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Chest Medicine (all articles)

ARDS Clinical Practice Guideline.

11 Jul, 2022 | 12:49h | UTC

ARDS Clinical Practice Guideline 2021 – Journal of Intensive Care

 


Brief Review | Optimizing aerosolized therapies in critically ill patients.

11 Jul, 2022 | 12:37h | UTC

Optimising aerosolized therapies in critically ill patients – Intensive Care Medicine (if the link is paywalled, try this one)

 


RCT | Neutralizing COVID-19 convalescent plasma does not benefit adults hospitalized with COVID-19.

8 Jul, 2022 | 11:59h | UTC

Neutralizing COVID-19 Convalescent Plasma in Adults Hospitalized with COVID-19: A Blinded Randomized Placebo-Controlled Trial – CHEST

Commentary: Study shows convalescent plasma doesn’t benefit severely ill patients hospitalized with COVID-19 – Vanderbilt University Medical Center

 


Interim Analysis | Oral Sabizabulin for high-risk, hospitalized adults with Covid-19.

8 Jul, 2022 | 12:02h | UTC

Oral Sabizabulin for High-Risk, Hospitalized Adults with Covid-19: Interim Analysis – NEJM Evidence

 


Consensus statements on the diagnosis and management of obstructive sleep apnea in patients with cardiovascular disease.

8 Jul, 2022 | 11:51h | UTC

Asian Pacific Society of Cardiology Consensus Statements on the Diagnosis and Management of Obstructive Sleep Apnoea in Patients with Cardiovascular Disease – European Cardiovascular Review

 


M-A | Prenatal antibiotic exposure, asthma, and the atopic march.

8 Jul, 2022 | 11:31h | UTC

Prenatal antibiotic exposure, asthma, and the atopic march: A systematic review and meta-analysis – Allergy

 


Test-negative, case–control study | Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada.

7 Jul, 2022 | 13:00h | UTC

Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada: test negative design study – The BMJ

 


Retrospective Cohort Study | Racial bias and reproducibility in pulse oximetry among medical and surgical inpatients.

7 Jul, 2022 | 12:57h | UTC

Racial bias and reproducibility in pulse oximetry among medical and surgical inpatients in general care in the Veterans Health Administration 2013-19: multicenter, retrospective cohort study – The BMJ

News Release: Pulse oximeters missed low oxygen levels in more Black veterans than white veterans – University of Michigan

Related:

Racial and Ethnic Discrepancy in Pulse Oximetry and Delayed Identification of Treatment Eligibility Among Patients With COVID-19 – JAMA Internal Medicine

Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine

Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial – New England Journal of Medicine

Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19: a systematic review – The Lancet Digital Health

FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT

Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration

 

Commentary on Twitter

 


Effect of comprehensive smoke-free legislation on neonatal and infant mortality across 106 middle-income countries.

7 Jul, 2022 | 12:26h | UTC

Effect of comprehensive smoke-free legislation on neonatal mortality and infant mortality across 106 middle-income countries: a synthetic control study – The Lancet Public Health

 


RCT | High-dose dexamethasone and oxygen support strategies in intensive care unit patients with severe COVID-19 acute hypoxemic respiratory failure.

6 Jul, 2022 | 11:51h | UTC

High-Dose Dexamethasone and Oxygen Support Strategies in Intensive Care Unit Patients With Severe COVID-19 Acute Hypoxemic Respiratory Failure: The COVIDICUS Randomized Clinical Trial – JAMA Internal Medicine

 

Commentary on Twitter


FDA orders Juul to remove all its e-cigarettes from US market.

6 Jul, 2022 | 11:46h | UTC

FDA orders Juul to remove all its e-cigarettes from US market – The BMJ

See also:

FDA orders all Juul e-cigarettes off the market – POLITICO

The FDA orders Juul to pull all of its vaping products from the U.S. market – NPR

FDA orders Juul Labs to remove products from US market – CNN

FDA News Release: FDA Denies Authorization to Market JUUL Products – U.S. Food & Drug Administration


RCT | Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis.

6 Jul, 2022 | 11:31h | UTC

Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis: a randomised, controlled clinical trial – Thorax

Commentary: Does Azithromycin antagonize the effect of inhaled tobramycin in cystic fibrosis? – Medical Dialogues

 

Commentary on Twitter


Exercise-induced laryngeal obstruction (EILO) in athletes: a narrative review by a subgroup of the IOC Consensus on acute respiratory illness in the athlete.

5 Jul, 2022 | 11:59h | UTC

Exercise-induced laryngeal obstruction (EILO) in athletes: a narrative review by a subgroup of the IOC Consensus on ‘acute respiratory illness in the athlete’ – British Journal of Sports Medicine


M-A | Predictors of sleep disordered breathing in children with Down syndrome.

5 Jul, 2022 | 11:33h | UTC

Predictors of sleep disordered breathing in children with Down syndrome: a systematic review and meta-analysis – European Respiratory Review


Review | Cough hypersensitivity and chronic cough.

4 Jul, 2022 | 12:59h | UTC

Cough hypersensitivity and chronic cough – Nature Reviews Disease Primers (if the link is paywalled, try this one)

See also: Infographic (if the link is paywalled, try this one)

 

Commentary on Twitter


Bad news for Paxlovid? Coronavirus can find multiple ways to evade COVID-19 drug.

4 Jul, 2022 | 12:57h | UTC

Bad news for Paxlovid? Coronavirus can find multiple ways to evade COVID-19 drug – Science

See also: SARS-CoV-2 can evade Paxlovid by multiple mechanisms – News Medical


Opinion | FDA: Don’t rush a move to change the Covid-19 vaccine composition.

4 Jul, 2022 | 12:53h | UTC

FDA: Don’t rush a move to change the Covid-19 vaccine composition – STAT


Guideline | Malignancy risk stratification for solitary pulmonary nodule.

4 Jul, 2022 | 12:33h | UTC

Malignancy risk stratification for solitary pulmonary nodule: A clinical practice guideline – Journal of Evidence-Based Medicine


Brief Review | Ventilator-associated pneumonia.

4 Jul, 2022 | 12:15h | UTC

Ventilator-associated pneumonia – Intensive Care Medicine (if the link is paywalled, try this one in PMC)

 

Commentary on Twitter


2022 Guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19.

1 Jul, 2022 | 11:50h | UTC

2022 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19 – The Lancet Oncology

Related:

Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy – Cochrane Library

American Society of Hematology 2021 guidelines for management of venous thromboembolism: prevention and treatment in patients with cancer – Blood Advances

Cancer-Associated Venous Thromboembolic Disease, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network

Venous and Arterial Thromboembolism in Patients With Cancer: JACC: CardioOncology State-of-the-Art Review

 


Two new studies show no benefit of Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19.

1 Jul, 2022 | 11:49h | UTC

Study 1: Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19 (OVID): a randomised, open-label, parallel-group, multicentre, phase 3 trial – The Lancet Haematology

Study 2: Thromboprophylactic low-molecular-weight heparin versus standard of care in unvaccinated, at-risk outpatients with COVID-19 (ETHIC): an open-label, multicentre, randomised, controlled, phase 3b trial – The Lancet Haematology

Commentaries:

Antithrombotic prophylaxis for symptomatic outpatients with COVID-19: less is consistently more – The Lancet Haematology

Antithrombotic Prophylaxis No Help in Outpatients With COVID — Two trials show no differences between patients who received enoxaparin vs standard of care – MedPage Today (free registration required)

 

Commentary on Twitter (thread – click for more)

 


Accuracy of rapid antigen vs. RT-PCR testing for SARS-CoV-2 infection in college athletes during prevalence of the Omicron variant.

1 Jul, 2022 | 11:39h | UTC

Accuracy of Rapid Antigen vs Reverse Transcriptase–Polymerase Chain Reaction Testing for SARS-CoV-2 Infection in College Athletes During Prevalence of the Omicron Variant – JAMA Network Open

 

Commentary on Twitter

 


Review: Nutrition management for critically ill adult patients requiring non-invasive ventilation.

1 Jul, 2022 | 10:42h | UTC

Nutrition Management for Critically Ill Adult Patients Requiring Non-Invasive Ventilation: A Scoping Review – Nutrients

 


Life’s Essential 8: Updating and enhancing the AHA construct of cardiovascular health.

30 Jun, 2022 | 11:31h | UTC

Life’s Essential 8: Updating and Enhancing the American Heart Association’s Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association – Circulation

News Release: American Heart Association adds sleep to cardiovascular health checklist

Commentary: Sleep duration matters for heart health, according to new recommendations – CNN

Related Study: Status of Cardiovascular Health in US Adults and Children Using the American Heart Association’s New “Life’s Essential 8” Metrics: Prevalence Estimates from the National Health and Nutrition Examination Survey (NHANES), 2013-2018 – Circulation

 


Advances in the management of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis.

30 Jun, 2022 | 11:26h | UTC

Advances in the management of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis – The BMJ

 


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