Tranexamic acid after traumatic brain injury: Exploratory analysis combining data from CRASH-2 and CRASH-3 trials suggests reduced mortality

Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial – Critical Care

Commentary: New analysis combining data from the world’s largest trauma trials provides compelling evidence that rapid tranexamic acid treatment saves lives – London School of Hygiene & Tropical Medicine

Commentary on Twitter

?? IPD meta-analysis of #CRASH2 and #CRASH3 trials show rapid #TXA (<3 hrs) reduces early deaths by >20% in both studies

Highly consistent results that #TXA reduces trauma deaths regardless of the location of the #bleeding ?

READ @Crit_Care ?https://t.co/s3vkm6c6Tf pic.twitter.com/og9jYi5tqo

— Clinical Trials Unit (@CTU_LSHTM) November 11, 2020