Chest Medicine
RCT | Bronchodilators don’t improve smoking-related respiratory symptoms in people without COPD.
5 Sep, 2022 | 14:40h | UTCNews Release: Bronchodilators don’t improve smoking-related respiratory symptoms in people without COPD – NIH News Releases
Original Study: Bronchodilators in Tobacco-Exposed Persons with Symptoms and Preserved Lung Function – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
This trial involving symptomatic, tobacco-exposed persons with preserved lung function onspirometry showed no benefit to the use of dual bronchodilator therapy. https://t.co/kXqXHMl2xx pic.twitter.com/KAMuI4Jajo
— NEJM (@NEJM) September 4, 2022
FDA authorizes updated COVID boosters from Moderna and Pfizer.
5 Sep, 2022 | 14:36h | UTCFDA authorizes updated COVID boosters from Moderna and Pfizer – CIDRAP
FDA News Release: Coronavirus (COVID-19) Update: FDA Authorizes Moderna, Pfizer-BioNTech Bivalent COVID-19 Vaccines for Use as a Booster Dose – U.S. Food & Drug Administration
Review | Right ventricular function across the spectrum of health and disease.
5 Sep, 2022 | 14:30h | UTCRight ventricular function across the spectrum of health and disease – Heart
Commentary on Twitter
Right ventricular function across the spectrum
of health and disease https://t.co/3i9iiddsyV #echofirst #Cardiotwitter #CardioEd #MedEd #CardioTwitteros pic.twitter.com/Q219nvnu6v— Sergio Moreno M (@Serginho1409) July 11, 2022
Under a http://creativecommons.org/licenses/by-nc/4.0/ license
RCT | Maintaining continuous endotracheal cuff pressure control through an automated electronic device did not reduce the incidence of ventilator-associated respiratory infection.
5 Sep, 2022 | 14:25h | UTC
Systematic Review | Antifungal therapies for allergic bronchopulmonary aspergillosis in people with cystic fibrosis.
5 Sep, 2022 | 14:15h | UTC
Review | Covid-19 vaccines — immunity, variants, boosters.
1 Sep, 2022 | 11:57h | UTCCovid-19 Vaccines — Immunity, Variants, Boosters – New England Journal of Medicine
RCT | Driving pressure-guided ventilation and postoperative pulmonary complications in thoracic surgery.
1 Sep, 2022 | 11:52h | UTC
Study Commentary | Zinc for the prevention or treatment of respiratory tract infections: a new systematic review.
1 Sep, 2022 | 11:46h | UTC
Characteristics and outcomes of anterior mediastinal cystic lesions diagnosed on chest MRI: implications for management of cystic lesions.
1 Sep, 2022 | 11:41h | UTC
RCT | Outpatient convalescent plasma therapy for high-risk patients with early COVID-19.
31 Aug, 2022 | 11:48h | UTC
Cohort Study | Electrocardiographic findings associated with early clinical deterioration in acute pulmonary embolism.
31 Aug, 2022 | 11:30h | UTC
Brief Review | Physiology of extracorporeal CO2 removal.
31 Aug, 2022 | 11:28h | UTCPhysiology of extracorporeal CO2 removal – Intensive Care Medicine
Consensus statement on intraoperative and postoperative interventions to reduce pulmonary complications after esophagectomy.
30 Aug, 2022 | 12:09h | UTC
#ESCCongress | In critically ill patients with COVID-19, full-dose anticoagulation reduced thrombotic events but increased the risk of bleeding.
30 Aug, 2022 | 12:12h | UTCNews Release: Trial supports full-dose anticoagulation to prevent blood clots in COVID-19 patients – European Society of Cardiology
Related:
Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library
Commentary on Twitter
#OriginalResearch SimPub #ESCCongress: In the #COVID-PACT 2×2 factorial RCT, full-dose prophylactic anticoagulation, but not the addition of clopidogrel, reduced thrombotic complications but w/ increased bleeding among critically-ill patients w/ COVID-19 https://t.co/UNxFCIC5B9 pic.twitter.com/p5LGmpCGeL
— Circulation (@CircAHA) August 29, 2022
#ESCCongress | 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension.
29 Aug, 2022 | 12:18h | UTCNews Release: Pulmonary hypertension guidelines call for earlier diagnosis – European Society of Cardiology
#ESCCongress – RCT | In comatose survivors of out-of-hospital cardiac arrest, a restrictive vs. a liberal oxygenation strategy resulted in similar incidences of death, severe disability, and coma.
29 Aug, 2022 | 12:12h | UTCOxygen Targets in Comatose Survivors of Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: Restrictive oxygenation in post cardiac arrest patients is not harmful – European Society of Cardiology
Commentary on Twitter
BOX Oxygen: This RCT found no difference in the rate of death or severe disability/coma when mechanically ventilated patients following out-of-hospital cardiac arrest were managed with higher or lower oxygenation targets. #ESCCongress https://t.co/qqtd4SyVrl pic.twitter.com/q73gqSuAn4
— NEJM (@NEJM) August 27, 2022
Meta-analysis of randomized trials | Intensive vs. short face-to-face smoking cessation interventions.
29 Aug, 2022 | 12:03h | UTC
Systematic Review | Pulmonary rehabilitation versus usual care for adults with asthma.
26 Aug, 2022 | 13:12h | UTCPulmonary rehabilitation versus usual care for adults with asthma – Cochrane Library
Commentary on Twitter
Very excited to see our new @CochraneAirways review in print! A modest body of evidence highlights likely benefits of #pulmonaryrehab on ex.tol and QoL in people with #asthma. Big thanks to @EvidSynIRL for supporting @ccass2000's mentorship! Link here: https://t.co/DlgdTqETtb pic.twitter.com/RAtOO0Oam6
— Christian Osadnik (@COsadnik) August 23, 2022
Retrospective Cohort Study | Clinical and genetic risk factors for acute incident venous thromboembolism in ambulatory patients with COVID-19.
24 Aug, 2022 | 14:17h | UTC
Commentary on Twitter
Ambulatory #COVID19 was associated with a substantially increased risk of incident venous thromboembolism, but this risk was greatly reduced in fully vaccinated people with breakthrough infection. https://t.co/98zKNfEWaU #Research
— JAMA Internal Medicine (@JAMAInternalMed) August 18, 2022
Retrospective Cohort Study | Association of COVID-19 vs. Influenza with risk of arterial and venous thrombotic events among hospitalized patients.
24 Aug, 2022 | 14:16h | UTCCommentary: Higher risk of vein blood clots in COVID vs flu patients – CIDRAP
News Release: People with Severe COVID-19 Face Increased Risk of Life-Threatening Blood Clots – Penn Medicine News
Commentary on Twitter
The risk of blood clots in hospitalized patients with Covid vs influenza was increased 60-90% within 90 days, for venous but not arterial thrombosishttps://t.co/wPHf18NYYB @JAMA_current
Retrospective, much smaller influenza cohort from 2018-2019 pic.twitter.com/sClYHF0J6U— Eric Topol (@EricTopol) August 16, 2022
Updated systematic review and critical appraisal: prediction models for diagnosis and prognosis of covid-19.
23 Aug, 2022 | 13:31h | UTCCommentary: Update to living systematic review on prediction models for diagnosis and prognosis of covid-19 – The BMJ
Commentary on Twitter
NEW update in @bmj_latest
606 prognostic models for #COVID19 identified – 29 had low risk of bias, 32 had unclear risk of bias, AND 545 HAD HIGH RISK OF BIAS!
+Poorly reported – use TRIPOD please https://t.co/tVA0xHXdRu#epitwitter #statstwitter pic.twitter.com/n71vdgY8wM
— Gary Collins 🇪🇺 (@GSCollins) August 22, 2022
RCT | Stopping vs. continuing long-term mepolizumab treatment in severe eosinophilic asthma.
23 Aug, 2022 | 12:55h | UTC
Commentary on Twitter
This randomised study demonstrates increased exacerbation risk and a decrease in asthma control in patients with severe eosinophilic asthma who stop mepolizumab treatment after long-term use, when compared with those who continue treatment. https://t.co/HYCH0TsU9E pic.twitter.com/rW6hmHgJlj
— ERS publications (@ERSpublications) January 6, 2022
Guideline Summary | Recommendations for the outpatient drug treatment of patients with COVID-19.
22 Aug, 2022 | 12:25h | UTC
ATS/ERS/JRS/ALAT Research Statement | Syndrome of combined pulmonary fibrosis and emphysema.
22 Aug, 2022 | 12:12h | UTC
Commentary on Twitter
In this international statement, we propose a research definition of CPFE (for research purposes), +classification criteria of CPFE clinical syndrome for clinicians. Hopefully both will help the field move forward.Thanks to all participants! @ATS_Assemblies @EuroRespSoc @ALATorax https://t.co/PphDomCVJc pic.twitter.com/QLboKM7Tcx
— Vincent Cottin (@OrphaLung) August 18, 2022
RCT | Mepolizumab for urban children with exacerbation-prone eosinophilic asthma.
22 Aug, 2022 | 12:09h | UTCMepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial – The Lancet (link to abstract – $ for full-text)
Commentary: Mepolizumab Cuts Exacerbations in Children With Severe Asthma – HealthDay