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Chest Medicine (all articles)

Guideline Synopsis | Therapy for mild to moderate asthma.

22 Jul, 2022 | 11:48h | UTC

Therapy for Mild to Moderate Asthma – JAMA (free for a limited period)

Original Guideline: 2022 GINA Report, Global Strategy for Asthma Management and Prevention

Related: Global Initiative for Asthma (GINA) Strategy 2021 – Executive summary and rationale for key changes – European Respiratory Journal

 


M-A | Risk factors for asthma exacerbations during pregnancy.

22 Jul, 2022 | 11:09h | UTC

Risk factors for asthma exacerbations during pregnancy: a systematic review and meta-analysis – European Respiratory Review

 


Retrospective cohort study | Impact of ethnicity on the accuracy of measurements of oxygen saturations.

21 Jul, 2022 | 13:15h | UTC

Impact of ethnicity on the accuracy of measurements of oxygen saturations: A retrospective observational cohort study – eClinicalMedicine

Related:

Racial and Ethnic Discrepancy in Pulse Oximetry and Delayed Identification of Treatment Eligibility Among Patients With COVID-19 – JAMA Internal Medicine

Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine

Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial – New England Journal of Medicine

Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19: a systematic review – The Lancet Digital Health

FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT

Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration

 


RCT | Effect of Nintedanib on progression of systemic sclerosis-associated interstitial lung disease over 100 weeks.

21 Jul, 2022 | 13:03h | UTC

Effect of Nintedanib on Progression of Systemic Sclerosis-Associated Interstitial Lung Disease Over 100 Weeks: Data From a Randomized Controlled Trial – ACR Open Rheumatology

Commentary: Durable Efficacy for Drug Preventing Lung Progression in Systemic Sclerosis — One-year results sustained over another 48 weeks – MedPage Today (free registration required)

 


RCT | Using a smartphone application maintains physical activity following pulmonary rehabilitation in patients with COPD.

21 Jul, 2022 | 12:45h | UTC

Using a smartphone application maintains physical activity following pulmonary rehabilitation in patients with COPD: a randomised controlled trial – Thorax

 


Review | New antibiotics for hospital-acquired pneumonia and ventilator-associated pneumonia.

20 Jul, 2022 | 11:44h | UTC

New Antibiotics for Hospital-Acquired Pneumonia and Ventilator-Associated Pneumonia – Seminars in Respiratory and Critical Care Medicine

 


Review | The ABCDE approach to difficult weaning from venoarterial extracorporeal membrane oxygenation.

19 Jul, 2022 | 13:49h | UTC

The ABCDE approach to difficult weaning from venoarterial extracorporeal membrane oxygenation – Critical Care

 


RCT | Intranasal corticosteroids not beneficial for children with obstructive sleep apnea.

19 Jul, 2022 | 13:27h | UTC

A trial of intranasal corticosteroids to treat the childhood obstructive sleep apnea syndrome – CHEST (link to abstract – $ for full-text)

Commentaries:

Study does not support intranasal corticosteroids for most children with obstructive sleep apnea – Healio

Intranasal corticosteroids not recommended for most children with OSA: study – Medical Dialogues

 

Commentary on Twitter

 


Management of interstitial lung disease (ILD) in myositis syndromes: a practical guide for clinicians.

19 Jul, 2022 | 13:13h | UTC

Management of interstitial lung disease (ILD) in myositis syndromes: a practical guide for clinicians – Best Practice & Research Clinical Rheumatology

 


Cohort Study | Reactogenicity of simultaneous COVID-19 mRNA booster and influenza vaccination.

18 Jul, 2022 | 11:34h | UTC

Reactogenicity of Simultaneous COVID-19 mRNA Booster and Influenza Vaccination in the US – JAMA Network Open

Commentaries:

More (mostly mild) side effects when flu vaccine given with COVID booster – CIDRAP

Reactogenicity and Concomitant Administration of the COVID-19 Booster and Influenza Vaccine – JAMA Network Open

 


Recent advances in the management of pulmonary hypertension with interstitial lung disease.

18 Jul, 2022 | 11:01h | UTC

Recent advances in the management of pulmonary hypertension with interstitial lung disease – European Respiratory Review

 


Review | Imaging the acute respiratory distress syndrome: past, present and future.

15 Jul, 2022 | 13:05h | UTC

Imaging the acute respiratory distress syndrome: past, present and future – Intensive Care Medicine

 

Commentary on Twitter

 


RCT | Tixagevimab-cilgavimab for treatment of patients hospitalized with COVID-19.

15 Jul, 2022 | 13:02h | UTC

Tixagevimab–cilgavimab for treatment of patients hospitalised with COVID-19: a randomised, double-blind, phase 3 trial – The Lancet Respiratory Medicine

Commentary: The potential of tixagevimab–cilgavimab for treating hospitalized COVID-19 patients – News Medical

Related:

Efficacy and safety of intramuscular administration of tixagevimab–cilgavimab for early outpatient treatment of COVID-19 (TACKLE): a phase 3, randomised, double-blind, placebo-controlled trial – The Lancet Respiratory Medicine

Intramuscular AZD7442 (Tixagevimab–Cilgavimab) for Prevention of Covid-19 – New England Journal of Medicine

 

Commentary on Twitter

 


Review | Invasive respiratory fungal infections in COVID-19 critically ill patients.

15 Jul, 2022 | 12:58h | UTC

Invasive Respiratory Fungal Infections in COVID-19 Critically Ill Patients – Journal of Fungi

 


A guide for managing patients with stage I NSCLC: deciding between lobectomy, segmentectomy, wedge, SBRT and ablation.

15 Jul, 2022 | 12:55h | UTC

A guide for managing patients with stage I NSCLC: deciding between lobectomy, segmentectomy, wedge, SBRT and ablation – Journal of Thoracic Disease

Part 1 – A guide to decision-making

Part 2 – Systematic review of evidence regarding resection extent in generally healthy patients

Part 3 – Systematic review of evidence regarding surgery in compromised patients or specific tumors

Part 4 – Systematic review of evidence involving SBRT and ablation

 


M-A (mostly of observational studies) | Catheter-directed thrombolysis vs. systemic anticoagulation alone for submassive pulmonary embolism.

15 Jul, 2022 | 12:39h | UTC

Meta-Analysis Comparing Catheter-Directed Thrombolysis Versus Systemic Anticoagulation Alone for Submassive Pulmonary Embolism – American Journal of Cardiology

 


Review | Strongyloides stercoralis.

15 Jul, 2022 | 12:23h | UTC

Strongyloides stercoralis – Lung (if the link is paywalled, try this one)

 


Systematic Review | Anti‐IL‐5 therapies for asthma.

14 Jul, 2022 | 12:40h | UTC

Anti‐IL‐5 therapies for asthma – Cochrane Library

Summary: Mepolizumab, reslizumab or benralizumab for people already taking inhaled steroids and long-acting beta 2-agonists for their asthma – Cochrane Library

 


M-A | Home oxygen for moderate hypoxemia in chronic obstructive pulmonary disease.

13 Jul, 2022 | 11:47h | UTC

Home oxygen for moderate hypoxaemia in chronic obstructive pulmonary disease: a systematic review and meta-analysis – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 


AHA Science Advisory | Elucidating the clinical implications and pathophysiology of pulmonary hypertension in heart failure with preserved ejection fraction: a call to action.

13 Jul, 2022 | 11:40h | UTC

Elucidating the Clinical Implications and Pathophysiology of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction: A Call to Action: A Science Advisory From the American Heart Association – Circulation

 


What cardiologists should know about sleep.

13 Jul, 2022 | 11:32h | UTC

What cardiologists should know about sleep – European Heart Journal (free for a limited period)

 


RCT | Efficacy and safety of Elexacaftor/Tezacaftor/Ivacaftor in children 6 through 11 years of age with cystic fibrosis heterozygous for F508del and a minimal function mutation.

13 Jul, 2022 | 11:07h | UTC

Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 Through 11 Years of Age with Cystic Fibrosis Heterozygous for F508del and a Minimal Function Mutation: A Phase 3B, Randomized, Placebo-Controlled Study – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)

 


New coronavirus mutant (BA.2.75) raises concerns in India and beyond.

12 Jul, 2022 | 12:59h | UTC

New coronavirus mutant raises concerns in India and beyond – Associated Press

 


Perspective | Why BA.5 feels different: the latest wave of infections is a test of our pandemic priorities.

12 Jul, 2022 | 13:03h | UTC

Why BA.5 Feels Different – The Atlantic

 


M-A | Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2.

12 Jul, 2022 | 12:50h | UTC

Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2: An updated systematic review and meta-analysis with meta-regression analyzing influencing factors – PLOS Medicine

Related:

Interpreting a lateral flow SARS-CoV-2 antigen test – The BMJ

Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection – Cochrane Library

 


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