Critical Care & Emergencies (all articles)
Comprehensive review on the management of pharmaceutical and recreational drug poisoning
1 Dec, 2020 | 08:21h | UTCManagement of pharmaceutical and recreational drug poisoning – Annals of Intensive Care
Colchicine to be investigated as a possible treatment for COVID-19 in the RECOVERY trial
1 Dec, 2020 | 08:08h | UTCCommentary: Gout drug Colchicine to be tested as COVID-19 treatment in UK trial – Reuters
Critically ill patients with COVID-19: A narrative review on prone position
1 Dec, 2020 | 08:07h | UTCCritically Ill Patients with COVID-19: A Narrative Review on Prone Position – Pulmonary Therapy
Randomized trial: Convalescent Plasma does not improve clinical status or overall mortality in severe Covid-19 pneumonia
25 Nov, 2020 | 09:17h | UTCCommentary: New trial of convalescent plasma for covid-19 falls flat, another setback for hyped treatment – Brief19
Commentary on Twitter
A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia @NEJM A well conducted RCT shows no significant differences in clinical status or overall mortality between patients treated with CP and those who received placebo. https://t.co/C6NylbO2At
— Carlos del Rio (@CarlosdelRio7) November 24, 2020
Latest COVID-19 guidelines come out against bamlanivimab, remdesivir
25 Nov, 2020 | 09:10h | UTCLatest COVID-19 guidelines come out against bamlanivimab, remdesivir – ACP Internist
Diagnosis, management, and pathophysiology of arterial and venous thrombosis in COVID-19
24 Nov, 2020 | 09:34h | UTCDiagnosis, Management, and Pathophysiology of Arterial and Venous Thrombosis in COVID-19 – JAMA
Commentary on Twitter
Arterial and venous thrombosis are common in #COVID19, especially in critically ill patients. Thromboprophylaxis should be considered for all hospitalized patients with COVID-19 in the absence of contraindications https://t.co/sjqL7MqGLX
— JAMA (@JAMA_current) November 23, 2020
Data show hospitalized Covid-19 patients are surviving at higher rates, but surge in cases could roll back gains
24 Nov, 2020 | 09:25h | UTC
Updated WHO guideline on drugs for Covid-19 rejects Remdesivir and strongly recommends Corticosteroids for patients with severe and critical disease
20 Nov, 2020 | 08:51h | UTCA living WHO guideline on drugs for covid-19 – The BMJ
Commentary: WHO Guideline Development Group advises against use of remdesivir for COVID-19 – British Medical Journal
Commentary on Twitter
Today the @WHO rejects Remdesivir for #COVID19.
The same drug the @US_FDA gave a full approval.
Because the @WHO reviewed all the data and made the right call.https://t.co/u7GKTRlf37@bmj_latest pic.twitter.com/kVwmDnJRCz— Eric Topol (@EricTopol) November 20, 2020
Older adults with COVID-19 commonly present to the ED with delirium
20 Nov, 2020 | 08:46h | UTCDelirium in Older Patients With COVID-19 Presenting to the Emergency Department – JAMA Network Open
Commentaries: Delirium could signal Covid-19 infection in older adults, study finds – STAT AND Delirium fairly common in older COVID-19 patients – CIDRAP AND Delirium is first symptom for many elderly COVID-19 patients – UPI
Commentary on Twitter
In older ED patients w/ COVID-19 only 56% had a fever, 51% SOB & 50% cough. 28% had delirium & one third of delirious pts lacked typical symptoms. In the ED delirium may the only symptom of #COVID19. @sharon_inouye @ACEPNow @GeriatricEDNews @AGEM_SAEM @JAMANetworkOpen pic.twitter.com/MxjSTx3Ffi
— Maura Kennedy (@MauraKennedyMD) November 19, 2020
Systematic review: Routine laboratory tests are not useful for accurately ruling in or ruling out COVID-19 on their own
20 Nov, 2020 | 08:42h | UTCRoutine laboratory testing to determine if a patient has COVID‐19 – Cochrane Library
Summary: Routine laboratory testing to determine if a patient has COVID‐19 – Cochrane Library
Review: How to ventilate obstructive and asthmatic patients
20 Nov, 2020 | 08:39h | UTCHow to ventilate obstructive and asthmatic patients – Intensive Care Medicine
Commentary on Twitter
Ventilation in #COPD & asthma
➡️ respiratory mechanics/gas exchange
➡️ heart–lung interactions
➡️ HFNO & NIV
➡️ managing invasive MV from intubation to (early) weaning limiting hyperinflation
➡️ long‑term outcome & role of tracheostomy
➡️ future strategieshttps://t.co/zBBlwo7EEI pic.twitter.com/4WPeYJZrh4— Intensive Care Medicine (@yourICM) November 9, 2020
NICE Guideline: Acute coronary syndromes
19 Nov, 2020 | 09:24h | UTCAcute coronary syndromes – National Institute for Health and Care Excellence
Visual summary: STEMI
Visual summary: NSTEMI/unstable angina
Visual summary: Cardiac rehabilitation and secondary prevention
Review: Fluid administration and monitoring in ARDS. Restrictive vs. liberal strategy of fluid administration, assessment of fluid responsiveness, and other topics are discussed
19 Nov, 2020 | 09:19h | UTCFluid administration and monitoring in ARDS: which management? – Intensive Care Medicine
Commentary on Twitter
Fluid administration & monitoring in #ARDS:
➡️ pathophysiology
➡️ fluid therapy
➡️ fluid balance & outcome
➡️ restrictive vs liberal strategy?
➡️ assessing responsiveness
➡️ origin of positive balance & correction
➡️ approach according to ARDS cause/timinghttps://t.co/wIt305B1Ci pic.twitter.com/54whmo7OmC— Intensive Care Medicine (@yourICM) November 12, 2020
CDC Report: 9% readmitted after Covid-19 hospitalization. Risk factors were age ≥65 y, chronic medical conditions, recent hospitalization before Covid-19, and discharge to a skilled nursing facility or with home health care
17 Nov, 2020 | 09:46h | UTCCommentary: 9 percent readmitted after index COVID-19 hospitalization – MedicalXpress AND One in 11 coronavirus patients discharged from a hospital is readmitted within two months, suggesting long-lasting effects of the infection, CDC report warns – Daily Mail
Commentary on Twitter
A new @CDCMMWR finds 9% of the more than 100,000 patients discharged after being hospitalized for #COVID19 were readmitted to the same hospital within 2 months. Learn more: https://t.co/s96NXLxQUE. pic.twitter.com/ugJq9f1gHP
— CDC (@CDCgov) November 9, 2020
Review: Prone positioning for patients with hypoxic respiratory failure related to COVID-19
17 Nov, 2020 | 09:41h | UTC
Commentary on Twitter
What's the evidence for prone positioning for patients with respiratory distress related to #COVID19? A new review answers pressing questions about this common intervention: https://t.co/dh15AuUpD0 #ICU #CriticalCare pic.twitter.com/Y8TzactS70
— CMAJ (@CMAJ) November 11, 2020
Treatment of community-acquired pneumonia in immunocompromised adults: A consensus statement regarding initial strategies
17 Nov, 2020 | 09:40h | UTCEditorial: Management of Community-Acquired Pneumonia in Immunocompromised Adults – CHEST
Systematic review: Evidence-based practices for acute respiratory failure and Acute Respiratory Distress Syndrome
17 Nov, 2020 | 09:37h | UTCCommentary: Best practices for mechanical ventilation in patients with ARDS, COVID-19 – University of Michigan
Podcast on Wilderness Medicine: Pearls on altitude sickness, frostbite, animal bites, thermoregulation, and wound care
17 Nov, 2020 | 09:32h | UTC#242 Wilderness Medicine: Prepare for Disaster – The Curbsiders Internal Medicine Podcast
#AHA20 – A small phase 2 randomized trial showed significantly improved survival with an early ECMO-facilitated resuscitation for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation
16 Nov, 2020 | 01:56h | UTCCommentaries: Early ECMO-Facilitated Resuscitation for Out-of-Hospital Cardiac Arrest – NEJM Journal Watch AND Advanced REperfusion STrategies for refractory cardiac arrest – ARREST – American College of Cardiology AND Cardiac arrest treatment that uses life support machine boosts survival – NIH News Releases
Commentary on Twitter
Latebreaker at #AHA20 @AHAMeetings—Advanced reperfusion strategies for patients with out-of-hospital #cardiacarrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trialhttps://t.co/1TjdlD6G8h pic.twitter.com/zQoRcxF1jO
— The Lancet (@TheLancet) November 14, 2020
#AHA20 – In patients hospitalized for heart failure with iron deficiency, intravenous Ferric carboxymaltose at discharge reduced the risk of heart failure rehospitalizations
16 Nov, 2020 | 01:53h | UTCCommentaries: Intravenous iron reduced rehospitalization risk in people with heart failure – American Heart Association AND AFFIRM-AHF: IV Iron Supplementation Linked to Fewer Repeat Hospitalizations for HF – TCTMD
Commentary on Twitter
Latebreaker at #AHA20 @AHAMeetings—Ferric carboxymaltose for iron deficiency at discharge after acute #heartfailure: AFFIRM-AHF, a multicentre, double-blind, randomised, controlled trial https://t.co/gRKtbsxfba pic.twitter.com/k67HDJMW2b
— The Lancet (@TheLancet) November 14, 2020
Covid-19: Inhaled Nebulized Interferon Beta-1a shows potential for hospitalized patients in preliminary trial
13 Nov, 2020 | 09:33h | UTC
Preliminary study shows fluvoxamine may reduce clinical deterioration in outpatients with symptomatic COVID-19
13 Nov, 2020 | 09:35h | UTCEditorial: COVID-19 Infection—Preventing Clinical Deterioration
Case report: Persistence and evolution of SARS-CoV-2 in an immunocompromised host
13 Nov, 2020 | 09:24h | UTC
Commentary on Twitter (thread – click for more)
This summer, we partnered with the clinical team of an immunosuppressed patient with recurrent COVID and multiple hospitalizations. His NP swab VL reached 1 billion copies 5 months after initial dx. The team's Q: is this pt being re-infected w/ COVID? 1/ https://t.co/vkVerBUUPg
— Jonathan Li (@DrJLi) November 12, 2020
Tranexamic acid after traumatic brain injury: Exploratory analysis combining data from CRASH-2 and CRASH-3 trials suggests reduced mortality
13 Nov, 2020 | 09:21h | UTC
Commentary on Twitter
📊🔍 IPD meta-analysis of #CRASH2 and #CRASH3 trials show rapid #TXA (<3 hrs) reduces early deaths by >20% in both studies
Highly consistent results that #TXA reduces trauma deaths regardless of the location of the #bleeding 🩸
READ @Crit_Care 👉https://t.co/s3vkm6c6Tf pic.twitter.com/og9jYi5tqo
— Clinical Trials Unit – Global Health Trials Group (@CTU_LSHTM) November 11, 2020
Mechanical ventilation in patients with acute brain injury: recommendations of the European Society of Intensive Care Medicine consensus
13 Nov, 2020 | 09:19h | UTC