Critical Care & Emergencies (all articles)
[Preprint] Exclusion of bacterial co-infection in COVID-19 using baseline inflammatory markers and their response to antibiotics
13 Oct, 2020 | 01:08h | UTC
Commentary on Twitter
Anyone think we prescribe too many #antibiotics in #COVID19?
Looking for ways to prescribe less?
Well, our latest *PREPRINT* (not peer reviewed!) may be of interest. #antibioticstewardship https://t.co/qUimnZhwg7 Thread (1/7) pic.twitter.com/Z6gaGMgduv— Gabriele Pollara (@gpollara) October 12, 2020
Meta-analysis: ECMO for severe ARDS
13 Oct, 2020 | 00:58h | UTC
Commentary on Twitter
#ECMO vs conventional strategies in severe #ARDS, meta-analysis of individual patient data:#ECMO-group pts spent more days alive out of the #ICU & without respiratory, cardiovascular, renal, neurological failure. Open access @yourICM #FOAMcc #FOAMecmo https://t.co/3PV2gAHA3G https://t.co/k6MQYUjKgu
— Intens Care Med (@yourICM) October 7, 2020
Review: Characteristics of SARS-CoV-2 and COVID-19
12 Oct, 2020 | 00:49h | UTCCharacteristics of SARS-CoV-2 and COVID-19 – Nature Reviews Microbiology
Commentary on Twitter
Characteristics of SARS-CoV-2 and COVID-19
Zheng-Li Shi et al. summarize the exceptional amount of research that has characterized SARS-CoV-2 and COVID-19, discussing the emergence and virology of SARS-CoV-2 and the pathogenesis and treatment of COVID-19https://t.co/kGL6nOdOYu pic.twitter.com/1ePqHvLxFz
— Nature Reviews Microbiology (@NatureRevMicro) October 6, 2020
Trends in clinical profiles, organ support use and outcomes of patients with cancer requiring unplanned ICU admission: a multicenter cohort study
12 Oct, 2020 | 00:31h | UTC
Commentary on Twitter
Read @f_g_zampieri et al: #ICU: a place for complex #oncology patients? outcomes of critically ills w cancer improved in past 8y
> 30% bed/days use
reduced mortality/ICU LOS
-> improved overall care?
Open #FOAMcc on @yourICM at https://t.co/lUKQsZvLcR#CCCF2020 @Dr_Cit https://t.co/8R8lDKEZal pic.twitter.com/VJ5XZLoVrA— Intens Care Med (@yourICM) October 7, 2020
Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
12 Oct, 2020 | 00:34h | UTC
Commentary on Twitter
DecubICUs study results: pressure injuries common in adult #ICU: 59.2% ICU-acquired, prevalence 16.2%.
Optimal care standards, increased awareness, proper resource allocation, focused research pivotal to tackle this main #ptsafety threat @StijnBLOT @ESICM https://t.co/gfJ9x06dnB pic.twitter.com/bUeOVwoVxk— Intens Care Med (@yourICM) October 9, 2020
Esophageal emergencies: Another important cause of acute chest pain
12 Oct, 2020 | 00:30h | UTCEsophageal emergencies: another important cause of acute chest pain – Insights into Imaging
RECOVERY trial: Effect of hydroxychloroquine in hospitalized patients with Covid-19
9 Oct, 2020 | 09:15h | UTC
Less is more: Critically ill status is not a carte blanche for unlimited antibiotic use
12 Oct, 2020 | 00:32h | UTC
Remdesivir for the treatment of Covid-19 — final report
9 Oct, 2020 | 09:13h | UTCRemdesivir for the Treatment of Covid-19 — Final Report – New England Journal of Medicine
Commentary: BREAKING NEWS: Final remdesivir results published after 139 days of waiting – Brief19
Commentary on Twitter
?Remdesivir trial (ACTT-1) final results finally out.
?Still no mortality benefit. A study with tons of patients could show some small mortality benefit.
?Those who recover, do so a bit faster.
?Not the game-changer that was hyped.via @Brief_19https://t.co/jWRJypJIuS
— Jeremy Faust MD MS (ER physician) (@jeremyfaust) October 8, 2020
[News release – not published yet] Eli Lilly says its monoclonal antibody cocktail is effective in treating Covid-19
9 Oct, 2020 | 09:09h | UTCEli Lilly says its monoclonal antibody cocktail is effective in treating Covid-19 – STAT
Study: Neurologic manifestations occur in most hospitalized Covid‐19 patients
9 Oct, 2020 | 09:11h | UTCCommentaries: COVID-19 neurological symptoms emerge in most hospitalized patients, study says AND Many hospitalized COVID-19 patients exhibit neurological symptoms, study finds – News Medical AND More than 80% of people hospitalized for COVID-19 suffer neurological symptoms, from confusion to altered brain function – Business Insider
Non-invasive positive pressure ventilation in patients with COVID-19
9 Oct, 2020 | 08:58h | UTCNon-Invasive Positive Pressure Ventilation in Patients With COVID-19 – Mayo Clinic Proceedings
Systematic review: Not enough evidence to recommend vena caval filters for the prevention of pulmonary embolism
9 Oct, 2020 | 08:52h | UTCVena caval filters for the prevention of pulmonary embolism – Cochrane Library
Summary: Vena caval filters for the prevention of pulmonary embolism – Cochrane Library
Editorial: The ten reasons why corticosteroid therapy reduces mortality in severe COVID-19
8 Oct, 2020 | 09:15h | UTC
ATS/ERS Updated guidance on the management of COVID-19
8 Oct, 2020 | 09:16h | UTC
COVID-19 and the kidney
8 Oct, 2020 | 09:02h | UTCCOVID-19 and the kidney – Cleveland Clinic Journal of Medicine
Randomized trial: Lopinavir–ritonavir not beneficial for patients admitted to hospital with COVID-19
7 Oct, 2020 | 08:50h | UTCCommentaries: Study: HIV drug of no benefit to hospitalized COVID patients – CIDRAP AND Antiviral monotherapy for hospitalised patients with COVID-19 is not enough – The Lancet AND
Commentary on Twitter
NEW—Lopinavir-ritonavir is not an effective treatment for patients hospitalised with #COVID19: finding from RECOVERY, randomised, controlled, open-label, platform trial https://t.co/RpiUAvWF1I pic.twitter.com/uI3yiQbEgK
— The Lancet (@TheLancet) October 6, 2020
ACEP Clinical Policy: Critical issues related to opioids in adult patients presenting to the emergency department
8 Oct, 2020 | 08:53h | UTCCommentary: ACEP Opioid Policy Statement – Journal Feed
ACP Guidance: Should Remdesivir be used for the treatment of patients with COVID-19?
7 Oct, 2020 | 09:21h | UTCSystematic review: Remdesivir for Adults With COVID-19: A Living Systematic Review for an American College of Physicians Practice Points – Annals of Internal Medicine
Covid-19: Risk of death more than doubled in people who also had flu, English data show
7 Oct, 2020 | 09:11h | UTCCovid-19: Risk of death more than doubled in people who also had flu, English data show – The BMJ
Original study (preprint): Interactions between SARS-CoV-2 and Influenza and the impact of coinfection on disease severity: A test negative design – medRxiv
Commentary on Twitter
People infected with both flu and SARS-CoV-2 are more than twice as likely to die as someone with the new coronavirus alone, emerging evidence analysed by @PHE_uk has found. The data has been published as a preprint on medRxivhttps://t.co/3Qv3gxGRXB
— The BMJ (@bmj_latest) September 23, 2020
Randomized trial: Tranexamic acid during prehospital transport in patients at risk for hemorrhage after injury
7 Oct, 2020 | 09:04h | UTCCommentaries: Prehospital Tranexamic Acid: STAAMP of Approval or Return to Sender? – JAMA Surgery AND Trial examines prehospital administration of blood-clotting agent in severely injured trauma patients – News Medical
Commentary on Twitter
TXA as an adjunct to prehospital #injury management seems to improve #outcome but only in specific subgroups. A nicely done multicenter trial that raises more questions to be answered. @SCCM @JAMASurgery https://t.co/rTQz8qJO0o
— Lewis J. Kaplan (@SCCMPresident) October 5, 2020
Systematic Review: Thoracic imaging tests for the diagnosis of COVID‐19
7 Oct, 2020 | 09:07h | UTCThoracic imaging tests for the diagnosis of COVID‐19 – Cochrane Library
Commentaries: How accurate is chest imaging for diagnosing COVID-19? – Cochrane Library AND Featured Review: Thoracic imaging tests for the diagnosis of COVID-19 – Cochrane Library
Systematic review: Complications of cricothyroidotomy versus tracheostomy in emergency surgical airway management
7 Oct, 2020 | 08:52h | UTC
Long-term health consequences of COVID-19
6 Oct, 2020 | 00:58h | UTCLong-term Health Consequences of COVID-19 – JAMA
Commentary on Twitter
Persistent post-COVID symptoms could be the from direct tissue invasion by the virus, profound inflammation & cytokine storm, related immune system damage, hypercoagulable state, or some combination https://t.co/G8tI9U3TaL @CarlosdelRio7 lfcollins_md @PreetiNMalani
— JAMA (@JAMA_current) October 5, 2020
Meta-analysis: Risk of venous thromboembolism in patients with COVID‐19
6 Oct, 2020 | 00:54h | UTC
Commentaries on Twitter
In a new #RPTH paper, researchers performed a meta-analysis of #VTE risk in #COVID19 patients: 22.7% prevalence in ICU vs. 7.9% in non-ICU patients. Other subgroup analyses reveal heterogeneity and interesting trends…@Cihan_Ay_MD @FlorianMoik NEW: https://t.co/24IWOm5qTe pic.twitter.com/HjnSYq9YKz
— RPTH (@RPTHjournal) September 30, 2020
Meta-analysis of #clotting events in 66 studies including 28173 patients with #COVID19. High #VTE & #PE prevalence in ICU patients indicates a need for thromboprophylaxis research! Read the results at #RPTH by @Cihan_Ay_MD @FlorianMoik https://t.co/24IWOlNPuE @thrombosisday pic.twitter.com/V4Pn2ssBH3
— RPTH (@RPTHjournal) October 5, 2020
What we have found was a trend of decreased VTE rates over time. Earlier studies reported slightly higher VTE rates than more recent ones. What could be the reason? Experience dealing with COVID19 and improved preventive strategies? https://t.co/YDjRyvNmK6 https://t.co/y3Uj5x3QRI pic.twitter.com/0HcFQvMJB8
— Cihan Ay (@Cihan_Ay_MD) September 26, 2020