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2ry analysis of a RCT | Vitamin D supplementation did not influence growth, body composition, and pubertal development in children.

30 Nov, 2022 | 13:49h | UTC

Influence of Vitamin D Supplementation on Growth, Body Composition, and Pubertal Development Among School-aged Children in an Area With a High Prevalence of Vitamin D Deficiency: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)

Commentary: Vitamin D Supplementation Does Not Influence Growth in Children – HealthDay

 

Survey | Imposter syndrome in US physicians relative to the US working population.

30 Nov, 2022 | 13:43h | UTC

Imposter Phenomenon in US Physicians Relative to the US Working Population – Mayo Clinic Proceedings

Editorial: The Imposter Syndrome in Physicians – Mayo Clinic Proceedings

 

Commentary from the author on Twitter

 

ACP Guidance | Outpatient treatment of confirmed COVID-19.

30 Nov, 2022 | 13:54h | UTC

Outpatient Treatment of Confirmed COVID-19: Living, Rapid Practice Points From the American College of Physicians (Version 1) – Annals of Internal Medicine

Editorial: Ongoing Need for Clinical Trials and Contemporary End Points for Outpatient COVID-19 – Annals of Internal Medicine

Commentary: New ACP living practice points, mortality data on COVID-19 – ACP Internist

 

Cohort Study | Acute and postacute sequelae associated with SARS-CoV-2 reinfection.

30 Nov, 2022 | 13:42h | UTC

Acute and postacute sequelae associated with SARS-CoV-2 reinfection – Nature Medicine

News Release: Repeat COVID-19 infections increase risk of organ failure, death – Washington University School of Medicine

Commentary: SARS-CoV-2 Reinfection Ups Risks for Death, Hospitalization – HealthDay

 

RCT | Effect of irrigation fluid temperature on recurrence in the evacuation of chronic subdural hematoma.

30 Nov, 2022 | 13:45h | UTC

Effect of Irrigation Fluid Temperature on Recurrence in the Evacuation of Chronic Subdural Hematoma – JAMA Neurology

News Release: Warmer brain-irrigation fluid in surgery more efficacious – University of Gothenburg 

 

Commentary on Twitter

 

WHO renames “monkeypox” as “mpox” to help destigmatize the disease.

29 Nov, 2022 | 14:27h | UTC

WHO recommends new name for monkeypox disease – World Health Organization

Commentaries:

WHO to phase out the name ‘monkeypox’ for ‘mpox’ – STAT

WHO renames monkeypox as mpox, citing racist stigma – NPR

The Future of Monkeypox – The Atlantic

Monkeypox given new name by global health experts – BBC

Monkeypox to be renamed mpox to avoid stigma, says WHO – The Guardian

 

Commentary on Twitter (thread – click for more)

 

WHO Global tuberculosis report 2022.

29 Nov, 2022 | 14:25h | UTC

Global tuberculosis report 2022 – World Health Organization

News Release: Tuberculosis deaths and disease increase during the COVID-19 pandemic – World Health Organization

Video Summary: WHO Global Tuberculosis Report 2022: Key findings and messages – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

M-A | Thiazide diuretics and fracture risk.

29 Nov, 2022 | 14:23h | UTC

Thiazide Diuretics and Fracture Risk: A Systematic Review and Meta-Analysis of Randomized Clinical Trials – JBMR Plus

 

Study shows Omicron sublineage BQ.1.1 is resistant to all monoclonal antibodies.

29 Nov, 2022 | 14:16h | UTC

Omicron sublineage BQ.1.1 resistance to monoclonal antibodies – The Lancet Infectious Diseases

Commentaries: 

New Omicron subvariant BQ.1.1 resistant to all therapeutic antibodies, study finds – Deutsches Primatenzentrum (DPZ)/German Primate Center

Omicron variant BQ.1.1 found to be resistant to all monoclonal antibody treatments – MedicalXpress

Related: BQ.1 and BQ.1.1 are now the dominant COVID variants. What does that mean? – MedicalXpress

 

Commentary on Twitter

 

Opinion | Minimizing administrative harm: a key step to improving health care.

29 Nov, 2022 | 14:21h | UTC

Minimizing administrative harm: a key step to improving health care – STAT

 

Perspective | Eight billion and counting.

29 Nov, 2022 | 14:19h | UTC

Eight Billion and Counting – Think Global Health

 

Cohort Study | Impact of the trimester of diagnosis on COVID-19 disease progression in pregnancy.

29 Nov, 2022 | 14:18h | UTC

Examining the impact of trimester of diagnosis on COVID-19 disease progression in pregnancy – American Journal of Obstetrics & Gynecology MFM (free for a limited period)

News Release: Risk of severe COVID-19 symptoms remains throughout pregnancy, study finds – UT Southwestern Medical Center

 

Commentary on Twitter

 

2023 GOLD Report | Global strategy for prevention, diagnosis and management of COPD.

27 Nov, 2022 | 22:32h | UTC

2023 GOLD REPORT: global strategy for prevention, diagnosis and management of COPD: 2023 Report – Global Initiative for Chronic Obstructive Lung Disease

 

WHO recommendations for care of the preterm or low-birth-weight infant.

27 Nov, 2022 | 22:31h | UTC

WHO recommendations for care of the preterm or low-birth-weight infant – World Health Organization

News Release: Launch of the WHO recommendations for care of the preterm or low birth weight infant – World Health Organization

Commentary: Skin to Skin Contact between Mothers and Preterm, Underweight Babies Improve Chances of Survival, says WHO – Health Policy Watch

 

Commentary on Twitter (thread – click for more)

 

Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019.

27 Nov, 2022 | 22:30h | UTC

Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019 – The Lancet

News Release: One in eight deaths in 2019 linked to bacterial infections, the second leading cause of death globally – Institute for Health Metrics and Evaluation

Commentary: Report highlights the deadly impact of bacterial infections – CIDRAP

 

Commentary on Twitter (thread – click for more)

 

Seminar | Monkeypox.

27 Nov, 2022 | 22:29h | UTC

Monkeypox – The Lancet

Commentaries:

Study shows there is substantial monkeypox transmission before symptoms appear.

Global monkeypox case hospitalisation rates: A rapid systematic review and meta-analysis – eClinicalMedicine 

Human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks: a global case series – The Lancet 

Monkeypox — A Sobering Sentinel for Pandemic Preparedness and Sexual Health System Capacity – New England Journal of Medicine 

CDC study shows healthcare workers have a low risk of infection after exposure to patients with monkeypox. 

Monkeypox – New England Journal of Medicine 

Diagnosis and Management of Monkeypox: A Review for the Emergency Clinician – Annals of Emergency Medicine 

Monkeypox: disease epidemiology, host immunity and clinical interventions. 

Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health 

Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain. 

CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US. 

Update on the Monkeypox Outbreak – JAMA 

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases 

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ 

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch 

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine 

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases 

 

Commentary on Twitter

 

RCT | Rectal culture-based vs. empirical antibiotic prophylaxis to prevent infections in men undergoing transrectal prostate biopsy.

27 Nov, 2022 | 22:28h | UTC

Rectal culture-based versus empirical antibiotic prophylaxis to prevent infectious complications in men undergoing transrectal prostate biopsy: a randomized, non-blinded multicenter trial – Clinical Infectious Diseases (link to abstract – $ for full-text)

 

Commentary on Twitter

 

SR | E-cigarettes are more effective than traditional nicotine-replacement methods in helping people quit smoking.

27 Nov, 2022 | 22:26h | UTC

Electronic cigarettes for smoking cessation – Cochrane Library

News Release: E-cigarettes are more effective than nicotine-replacement therapy in helping smokers quit – University of Oxford

Commentaries: 

Latest Cochrane Review finds high certainty evidence that nicotine e-cigarettes are more effective than traditional nicotine-replacement therapy (NRT) in helping people quit smoking – Cochrane Library

Expert reaction to Cochrane review on electronic cigarettes for smoking cessation – Science Media Centre

 

Commentary on Twitter

 

Improving antimicrobial stewardship with penicillin allergy testing: a review of current practices and unmet needs.

27 Nov, 2022 | 22:25h | UTC

Improving antimicrobial stewardship with penicillin allergy testing: a review of current practices and unmet needs – JAC-Antimicrobial Resistance

Related:

Management of Patients with Suspected or Confirmed Antibiotic Allergy. Executive Summary of Guidance from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Society of Allergy and Clinical Immunology (SEAIC), the Spanish Society of Hospital Pharmacy (SEFH) and the Spanish Society of Intensive Medicine and Coronary Care Units (SEMICYUC) – Journal of Investigational Allergology and Clinical Immunology (PDF)

The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.

The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.

M-A: Most patients with allergy to Penicillin can be given Cefazolin

Systematic review: Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge

Penicillin allergy labels increase second-line broad-spectrum antibiotic prescribing for pediatric respiratory tract infections

Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy

Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule

Management of a surgical patient with a label of penicillin allergy: narrative review and consensus recommendations – British Journal of Anaesthesia

NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk

Cohort Study: Risk of Meticillin Resistant Staphylococcus Aureus and Clostridium Difficile in Patients with a Documented Penicillin Allergy

 

M-A | Cardioprotective effects of influenza vaccination in patients with high risk of cardiovascular disease.

25 Nov, 2022 | 12:47h | UTC

Cardioprotective effects of influenza vaccination among patients with established cardiovascular disease or at high cardiovascular risk: a systematic review and meta-analysis – European Journal of Preventive Cardiology (free for a limited period)

Related:

RCT | Influenza vaccine to reduce adverse vascular events in patients with heart failure.

RCT | A double-dose influenza vaccination during hospitalization for acute coronary syndrome did not improve outcomes compared to standard-dose outpatient vaccination.

 

2ry analysis of a RCT | Decongestion with acetazolamide in acute heart failure across the spectrum of left ventricular EF.

25 Nov, 2022 | 12:45h | UTC

Decongestion with Acetazolamide in Acute Decompensated Heart Failure across the Spectrum of Left Ventricular Ejection Fraction: a Pre-specified Analysis from the ADVOR trial – Circulation

Original Study: RCT | Acetazolamide resulted in faster decongestion in patients with acute decompensated heart failure with volume overload.

 

Commentary on Twitter

 

Study shows there is substantial monkeypox transmission before symptoms appear.

25 Nov, 2022 | 12:43h | UTC

Transmission dynamics of monkeypox in the United Kingdom: contact tracing study – The BMJ

Editorial: The dynamics of monkeypox transmission – The BMJ

News Release: Evidence for “substantial” monkeypox transmission before symptoms – BMJ Newsroom

Commentaries:

Expert reaction to study looking at monkeypox transmission before symptoms appear – Science Media Centre

Study finds evidence of ‘considerable’ presymptomatic spread of monkeypox – The Guardian

 

RCT | Vitamin D fails to prevent statin-associated muscle symptoms among new statin users.

25 Nov, 2022 | 12:40h | UTC

Statin-Associated Muscle Symptoms Among New Statin Users Randomly Assigned to Vitamin D or Placebo – JAMA Cardiology (free for a limited period)

Commentary: Vitamin D fails to reduce statin-associated muscle pain – Northwestern University

 

Commentary on Twitter

 

Case–control study | GLP-1 receptor agonists linked to increased risk of thyroid cancer.

25 Nov, 2022 | 12:42h | UTC

GLP-1 Receptor Agonists and the Risk of Thyroid Cancer – Diabetes Care (link to abstract – $ for full-text)

Commentary: GLP-1 receptor agonists associated with thyroid cancer – ACP Internist

 

SR | Strategies to prevent and manage running-related knee injuries.

25 Nov, 2022 | 12:37h | UTC

Strategies to prevent and manage running-related knee injuries: a systematic review of randomised controlled trials – British Journal of Sports Medicine (link to abstract – $ for full-text)

Commentaries:

How can we prevent and manage running-related knee injuries? – BJSM Blog

Changes in technique, footwear and intervention prevent running-related knee injuries – Physician’s weekly

 

Commentary from the author on Twitter

 

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