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Cardiology (all articles)

M-A: Data from randomized trials showed nonfatal myocardial infarction cannot be established as a good surrogate for all-cause and cardiovascular mortality.

26 Oct, 2021 | 01:36h | UTC

Assessment of Nonfatal Myocardial Infarction as a Surrogate for All-Cause and Cardiovascular Mortality in Treatment or Prevention of Coronary Artery Disease: A Meta-analysis of Randomized Clinical Trials – JAMA Internal Medicine (free for a limited period)

Editorial: Nonfatal Myocardial Infarction—Poor Surrogate for Mortality – JAMA Internal Medicine (free for a limited period)

 

Review: Cardiac involvement in the long-term implications of COVID-19.

24 Oct, 2021 | 23:59h | UTC

Cardiac involvement in the long-term implications of COVID-19 – Nature Reviews Cardiology

 

2021 Interim Guidance to Health Care Providers for Basic and Advanced Cardiac Life Support in Adults, Children, and Neonates With Suspected or Confirmed COVID-19.

24 Oct, 2021 | 23:49h | UTC

2021 Interim Guidance to Health Care Providers for Basic and Advanced Cardiac Life Support in Adults, Children, and Neonates With Suspected or Confirmed COVID-19 – Circulation: Cardiovascular Quality and Outcomes

Commentary: CPR on a COVID Patient: Not a Moment to Waste Looking for PPE: Updated AHA guidance says resuscitation should not be delayed by mask availability – MedPage Today (free registration required)

 

Commentary on Twitter (thread – click for more)

 

RCT: In comatose survivors of out-of-hospital cardiac arrest, there was no difference in mortality and neurologic outcomes with mild (target temperature of 34 °C) vs. moderate therapeutic hypothermia (target temperature of 31 °C).

24 Oct, 2021 | 23:46h | UTC

Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The CAPITAL CHILL Randomized Clinical Trial – JAMA (free for a limited period)

Related:

Cooling After Cardiac Arrest – The Sclerosis of Therapeutic Fashion – “The story of how an ineffective therapy persisted for decades”

RCT: In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not improve outcomes.

Study commentary: a history of hypothermia for cardiac arrest, 2002-2021 (RIP).

M-A: Targeted temperature management following out-of-hospital cardiac arrest – “Routine use of moderate or deep hypothermia in comatose survivors of OHCA may potentially be associated with more harm than benefit”.

 

Commentary on Twitter

 

Middle-aged and older women are being diagnosed with Takotsubo Syndrome more frequently, up to 10 times more often, than younger women or men of any age.

24 Oct, 2021 | 23:43h | UTC

Sex‐ and Age‐Based Temporal Trends in Takotsubo Syndrome Incidence in the United States – Journal of the American Heart Association

News release: Broken heart syndrome is on the rise, especially among older women – American Heart Association

Commentary: ‘Broken heart’ syndrome is on the rise in women – Cedars-Sinai Medical Center

Related:

International Expert Consensus Document on Takotsubo Syndrome

International Registry: 16.6% of Patients with Takotsubo Syndrome Have Underlying Malignancy

Systematic Review: Long-Term Prognosis and Outcome Predictors in Takotsubo Syndrome

Cohort Study: Hospital Readmission Following Takotsubo Syndrome

 

M-A: Diagnostic accuracy of handheld cardiac ultrasound device for assessment of left ventricular structure and function.

22 Oct, 2021 | 10:15h | UTC

Diagnostic accuracy of handheld cardiac ultrasound device for assessment of left ventricular structure and function: systematic review and meta-analysis – Heart

 

Cohort Study: Hypertensive disorders of pregnancy are associated with a 6-fold or higher increased risk of chronic hypertension in the first years following delivery.

21 Oct, 2021 | 09:51h | UTC

Hypertensive disorders of pregnancy and onset of chronic hypertension in France: the nationwide CONCEPTION study – European Heart Journal

Editorial: Impact of hypertensive disorders of pregnancy: lessons from CONCEPTION

 

Commentary on Twitter

 

Review: Athletes and Hypertension.

20 Oct, 2021 | 09:52h | UTC

Athletes and Hypertension – Current Cardiology Reports

 

Things We Do for No Reason: fluid restriction for the management of acute decompensated heart failure in patients with reduced ejection fraction.

20 Oct, 2021 | 10:00h | UTC

Things We Do for No Reason™: Fluid Restriction for the Management of Acute Decompensated Heart Failure in Patients With Reduced Ejection Fraction – Journal of Hospital Medicine (free for a limited period)

 

Commentary on Twitter

 

Another observational study suggests Rivaroxaban is associated with higher rates of gastrointestinal bleeding than other direct oral anticoagulants.

19 Oct, 2021 | 09:47h | UTC

Rivaroxaban Is Associated with Higher Rates of Gastrointestinal Bleeding Than Other Direct Oral Anticoagulants: A Nationwide Propensity Score–Weighted Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Rivaroxaban Again Linked to More Bleeding vs Other DOACs – TCTMD

Related: Gastrointestinal Safety of Direct Oral Anticoagulants: A Large Population-Based Study – Gastroenterology

 

Commentary on Twitter

 

Guideline: Management of anticoagulants and antiplatelet agents in cutaneous surgery.

19 Oct, 2021 | 09:50h | UTC

S3 guideline: Management of anticoagulants and antiplatelet agents in cutaneous surgery – Journal of the German Society of Dermatology

 

Systematic Review: Calcium channel blockers versus other classes of drugs for hypertension – “there is moderate certainty evidence that diuretics reduce major cardiovascular events and congestive heart failure more than CCBs”.

19 Oct, 2021 | 08:56h | UTC

Summary: Calcium channel blockers versus other classes of drugs for hypertension – Cochrane Library

Original Study: Calcium channel blockers versus other classes of drugs for hypertension – Cochrane Library

 

Commentary on Twitter

 

Preoperative hypertension: perioperative implications and management.

19 Oct, 2021 | 08:51h | UTC

Preoperative hypertension: perioperative implications and management – BJA Education

 

Guidelines for anesthesiologists on patient blood management in cardiac surgery.

17 Oct, 2021 | 21:22h | UTC

2021 Clinical Practice Guidelines for Anesthesiologists on Patient Blood Management in Cardiac Surgery – Journal of Cardiothoracic and Vascular Anesthesia

 

Commentary on Twitter

 

Statins linked to reduced risk of death from COVID-19 in major population study – “Randomized studies will be needed to ascertain whether there is a causal relationship, note the researchers”.

15 Oct, 2021 | 02:47h | UTC

News release: Statins linked to reduced risk of death from COVID-19 in major population study – Karolinska Institutet

Original study: HMG-CoA reductase inhibitors and COVID-19 mortality in Stockholm, Sweden: A registry-based cohort study – PLOS Medicine

Commentaries:

Expert reaction to study looking at statins and risk of death from COVID-19 – Science Media Centre

People taking statins less likely to die from Covid, study suggests – The Guardian

 

FDA issues food industry guidance for reduction of sodium in processed and packaged foods.

15 Oct, 2021 | 02:29h | UTC

News Release: To Improve Nutrition and Reduce the Burden of Disease, FDA Issues Food Industry Guidance for Voluntarily Reducing Sodium in Processed and Packaged Foods – U.S. Food & Drug Administration

Guidance for Industry: Voluntary Sodium Reduction Goals – U.S. Food & Drug Administration

Commentaries:

FDA Issues New Guidance on Sodium Targets for Food Industry – TCTMD

Reducing Sodium Intake in the US: Healthier Lives, Healthier Future – JAMA

FDA Reduces Recommended Salt Levels in Americans’ Food – HealthDay

FDA guidance to food industry aims to reduce sodium consumption – American Heart Association

New FDA guidance aims to drastically cut salt in food supply – NBC News

 

Former CDC director: Low sodium salt could save millions of lives.

15 Oct, 2021 | 02:27h | UTC

Former CDC director: Low sodium salt could save millions of lives – CNN

Related:

Is salt good for you after all? The evidence says no.

#ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

Systematic Review: Altered dietary salt intake for people with chronic kidney disease.

New WHO benchmarks help countries reduce salt intake and save lives.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Meta-Analysis: Effect of Reduction in Dietary Sodium on Blood Pressure Levels

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

 

Systematic Review: There is not enough evidence from randomized trials to inform about the effects of additional antihypertensive drugs in patients with hypertension‐induced left ventricular hypertrophy.

15 Oct, 2021 | 02:20h | UTC

Pharmacotherapy for hypertension‐induced left ventricular hypertrophy – Cochrane Library

Summary: What are the main benefits and risks of drugs for reducing blood pressure in the treatment of people with thickening of the heart muscle caused by high blood pressure? – Cochrane Library

 

Commentary on Twitter

 

Meta-analysis of cohort studies: High intake of fatty acid in nuts, seeds and plant oils linked to lower risk of death.

15 Oct, 2021 | 02:22h | UTC

News release: High intake of fatty acid in nuts, seeds and plant oils linked to lower risk of death – The BMJ

Original study: Dietary intake and biomarkers of alpha linolenic acid and risk of all cause, cardiovascular, and cancer mortality: systematic review and dose-response meta-analysis of cohort studies – The BMJ

Commentaries:

Current evidence on dietary intakes of fatty acids and mortality – The BMJ

Expert reaction to systematic review and meta-analysis on consumption of dietary fatty acids (alpha linolenic acid) and risk of death – Science Media Centre

Related: Total dietary fat intake, fat quality, and health outcomes: A scoping review of systematic reviews of prospective studies.

 

Commentary on Twitter

 

Trends in use and outcomes of same-day discharge following elective percutaneous coronary intervention.

15 Oct, 2021 | 02:15h | UTC

Trends in Use and Outcomes of Same-Day Discharge Following Elective Percutaneous Coronary Intervention – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)

Commentaries:

Trends in Same-Day Discharge for Elective PCI – American College of Cardiology

Same-Day Discharge After Elective PCI: No Increases in 30-Day Mortality, Rehospitalization – Physician’s Weekly

 

M-A: Predictors of permanent pacemaker implantation in patients undergoing transcatheter aortic valve replacement.

15 Oct, 2021 | 02:19h | UTC

Predictors of Permanent Pacemaker Implantation in Patients Undergoing Transcatheter Aortic Valve Replacement ‐ A Systematic Review and Meta‐Analysis – Journal of the American Heart Association

 

Commentary on Twitter

 

Cohort study: Among women with congenital Long QT, progestin oral contraceptives were linked to a 2.8-fold increased risk of cardiovascular events in those not receiving B-blocker therapy.

15 Oct, 2021 | 02:17h | UTC

Use of oral contraceptives in women with congenital long QT syndrome – Heart Rhythm (link to abstract – $ for full-text)

Commentary: Progestin OCs Triple CV Events in Women With Congenital Long QT – TCTMD

 

Podcast with Dr Walter Willett: CardioNutrition – Why are findings from prospective, epidemiologic cohort studies important in informing dietary recommendations?

14 Oct, 2021 | 09:49h | UTC

ACC CardiaCast: CardioNutrition – Why Are Findings From Prospective, Epidemiologic Cohort Studies Important In Informing Dietary Recommendations? – American College of Cardiology

 

Commentary on Twitter

 

M-A: Outcomes after transcatheter aortic valve replacement in bicuspid versus tricuspid anatomy – device success and 1-year survival rates are similar, but patients with bicuspid valves have a higher risk for periprocedural complications.

14 Oct, 2021 | 09:51h | UTC

Outcomes After Transcatheter Aortic Valve Replacement in Bicuspid Versus Tricuspid Anatomy: A Systematic Review and Meta-Analysis – JACC: Cardiovascular Interventions

 

USPSTF draft statement revises previous guidance and now recommends against initiating low-dose aspirin use for the primary prevention of CVD in adults aged 60 years or older.

13 Oct, 2021 | 01:36h | UTC

USPSTF Draft Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease – U.S. Preventive Services Task Force

Commentaries:

Advice shifting on aspirin use for preventing heart attacks – Associated Press

Taking aspirin to prevent heart attack may cause more harm than good, task force says – NPR

Related Randomized Trials:

Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease

Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes

Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly

Related Meta-Analysis:

Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events

Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events

Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups – BMC Medicine

Related Opinions:

Aspirin for Primary Prevention: Is This the End of the Road?

Evidence evolving on aspirin as prevention – ACP Internist

 

Commentary on Twitter

 

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