Critical Care | Page 46 of 82 | Links Medicus Content Curation & Alerts in Medicine

State of the Art Review: Prognostication and shared decision making in neurocritical care.

8 Apr, 2022 | 10:53h | UTC

Prognostication and shared decision making in neurocritical care – The BMJ

Commentary on Twitter

It's out TODAY: Thank you @bmj_latest for this opportunity as an invited 'State of the Art Review'💥 on such an important topic‼️ Great job @K_Goostrey 👏👏. Proud of this product: 👉Prognostication and Shared Decision Making in #NCC https://t.co/VeFUlRe0xG @UMassChanNeuro

— S Muehlschlegel MD MPH, FNCS, FCCM, FAAN (@SMuehlschMD) April 7, 2022

M-A: Thrombosis patterns and clinical outcome of COVID-19 vaccine-induced immune thrombotic thrombocytopenia.

8 Apr, 2022 | 10:50h | UTC

Thrombosis patterns and clinical outcome of COVID-19 vaccine-induced immune thrombotic thrombocytopenia: A Systematic Review and Meta-Analysis – International Journal of Infectious Diseases

Case series of Thrombosis with Thrombocytopenia Syndrome after Covid-19 vaccination in the US.

Review: Vaccine-induced immune thrombotic thrombocytopenia.

Vaccine induced immune thrombocytopenia and thrombosis: summary of NICE guidance.

Clinical features of vaccine-induced immune thrombocytopenia and thrombosis.

Review: Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis.

Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.

Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2.3 per million vaccinees. (several articles and resources on the subject)

Stroke: advances in treatment offer hope for patients.

8 Apr, 2022 | 10:23h | UTC

Stroke: advances in treatment offer hope for patients – Evidently Cochrane

Study Commentary | Immediate versus delayed cardiac catheterization in post-arrest patients without ST elevation myocardial infarction: is survivorship bias an important influence?

8 Apr, 2022 | 10:11h | UTC

Immediate Versus Delayed Cardiac Catheterization in Post-Arrest Patients Without ST Elevation Myocardial Infarction: Is Survivorship Bias an Important Influence? – Annals of Emergency Medicine

Original Study: #ESCCongress – RCT: Immediate coronary angiography after out-of-hospital cardiac arrest without ST-segment elevation did not improve outcomes compared to delayed/selective angiography.

Study Commentary | Back to BaSICS (study that compared balanced solution vs. 0.9% saline solution in critically ill patients).

8 Apr, 2022 | 10:09h | UTC

Back to BaSICS – Annals of Emergency Medicine

Original Studies:

BaSICS RCT: Among critically ill patients requiring fluid therapy, treatment with a balanced solution did not lead to reduced mortality compared to a 0.9% saline solution.

BaSICS RCT: Among critically ill patients requiring fluid therapy, there was no difference in mortality with slower (333 mL/h) vs. faster (999 mL/h) intravenous fluid bolus rates.

Perspective: The ongoing saga of normal saline vs. balanced fluids.

RCT: In critically ill adults, using a balanced multielectrolyte solution did not lower the risk of death or acute kidney injury compared to standard saline.

Balanced Crystalloids versus Saline in Critically Ill Adults — A Systematic Review with Meta-Analysis – NEJM Evidence

Cochrane Review: Buffered Solutions Do Not Improve Mortality in Critically Ill Adults and Children Compared to 0,9% Saline

Study Commentary | To Bougie or not to Bougie: Bougie vs. Stylet for first-pass intubation success.

8 Apr, 2022 | 10:07h | UTC

To Bougie or Not to Bougie: Bougie versus Stylet for First-Pass Intubation Success – Annals of Emergency Medicine

Original Study: RCT: In critically ill adults undergoing tracheal intubation, use of a bougie did not significantly increase the incidence of successful first attempt intubation vs. with use of an endotracheal tube with stylet.

Brief Review: How to do lung ultrasound.

8 Apr, 2022 | 09:52h | UTC

How to do lung ultrasound – European Heart Journal – Cardiovascular Imaging

Study finds increased risk of pulmonary embolism up to 110 days after COVID-19.

7 Apr, 2022 | 10:06h | UTC

Risks of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19: nationwide self-controlled cases series and matched cohort study – The BMJ

News Release: Study finds increased risk of serious blood clots up to six months after COVID-19 – BMJ

Editorial: Thromboembolism and bleeding after covid-19

Commentary: Covid: Blood clot risk higher for six months after having virus – BBC

RCT: Among patients with complicated urinary tract infection, oral Tebipenem Pivoxil Hydrobromide was noninferior to intravenous Ertapenem and showed a similar safety profile.

7 Apr, 2022 | 09:53h | UTC

Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary on Twitter

For complicated UTI or acute pyelonephritis, oral tebipenem pivoxil hydrobromide noninferior to IV ertapenem and has a similar safety profile. https://t.co/FRDMQOD0Pn pic.twitter.com/GFQz7SlciX

— NEJM (@NEJM) April 6, 2022

RCT: In patients undergoing intraarterial treatment for stroke, functional outcomes after 3 months were similar with general anesthesia vs. sedation.

7 Apr, 2022 | 08:00h | UTC

General Anesthesia versus Sedation, Both with Hemodynamic Control, during Intraarterial Treatment for Stroke: The GASS Randomized Trial – Anesthesia

Commentary on Twitter

Previous speculations have considered the relationship between anesthetic strategy and patient outcomes. Now, new research suggests general #anesthesia and #sedation produce comparable outcomes after endovascular treatment for stroke. https://t.co/ggLRO8Or3W pic.twitter.com/dLLGA4Vmgk

— Anesthesiology (@_Anesthesiology) March 24, 2022

Major burns: part 2. Anesthesia, intensive care and pain management.

7 Apr, 2022 | 07:59h | UTC

Major burns: part 2. Anaesthesia, intensive care and pain management – BJA Education

RCT: Effects of clazosentan on cerebral vasospasm–related morbidity and all-cause mortality after aneurysmal subarachnoid hemorrhage.

6 Apr, 2022 | 10:47h | UTC

Effects of clazosentan on cerebral vasospasm–related morbidity and all-cause mortality after aneurysmal subarachnoid hemorrhage: two randomized phase 3 trials in Japanese patients – Journal of Neurosurgery

Craniocervical artery dissections: a concise review for clinicians.

6 Apr, 2022 | 10:06h | UTC

Craniocervical Artery Dissections: A Concise Review for Clinicians – Mayo Clinic Proceedings

RCT: Erythropoietin not beneficial for patients with acute kidney injury.

6 Apr, 2022 | 10:02h | UTC

Erythropoietin in Acute Kidney Injury (EAKI): a pragmatic randomized clinical trial – BMC Nephrology

Review: Fulminant myocarditis in adults.

6 Apr, 2022 | 09:55h | UTC

Fulminant myocarditis in adults: a narrative review – Journal of Geriatric Cardiology

Systematic Review: Videolaryngoscopy vs. direct laryngoscopy for adults undergoing tracheal intubation.

5 Apr, 2022 | 09:52h | UTC

Videolaryngoscopy versus direct laryngoscopy for adults undergoing tracheal intubation – Cochrane Library

Commentary from the author on Twitter (thread – click for more)

https://twitter.com/VirtueOfNothing/status/1511007812100390916

Consensus Statement: Definition, diagnosis, and management of COVID-19-associated pulmonary mucormycosis.

5 Apr, 2022 | 09:54h | UTC

Definition, diagnosis, and management of COVID-19-associated pulmonary mucormycosis: Delphi consensus statement from the Fungal Infection Study Forum and Academy of Pulmonary Sciences, India – The Lancet Infectious Diseases

Seminar: Acute coronary syndromes.

5 Apr, 2022 | 09:48h | UTC

Acute coronary syndromes – The Lancet (free for a limited period)

Commentary on Twitter

https://twitter.com/TheLancet/status/1510213032143691776

Review: The intensivist’s perspective of shock, volume management, and hemodynamic monitoring.

5 Apr, 2022 | 08:20h | UTC

The Intensivist’s Perspective of Shock, Volume Management, and Hemodynamic Monitoring – Clinical Journal of the American Society of Nephrology

Commentary on Twitter

https://twitter.com/CJASN/status/1511025812283092992

Podcast: Acute pancreatitis pearls.

5 Apr, 2022 | 08:26h | UTC

#327 Acute Pancreatitis – The Curbsiders

Pericardial effusion and cardiac tamponade: pearls and pitfalls.

5 Apr, 2022 | 08:13h | UTC

Pericardial Effusion and Cardiac Tamponade: Pearls and Pitfalls – emDocs

#ACC22 – RCT: Tranexamic acid reduces the risk of bleeding in patients undergoing noncardiac surgery.

4 Apr, 2022 | 01:37h | UTC

Tranexamic Acid in Patients Undergoing Noncardiac Surgery – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

POISE-3: Tranexamic Acid Reduces Severe Bleeding Risk in Patients Undergoing Noncardiac Surgery – American College of Cardiology

POISE-3: Tranexamic Acid Stems Bleeding During Noncardiac Surgery – TCTMD

Commentaries on Twitter

HOT OFF THE PRESS:POISE-3 Tranexamic Acid
Incidence of composite bleeding outcome significantly lower with tranexamic acid vs placebo; between-group difference in composite CV outcome was small, but noninferiority of tranexamic acid was not established.https://t.co/FyuBliD0Mr

— Steven Cohn, MD (@preopconsult) April 2, 2022

Among patients undergoing noncardiac surgery, the incidence of the composite bleeding outcome was significantly lower with tranexamic acid than with placebo. #ACC22 https://t.co/cYIQhE7YCD pic.twitter.com/l0QKgpEqnG

— NEJM (@NEJM) April 2, 2022

POISE-3 trial results showed a single dose of tranexamic acid before & after surgery significantly ⬇️ severe bleeding risk in pts undergoing noncardiac surgery compared w/ placebo. Findings could have global 🌏 impact, researchers said. https://t.co/LratgyadtE #ACC22 #cvSurg pic.twitter.com/HXlcp6bb0M

— American College of Cardiology (@ACCinTouch) April 2, 2022