Critical Care & Emergencies (all articles)
ESICM guidelines on ARDS: definition, phenotyping and respiratory support strategies
19 Jun, 2023 | 14:18h | UTCSee also: Caring for Patients With Acute Respiratory Distress Syndrome: Summary of the 2023 ESICM Practice Guidelines – JAMA (free for a limited period)
Commentary on Twitter
#ARDS @ESICM guidelines
? definition
? phenotyping
? #HFNO
? CPAP/NIV
? low tidal volume MV
? PEEP & recruitment maneuvers
? prone positioning
? neuromuscular blocking agents
? extracorporeal life support #ECMO #ECLS #ECCO2r#FOAMcc on @yourICM
?️ https://t.co/xGtI2y0vZw pic.twitter.com/H1z7EBxLLo— Intensive Care Medicine (@yourICM) June 16, 2023
RCT | High-dose hemodiafiltration reduces mortality risk in kidney failure patients compared to conventional high-flux hemodialysis
19 Jun, 2023 | 14:17h | UTCEffect of Hemodiafiltration or Hemodialysis on Mortality in Kidney Failure – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
#ERA23: In patients with kidney failure undergoing kidney-replacement therapy, the use of high-dose hemodiafiltration resulted in lower mortality than conventional high-flux hemodialysis. Full results of the CONVINCE trial: https://t.co/NRtQnHm9vo
— NEJM (@NEJM) June 16, 2023
RCT | Video laryngoscopy improves first-attempt intubation, severe complications unchanged
19 Jun, 2023 | 14:15h | UTCVideo versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: Study shows video laryngoscope increases successful intubation on first attempt – Vanderbilt University Medical Center
RCT | Continuous vs. intermittent meropenem administration shows similar mortality and drug-resistance in sepsis patients
19 Jun, 2023 | 14:11h | UTCContinuous vs Intermittent Meropenem Administration in Critically Ill Patients With Sepsis: The MERCY Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Do Prolonged Infusions of β-Lactam Antibiotics Improve Outcomes in Critically Ill Patients With Sepsis? – JAMA (free for a limited period)
See also: Visual Abstract
Commentary: Trial finds no difference between continuous, intermittent meropenem for sepsis patients – CIDRAP
Commentary on Twitter
Continuous administration of meropenem, compared with intermittent administration, does not improve clinically relevant outcomes in critically ill patients with #sepsis. https://t.co/eJ9zdGI4k2 #CCR23 pic.twitter.com/8n2eR9qBPe
— JAMA (@JAMA_current) June 16, 2023
Review | Necessity of antigen testing for Legionella in hospitalized patients with community-acquired pneumonia
19 Jun, 2023 | 13:56h | UTC
M-A | Anticoagulation options for continuous renal replacement therapy in critically ill patients
19 Jun, 2023 | 13:51h | UTC
RCT | Mild hypercapnia after cardiac arrest shows no improvement in neurological outcomes vs. normocapnia
16 Jun, 2023 | 14:15h | UTCMild Hypercapnia or Normocapnia after Out-of-Hospital Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: New data supports current management of CO2 levels in cardiac arrest patients – UCD Dublin
RCT | Multiple electrolytes solution reduces acute kidney injury in pediatric septic shock compared to saline
16 Jun, 2023 | 14:10h | UTCMultiple Electrolytes Solution Versus Saline as Bolus Fluid for Resuscitation in Pediatric Septic Shock: A Multicenter Randomized Clinical Trial – Critical Care Medicine (link to abstract – $ for full-text)
M-A | Mechanical ventilation in patients with acute brain injury
16 Jun, 2023 | 14:03h | UTC
Single-center cohort study | Low-risk PE patients with concerning CT findings – increased hospitalization, but no increased risk of mortality
16 Jun, 2023 | 13:49h | UTCCommentary: Acute Low-Risk Pulmonary Embolism and Concerning CT Findings – American College of Cardiology
RCT | Prehospital use of tranexamic acid in severe trauma cases shows no superiority over placebo
15 Jun, 2023 | 15:16h | UTCPrehospital Tranexamic Acid for Severe Trauma – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: Shining a new light on tranexamic acid for trauma care – Monash University
Commentary on Twitter
Late breaking at #CCR23: In the PATCH-Trauma trial involving adults with major trauma, treatment with tranexamic acid did not result in a greater number of patients surviving with a favorable functional outcome at 6 months than placebo. https://t.co/i8fu34ReCB pic.twitter.com/GEOtRphOBb
— NEJM (@NEJM) June 14, 2023
Cohort Study | Identification of an optimal threshold to define oliguria in critically ill patients
15 Jun, 2023 | 15:05h | UTC
Commentary on Twitter
Identification of an optimal threshold to define oliguria in critically ill patients
Read the full article: https://t.co/4msRdcWZYY@jlvincen @ISICEM #FOAMed #FOAMcc pic.twitter.com/5PfiXkE5FO
— Critical Care (@Crit_Care) June 9, 2023
RCT | Sublingual microcirculatory assessment fails to reduce 30-day mortality in shock patients
15 Jun, 2023 | 15:00h | UTC
Commentary on Twitter
Direct assessment of microcirculation in shock, prospective multicenter RCT
?knowledge of sublingual microcirculatory perfusion variables resulted in significantly more therapy adjustments
?these changes did not improve 30d survival
#FOAMcc @yourICM
?️ https://t.co/Mn5bAqjDtS pic.twitter.com/i3zPwomb0V— Intensive Care Medicine (@yourICM) June 6, 2023
Review | Fluid therapy for critically ill adults with sepsis
14 Jun, 2023 | 14:51h | UTCFluid Therapy for Critically Ill Adults With Sepsis: A Review – JAMA (free for a limited period)
Audio clinical review: Fluid Therapy for Critically Ill Adults With Sepsis – JAMA
M-A | Oseltamivir fails to lower hospitalization risk in adult and adolescent influenza patients
13 Jun, 2023 | 14:12h | UTC
Commentary on Twitter
In this systematic review and meta-analysis of 15 RCTs, oseltamivir was not associated with reduced risk of first hospitalization compared with placebo or standard of care among influenza-infected adult and adolescent outpatients. https://t.co/UEqsbA2JQZ
— JAMA Internal Medicine (@JAMAInternalMed) June 12, 2023
Review | How to improve the efficiency and the safety of real-time ultrasound-guided central venous catheterization
13 Jun, 2023 | 13:47h | UTC
Review | Post-intensive care syndrome
13 Jun, 2023 | 13:44h | UTCPost-intensive care syndrome (PICS): recent updates – Journal of Intensive Care
IDSA 2023 Guidance on the treatment of antimicrobial resistant gram-negative infections
12 Jun, 2023 | 13:58h | UTCRelated:
Review | Volume management with kidney replacement therapy in the critically ill patient
12 Jun, 2023 | 13:43h | UTC
Review | Acute dyspnea in the emergency department
12 Jun, 2023 | 13:33h | UTCAcute dyspnea in the emergency department: a clinical review – Internal and Emergency Medicine
Brief Review | Resistance to unfractionated heparin in the ICU: evaluation and management options
12 Jun, 2023 | 13:32h | UTCResistance to unfractionated heparin in the ICU: evaluation and management options – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
? Resistance to unfractionated heparin in #ICU, evaluation & management options
? monitoring UFH
? mechanisms of resistance
? how to manage UFH resistance
PS check supplement table on IV anticoagulants in ICU#FOAMcc @JerroldLevy @Dr_Cit @foamecmo
?️ https://t.co/ojQw5On5ZL pic.twitter.com/0uPQuwUmOr— Intensive Care Medicine (@yourICM) June 7, 2023
Review | Hemodynamic and respiratory support in pulmonary embolism
12 Jun, 2023 | 13:22h | UTC
Review | Reducing the carbon footprint and resource use of critical care
7 Jun, 2023 | 14:07h | UTCTowards net zero: critical care – The BMJ (free for a limited period)
Commentary on Twitter
ICUs are a considerable contributor to the carbon footprint of hospitals.
This article and #BMJInfographic present ways to reduce wastehttps://t.co/F2DPQcFnCy pic.twitter.com/bHwu9YZEgo
— The BMJ (@bmj_latest) June 3, 2023
Review | Erythrocyte sedimentation rate and C-reactive protein in the ED
7 Jun, 2023 | 13:47h | UTCErythrocyte Sedimentation Rate and C-Reactive Protein in the ED – emDocs
RCT | Tirofiban results in greater likelihood of excellent outcome vs. aspirin in stroke without large vessel occlusion
6 Jun, 2023 | 14:33h | UTCTirofiban for Stroke without Large or Medium-Sized Vessel Occlusion – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Tirofiban for Stroke Without Large or Medium Vessel Occlusion – American College of Cardiology
Commentary on Twitter
Original Article: Tirofiban for Stroke without Large or Medium-Sized Vessel Occlusion (RESCUE BT2) https://t.co/Ul2kfAt9yX
Editorial: Expanding Treatment for Acute Ischemic Stroke beyond Revascularization: https://t.co/G8SAWnGJhS pic.twitter.com/21n0x4YqvK
— NEJM (@NEJM) June 1, 2023