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Critical Care

Clinical Review: Diagnosis and management of covid-19 in pregnancy.

27 Apr, 2022 | 08:13h | UTC

Diagnosis and management of covid-19 in pregnancy – The BMJ

 

Perspective: The resilient intensive care unit.

27 Apr, 2022 | 07:57h | UTC

The resilient intensive care unit – Annals of Intensive Care

 

Commentary from the author on Twitter

https://twitter.com/JSalluh/status/1518922117261271041

 

Brief Review: EEG monitoring after cardiac arrest.

27 Apr, 2022 | 07:55h | UTC

EEG monitoring after cardiac arrest – Intensive Care Medicine

 

Commentary on Twitter

 

Brain death: a clinical overview.

27 Apr, 2022 | 07:48h | UTC

Brain death: a clinical overview – Journal of Intensive Care

 

Commentary on Twitter

 

Primary palliative care recommendations for critical care clinicians.

27 Apr, 2022 | 07:46h | UTC

Primary palliative care recommendations for critical care clinicians – Journal of Intensive Care

 

Review: Use of antimicrobials for bloodstream infections in the intensive care unit.

27 Apr, 2022 | 01:34h | UTC

Use of Antimicrobials for Bloodstream Infections in the Intensive Care Unit, a Clinically Oriented Review – Antibiotics

 

Guideline: Use of extracorporeal circulation (ECLS/ECMO) for cardiac and circulatory failure.

26 Apr, 2022 | 08:03h | UTC

Use of extracorporeal circulation (ECLS/ECMO) for cardiac and circulatory failure –A clinical practice Guideline Level 3 – ESC Heart Failure

 

Podcast: Inpatient diabetes pearls.

26 Apr, 2022 | 07:48h | UTC

#330 Inpatient Diabetes with Dr. Dave Lieb – The Curbsiders

 

Echocardiography findings in COVID-19 patients admitted to intensive care units: a multi-national observational study.

25 Apr, 2022 | 01:00h | UTC

Echocardiography findings in COVID-19 patients admitted to intensive care units: a multi-national observational study (the ECHO-COVID study) – Intensive Care Medicine

 

Commentary on Twitter

 

One-year follow-up of a RCT: In ICU patients with severe hypoxemia, there was no difference in long-term mortality and health-related quality of life with lower vs. higher oxygenation targets.

22 Apr, 2022 | 09:32h | UTC

Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia – Intensive Care Medicine

Original Study: Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine

 

Commentary on Twitter

 

Expert Guidance: Strategies to prevent central line-associated bloodstream infections in acute-care hospitals.

20 Apr, 2022 | 10:13h | UTC

Strategies to prevent central line-associated bloodstream infections in acute-care hospitals: 2022 Update – Infection Control & Hospital Epidemiology

 

Commentary on Twitter

Article under a http://creativecommons.org/licenses/by/4.0/ license

 

A nonrandomized controlled study found awake prone position (median of 4.2 hours per day) may not benefit hospitalized adults with Covid-19.

20 Apr, 2022 | 09:56h | UTC

Assessment of Awake Prone Positioning in Hospitalized Adults With COVID-19: A Nonrandomized Controlled Trial – JAMA Internal Medicine

Commentaries:

Prone Positioning for Nonintubated Patients With COVID-19—Potential Dangers of Extrapolation and Intermediate Outcome Variables – JAMA Internal Medicine

Study suggests worse outcomes for awake COVID patients in prone position – CIDRAP

Putting Hospitalized COVID Patients on Their Belly May Not Be a Good Idea After All – HealthDay

Related:

Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis – The Lancet Respiratory Medicine

Prone positioning of patients with moderate hypoxaemia due to covid-19: multicentre pragmatic randomised trial (COVID-PRONE) – The BMJ

RCT: Prone positioning of patients with moderate hypoxia due to COVID-19 – medRxiv

Awake prone positioning for COVID-19 acute hypoxaemic respiratory failure: a randomised, controlled, multinational, open-label meta-trial – The Lancet Respiratory Medicine

Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19: the PROFLO multicenter randomized clinical trial – Critical Care

Prone Positioning of Nonintubated Patients With Coronavirus Disease 2019—A Systematic Review and Meta-Analysis – Critical Care Medicine

 

Commentary on Twitter (thread – click for more)

 

AAOS Guideline: Prevention of surgical site infections after major extremity trauma.

19 Apr, 2022 | 02:35h | UTC

Prevention of Surgical Site Infections After Major Extremity Trauma: Evidence-Based Clinical Practice Guideline – American Academy of Orthopaedic Surgeons

Evidence Review: Prevention of Surgical Site Infection After Extremity Trauma (2022)

 

Pre-transplant EASIX (endothelial activation and stress index) may predict the hazard of sepsis after allogeneic stem cell transplantation.

19 Apr, 2022 | 02:04h | UTC

Pre-transplant EASIX and sepsis after allogeneic stem cell transplantation – Intensive Care Medicine

 

Commentary on Twitter

 

Diarrhea during critical illness: a multicenter cohort study.

18 Apr, 2022 | 10:20h | UTC

Diarrhea during critical illness: a multicenter cohort study – Intensive Care Medicine

 

Commentary on Twitter

 

Guidelines for therapeutic drug monitoring of vancomycin in the framework of model-informed precision dosing.

18 Apr, 2022 | 10:26h | UTC

Clinical Practice Guidelines for Therapeutic Drug Monitoring of Vancomycin in the Framework of Model-Informed Precision Dosing: A Consensus Review by the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring – Pharmaceutics

Related Guideline:

Guideline: Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists

Summary: Therapeutic Monitoring of Vancomycin for Serious Methicillin-resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review by the American Society of Health-system Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists – Clinical Infectious Diseases

 

Commentary on Twitter

https://twitter.com/IDPharmacometrx/status/1514219239732912131

 

Overview of diagnostic criteria and epidemiology of acute kidney injury and acute kidney disease in the critically ill patient.

12 Apr, 2022 | 08:30h | UTC

Overview of Diagnostic Criteria and Epidemiology of Acute Kidney Injury and Acute Kidney Disease in the Critically Ill Patient – Clinical Journal of the American Society of Nephrology

 

Clinical update on COVID-19 for the emergency and critical care clinician: Medical management.

11 Apr, 2022 | 02:00h | UTC

Clinical update on COVID-19 for the emergency and critical care clinician: Medical management – American Journal of Emergency Medicine

 

Review: Atrial fibrillation.

11 Apr, 2022 | 01:57h | UTC

Atrial fibrillation – Nature Reviews Disease Primers (if the link is paywalled, try this one)

Infographic: Atrial fibrillation – Nature Reviews Disease Primers (if the link is paywalled, try this one)

 

Commentary on Twitter

 

RCT: Effect of Gram Stain–Guided initial antibiotic therapy on clinical response in patients with ventilator-associated pneumonia.

11 Apr, 2022 | 01:36h | UTC

Effect of Gram Stain–Guided Initial Antibiotic Therapy on Clinical Response in Patients With Ventilator-Associated Pneumonia: The GRACE-VAP Randomized Clinical Trial – JAMA Network Open

Commentary: Can Gram Stains Guide Antibiotics for Pneumonia in Critical Care? – Medscape (free registration required)

 

Commentary on Twitter

 

Clinical care of severe acute respiratory infections – Tool kit (COVID-19 adaptation, update 2022).

11 Apr, 2022 | 01:45h | UTC

Clinical care of severe acute respiratory infections – Tool kit – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

NCCN Guidelines: CAR T-cell–related toxicities in patients with cancer.

11 Apr, 2022 | 01:32h | UTC

Management of Immunotherapy-Related Toxicities, Version 1.2022, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network

Related:

Reviews: CAR T-Cell Therapy Toxicities and Side Effects

Reviews: CAR T-Cell Therapy Toxicities and Side Effects

Critical Care Management of Chimeric Antigen Receptor T Cell–related Toxicity. Be Aware and Prepared

Reviews: CAR T-Cell Therapy Toxicities and Side Effects

 

M-A: Oxygen targets during mechanical ventilation in the ICU.

11 Apr, 2022 | 01:26h | UTC

Oxygen Targets During Mechanical Ventilation in the ICU: A Systematic Review and Meta-Analysis – Critical Care Explorations

 

M-A: Prophylactic therapies for morbidity and mortality after aneurysmal subarachnoid hemorrhage.

11 Apr, 2022 | 00:52h | UTC

Prophylactic Therapies for Morbidity and Mortality After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Network Meta-Analysis of Randomized Trials – Stroke (link to abstract – $ for full-text)

Related: RCT: Effects of clazosentan on cerebral vasospasm–related morbidity and all-cause mortality after aneurysmal subarachnoid hemorrhage.

 

Commentary on Twitter

 

RCT: In critically ill children requiring noninvasive respiratory support following extubation, high-flow nasal cannula therapy was NOT noninferior to CPAP, resulting in increased time to liberation from respiratory support.

8 Apr, 2022 | 11:07h | UTC

Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Selecting Intermediate Respiratory Support Following Extubation in the Pediatric Intensive Care Unit – JAMA (free for a limited period)

News Release: Trial identifies most effective breathing support for children in intensive care – Imperial College London

 

Commentary on Twitter

 

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