Editor's Choice
RT | Routine early arthroscopic partial meniscectomy is not superior to physical therapy for traumatic meniscal tears.
25 Nov, 2022 | 12:38h | UTC
Commentary on Twitter
⚠️ Traumatic meniscal tears 🦵
✨Arthroscopic partial meniscectomy vs physical therapy✨
Which management is more optimal for improving symptoms, knee function and ability to participate in sports ⁉️🤔
NEW #OpenAccess Original Research 📄
➡️ https://t.co/Z0FSuRboj7 pic.twitter.com/aBgjcxfCav
— British Journal of Sports Medicine (BJSM) (@BJSM_BMJ) June 15, 2022
BMJ Investigation | FDA oversight of clinical trials is “grossly inadequate,” say experts.
25 Nov, 2022 | 12:35h | UTCFDA oversight of clinical trials is “grossly inadequate,” say experts – The BMJ
News Release: Investigation raises concerns about poor FDA oversight of clinical trials – BMJ Newsroom
Commentary: FDA Oversight of Clinical Trials Described as ‘Grossly Inadequate’ – HealthDay
WHO report highlights oral health neglect affecting nearly half of the world’s population.
24 Nov, 2022 | 13:36h | UTCNews Release: WHO highlights oral health neglect affecting nearly half of the world’s population – World Health Organization
Commentary: Oral Health Neglect: The Overlooked Crisis Affecting 3.5 Billion People – Health Policy Watch
Commentary on Twitter (thread – click for more)
Good #OralHealth is essential in our daily lives helping us eat, breathe, and speak.
Yet, oral diseases affect nearly 3.5 billion people worldwide. More in WHO’s new Global Oral Health Status Report 👉https://t.co/NYOvKYy6Xg pic.twitter.com/zpyI2uqWfT
— World Health Organization (WHO) (@WHO) November 18, 2022
WHO updates recommendations to guide family planning decisions.
24 Nov, 2022 | 13:38h | UTCNews Release: WHO updates recommendations to guide family planning decisions – World Health Organization
Family planning: A global handbook for providers – World Health Organization (PDF)
Commentary on Twitter (thread – click for more)
👉WHO releases important updates to its Family Planning Handbook 🔖
⏭providing health workers and policymakers with the most updated information on contraceptive options.
Know more:🔗https://t.co/UhC1BFca2r pic.twitter.com/LQEtm3wmbZ
— World Health Organization (WHO) (@WHO) November 15, 2022
RCT | Anticoagulation for 3 months reduces recurrence rates vs. treatment for 6 weeks in patients with isolated distal DVT.
24 Nov, 2022 | 13:34h | UTCNews Release: Extending anti-clotting treatment after distal DVT reduces further clot risk – BMJ Newsroom
Review | Climate change and vectorborne diseases.
24 Nov, 2022 | 13:31h | UTCClimate Change and Vectorborne Diseases – New England Journal of Medicine
Commentary on Twitter
Warming temperatures and changes in precipitation associated with climate change are affecting the occurrence of vectorborne diseases. Effective, equitable strategies are needed for vector control and disease management. https://t.co/o1yUTkjs93 pic.twitter.com/4Qn4RRXBcL
— NEJM (@NEJM) November 23, 2022
Review | Psychiatric issues among health professionals.
24 Nov, 2022 | 13:29h | UTCPsychiatric Issues Among Health Professionals – Medical Clinics of North America
Review | Care of the seriously ill patient with SARS-CoV-2.
24 Nov, 2022 | 13:26h | UTCCare of the Seriously Ill Patient with SARS-CoV-2 – Medical Clinics of North America
RCT | Low-dose morphine did not significantly reduce the intensity of chronic breathlessness in patients with COPD.
23 Nov, 2022 | 14:09h | UTCEffect of Regular, Low-Dose, Extended-release Morphine on Chronic Breathlessness in Chronic Obstructive Pulmonary Disease: The BEAMS Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Dyspnea—When a Sensation Becomes a Symptom – JAMA (free for a limited period)
See also: Visual Abstract
Commentary: Breathlessness in Patients with COPD isn’t Reduced with Daily Morphine – HCP Live
KDIGO 2022 Guideline for the prevention, diagnosis, evaluation, and treatment of Hepatitis C in chronic kidney disease.
23 Nov, 2022 | 14:11h | UTCExecutive Summary: KDIGO 2022 Clinical Practice Guideline for the Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C in Chronic Kidney Disease – Kidney International
Guideline Synopsis | Diagnosis and treatment of infertility in men.
23 Nov, 2022 | 14:08h | UTCDiagnosis and Treatment of Infertility in Men – JAMA (free for a limited period)
Original Guideline: AUA/ASRM Guideline: Diagnosis and treatment of infertility in men
RCT | Treatment of early Lyme Disease with doxycycline for 7 days is noninferior to treatment for 14 days.
23 Nov, 2022 | 14:06h | UTCTreatment of erythema migrans with doxycycline for 7 days versus 14 days in Slovenia: a randomised open-label non-inferiority trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Commentary: Shorter Duration of Antibiotics Noninferior for Lyme Disease – JAMA (free for a limited period)
Commentary on Twitter
New research: Treatment of erythema migrans with doxycycline for 7 days versus 14 days in Slovenia: a randomised open-label non-inferiority trialhttps://t.co/8lktc4gxzG pic.twitter.com/mP2e0Kn7C5
— The Lancet Infectious Diseases (@TheLancetInfDis) October 7, 2022
RCT | Impact of empagliflozin on decongestion in acute heart failure.
23 Nov, 2022 | 14:04h | UTCCommentary: Empagliflozin in Patients Hospitalized for Acute Heart Failure – EMPULSE – American College of Cardiology
Commentary on Twitter
What's the impact of empagliflozin on decongestion in acute heart failure? New insights from the EMPULSE trial in EHJ!https://t.co/O1MZTFPWCc#SGLT2 #decongestion #heartfailure #empagliflozin #cardiotwitter @escardio @ESC_Journals pic.twitter.com/QLJYNgl1Zo
— EHJ Editor-in-Chief (@ehj_ed) October 19, 2022
Under a https://creativecommons.org/licenses/by-nc/4.0/ license
Cohort Study | Race-dependent association of HDL-C levels with incident coronary artery disease.
23 Nov, 2022 | 14:02h | UTCNews Release: Study challenges “good” cholesterol’s role in universally predicting heart disease risk – National Institutes of Health
RCT | Effects of a physical exercise intervention during vs. after chemotherapy to improve cardiorespiratory fitness.
23 Nov, 2022 | 14:01h | UTCEditorial: Inclusion of Exercise in Cancer Treatment Planning: When Is the Right Time? – JACC: CardioOncology
Commentary: Exercise Intervention During Chemotherapy Beneficial – HealthDay
SR | Blood pressure targets for the treatment of people with hypertension and cardiovascular disease.
22 Nov, 2022 | 13:39h | UTCSummary: Blood pressure targets in people with cardiovascular disease – Cochrane Library
Commentary on Twitter
https://twitter.com/CochraneUK/status/1594059435202289666
M-A | Use of CT of the head in patients with acute atraumatic altered mental status.
22 Nov, 2022 | 13:38h | UTC
Commentary on Twitter
Meta-analysis: 94% of patients with atraumatic altered mental status received a noncontrast CT head, with an average yield of 11% which varied by setting: 18% in ED patients, 12% of ICU patients, and 3% of general inpatients had positive findings on CT. https://t.co/yHWj6uSwTM
— JAMA Network Open (@JAMANetworkOpen) November 18, 2022
M-A | Balloon catheters vs. vaginal prostaglandins for labor induction.
22 Nov, 2022 | 13:35h | UTCBalloon catheters versus vaginal prostaglandins for labour induction (CPI Collaborative): an individual participant data meta-analysis of randomised controlled trials – The Lancet (link to abstract – $ for full-text)
Commentary: Balloon labor induction safer for babies, researchers find – Monash University
Commentary on Twitter (thread – click for more)
https://twitter.com/TheLancet/status/1592460860026679296
Guardianship | A medicolegal review for clinicians.
22 Nov, 2022 | 13:33h | UTCGuardianship: A medicolegal review for clinicians – Journal of the American Geriatrics Society
RCT | Intermittently scanned continuous glucose monitoring vs. fingerstick testing for Type 1 DM.
21 Nov, 2022 | 14:45h | UTCRCT | Intermittently scanned continuous glucose monitoring vs. fingerstick testing for Type 1 DM.
Intermittently Scanned Continuous Glucose Monitoring for Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Continuous Monitoring Outperforms Fingerstick Testing in Patients With T1D, High Glycated Hemoglobin – AJMC
Commentary on Twitter
In persons with type 1 diabetes, intermittently scanned continuous glucose monitoring led to significantly lower glycated hemoglobin levels than participant monitoring with fingerstick testing. https://t.co/2JkNKDyoQJ pic.twitter.com/CXEcARsLD8
— NEJM (@NEJM) October 5, 2022
RCT | The effects of modifying amount and type of dietary carbohydrate on esophageal reflux symptoms.
21 Nov, 2022 | 14:42h | UTCCommentary: Study finds that reducing intake of simple sugars improves GERD – Vanderbilt University
RCT | NIV is superior to high-flow nasal cannula to prevent reintubation in patients at high risk for extubation failure.
21 Nov, 2022 | 14:41h | UTCEffect of postextubation noninvasive ventilation with active humidification vs high-flow nasal cannula on reintubation in patients at very high risk for extubation failure: a randomized trial – Intensive Care Medicine (free for a limited period)
Commentary on Twitter
NIV + active humidification vs HFNC in adult critically ill pts at very high-risk for extubation failure, RCT in 🇪🇸 ICUs: noninvasive ventilation superior to high-flow nasal cannula O2
➡️ reintubation required in 23.3% pts receiving NIV vs 38.8% if HFNC
📎 https://t.co/2mNTf3PYEF pic.twitter.com/Fp2GtZpcLx— Intensive Care Medicine (@yourICM) November 19, 2022
Cluster RCT | A personalized cooler dialysate provides no benefit for patients receiving maintenance hemodialysis.
21 Nov, 2022 | 14:38h | UTCPersonalised cooler dialysate for patients receiving maintenance haemodialysis (MyTEMP): a pragmatic, cluster-randomised trial – The Lancet (link to abstract – $ for full-text)
Commentary: Clinical trial examines optimal dialysis temperature – University of Western Ontario
Commentary on Twitter (thread – click for more)
Over 2 million people worldwide with #kidneyfailure rely on maintenance #dialysis treatments.
Trial, MyTEMP, assesses the effects of cooler dialysate compared with standard temperature in individuals receiving outpatient maintenance dialysis.🧵 pic.twitter.com/M9JscDqM2v
— The Lancet (@TheLancet) November 17, 2022
M-A | Global monkeypox case hospitalization rates.
21 Nov, 2022 | 14:36h | UTCRelated:
Monkeypox – New England Journal of Medicine
Monkeypox: disease epidemiology, host immunity and clinical interventions.
Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health
CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.
Update on the Monkeypox Outbreak – JAMA
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks: a global case series.
21 Nov, 2022 | 14:35h | UTCCommentaries:
Study describes monkeypox in women; CDC warns of Tpoxx resistance – CIDRAP
Related:
Monkeypox – New England Journal of Medicine
Monkeypox: disease epidemiology, host immunity and clinical interventions.
Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health
CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.
Update on the Monkeypox Outbreak – JAMA
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases