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Chest Medicine

RCT | Ivermectin does not improve time to recovery in outpatients with mild to moderate COVID-19.

24 Oct, 2022 | 14:14h | UTC

Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19: A Randomized Clinical Trial – JAMA

Commentary: Ivermectin doesn’t speed time to recovery from nonsevere COVID – CIDRAP

 

Commentary on Twitter

 

RCT | Effect of financial voucher incentives on the cessation of smoking in pregnant women.

21 Oct, 2022 | 12:58h | UTC

Effect of financial voucher incentives provided with UK stop smoking services on the cessation of smoking in pregnant women (CPIT III): pragmatic, multicentre, single blinded, phase 3, randomised controlled trial – The BMJ

Editorial: Financial incentives for sustained smoking abstinence in pregnancy – The BMJ

News Release: Shopping vouchers help women to stop smoking during pregnancy – BMJ Newsroom

 

Commentary on Twitter (thread – click for more)

 

Pooled analysis of cohort studies | Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters.

19 Oct, 2022 | 14:28h | UTC

Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters: pooled analysis of national prospective cohort studies of 30 million individuals in England, Northern Ireland, Scotland, and Wales – The Lancet

Commentaries:

Prioritisation of COVID-19 boosters in the omicron era – The Lancet

COVID booster halved severe illness, but some groups still at higher risk – CIDRAP

 

RCT | Efficacy of BCG vaccination in reducing the incidence and severity of COVID-19 in a high-risk population.

19 Oct, 2022 | 14:26h | UTC

Efficacy of Bacillus Calmette–Guérin (BCG) Vaccination in Reducing the Incidence and Severity of COVID-19 in High-Risk Population (BRIC): a Phase III, Multi-centre, Quadruple-Blind Randomised Control Trial – Infectious Diseases and Therapy

 

Case-control study | Odds of hospitalization for COVID-19 after 3 vs. 2 doses of mRNA vaccine by time since booster dose.

19 Oct, 2022 | 14:27h | UTC

Odds of Hospitalization for COVID-19 After 3 vs 2 Doses of mRNA COVID-19 Vaccine by Time Since Booster Dose – JAMA

News Release: Study indicates COVID-19 boosters among vaccinated individuals significantly reduce hospitalization rates – Providence Health & Services

 

Pneumonia update for emergency clinicians.

19 Oct, 2022 | 14:19h | UTC

Pneumonia Update for Emergency Clinicians – Current Emergency and Hospital Medicine Reports

 

M-A | Endothelin receptor antagonists do not improve outcomes in idiopathic pulmonary fibrosis.

19 Oct, 2022 | 14:14h | UTC

The potential benefit of endothelin receptor antagonists’ therapy in idiopathic pulmonary fibrosis: A meta-analysis of results from randomized controlled trials – Medicine

 

Review | Optimizing PO2 during peripheral veno-arterial ECMO.

19 Oct, 2022 | 14:10h | UTC

Optimizing PO2 during peripheral veno-arterial ECMO: a narrative review – Critical Care

 

Health effects associated with smoking: a Burden of Proof study.

17 Oct, 2022 | 12:36h | UTC

Health effects associated with smoking: a Burden of Proof study – Nature Medicine

See also:

News Release: New star rating system published in Nature Medicine helps people make informed decisions about diet and healthy habits – Institute for Health Metrics and Evaluation

Commentary: Expert reaction to studies presenting a standardized approach for quantifying the strength of evidence that supports associations between risk factors and health outcomes – Science Media Centre

Homepage: The Burden of Proof Studies – Nature Medicine

The Burden of Proof studies: assessing the evidence of risk

Health effects associated with vegetable consumption: a Burden of Proof study

Health effects associated with consumption of unprocessed red meat: a Burden of Proof study

Effects of elevated systolic blood pressure on ischemic heart disease: a Burden of Proof study

 

Commentary on Twitter

 

RCT | Impact of vaping prevention advertisements on adolescents.

14 Oct, 2022 | 13:57h | UTC

Impact of Vaping Prevention Advertisements on US Adolescents: A Randomized Clinical Trial – JAMA Network Open

News Release: Researchers find FDA ‘Real Cost’ ads reduce teen openness to vaping – UNC Lineberger Comprehensive Cancer Center

 

Commentary on Twitter

 

Guideline | Evaluation and management of venous thromboembolism.

12 Oct, 2022 | 13:55h | UTC

Joint Guideline on Venous Thromboembolism – 2022 – Arquivos Brasileiros de Cardiologia

 

Estimated global proportions of persistent fatigue, cognitive, and respiratory symptoms following symptomatic COVID-19.

11 Oct, 2022 | 13:39h | UTC

Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symptom Clusters Following Symptomatic COVID-19 in 2020 and 2021 – JAMA

Commentaries:

Women And Hospitalized Patients More Prone To Long Covid, Study Finds – Forbes

Nearly two-thirds of long COVID patients are female, global study finds – UPI

 

Commentary on Twitter

 

Development of a symptom-based tool for screening of children at high risk of preschool asthma.

11 Oct, 2022 | 13:34h | UTC

Development of a Symptom-Based Tool for Screening of Children at High Risk of Preschool Asthma – JAMA Network Open

News Release: Simple new tool allows primary caregivers to detect young kids at high risk of asthma – McMaster University

 

Commentary on Twitter

 

Extracorporeal membrane oxygenation for cardiogenic shock: a meta-analysis of mortality and complications.

11 Oct, 2022 | 13:33h | UTC

Extracorporeal membrane oxygenation for cardiogenic shock: a meta-analysis of mortality and complications – Annals of Intensive Care

 

M-A | Higher vs. lower oxygenation strategies in the general intensive care unit population.

11 Oct, 2022 | 13:25h | UTC

Higher versus lower oxygenation strategies in the general intensive care unit population: A systematic review, meta-analysis and meta-regression of randomized controlled trials – Journal of Critical Care

Related:

Oxygen targets – Intensive Care Medicine (if the link is paywalled, try this one)

Thoracic Society of Australia and New Zealand Position Statement on Acute Oxygen Use in Adults: ‘Swimming between the flags’ – Respirology

Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia – Intensive Care Medicine

Oxygen Targets During Mechanical Ventilation in the ICU: A Systematic Review and Meta-Analysis – Critical Care Explorations

Effect of Low-Normal vs High-Normal Oxygenation Targets on Organ Dysfunction in Critically Ill Patients: A Randomized Clinical Trial – JAMA

Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine

 

RCT | Riociguat improved hemodynamics but increased dropouts in pulmonary hypertension and HFpEF.

11 Oct, 2022 | 13:26h | UTC

Riociguat in pulmonary hypertension and heart failure with preserved ejection fraction: the haemoDYNAMIC trial – European Heart Journal

 

Commentary on Twitter

Under a https://creativecommons.org/licenses/by-nc/4.0/ license

 

Podcast | Chronic Obstructive Pulmonary Disease (COPD) Update.

6 Oct, 2022 | 13:40h | UTC

#356 Chronic Obstructive Pulmonary Disease (COPD) Update with Dr. Antonio Anzueto – The Curbsiders

 

Systematic Review | Physical activity and exercise training in cystic fibrosis.

3 Oct, 2022 | 13:46h | UTC

Physical activity and exercise training in cystic fibrosis – Cochrane Library

Summary: Physical activity to improve exercise capacity in people with cystic fibrosis – Cochrane Library

 

Commentary on Twitter

 

Cochrane Library | Preoperative exercise training for people with non‐small cell lung cancer.

3 Oct, 2022 | 13:44h | UTC

Preoperative exercise training for people with non‐small cell lung cancer – Cochrane Library

 

Perspective/review | Bronchoscopy for diagnosis of ventilator-associated pneumonia.

30 Sep, 2022 | 12:40h | UTC

Bronchoscopy for diagnosis of ventilator-associated pneumonia – Intensive Care Medicine

 

Review | The many faces of cryptogenic organizing pneumonia.

30 Sep, 2022 | 12:40h | UTC

The many faces of cryptogenic organizing pneumonia (COP) – Journal of Clinical Imaging Science

 

Systematic Review | Increased vs. stable doses of inhaled corticosteroids for exacerbations of asthma in adults and children.

30 Sep, 2022 | 12:30h | UTC

Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children – Cochrane Library

 

RCT | High-flow nasal cannula oxygen did not reduce mortality in patients with respiratory failure due to COVID-19.

28 Sep, 2022 | 13:51h | UTC

Effect of High-Flow Nasal Cannula Oxygen vs Standard Oxygen Therapy on Mortality in Patients With Respiratory Failure Due to COVID-19: The SOHO-COVID Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentary: High-Flow Oxygen Fails to Reduce Mortality due to COVID-19 Respiratory Failure – HCP Live

 

M-A | Combination therapy with long-acting bronchodilators and risk of adverse cardiovascular events in patients with COPD.

28 Sep, 2022 | 13:40h | UTC

Combination therapy with long-acting bronchodilators and the risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis – European Respiratory Journal (link to abstract – $ for full-text)

 

M-A | Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism.

27 Sep, 2022 | 13:07h | UTC

Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis – Thrombosis Research

 

Commentary on Twitter

 

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