Critical Care & Emergencies (all articles)
Proposed clinical criteria for COVID-19-associated hyperinflammatory syndrome
30 Sep, 2020 | 09:50h | UTC
Commentary on Twitter
Defining and grading the clinical hyperinflammatory syndrome with #COVID19 and how this cytokine storm relates to outcomes https://t.co/6Ngp3OHZJx @TheLancetRheum @Intermountain pic.twitter.com/bDGwKpjOI4
— Eric Topol (@EricTopol) September 29, 2020
Intensive care unit acquired muscle weakness in COVID-19 patients
30 Sep, 2020 | 09:39h | UTCIntensive care unit acquired muscle weakness in COVID-19 patients – Intensive Care Medicine
Commentary on Twitter
#ICU acquired muscle weakness in #COVID19 frequently occurring in critically ills on prolonged sedation. Price to pay for rigorous protective MV? follow-up essential to offer tailored rehab, trying to reduce long-term impact on functional status. #ICUrehab https://t.co/anf0WE0W4w pic.twitter.com/MdnNzYuTN8
— Intens Care Med (@yourICM) September 28, 2020
Editorial – Stress ulcer prophylaxis: Is mortality a useful endpoint?
30 Sep, 2020 | 09:31h | UTCStress ulcer prophylaxis: Is mortality a useful endpoint? – Intensive Care Medicine
Commentary on Twitter
Stress ulcer prophylaxis: restrict to highest GI bleeding risk #ICU pts; still uncertainties on harmful effects (ie PK interactions?). Early EN, effective if low-risk + reducing underfeeding, to be encouraged. https://t.co/2EOsefikFc
Referring Wang et al https://t.co/MXnfHYyoJ4 pic.twitter.com/Xz8wmTzn62
— Intens Care Med (@yourICM) September 29, 2020
IDSA updated guidelines on the treatment of patients with COVID-19
28 Sep, 2020 | 01:40h | UTC
Commentary on Twitter
.@IDSAInfo has updated its #COVID19 treatment guidelines:
*Don't give #tocilizumab
*Give #dexamethasone but not if room air oxygen saturation is > 94%https://t.co/66nwQQZgsz pic.twitter.com/PQNAaFBZS4— Mike Stevens (@Dr_Mike_Stevens) September 26, 2020
ECMO in Covid-19: An international cohort
28 Sep, 2020 | 01:33h | UTC
Gastrointestinal complications in critically ill patients with and without COVID-19
25 Sep, 2020 | 02:44h | UTCGastrointestinal Complications in Critically Ill Patients With and Without COVID-19 – JAMA
Commentary on Twitter
#Covid patients have higher incidence of GI complications incl. mesenteric ischemia than propensity score-matched patients without #Covid. Check out our research letter @JAMA_current https://t.co/9RhC4t3JQ5 @ElmohebM @leon_naar @mathiasac @CarolijnKapoen @MahaFarhat @hayfarani
— Lydia Maurer (@LMaurerMD) September 24, 2020
Small randomized trial evaluated intravenous methylprednisolone pulse as a treatment for hospitalized severe COVID-19 patients
25 Sep, 2020 | 02:41h | UTC
Understanding necrotizing soft tissue infections in the intensive care unit
25 Sep, 2020 | 02:31h | UTC
Commentary on Twitter
Necrotizing soft tissue infections in #ICU, focus on optimizing interventions most likely to impact outcome:
➡️ keep high index of suspicion vs misdiagnosis/delays in starting treatment
➡️ coordinate urgent approach: early debridement + broad-spectrum ABThttps://t.co/NpkxYFHbGl pic.twitter.com/8LDQuOGobI— Intens Care Med (@yourICM) September 22, 2020
JAMA Network Series: Medical Specialties and the COVID-19 Pandemic
24 Sep, 2020 | 09:45h | UTCEditorial: The COVID-19 Pandemic and the JAMA Network
See articles:
- Cardiology and COVID-19
- Dermatology and COVID-19
- Internal Medicine and COVID-19
- Nephrology and COVID-19
- Neurology and COVID-19
- Oncology and COVID-19
- Ophthalmology and COVID-19
- Otolaryngology–Head and Neck Surgery and COVID-19
- Pediatrics and COVID-19
- Psychiatry and COVID-19
- Surgery and COVID-19
- JAMA Network Open and COVID-19
- JAMA Health Forum and COVID-19
Association of red blood cell distribution width with mortality risk in hospitalized adults with SARS-CoV-2 infection
24 Sep, 2020 | 09:32h | UTCCommentary: Simple blood test can predict severity of COVID-19 for some patients – University of Texas Health Science Center at Houston AND Routine blood test may identify patients at risk for severe COVID-19 – UPI
Commentary on Twitter
Death in #COVID19: JAMA Open
In lots of dzs RDW >14.5% robustly risk stratifies pts w/in illness. True in #COVID! Mortality w/ nl RDW 11% vs. 31% with high RDW (9% ⬆️ risk per 0.5% increase in RDW). BEST predictor next to Age!https://t.co/aZJ3p488cN#medtwitter #tipsfornewdocs pic.twitter.com/967g2HElYH— WesElyMD (@WesElyMD) September 23, 2020
COVID-19 can affect the heart
24 Sep, 2020 | 09:30h | UTCCOVID-19 can affect the heart – Science
Commentary on Twitter
"These complications, which at times are the only features of #COVID19 clinical presentation, have occurred even in cases with mild symptoms and in people who did not experience any symptoms" https://t.co/q42cY3ujV4
a ?to explain 1/— Eric Topol (@EricTopol) September 24, 2020
Things we do for no reason: Routine correction of elevated INR and thrombocytopenia prior to paracentesis in patients with cirrhosis
24 Sep, 2020 | 09:17h | UTCSee collection: Choosing Wisely: Things We Do For No Reason – Journal of Hospital Medicine
Things we do for no reason: Routine coverage of anaerobes in aspiration pneumonia
24 Sep, 2020 | 09:17h | UTCSee collection: Choosing Wisely: Things We Do For No Reason – Journal of Hospital Medicine
[Preprint] Randomized trial: Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers
23 Sep, 2020 | 14:17h | UTC
Commentary on Twitter
? #Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: a randomized trial ?
-1st RCT on HCQ as PrEP
-1483 HCW randomized to HCQ 1x or 2x weekly or placebo
-No difference in development of confirmed or probable COVID19 https://t.co/Gn1otqKhrW pic.twitter.com/3r0HB56h9y
— Ilan Schwartz MD PhD (@GermHunterMD) September 21, 2020
COVID-19 clinical trials: Learning from exceptions in the research chaos
23 Sep, 2020 | 14:50h | UTCCOVID-19 clinical trials: learning from exceptions in the research chaos – Nature
Commentary on Twitter
Our analysis on #COVID clinical trials on Nature Medicine. Only big randomised trials can answer rapidly & reliably. Megatrials need support from regulators, funders, health services, docs. Pre-existing trial networks helpful. Collaboration key to success. https://t.co/YlalAEMR9r pic.twitter.com/wElfXfXdol
— Kari Tikkinen (@KariTikkinen) September 22, 2020
Cardiac arrhythmias in critically ill patients with COVID-19: A brief review
22 Sep, 2020 | 09:59h | UTC
Catheter-associated urinary tract infections in adults: diagnosis, treatment, and prevention
23 Sep, 2020 | 14:35h | UTCCatheter-Associated Urinary Tract Infections in Adults: Diagnosis, Treatment, and Prevention – Journal of Hospital Medicine (free for a limited period)
The core lesson of the COVID-19 heart debate
22 Sep, 2020 | 10:00h | UTCThe Core Lesson of the COVID-19 Heart Debate – The Atlantic
Commentary on Twitter
The Atlantic does a fantastic job in presenting balance. I'm happy I was able to contribute to this discussion about COVID and the heart in a small way. This is definitely worth the time to read #Covid #heart. https://t.co/gjtzZ7iRiy
— Paul Checchia (@ChecchiaPaul) September 21, 2020
Hospital COVID-19 risk lowest among intensive care staff
22 Sep, 2020 | 09:53h | UTCHospital COVID-19 risk lowest among intensive care staff – MedicalXpress
Original Study: SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study – Thorax
Commentary on Twitter
HOT OF THE PRESS@ThoraxBMJ#Covid19UK#NHS hospital staff
Asymptomatic viral carriage
2.4%Seroprevalence
▶️ Housekeeping 34.5%
▶️ Acute medicine 33.3%
▶️ General internal medicine 30.3%
▶️ Intensive care 14.8%#protectNHSstaff#protectNHSpatientshttps://t.co/iqBKl3qLYD— Prof. Nicholas Hart (@NickHartThorax) September 12, 2020
Ensuring adequate palliative and hospice care during COVID-19 surges
22 Sep, 2020 | 09:57h | UTCEnsuring Adequate Palliative and Hospice Care During COVID-19 Surges – JAMA
Commentary on Twitter
An ethical approach to #pandemic surge planning requires providing for patients seeking symptom relief & comfort at the end of life. Not to do so undermines patient, family trust, emotional health, and core values of society https://t.co/P0LeYuZwzt @MatthewWynia @CUPallCare
— JAMA (@JAMA_current) September 22, 2020
Editorial: How severe COVID-19 infection is changing ARDS management
22 Sep, 2020 | 09:37h | UTCHow severe COVID-19 infection is changing ARDS management – Intensive Care Medicine
Concise review: Management of acute ischemic stroke
22 Sep, 2020 | 09:26h | UTCManagement of Acute Ischemic Stroke – Critical Care Medicine
[Preprint] Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19: An international collaborative meta-analysis of randomized trials
20 Sep, 2020 | 21:42h | UTC
Commentary on Twitter
This meta-analysis of 7,913 patients from 26 RCTs (16 unpublished) found no mortality benefit to #hydroxychloroquine or chloroquine in COVID19
Combined summary OR for all-cause mortality for HCQ 1.08, 95%CI 0.99-1.18
Confirms HCQ does not help, may harmhttps://t.co/4o9bXkOo5Q pic.twitter.com/QG1XMzN0da
— Ilan Schwartz MD PhD (@GermHunterMD) September 19, 2020
Severe COVID-19 infections—knowledge gained and remaining questions
20 Sep, 2020 | 21:43h | UTCSevere COVID-19 Infections—Knowledge Gained and Remaining Questions – JAMA Internal Medicine
Commentary on Twitter
Just out @JAMAInternalMed – our editorial on what we've learned about severe #Covid19 pneumonia so far and what challenges are still ahead. Honored and proud to have written this together with Carolyn Calfee and Dan Brodie. https://t.co/rmVjUWNyvM
— Lieuwe Bos – Acute Pulmonary Medicine (@Acute_Pulmo_Med) September 18, 2020
Comparison of published guidelines for management of coagulopathy and thrombosis in critically ill patients with COVID 19
20 Sep, 2020 | 21:30h | UTC