Chest Medicine (all articles)
#ESCCongress | In critically ill patients with COVID-19, full-dose anticoagulation reduced thrombotic events but increased the risk of bleeding.
30 Aug, 2022 | 12:12h | UTCNews Release: Trial supports full-dose anticoagulation to prevent blood clots in COVID-19 patients – European Society of Cardiology
Related:
Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library
Commentary on Twitter
#OriginalResearch SimPub #ESCCongress: In the #COVID-PACT 2×2 factorial RCT, full-dose prophylactic anticoagulation, but not the addition of clopidogrel, reduced thrombotic complications but w/ increased bleeding among critically-ill patients w/ COVID-19 https://t.co/UNxFCIC5B9 pic.twitter.com/p5LGmpCGeL
— Circulation (@CircAHA) August 29, 2022
#ESCCongress | 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension.
29 Aug, 2022 | 12:18h | UTCNews Release: Pulmonary hypertension guidelines call for earlier diagnosis – European Society of Cardiology
#ESCCongress – RCT | In comatose survivors of out-of-hospital cardiac arrest, a restrictive vs. a liberal oxygenation strategy resulted in similar incidences of death, severe disability, and coma.
29 Aug, 2022 | 12:12h | UTCOxygen Targets in Comatose Survivors of Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: Restrictive oxygenation in post cardiac arrest patients is not harmful – European Society of Cardiology
Commentary on Twitter
BOX Oxygen: This RCT found no difference in the rate of death or severe disability/coma when mechanically ventilated patients following out-of-hospital cardiac arrest were managed with higher or lower oxygenation targets. #ESCCongress https://t.co/qqtd4SyVrl pic.twitter.com/q73gqSuAn4
— NEJM (@NEJM) August 27, 2022
Meta-analysis of randomized trials | Intensive vs. short face-to-face smoking cessation interventions.
29 Aug, 2022 | 12:03h | UTC
Systematic Review | Pulmonary rehabilitation versus usual care for adults with asthma.
26 Aug, 2022 | 13:12h | UTCPulmonary rehabilitation versus usual care for adults with asthma – Cochrane Library
Commentary on Twitter
Very excited to see our new @CochraneAirways review in print! A modest body of evidence highlights likely benefits of #pulmonaryrehab on ex.tol and QoL in people with #asthma. Big thanks to @EvidSynIRL for supporting @ccass2000's mentorship! Link here: https://t.co/DlgdTqETtb pic.twitter.com/RAtOO0Oam6
— Christian Osadnik (@COsadnik) August 23, 2022
Retrospective Cohort Study | Clinical and genetic risk factors for acute incident venous thromboembolism in ambulatory patients with COVID-19.
24 Aug, 2022 | 14:17h | UTC
Commentary on Twitter
Ambulatory #COVID19 was associated with a substantially increased risk of incident venous thromboembolism, but this risk was greatly reduced in fully vaccinated people with breakthrough infection. https://t.co/98zKNfEWaU #Research
— JAMA Internal Medicine (@JAMAInternalMed) August 18, 2022
Retrospective Cohort Study | Association of COVID-19 vs. Influenza with risk of arterial and venous thrombotic events among hospitalized patients.
24 Aug, 2022 | 14:16h | UTCCommentary: Higher risk of vein blood clots in COVID vs flu patients – CIDRAP
News Release: People with Severe COVID-19 Face Increased Risk of Life-Threatening Blood Clots – Penn Medicine News
Commentary on Twitter
The risk of blood clots in hospitalized patients with Covid vs influenza was increased 60-90% within 90 days, for venous but not arterial thrombosishttps://t.co/wPHf18NYYB @JAMA_current
Retrospective, much smaller influenza cohort from 2018-2019 pic.twitter.com/sClYHF0J6U— Eric Topol (@EricTopol) August 16, 2022
Updated systematic review and critical appraisal: prediction models for diagnosis and prognosis of covid-19.
23 Aug, 2022 | 13:31h | UTCCommentary: Update to living systematic review on prediction models for diagnosis and prognosis of covid-19 – The BMJ
Commentary on Twitter
NEW update in @bmj_latest
606 prognostic models for #COVID19 identified – 29 had low risk of bias, 32 had unclear risk of bias, AND 545 HAD HIGH RISK OF BIAS!
+Poorly reported – use TRIPOD please https://t.co/tVA0xHXdRu#epitwitter #statstwitter pic.twitter.com/n71vdgY8wM
— Gary Collins ?? (@GSCollins) August 22, 2022
RCT | Stopping vs. continuing long-term mepolizumab treatment in severe eosinophilic asthma.
23 Aug, 2022 | 12:55h | UTC
Commentary on Twitter
This randomised study demonstrates increased exacerbation risk and a decrease in asthma control in patients with severe eosinophilic asthma who stop mepolizumab treatment after long-term use, when compared with those who continue treatment. https://t.co/HYCH0TsU9E pic.twitter.com/rW6hmHgJlj
— ERS publications (@ERSpublications) January 6, 2022
Guideline Summary | Recommendations for the outpatient drug treatment of patients with COVID-19.
22 Aug, 2022 | 12:25h | UTC
ATS/ERS/JRS/ALAT Research Statement | Syndrome of combined pulmonary fibrosis and emphysema.
22 Aug, 2022 | 12:12h | UTC
Commentary on Twitter
In this international statement, we propose a research definition of CPFE (for research purposes), +classification criteria of CPFE clinical syndrome for clinicians. Hopefully both will help the field move forward.Thanks to all participants! @ATS_Assemblies @EuroRespSoc @ALATorax https://t.co/PphDomCVJc pic.twitter.com/QLboKM7Tcx
— Vincent Cottin (@OrphaLung) August 18, 2022
RCT | Mepolizumab for urban children with exacerbation-prone eosinophilic asthma.
22 Aug, 2022 | 12:09h | UTCMepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial – The Lancet (link to abstract – $ for full-text)
Commentary: Mepolizumab Cuts Exacerbations in Children With Severe Asthma – HealthDay
Retrospective cohort study | Symptoms and risk factors for long COVID in non-hospitalized adults.
19 Aug, 2022 | 16:17h | UTCSymptoms and risk factors for long COVID in non-hospitalized adults – Nature Medicine
Commentary: UK study finds over 100 symptoms of long COVID in non-hospitalized adults – News Medical
M-A | The accuracy of pulse oximetry in measuring oxygen saturation by levels of skin pigmentation.
19 Aug, 2022 | 16:15h | UTCRelated:
Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine
FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT
Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration
RCT | Metformin, Ivermectin, and Fluvoxamine are not beneficial for obese outpatients with Covid-19.
18 Aug, 2022 | 13:00h | UTCEditorial: Time to Stop Using Ineffective Covid-19 Drugs – New England Journal of Medicine
Commentary on Twitter
In this trial involving overweight or obese outpatients with Covid-19, investigators found that none of three repurposed drugs (metformin, ivermectin, and fluvoxamine) reduced the risk of serious disease. https://t.co/8sd6R7CDK6 pic.twitter.com/bPZ6zeuZSA
— NEJM (@NEJM) August 17, 2022
Pooled analysis of drug-related interstitial lung disease and/or pneumonitis in nine trastuzumab deruxtecan monotherapy studies.
18 Aug, 2022 | 12:47h | UTCCommentaries:
Trastuzumab deruxtecan-related ILD/pneumonitis characterized – medwire News
RCT | Effectiveness of a long-term home-based exercise training program in patients with COPD following pulmonary rehabilitation.
18 Aug, 2022 | 12:43h | UTC
Commentary on Twitter
Effectiveness of a long-term home-based exercise training program in patients with COPD following pulmonary rehabilitation: A multi-center randomized controlled trialhttps://t.co/8u1nizaDNq pic.twitter.com/QwqzN1dDHK
— Physio Meets Science (@PhysioMeScience) August 17, 2022
Under a Creative Commons license
Review | Acute respiratory distress syndrome.
17 Aug, 2022 | 14:30h | UTCAcute Respiratory Distress Syndrome – Emergency Medicine Clinics of North America
Guideline | Use of COVID-19 convalescent plasma.
17 Aug, 2022 | 14:28h | UTC
Risk stratification in patients with acute pulmonary embolism: current evidence and perspectives.
17 Aug, 2022 | 13:55h | UTC
Prolonged mechanical ventilation: outcomes and management.
17 Aug, 2022 | 13:53h | UTCProlonged Mechanical Ventilation: Outcomes and Management – Journal of Clinical Medicine
International clinical practice guidelines for pediatric ventilator liberation.
16 Aug, 2022 | 13:56h | UTC
Study suggests long covid symptoms affect 1 in 8 patients.
16 Aug, 2022 | 13:52h | UTCNews Release: Most reliable estimates to date suggest one in eight COVID-19 patients develop long COVID symptoms – Lancet
Commentaries:
Long COVID symptoms affect 1 in 8 adults, some for 2 years – CIDRAP
Covid-19: One in eight adults develops long covid symptoms, study suggests – The BMJ
UK approves updated Moderna vaccine targeting Omicron variant.
16 Aug, 2022 | 13:49h | UTCUK approves updated Moderna vaccine targeting Omicron variant – Associated Press/MedicalXpress
See also: Covid: UK first country to approve dual-strain vaccine – BBC
Review | Chronic hypercapnic respiratory failure and non-invasive ventilation in people with chronic obstructive pulmonary disease.
16 Aug, 2022 | 13:37h | UTC
Commentary on Twitter
? The latest review on non-invasive ventilation aims to provide background for internists to consider this therapeutic option for their #COPD patients. Read it now ▶️ https://t.co/7mnYMPHKEp#MedTwitter #BMJMedicine #CCFCOPD @CCF_PCCM pic.twitter.com/DfmOZxAIjG
— BMJMedicine (@BMJMedicine) August 5, 2022