Critical Care & Emergencies (all articles)
Covid-19: Risk of death more than doubled in people who also had flu, English data show
7 Oct, 2020 | 09:11h | UTCCovid-19: Risk of death more than doubled in people who also had flu, English data show – The BMJ
Original study (preprint): Interactions between SARS-CoV-2 and Influenza and the impact of coinfection on disease severity: A test negative design – medRxiv
Commentary on Twitter
People infected with both flu and SARS-CoV-2 are more than twice as likely to die as someone with the new coronavirus alone, emerging evidence analysed by @PHE_uk has found. The data has been published as a preprint on medRxivhttps://t.co/3Qv3gxGRXB
— The BMJ (@bmj_latest) September 23, 2020
Randomized trial: Tranexamic acid during prehospital transport in patients at risk for hemorrhage after injury
7 Oct, 2020 | 09:04h | UTCCommentaries: Prehospital Tranexamic Acid: STAAMP of Approval or Return to Sender? – JAMA Surgery AND Trial examines prehospital administration of blood-clotting agent in severely injured trauma patients – News Medical
Commentary on Twitter
TXA as an adjunct to prehospital #injury management seems to improve #outcome but only in specific subgroups. A nicely done multicenter trial that raises more questions to be answered. @SCCM @JAMASurgery https://t.co/rTQz8qJO0o
— Lewis J. Kaplan (@SCCMPresident) October 5, 2020
Systematic Review: Thoracic imaging tests for the diagnosis of COVID‐19
7 Oct, 2020 | 09:07h | UTCThoracic imaging tests for the diagnosis of COVID‐19 – Cochrane Library
Commentaries: How accurate is chest imaging for diagnosing COVID-19? – Cochrane Library AND Featured Review: Thoracic imaging tests for the diagnosis of COVID-19 – Cochrane Library
Systematic review: Complications of cricothyroidotomy versus tracheostomy in emergency surgical airway management
7 Oct, 2020 | 08:52h | UTC
Long-term health consequences of COVID-19
6 Oct, 2020 | 00:58h | UTCLong-term Health Consequences of COVID-19 – JAMA
Commentary on Twitter
Persistent post-COVID symptoms could be the from direct tissue invasion by the virus, profound inflammation & cytokine storm, related immune system damage, hypercoagulable state, or some combination https://t.co/G8tI9U3TaL @CarlosdelRio7 lfcollins_md @PreetiNMalani
— JAMA (@JAMA_current) October 5, 2020
Meta-analysis: Risk of venous thromboembolism in patients with COVID‐19
6 Oct, 2020 | 00:54h | UTC
Commentaries on Twitter
In a new #RPTH paper, researchers performed a meta-analysis of #VTE risk in #COVID19 patients: 22.7% prevalence in ICU vs. 7.9% in non-ICU patients. Other subgroup analyses reveal heterogeneity and interesting trends…@Cihan_Ay_MD @FlorianMoik NEW: https://t.co/24IWOm5qTe pic.twitter.com/HjnSYq9YKz
— RPTH (@RPTHjournal) September 30, 2020
Meta-analysis of #clotting events in 66 studies including 28173 patients with #COVID19. High #VTE & #PE prevalence in ICU patients indicates a need for thromboprophylaxis research! Read the results at #RPTH by @Cihan_Ay_MD @FlorianMoik https://t.co/24IWOlNPuE @thrombosisday pic.twitter.com/V4Pn2ssBH3
— RPTH (@RPTHjournal) October 5, 2020
What we have found was a trend of decreased VTE rates over time. Earlier studies reported slightly higher VTE rates than more recent ones. What could be the reason? Experience dealing with COVID19 and improved preventive strategies? https://t.co/YDjRyvNmK6 https://t.co/y3Uj5x3QRI pic.twitter.com/0HcFQvMJB8
— Cihan Ay (@Cihan_Ay_MD) September 26, 2020
Case series of multisystem inflammatory syndrome in adults associated with SARS-CoV-2 infection
4 Oct, 2020 | 23:36h | UTCCommentary: Mysterious inflammatory syndrome tied to COVID-19 strikes adults as well as kids – Live Science
Commentary on Twitter
A new @CDCMMWR finds that adults who had #COVID19 can develop a condition similar to multisystem inflammatory syndrome in children and have severe outcomes including requiring intensive care. Learn more: https://t.co/dU1tS85Sj3. pic.twitter.com/RitCzJsLTL
— CDC (@CDCgov) October 2, 2020
Perspective: What we know about vitamin D and Covid-19 (spoiler: not much)
4 Oct, 2020 | 23:28h | UTCWhat We Know About Vitamin D and Covid-19 – Medium
Editorial: COVID ARDS is not different from ARDS of other causes. Patients should be managed according to the evidence-based recommendations for non COVID related ARDS.
4 Oct, 2020 | 23:23h | UTC
Commentary on Twitter
#COVID19 #ARDS? after careful bedside physiological assessment, we may state #SARSCoV2 pts may be managed according to evidence-based recommendations for non COVID related ARDS@audreydejongMD @oriolrocag https://t.co/71TqeTJXMW
On @cafeoranestesia et al https://t.co/FZS2oGm30D pic.twitter.com/HJQ4FLCuL2
— Intens Care Med (@yourICM) October 3, 2020
Evaluation of oxygenation in 129 proning sessions in 34 mechanically ventilated COVID-19 patients
4 Oct, 2020 | 23:24h | UTC
ASH 2020 guidelines for the management of deep vein thrombosis and pulmonary embolism
4 Oct, 2020 | 23:12h | UTC
Cohort study: In-hospital cardiac arrest in critically ill patients with Covid-19
2 Oct, 2020 | 09:24h | UTCCommentary: Cardiac arrest, poor survival rates common in sickest patients with COVID-19 – University of Michigan
Related Study: Clinical Outcomes of In-Hospital Cardiac Arrest in COVID-19 – JAMA Internal Medicine
Commentaries on Twitter
Cardiac arrest with severe #COVID19, in-hospital:
relatively common, very poor outcome, especially w/ ⬆️age
Two series:
701 patients (14%)https://t.co/Pu0V15lemL @bmj_latest @salimhayek @umichmedicine @MHealthLab
60 patients (5%)https://t.co/Exwk68VXgg @JAMAInternalMed pic.twitter.com/9cwS0HlNxz— Eric Topol (@EricTopol) October 2, 2020
Cardiac arrest is common in critically ill patients with #COVID19 and is associated with poor survival, particularly among patients aged 80 or older, finds new research @salimhayek
https://t.co/O2Z2K3TAeT— The BMJ (@bmj_latest) October 1, 2020
Randomized trial: Hydroxychloroquine vs. placebo for pre-exposure SARS-CoV-2 prophylaxis among health care workers
1 Oct, 2020 | 09:17h | UTCCommentary: Hydroxychloroquine didn’t prevent COVID-19 among health care workers in new study – CNN
Commentary on Twitter
#Hydroxychloroquine taken daily by hospital-based health care providers over 8 weeks did not prevent #SARSCoV2 infection, in a double-blind randomized placebo-controlled trial performed at 2 University of Pennsylvania hospitals https://t.co/7XHn6uBh4Z
— JAMA Internal Medicine (@JAMAInternalMed) September 30, 2020
Recommendations for antibacterial therapy in adults with COVID-19 – An evidence based guideline
1 Oct, 2020 | 09:15h | UTC
Commentary on Twitter
?Just published?@CMIJournal
Recommendations for antibacterial therapy in adults with COVID-19 – An evidence based guideline by the Dutch Working Party on Antibiotic Policy. #IDTwitter #COVID19 https://t.co/7cfZtS6Duv pic.twitter.com/Kz7CPMNLmh— Antibiotic Steward? Bassam Ghanem (@ABsteward) September 30, 2020
Keeping best practices in critical care during COVID-19
1 Oct, 2020 | 09:08h | UTCKeeping Best Practices in Critical Care During COVID-19 – ICU Management & Practice
Commentary on Twitter
COVID-19 poses several challenges and has made it difficult to measure ICU performance.
Read the article 'Keeping Best Practices in Critical Care During COVID-19' by @f_g_zampieri ?https://t.co/kvwlGSLBav#Covid19 #ICU #patientoutcome #FOAMcc #FOAMed pic.twitter.com/2YOhOnidxZ
— ICU Management (@ICU_Management) September 28, 2020
Invasive candidiasis in critical care: Challenges and future directions
1 Oct, 2020 | 09:00h | UTCInvasive candidiasis in critical care: challenges and future directions – Intensive Care Medicine
Commentary on Twitter
Invasive candidiasis: most common #ICU fungal infection ~40-55% mortality. Key challenges:
➡️ changing epidemiology/emergence of resistances
➡️ timely/appropriate therapy initiation/discontinuation
➡️ choosing/tailoring optimal antifungals#FOAMcc review https://t.co/tMPNcYfzwL pic.twitter.com/HvJKr0jX2o— Intens Care Med (@yourICM) September 30, 2020
Systematic review: The effectiveness and cost‐effectiveness of hospital‐based specialist palliative care for adults with advanced illness and their caregivers
1 Oct, 2020 | 08:58h | UTC
Commentary on Twitter
Cochrane review on hospital-based specialist palliative care. Findings: Improved HR-QoL and patient satisfaction, reduced symptom burden and depression, and increased chances of patients dying in their preferred place. @SBajwah @cochranecollab https://t.co/wjhGp0gcbs
— Olaf Geerse (@OlafGeerse) September 30, 2020
New COVID-19 inpatient risk calculator estimates the probability of severe disease or death at hospital admission
30 Sep, 2020 | 09:51h | UTCCommentaries: COVID-19 ‘prediction model’ uses data that can help determine if patients’ conditions are likely to worsen – Johns Hopkins Medicine AND Prediction model incorporates more than 20 variables at hospital admission – Physician’s Weekly AND Patient Trajectories Among COVID-19 Hospitalized Patients – American College of Cardiology
Interactive Calculator: The COVID Inpatient Risk Calculator: CIRC
Commentary on Twitter
Lead authors Brian T. Garibaldi, MD, MEHP and Jacob Fiksel, PhD of @HopkinsMedicine developed the COVID-19 Inpatient Risk Calculator (CIRC) that uses patient data at admission to determine potential disease trajectory for #COVID19.
Link: https://t.co/i1e1ek7wO7. @Bedsidemedicine pic.twitter.com/wQLctHHYrn
— Annals of Int Med (@AnnalsofIM) September 22, 2020
Proposed clinical criteria for COVID-19-associated hyperinflammatory syndrome
30 Sep, 2020 | 09:50h | UTC
Commentary on Twitter
Defining and grading the clinical hyperinflammatory syndrome with #COVID19 and how this cytokine storm relates to outcomes https://t.co/6Ngp3OHZJx @TheLancetRheum @Intermountain pic.twitter.com/bDGwKpjOI4
— Eric Topol (@EricTopol) September 29, 2020
Intensive care unit acquired muscle weakness in COVID-19 patients
30 Sep, 2020 | 09:39h | UTCIntensive care unit acquired muscle weakness in COVID-19 patients – Intensive Care Medicine
Commentary on Twitter
#ICU acquired muscle weakness in #COVID19 frequently occurring in critically ills on prolonged sedation. Price to pay for rigorous protective MV? follow-up essential to offer tailored rehab, trying to reduce long-term impact on functional status. #ICUrehab https://t.co/anf0WE0W4w pic.twitter.com/MdnNzYuTN8
— Intens Care Med (@yourICM) September 28, 2020
Editorial – Stress ulcer prophylaxis: Is mortality a useful endpoint?
30 Sep, 2020 | 09:31h | UTCStress ulcer prophylaxis: Is mortality a useful endpoint? – Intensive Care Medicine
Commentary on Twitter
Stress ulcer prophylaxis: restrict to highest GI bleeding risk #ICU pts; still uncertainties on harmful effects (ie PK interactions?). Early EN, effective if low-risk + reducing underfeeding, to be encouraged. https://t.co/2EOsefikFc
Referring Wang et al https://t.co/MXnfHYyoJ4 pic.twitter.com/Xz8wmTzn62
— Intens Care Med (@yourICM) September 29, 2020
IDSA updated guidelines on the treatment of patients with COVID-19
28 Sep, 2020 | 01:40h | UTC
Commentary on Twitter
.@IDSAInfo has updated its #COVID19 treatment guidelines:
*Don't give #tocilizumab
*Give #dexamethasone but not if room air oxygen saturation is > 94%https://t.co/66nwQQZgsz pic.twitter.com/PQNAaFBZS4— Mike Stevens (@Dr_Mike_Stevens) September 26, 2020
ECMO in Covid-19: An international cohort
28 Sep, 2020 | 01:33h | UTC
Gastrointestinal complications in critically ill patients with and without COVID-19
25 Sep, 2020 | 02:44h | UTCGastrointestinal Complications in Critically Ill Patients With and Without COVID-19 – JAMA
Commentary on Twitter
#Covid patients have higher incidence of GI complications incl. mesenteric ischemia than propensity score-matched patients without #Covid. Check out our research letter @JAMA_current https://t.co/9RhC4t3JQ5 @ElmohebM @leon_naar @mathiasac @CarolijnKapoen @MahaFarhat @hayfarani
— Lydia Maurer (@LMaurerMD) September 24, 2020
Small randomized trial evaluated intravenous methylprednisolone pulse as a treatment for hospitalized severe COVID-19 patients
25 Sep, 2020 | 02:41h | UTC