74d

— European Society of Cardiology Journals (@ESC_Journals) February 16, 2022

A novel diabetes typology: towards precision diabetology from pathogenesis to treatment.

17 Feb, 2022 | 08:31h | UTC

A novel diabetes typology: towards precision diabetology from pathogenesis to treatment – Diabetologia

RCT: Effects of a 6-month, low-carbohydrate diet on glycemic control, body composition, and cardiovascular risk factors in patients with type 2 diabetes.

13 Feb, 2022 | 22:35h | UTC

Effects of a 6-month, low-carbohydrate diet on glycaemic control, body composition, and cardiovascular risk factors in patients with type 2 diabetes: An open-label randomized controlled trial – Diabetes, Obesity and Metabolism

FIMS / EFSMA Joint position statement on the International Olympic Committee framework on fairness, inclusion and non-discrimination based on gender identity and sex variations.

13 Feb, 2022 | 22:17h | UTC

Joint position statement of the International Federation of Sports Medicine (FIMS) and European Federation of Sports Medicine Associations (EFSMA) on the IOC framework on fairness, inclusion and non-discrimination based on gender identity and sex variations – BMJ Open Sport & Exercise Medicine

Original Guidance: IOC Framework on fairness, inclusion and non-discrimination on the basis of gender identity and sex variations – International Olympic Committee

Commentary: International Olympic Committee transgender guidance criticised by medical experts – BBC

Commentary on Twitter

You do not have to agree with all content in this position statement. But surely we can agree that we need further debate and discussion (and consultation with all stakeholders) to protect the rights of all athletes. #OpenAccess ➡️ https://t.co/xIfnsyk7FV #Diversity #Inclusion pic.twitter.com/2c9S8lGCoa

— BMJ Open Sport & Exercise Medicine (@BMJOpenSEM) January 20, 2022

Review: Global accessibility of therapeutics for diabetes mellitus.

13 Feb, 2022 | 21:51h | UTC

Global accessibility of therapeutics for diabetes mellitus – Nature Reviews Endocrinology (if the link is paywalled, try this one)

New WHO report maps barriers to insulin availability and suggests actions to promote universal access – “100 years after its discovery, insulin still out of reach for many living with diabetes”.

Editorial | Insulin for all: a hope yet to be realized.

One hundred years of insulin therapy.

The state of diabetes treatment coverage in 55 low-income and middle-income countries – fewer than one in ten people with diabetes in LMICs receive comprehensive care such as low-cost medicines to reduce blood sugar, blood pressure and cholesterol levels, in addition to counseling on diet, exercise and weight.

Guideline for the management of pediatric Graves’ disease.

11 Feb, 2022 | 08:24h | UTC

2022 European Thyroid Association Guideline for the management of pediatric Graves’ disease – European Thyroid Journal

RCT: Subcutaneous Tirzepatide added to titrated Insulin Glargine improves glycemic control in patients with Type 2 Diabetes.

10 Feb, 2022 | 10:00h | UTC

Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Tirzepatide for Patients With Type 2 Diabetes – JAMA

Commentary: SURPASS-5 Data: Tirzepatide Plus Insulin Glargine Improve Glycemic Control in T2D – AJMC

RCT: In patients with Type 2 Diabetes, Tirzepatide is associated with reduced weight, improved glycemic control, and lower risk of hypoglycemia compared to insulin glargine.

RCT: Once-weekly tirzepatide vs. once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes.

RCT: Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2.

RCT: Tirzepatide yielded greater glycated hemoglobin and body weight reductions compared to Semaglutide 1 mg.

Position statement on the care of the athlete and athletic person with diabetes.

10 Feb, 2022 | 08:49h | UTC

American Medical Society for Sports Medicine Position Statement on the Care of the Athlete and Athletic Person With Diabetes – Clinical Journal of Sport Medicine

Podcast: Dyslipidemia in Children.

8 Feb, 2022 | 08:33h | UTC

#41: The Good, the Bad, and the Fasting: Dyslipidemia with Dr. Stephen Daniels – The Cribsiders Pediatric Medicine

Guideline: Management of hypertension and renin-angiotensin-aldosterone system blockade in adults with diabetic kidney disease.

4 Feb, 2022 | 08:49h | UTC

Management of hypertension and renin-angiotensin-aldosterone system blockade in adults with diabetic kidney disease: Association of British Clinical Diabetologists and the Renal Association UK guideline update 2021 – BMC Nephrology

Cross-sectional analysis: increased visceral adipose tissue in adults linked to reduced cognitive scores.

3 Feb, 2022 | 08:41h | UTC

Evaluation of Adiposity and Cognitive Function in Adults – JAMA Network Open

Commentaries:

Excess Body Fat Tied to Lower Cognitive Scores in Adults – HealthDay

Expert reaction to study looking at the association between body fat and cognition in adults – Science Media Centre

Commentary on Twitter

In this study, excess body fat was associated with lower cognitive test performance, independent of other cardiovascular risk factors and MRI-detected vascular brain injury cognitive scores. #adiposity https://t.co/xNJbOa8rbK

— JAMA Network Open (@JAMANetworkOpen) February 1, 2022

Review: Diagnosis and treatment of acromegaly.

3 Feb, 2022 | 08:34h | UTC

Diagnosis and Treatment of Acromegaly: An Update – Mayo Clinic Proceedings

Review: Prevention of atherosclerosis from childhood.

2 Feb, 2022 | 08:12h | UTC

Prevention of atherosclerosis from childhood – Nature Reviews Cardiology (if the link is paywalled, try this one)

Review: Primary care-based cardiovascular disease risk management after adverse pregnancy outcomes.

1 Feb, 2022 | 08:29h | UTC

Primary Care–Based Cardiovascular Disease Risk Management After Adverse Pregnancy Outcomes: a Narrative Review – Journal of General Internal Medicine (if the link is paywalled, try this one)

Commentary: Better management of long-term heart disease risk needed following complicated pregnancies – Boston Medical Center

A national cohort study in Sweden showed pregnancy complications (preeclampsia or eclampsia, gestational hypertension, gestational diabetes, preterm birth, small for gestational age, and stillbirth) are associated with increased risk of cardiovascular disease later in life.

AHA Scientific Statement | Adverse Pregnancy Outcomes and Cardiovascular Disease Risk

Consensus statement: Cardiovascular health after menopause transition, pregnancy disorders, and other gynecologic conditions

Cohort Study: Preeclampsia and Cardiovascular Disease

Cohort Study: Cardiovascular Disease After Hypertensive Disorders of Pregnancy Largely Explained by Conventional Cardiovascular Risk Factors (recent studies on the subject)

RCT: Vitamin D supplementation for older adults (mean age 67 years) for 5 years reduced the risk of autoimmune diseases by 22%. Absolute risk in the treatment group was 0.95% vs. 1.19% in the placebo group.

30 Jan, 2022 | 14:30h | UTC

Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial – The BMJ

Commentary: Vitamin D and fish oil supplements may help prevent autoimmune disease, study says – CNN

RCT: Oral Vitamin D supplementation (60.000 IU per month) did not reduce mortality in patients 60 years or older (unscreened individuals in Australia, many without insufficiency, average 30ng/mL). Exploratory analyses pointed towards an increased risk of death from cancer.

RCT: Vitamin D supplementation is not beneficial for the prevention of cardiovascular disease and cancer.

USPSTF Draft Statement: Insufficient evidence to recommend multivitamin supplements for the prevention of CVD or cancer. The statement also recommends against the use of beta-carotene (increases risk of CVD mortality and lung cancer) or vitamin E (clear evidence of no benefit)

USPSTF Statement: Insufficient evidence to recommend Vitamin D deficiency screening

Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases

Systematic Review: Low‐carbohydrate vs. balanced‐carbohydrate diets for reducing weight and cardiovascular risk.

30 Jan, 2022 | 14:28h | UTC

Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk – Cochrane Library

Summary: Low-carbohydrate diets or balanced-carbohydrate diets: which works better for weight loss and heart disease risks? – Cochrane Library

Commentary: Featured review: Low-carbohydrate versus balanced-carbohydrate diets for reducing weight and cardiovascular risk – Cochrane Library

Commentary on Twitter

https://twitter.com/CochraneUK/status/1487879806100414474

Guideline Summary: Management of the top 10 most common immune-related adverse events in patients treated with immune checkpoint inhibitor therapy.

30 Jan, 2022 | 14:11h | UTC

Management of the Top 10 Most Common Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy – JCO Oncology Practice

Original Article: ASCO Guideline Update: Management of immune-related adverse events in patients treated with immune checkpoint inhibitor therapy.

Clinical practice guideline on immune checkpoint inhibitor-related adverse events.

NCCN Guidelines Insights: Management of Immunotherapy-Related Toxicities (several resources on the subject)

M-A: SGLT-2 inhibitors and cardiovascular outcomes in patients with and without a history of heart failure.

30 Jan, 2022 | 13:56h | UTC

SGLT-2 inhibitors and cardiovascular outcomes in patients with and without a history of heart failure: a systematic review and meta-analysis – European Heart Journal – Cardiovascular Pharmacotherapy

Commentary on Twitter

SGLT-2 inhibitors improve CV outcomes irrespective of heart failure history and LVEF: a meta-analysis of RCTs https://t.co/QPRCzT9olH #EHJPharmacotherapy #cardiotwitter @AgewallStefan @GianluSava pic.twitter.com/sESFn7Fdxg

— European Society of Cardiology Journals (@ESC_Journals) January 29, 2022

Casualties of COVID: Insulin and Dialysis – “How the pandemic has been life-threatening to people living with diabetes and chronic kidney disease”.

28 Jan, 2022 | 08:28h | UTC

Casualties of COVID: Insulin and Dialysis - Think Global Health

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