RCT | High-dose dexamethasone and oxygen support strategies in intensive care unit patients with severe COVID-19 acute hypoxemic respiratory failure.

High-Dose Dexamethasone and Oxygen Support Strategies in Intensive Care Unit Patients With Severe COVID-19 Acute Hypoxemic Respiratory Failure: The COVIDICUS Randomized Clinical Trial – JAMA Internal Medicine

Commentary on Twitter

In this RCT, high-dose dexamethasone did not significantly improve the 60-day survival. The oxygenation strategy in initially non-intubated patients did not significantly modify the 28-day risk of invasive mechanical ventilation requirement. https://t.co/ZNajW2KBKR

— JAMA Internal Medicine (@JAMAInternalMed) July 5, 2022