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Chest Medicine (all articles)

M-A | Diagnostic accuracy of urinary antigen tests for pneumococcal pneumonia among patients with acute respiratory failure suspected pneumonia.

12 Aug, 2022 | 14:28h | UTC

Diagnostic accuracy of urinary antigen tests for pneumococcal pneumonia among patients with acute respiratory failure suspected pneumonia: a systematic review and meta-analysis – BMJ Open

 


M-A | Medications for the treatment of pulmonary arterial hypertension.

12 Aug, 2022 | 14:32h | UTC

Medications for the treatment of pulmonary arterial hypertension: a systematic review and network meta-analysis – European Respiratory Review

 


RCT | Tobramycin inhalation solution is effective in adults with bronchiectasis with pseudomonas aeruginosa infection.

11 Aug, 2022 | 12:15h | UTC

A Double-blind Randomized Placebo-controlled Phase-3 Trial of Tobramycin Inhalation Solution in Adults with Bronchiectasis with Pseudomonas aeruginosa Infection – CHEST

Commentary: Tobramycin Tames Infection in Bronchiectasis – Medscape (free registration required)

Related Study: Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis: a randomised, controlled clinical trial – Thorax

 


Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions.

11 Aug, 2022 | 12:02h | UTC

Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions – Intensive Care Medicine

 

Commentary on Twitter

 


Systematic Review | Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis.

11 Aug, 2022 | 11:59h | UTC

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis – Cochrane Library

Summary: Inhaling antibiotics to treat temporary worsening of lung infection in people with cystic fibrosis – Cochrane Library

 


Systematic Review | Catheter‐directed therapies for the treatment of high risk (massive) and intermediate risk (submassive) acute pulmonary embolism.

10 Aug, 2022 | 12:32h | UTC

Catheter‐directed therapies for the treatment of high risk (massive) and intermediate risk (submassive) acute pulmonary embolism – Cochrane Library

Summary: Minimally invasive treatments to dissolve blood clots in the lungs (acute pulmonary embolism) – Cochrane Library

 


Systematic Review | Smoking cessation for secondary prevention of cardiovascular disease.

9 Aug, 2022 | 12:42h | UTC

Smoking cessation for secondary prevention of cardiovascular disease – Cochrane Library

Summary: Does stopping smoking make people with heart disease less likely to have another heart attack? – Cochrane Library

 


RCT | Effectiveness of Varenicline and Cytisine for alcohol use reduction among people with HIV and substance use.

9 Aug, 2022 | 12:35h | UTC

Effectiveness of Varenicline and Cytisine for Alcohol Use Reduction Among People With HIV and Substance Use: A Randomized Clinical Trial – JAMA Network Open

Commentary: Varenicline and cytisine not more efficacious than nicotine to treat risky drinking and smoking, study says – News Medical / Vanderbilt University Medical Center

 

Commentary on Twitter

 


Systematic Review | Impact of low‐dose computed tomography screening on lung cancer‐related mortality.

8 Aug, 2022 | 11:52h | UTC

Impact of low‐dose computed tomography (LDCT) screening on lung cancer‐related mortality – Cochrane Library

Summary: Impact of computed tomography (CT) on lung cancer screening – Cochrane Library

Related:

Association of computed tomography screening with lung cancer stage shift and survival in the United States: quasi-experimental study – The BMJ

Screening for Lung Cancer: CHEST Guideline and Expert Panel Report.

USPSTF Statement: begin screening for lung cancer at age 50 years instead of 55 years for patients at risk

Meta-analysis: Lung cancer screening using low-dose computed tomography reduces lung cancer–specific mortality, albeit with a tradeoff of likely overdiagnosis

 


RCT | Temporary transvenous phrenic nerve stimulation does not benefit difficult-to-wean patients in the ICU.

8 Aug, 2022 | 11:41h | UTC

Randomized Clinical Study of Temporary Transvenous Phrenic Nerve Stimulation in Difficult-to-Wean Patients – American Journal of Respiratory and Critical Care Medicine

Editorial: Transvenous Phrenic Nerve Stimulation: A Novel Therapy Gathering Pace – American Journal of Respiratory and Critical Care Medicine

 


RCT | Balloon pulmonary angioplasty versus riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension.

8 Aug, 2022 | 11:30h | UTC

Balloon pulmonary angioplasty versus riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension (RACE): a multicentre, phase 3, open-label, randomised controlled trial and ancillary follow-up study – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 


M-A | Efficacy of Doxycycline for mild-to-moderate community-acquired pneumonia in adults.

4 Aug, 2022 | 14:17h | UTC

Efficacy of Doxycycline for Mild-to-moderate Community-acquired Pneumonia in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials – Clinical Infectious Diseases (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Position statement | Endoscopic lung volume reduction.

4 Aug, 2022 | 14:10h | UTC

Position statement on endoscopic lung volume reduction in South Africa: 2022 update – African Journal of Thoracic and Critical Care Medicine

 


M-A | Global prevalence of non-tuberculous mycobacteria in adults with non-cystic fibrosis bronchiectasis 2006–2021.

3 Aug, 2022 | 14:04h | UTC

Global prevalence of non-tuberculous mycobacteria in adults with non-cystic fibrosis bronchiectasis 2006–2021: a systematic review and meta-analysis – BMJ Open

 


Burden of chronic obstructive pulmonary disease and its attributable risk factors in 204 countries and territories, 1990-2019: results from the Global Burden of Disease Study 2019.

2 Aug, 2022 | 12:37h | UTC

Burden of chronic obstructive pulmonary disease and its attributable risk factors in 204 countries and territories, 1990-2019: results from the Global Burden of Disease Study 2019 – The BMJ

News Release: Chronic lung disease remains major public health problem – BMJ Newsroom

 

Commentary on Twitter

 


An updated review of subglottic stenosis: etiology, evaluation, and management.

2 Aug, 2022 | 12:08h | UTC

An Updated Review of Subglottic Stenosis: Etiology, Evaluation, and Management – Current Pulmonology Reports (if the link is paywalled, try this one)

 


Systematic Review | Rapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection.

29 Jul, 2022 | 12:39h | UTC

Rapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection – Cochrane Library

Summary: How accurate are rapid antigen tests for diagnosing COVID-19? – Cochrane Library

 


M-A | Lung cancer occurrence after an episode of tuberculosis.

29 Jul, 2022 | 12:28h | UTC

Lung cancer occurrence after an episode of tuberculosis: a systematic review and meta-analysis – European Respiratory Review

 


M-A | Antiviral drug treatment for nonsevere COVID-19.

27 Jul, 2022 | 12:14h | UTC

Antiviral drug treatment for nonsevere COVID-19: a systematic review and network meta-analysis – Canadian Medical Association Journal

News Release: Some antivirals used in nonsevere COVID-19 may reduce hospitalizations and deaths – Canadian Medical Association Journal

Commentary: COVID-19 antivirals may cut risk of hospitalization, death – CIDRAP

 


M-A | Beneficial and harmful effects of monoclonal antibodies for the treatment and prophylaxis of COVID-19.

27 Jul, 2022 | 12:12h | UTC

Beneficial and harmful effects of monoclonal antibodies for the treatment and prophylaxis of COVID-19: a systematic review and meta-analysis of randomized controlled trials – American Journal of Medicine

 


NICE Guideline | Pneumonia in adults: diagnosis and management.

26 Jul, 2022 | 13:37h | UTC

Pneumonia in adults: diagnosis and management – National Institute for Health and Care Excellence

Related Guidelines:

Pneumonia (community-acquired): antimicrobial prescribing

Pneumonia (hospital-acquired): antimicrobial prescribing

Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America – American Journal of Respiratory and Critical Care Medicine

 


Systematic Review | Antiplatelet agents for the treatment of deep venous thrombosis.

26 Jul, 2022 | 12:44h | UTC

Antiplatelet agents for the treatment of deep venous thrombosis – Cochrane Library

Summary: Aspirin and similar drugs for the treatment of deep vein thrombosis (DVT) – Cochrane Library

 


RCT | The effect of inhaled hypertonic saline on lung structure in children aged 3–6 years with cystic fibrosis.

26 Jul, 2022 | 11:50h | UTC

The effect of inhaled hypertonic saline on lung structure in children aged 3–6 years with cystic fibrosis (SHIP-CT): a multicentre, randomised, double-blind, controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

Commentary: Inhaled hypertonic saline improves structural airway changes in children with cystic fibrosis – Healio (free registration required)

 


[PREPRINT] RCT | Inhaled fluticasone not beneficial for outpatients with Covid-19.

25 Jul, 2022 | 13:01h | UTC

Inhaled Fluticasone for Outpatient Treatment of Covid-19: A Decentralized, Placebo-controlled, Randomized, Platform Clinical Trial – medRxiv

News Release: Study finds no benefit to taking fluticasone furoate for COVID-19 symptoms – Duke Clinical Research Institute

Commentary: Asthma Drug Fluticasone Fails as Potential COVID-19 Treatment – HealthDay

 


Retrospective Cohort Study | Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old.

25 Jul, 2022 | 13:03h | UTC

Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old: A nationwide, retrospective cohort study in Sweden – The Lancet Regional Health Europe

Related:

Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada: test negative design study – The BMJ

Association of Receipt of the Fourth BNT162b2 Dose With Omicron Infection and COVID-19 Hospitalizations Among Residents of Long-term Care Facilities – JAMA Internal Medicine

Short term, relative effectiveness of four doses versus three doses of BNT162b2 vaccine in people aged 60 years and older in Israel: retrospective, test negative, case-control study – The BMJ

Fourth Dose of BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting – New England Journal of Medicine

 


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