Chest Medicine
Recent advances in the management of pulmonary hypertension with interstitial lung disease.
18 Jul, 2022 | 11:01h | UTC
Review | Imaging the acute respiratory distress syndrome: past, present and future.
15 Jul, 2022 | 13:05h | UTCImaging the acute respiratory distress syndrome: past, present and future – Intensive Care Medicine
Commentary on Twitter
Imaging #ARDS: past, present & future
➡️ physiopathology
➡️ management: PEEP/recruitment; inflation (& hyperinfation)
➡️ effects of proning on ventilation/perfusion
➡️ lung infammation
➡️ #COVID19
➡️ identifying complications
➡️ prognostication
& more!
📎 https://t.co/tEp50muK8J pic.twitter.com/GlME1vTePh— Intensive Care Medicine (@yourICM) July 14, 2022
RCT | Tixagevimab-cilgavimab for treatment of patients hospitalized with COVID-19.
15 Jul, 2022 | 13:02h | UTCCommentary: The potential of tixagevimab–cilgavimab for treating hospitalized COVID-19 patients – News Medical
Related:
Commentary on Twitter
In pts hospitalised w/ COVID-19 receiving remdesivir and other standard care, tixagevimab–cilgavimab did not improve time to sustained recovery but was safe and mortality was lower vs placebo
From the ACTIV-3–TICO Study Group https://t.co/zaaXBQYl5t pic.twitter.com/xe0tmbFrZ9
— The Lancet Respiratory Medicine (@LancetRespirMed) July 11, 2022
Review | Invasive respiratory fungal infections in COVID-19 critically ill patients.
15 Jul, 2022 | 12:58h | UTCInvasive Respiratory Fungal Infections in COVID-19 Critically Ill Patients – Journal of Fungi
A guide for managing patients with stage I NSCLC: deciding between lobectomy, segmentectomy, wedge, SBRT and ablation.
15 Jul, 2022 | 12:55h | UTCA guide for managing patients with stage I NSCLC: deciding between lobectomy, segmentectomy, wedge, SBRT and ablation – Journal of Thoracic Disease
Part 1 – A guide to decision-making
Part 2 – Systematic review of evidence regarding resection extent in generally healthy patients
Part 3 – Systematic review of evidence regarding surgery in compromised patients or specific tumors
Part 4 – Systematic review of evidence involving SBRT and ablation
M-A (mostly of observational studies) | Catheter-directed thrombolysis vs. systemic anticoagulation alone for submassive pulmonary embolism.
15 Jul, 2022 | 12:39h | UTC
Review | Strongyloides stercoralis.
15 Jul, 2022 | 12:23h | UTCStrongyloides stercoralis – Lung (if the link is paywalled, try this one)
Systematic Review | Anti‐IL‐5 therapies for asthma.
14 Jul, 2022 | 12:40h | UTCAnti‐IL‐5 therapies for asthma – Cochrane Library
M-A | Home oxygen for moderate hypoxemia in chronic obstructive pulmonary disease.
13 Jul, 2022 | 11:47h | UTCHome oxygen for moderate hypoxaemia in chronic obstructive pulmonary disease: a systematic review and meta-analysis – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Home oxygen probably makes little or no difference to 3-year mortality in pts with #COPD and moderate hypoxaemia
Systematic review & meta-analysis from Yves Lacasse & colleagues https://t.co/8wDrkEd1LH pic.twitter.com/UoOqW7hngT
— The Lancet Respiratory Medicine (@LancetRespirMed) July 11, 2022
AHA Science Advisory | Elucidating the clinical implications and pathophysiology of pulmonary hypertension in heart failure with preserved ejection fraction: a call to action.
13 Jul, 2022 | 11:40h | UTC
What cardiologists should know about sleep.
13 Jul, 2022 | 11:32h | UTCWhat cardiologists should know about sleep – European Heart Journal (free for a limited period)
RCT | Efficacy and safety of Elexacaftor/Tezacaftor/Ivacaftor in children 6 through 11 years of age with cystic fibrosis heterozygous for F508del and a minimal function mutation.
13 Jul, 2022 | 11:07h | UTCEfficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 Through 11 Years of Age with Cystic Fibrosis Heterozygous for F508del and a Minimal Function Mutation: A Phase 3B, Randomized, Placebo-Controlled Study – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
New coronavirus mutant (BA.2.75) raises concerns in India and beyond.
12 Jul, 2022 | 12:59h | UTCNew coronavirus mutant raises concerns in India and beyond – Associated Press
Perspective | Why BA.5 feels different: the latest wave of infections is a test of our pandemic priorities.
12 Jul, 2022 | 13:03h | UTCWhy BA.5 Feels Different – The Atlantic
M-A | Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2.
12 Jul, 2022 | 12:50h | UTCRelated:
Interpreting a lateral flow SARS-CoV-2 antigen test – The BMJ
ARDS Clinical Practice Guideline.
11 Jul, 2022 | 12:49h | UTCARDS Clinical Practice Guideline 2021 – Journal of Intensive Care
Brief Review | Optimizing aerosolized therapies in critically ill patients.
11 Jul, 2022 | 12:37h | UTCOptimising aerosolized therapies in critically ill patients – Intensive Care Medicine (if the link is paywalled, try this one)
RCT | Neutralizing COVID-19 convalescent plasma does not benefit adults hospitalized with COVID-19.
8 Jul, 2022 | 11:59h | UTC
Interim Analysis | Oral Sabizabulin for high-risk, hospitalized adults with Covid-19.
8 Jul, 2022 | 12:02h | UTCOral Sabizabulin for High-Risk, Hospitalized Adults with Covid-19: Interim Analysis – NEJM Evidence
Consensus statements on the diagnosis and management of obstructive sleep apnea in patients with cardiovascular disease.
8 Jul, 2022 | 11:51h | UTC
M-A | Prenatal antibiotic exposure, asthma, and the atopic march.
8 Jul, 2022 | 11:31h | UTC
Test-negative, case–control study | Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada.
7 Jul, 2022 | 13:00h | UTC
Retrospective Cohort Study | Racial bias and reproducibility in pulse oximetry among medical and surgical inpatients.
7 Jul, 2022 | 12:57h | UTCNews Release: Pulse oximeters missed low oxygen levels in more Black veterans than white veterans – University of Michigan
Related:
Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine
FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT
Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration
Commentary on Twitter
New research found that for individuals in general (medical and surgical) care in hospital, occult hypoxemia was more common for black patients than for white patients https://t.co/DrNlaIE7ho
— The BMJ (@bmj_latest) July 6, 2022
Effect of comprehensive smoke-free legislation on neonatal and infant mortality across 106 middle-income countries.
7 Jul, 2022 | 12:26h | UTC
RCT | High-dose dexamethasone and oxygen support strategies in intensive care unit patients with severe COVID-19 acute hypoxemic respiratory failure.
6 Jul, 2022 | 11:51h | UTC
Commentary on Twitter
In this RCT, high-dose dexamethasone did not significantly improve the 60-day survival. The oxygenation strategy in initially non-intubated patients did not significantly modify the 28-day risk of invasive mechanical ventilation requirement. https://t.co/ZNajW2KBKR
— JAMA Internal Medicine (@JAMAInternalMed) July 5, 2022