Chest Medicine
RCT | Balloon pulmonary angioplasty versus riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension.
8 Aug, 2022 | 11:30h | UTCBalloon pulmonary angioplasty versus riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension (RACE): a multicentre, phase 3, open-label, randomised controlled trial and ancillary follow-up study – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary on Twitter
NEW—Pulmonary vascular resistance reduction was more pronounced with balloon pulmonary angioplasty (BPA) than with riociguat, but treatment-related SAEs were more common with BPA
Read the RACE trial from Xavier Jaïs & colleagues https://t.co/h9r3Qe2mCb
— The Lancet Respiratory Medicine (@LancetRespirMed) August 2, 2022
M-A | Efficacy of Doxycycline for mild-to-moderate community-acquired pneumonia in adults.
4 Aug, 2022 | 14:17h | UTCEfficacy of Doxycycline for Mild-to-moderate Community-acquired Pneumonia in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials – Clinical Infectious Diseases (link to abstract – $ for full-text)
Commentary on Twitter
🆕⚡⚡Systematic Review and Meta-analysis of Randomized Controlled Trials @CIDJournal
Efficacy of Doxycycline for Mild-to-moderate CAP in Adults
The efficacy of doxycycline was comparable to macrolides or fluoroquinolones in mild-moderate CAP #IDTwitter https://t.co/L7UBBUc4Dm— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) July 29, 2022
Position statement | Endoscopic lung volume reduction.
4 Aug, 2022 | 14:10h | UTC
M-A | Global prevalence of non-tuberculous mycobacteria in adults with non-cystic fibrosis bronchiectasis 2006–2021.
3 Aug, 2022 | 14:04h | UTC
Burden of chronic obstructive pulmonary disease and its attributable risk factors in 204 countries and territories, 1990-2019: results from the Global Burden of Disease Study 2019.
2 Aug, 2022 | 12:37h | UTCNews Release: Chronic lung disease remains major public health problem – BMJ Newsroom
Commentary on Twitter
New research finds that despite the decreasing burden of COPD, this disease remains a major public health problem, especially in countries with a low sociodemographic index https://t.co/uUkQYCSmBY
— The BMJ (@bmj_latest) July 30, 2022
An updated review of subglottic stenosis: etiology, evaluation, and management.
2 Aug, 2022 | 12:08h | UTCAn Updated Review of Subglottic Stenosis: Etiology, Evaluation, and Management – Current Pulmonology Reports (if the link is paywalled, try this one)
Systematic Review | Rapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection.
29 Jul, 2022 | 12:39h | UTCRapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection – Cochrane Library
Summary: How accurate are rapid antigen tests for diagnosing COVID-19? – Cochrane Library
M-A | Lung cancer occurrence after an episode of tuberculosis.
29 Jul, 2022 | 12:28h | UTC
M-A | Antiviral drug treatment for nonsevere COVID-19.
27 Jul, 2022 | 12:14h | UTCNews Release: Some antivirals used in nonsevere COVID-19 may reduce hospitalizations and deaths – Canadian Medical Association Journal
Commentary: COVID-19 antivirals may cut risk of hospitalization, death – CIDRAP
M-A | Beneficial and harmful effects of monoclonal antibodies for the treatment and prophylaxis of COVID-19.
27 Jul, 2022 | 12:12h | UTC
NICE Guideline | Pneumonia in adults: diagnosis and management.
26 Jul, 2022 | 13:37h | UTCPneumonia in adults: diagnosis and management – National Institute for Health and Care Excellence
Related Guidelines:
Pneumonia (community-acquired): antimicrobial prescribing
Pneumonia (hospital-acquired): antimicrobial prescribing
Systematic Review | Antiplatelet agents for the treatment of deep venous thrombosis.
26 Jul, 2022 | 12:44h | UTCAntiplatelet agents for the treatment of deep venous thrombosis – Cochrane Library
Summary: Aspirin and similar drugs for the treatment of deep vein thrombosis (DVT) – Cochrane Library
RCT | The effect of inhaled hypertonic saline on lung structure in children aged 3–6 years with cystic fibrosis.
26 Jul, 2022 | 11:50h | UTCThe effect of inhaled hypertonic saline on lung structure in children aged 3–6 years with cystic fibrosis (SHIP-CT): a multicentre, randomised, double-blind, controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary: Inhaled hypertonic saline improves structural airway changes in children with cystic fibrosis – Healio (free registration required)
[PREPRINT] RCT | Inhaled fluticasone not beneficial for outpatients with Covid-19.
25 Jul, 2022 | 13:01h | UTCNews Release: Study finds no benefit to taking fluticasone furoate for COVID-19 symptoms – Duke Clinical Research Institute
Commentary: Asthma Drug Fluticasone Fails as Potential COVID-19 Treatment – HealthDay
Retrospective Cohort Study | Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old.
25 Jul, 2022 | 13:03h | UTCRelated:
Guideline Synopsis | Therapy for mild to moderate asthma.
22 Jul, 2022 | 11:48h | UTCTherapy for Mild to Moderate Asthma – JAMA (free for a limited period)
Original Guideline: 2022 GINA Report, Global Strategy for Asthma Management and Prevention
M-A | Risk factors for asthma exacerbations during pregnancy.
22 Jul, 2022 | 11:09h | UTC
Retrospective cohort study | Impact of ethnicity on the accuracy of measurements of oxygen saturations.
21 Jul, 2022 | 13:15h | UTCRelated:
Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine
FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT
Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration
RCT | Effect of Nintedanib on progression of systemic sclerosis-associated interstitial lung disease over 100 weeks.
21 Jul, 2022 | 13:03h | UTCCommentary: Durable Efficacy for Drug Preventing Lung Progression in Systemic Sclerosis — One-year results sustained over another 48 weeks – MedPage Today (free registration required)
RCT | Using a smartphone application maintains physical activity following pulmonary rehabilitation in patients with COPD.
21 Jul, 2022 | 12:45h | UTC
Review | New antibiotics for hospital-acquired pneumonia and ventilator-associated pneumonia.
20 Jul, 2022 | 11:44h | UTC
Review | The ABCDE approach to difficult weaning from venoarterial extracorporeal membrane oxygenation.
19 Jul, 2022 | 13:49h | UTC
RCT | Intranasal corticosteroids not beneficial for children with obstructive sleep apnea.
19 Jul, 2022 | 13:27h | UTCA trial of intranasal corticosteroids to treat the childhood obstructive sleep apnea syndrome – CHEST (link to abstract – $ for full-text)
Commentaries:
Intranasal corticosteroids not recommended for most children with OSA: study – Medical Dialogues
Commentary on Twitter
In children with obstructive sleep apnea syndrome, treatment with intranasal corticosteroids did not result in significant polysomnographic, neurobehavioral, and symptom changes compared to placebo, according to research in @journal_CHEST. https://t.co/e4bt4NMv5Z pic.twitter.com/FrIBdoMABf
— American Academy of Sleep Medicine (@AASMorg) July 11, 2022
Management of interstitial lung disease (ILD) in myositis syndromes: a practical guide for clinicians.
19 Jul, 2022 | 13:13h | UTC
Cohort Study | Reactogenicity of simultaneous COVID-19 mRNA booster and influenza vaccination.
18 Jul, 2022 | 11:34h | UTCCommentaries:
More (mostly mild) side effects when flu vaccine given with COVID booster – CIDRAP