Chest Medicine
Series | Sleep and sleep disorders.
23 Sep, 2022 | 13:13h | UTCHomepage: Sleep and sleep disorders (free registration required for all articles)
Editorial: Waking up to the importance of sleep
Series:
Understanding and approaching excessive daytime sleepiness
Circadian rhythms and disorders of the timing of sleep
Sleep function: an evolutionary perspective
Commentaries:
How and why do human beings sleep?
Social determinants and health disparities affecting sleep
Long covid—an update for primary care.
23 Sep, 2022 | 13:10h | UTCLong covid—an update for primary care – The BMJ
RCT | Operative vs. nonoperative treatment of acute unstable chest wall injuries.
22 Sep, 2022 | 13:13h | UTCOperative vs Nonoperative Treatment of Acute Unstable Chest Wall Injuries: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Invited commentary: Operative Treatment of Acute Unstable Chest Wall Injuries—Let Us All Take a Deep Breath – JAMA Surgery (free for a limited period)
Author Interview: Operative vs Nonoperative Treatment of Acute Unstable Chest Wall Injuries – JAMA
Related:
RCT | Rib fixation is not beneficial for non–ventilator-dependent chest wall injuries.
Commentary on Twitter
Patients who are on mechanical ventilation may benefit from surgical treatment of unstable chest wall injuries, but non-ventilated patients demonstrated little benefit from surgical intervention. https://t.co/MlQ9qIrKon
— JAMA Surgery (@JAMASurgery) September 21, 2022
RCT | Helmet noninvasive ventilation no better than usual respiratory support for acute hypoxemic respiratory failure due to COVID-19.
22 Sep, 2022 | 13:11h | UTC
Commentary on Twitter
Helmet noninvasive ventilation did not significantly reduce 28-day mortality vs usual respiratory support among patients with acute hypoxemic respiratory failure due to #COVID19 #pneumonia. https://t.co/LCuuY9UqZA #Research pic.twitter.com/NgdzwCVJ4V
— JAMA (@JAMA_current) September 20, 2022
Understanding post-COVID-19 interstitial lung disease: a new fibroinflammatory disease entity.
22 Sep, 2022 | 13:09h | UTC
Commentary on Twitter
Post #COVID19 interstitial lung disease?
🦠 PC-ILD fibroinflammatory disease
🦠 etiopathogenesis
Identifying risk factors & understanding immunopathomechanisms critical to facilitate early intervention to prevent, slow or arrest lung damage progression.
📎https://t.co/OEM2W9bAEd pic.twitter.com/m4w4qUXl9r— Intensive Care Medicine (@yourICM) September 8, 2022
Pulmonary artery denervation for pulmonary arterial hypertension: a sham-controlled randomized trial.
21 Sep, 2022 | 13:21h | UTCCommentaries:
Pulmonary Artery Denervation in Idiopathic PAH Ups 6-Minute Walk Test – TCTMD
Commentary on Twitter
#TCT2022 #JACCINT LBCT SimPub: PADN-CFDA trial included 128 pts w/ #cvPAH. At 6-month follow-up, PADN assoc. w/ a ⬆️ improvement in 6MWD, PVR, RV function, & ⬇️ NT-proBNP. Clinical worsening was ⬇️ & satisfactory clinical response was ⬆️ in the PADN group. https://t.co/3IVaUwCgOT pic.twitter.com/bylhcA4GrQ
— JACC Journals (@JACCJournals) September 18, 2022
ISHLT consensus statement | Perioperative management of patients with pulmonary hypertension and right heart failure undergoing surgery.
21 Sep, 2022 | 13:15h | UTC
The Lancet Commission on lessons for the future from the COVID-19 pandemic – “a massive global failure.”
16 Sep, 2022 | 13:03h | UTCHomepage: The Lancet COVID-19 Commission
The Lancet Commission on lessons for the future from the COVID-19 pandemic
Editorial: COVID-19: the case for prosociality
Infographic: COVID-19 response: a massive global failure
Commentaries:
WHO responds to The Lancet COVID-19 Commission – World Health Organization
Covid-19: Commission describes “massive global failures” of pandemic response – The BMJ
Lancet Commission on COVID-19 response: ‘Massive global failure’ – CIDRAP
The Lancet Commission | Towards the elimination of chronic obstructive pulmonary disease.
16 Sep, 2022 | 13:02h | UTCHomepage: Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission – The Lancet
Commission: Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission
Editorial: COPD: from an end-stage disease to lifelong lung health
Invited Commentary: Classification of COPD: fostering prevention and precision medicine in the Lancet Commission on COPD
Commentary: Proposed classification of COPD according to major risk factors – News Medical
M-A of randomized trials | In patients hospitalized with community-acquired pneumonia, corticosteroids reduce the need for mechanical ventilation without significant effects on mortality, treatment failure, or adverse events.
14 Sep, 2022 | 13:16h | UTCEffect of corticosteroids on mortality and clinical cure in community-acquired pneumonia: A systematic review, meta-analysis, and meta-regression of randomized control trials – CHEST Journal (link to abstract – $ for full-text)
RCT | Dexamethasone is not effective for the treatment of dyspnea in patients with cancer and increases the risk of adverse events.
13 Sep, 2022 | 13:22h | UTCEffect of dexamethasone on dyspnoea in patients with cancer (ABCD): a parallel-group, double-blind, randomised, controlled trial – The Lancet Oncology (free for a limited period)
Commentary on Twitter
Our phase III randomized study, published in Lancet Oncology today, showed high-dose steroid didn’t improve SOB and should not be used routinely in pts with lung ca for SOB palliation. My personal link in Lancet Oncology article ⁰https://t.co/Mj0AAzMujB pic.twitter.com/FMG7csHZsn
— Joe Y Chang (@JoeChangMD) September 7, 2022
RCT | A double-dose influenza vaccination during hospitalization for acute coronary syndrome did not improve outcomes compared to standard-dose outpatient vaccination.
13 Sep, 2022 | 13:19h | UTC
Commentary on Twitter
In the VIP-ACS trial, among patients hospitalised with an ACS, double dose influenza vaccination before discharge does not reduce cardiovascular and pulmonary outcomes compared with standard dose vaccination 👉https://t.co/L9e7MXWfWV#EHJ #ESCCongress @ehj_ed @rladeiraslopes pic.twitter.com/95o50krrwm
— European Society of Cardiology Journals (@ESC_Journals) August 31, 2022
RCT | Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19.
13 Sep, 2022 | 13:16h | UTC
Commentaries on Twitter
Interesting results in the #PANAMO trial of vilobelimab, an anti-C5a antibody, in critically ill ICU patients w/ COVID19.
People on MV (n=386) randomized to vilobelimab vs placebo. Mortality was (maybe) reduced in a subgroup w/ more severe illness…🤔https://t.co/bO5XiRptag
1/ pic.twitter.com/EUNda67T9j— Nick Mark MD (@nickmmark) September 11, 2022
NEW Research—In addition to SOC, vilobelimab improves survival of invasive mechanically ventilated patients w/ #COVID19 and leads to a significant decrease in mortality
Read the PANAMO study from Prof Alexander Vlaar & colleagues here https://t.co/k5UuqQtqyE pic.twitter.com/Xmrb76ZpzW
— The Lancet Respiratory Medicine (@LancetRespirMed) September 8, 2022
RCT | Dipeptidyl peptidase-1 inhibition does not improve outcomes in patients hospitalized with COVID-19.
13 Sep, 2022 | 13:15h | UTC
Commentary on Twitter
NEW Research—Brensocatib treatment did not improve clinical status at day 29 in patients hospitalised with #COVID19
Being presented at #ERSCongress, ALERT 3 session, Sept 5 from 13:15 BST
From @profjdchalmers, @keirholly, @meretelong & colleagueshttps://t.co/Vlqhfs6qtj pic.twitter.com/5CY0LS4Bvy
— The Lancet Respiratory Medicine (@LancetRespirMed) September 5, 2022
M-A of randomized trials | High-flow nasal cannula oxygen therapy vs. non-invasive ventilation for patients with acute exacerbation of COPD after extubation.
13 Sep, 2022 | 13:00h | UTC
Two large clinical trials showed Vitamin D supplements do not reduce the risk of Covid-19.
11 Sep, 2022 | 22:56h | UTCEditorial: Can vitamin D protect against covid-19? – The BMJ
News Release: No link between vitamin D supplements and reduced risk of covid-19 – BMJ Newsroom
Extracorporeal membrane oxygenation during respiratory pandemics: past, present, and future.
11 Sep, 2022 | 22:53h | UTC
International consensus statement on obstructive sleep apnea.
8 Sep, 2022 | 14:41h | UTCInternational consensus statement on obstructive sleep apnea – Allergy & Rhinology (PDF)
Systematic Review | Chest physiotherapy for pneumonia in adults.
8 Sep, 2022 | 14:36h | UTCChest physiotherapy for pneumonia in adults – Cochrane Library
Summary: Chest physiotherapy for pneumonia in adults – Cochrane Library
The Lancet Series | Acute Respiratory Distress Syndrome 2022.
7 Sep, 2022 | 12:37h | UTCHomepage: Acute Respiratory Distress Syndrome 2022 – The Lancet
Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes
Opportunities for improved clinical trial designs in acute respiratory distress syndrome
Addressing the inequity of acute respiratory distress syndrome
Review | Pulse oximetry for the diagnosis and management of acute respiratory distress syndrome.
6 Sep, 2022 | 14:42h | UTC
Systematic Review | Probiotics for preventing acute upper respiratory tract infections.
6 Sep, 2022 | 14:40h | UTCProbiotics for preventing acute upper respiratory tract infections – Cochrane Library
Commentary on Twitter
#probiotics for preventing colds? @CochraneARI looked at 24 studies w 6,950 people.
👍 may be beneficial in preventing at least 1 occurrence of acute upper respiratory tract infection #URTI & likely beneficial in preventing 3 occurrences of URTIs.https://t.co/A6XxrjKKcI pic.twitter.com/mDR3NYLLzQ— The Cochrane Library (@CochraneLibrary) August 24, 2022
Study suggests AI improves chest X-ray interpretation.
6 Sep, 2022 | 14:38h | UTCCommentary: Study Suggests AI Improves Chest X-Ray Interpretation – Diagnostic Imaging
Original Study: Association of Artificial Intelligence–Aided Chest Radiograph Interpretation With Reader Performance and Efficiency – JAMA Network Open
Commentary on Twitter
AI-aided interpretation improves reader performance and efficiency for identifying major thoracic findings on chest radiographs. @MGH_Webster #OpenAccess #Research https://t.co/JdgW55BgL7
— JAMA Network Open (@JAMANetworkOpen) August 31, 2022
RCT | Anatomical segmentectomy vs. standard lobectomy for non-small cell lung cancer up to 2 cm.
6 Sep, 2022 | 14:28h | UTCRelated:
Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Phase 2 RCT | Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease.
6 Sep, 2022 | 14:22h | UTC
Commentary on Twitter
NEW Research—Pirfenidone slowed the rate of decline of FVC over time in patients with RA-ILD*
Being presented at #ERSCongress, ALERT 3 session, Sept 5 from 13:15 BST
From Joshua Solomon & colleagues https://t.co/Nu8wECECdD
*(please check study limitations) pic.twitter.com/IuRxLDZGd9
— The Lancet Respiratory Medicine (@LancetRespirMed) September 5, 2022