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Brazilian guidelines for the management of brain-dead potential organ donors
17 Dec, 2020 | 09:00h | UTC
Scientists fear that ‘covidization’ is distorting research: Some researchers worry that shifting priorities towards pandemic-focused science comes at the expense of other disciplines.
17 Dec, 2020 | 08:47h | UTCScientists fear that ‘covidization’ is distorting research – Nature
Randomized trial: Dexamethasone for chronic subdural hematoma resulted in fewer favorable outcomes and more adverse events than placebo at 6 months
17 Dec, 2020 | 09:02h | UTCTrial of Dexamethasone for Chronic Subdural Hematoma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Dexamethasone should be avoided in patients with chronic subdural haematoma – University of Cambridge AND Dexamethasone for Chronic Subdural Hematoma? – NEJM Journal Watch
Commentary on Twitter
In a trial that compared a 2-week course of dexamethasone with placebo in patients with a chronic subdural hematoma, a favorable outcome on the modified Rankin scale at 6 months was more common in the placebo group than in the dexamethasone group.
— NEJM (@NEJM) December 17, 2020
Guideline: ADA 2021 Standards of Medical Care in Diabetes
10 Dec, 2020 | 00:11h | UTCJust published! New ADA 2022 Guideline for the Management of Diabetes
Guideline Homepage: ADA 2021 Standards of Medical Care in Diabetes – American Diabetes Association (free supplement)
See ADA 2021 Guideline topics below:
Introduction: Standards of Medical Care in Diabetes—2021
Summary of Revisions: Standards of Medical Care in Diabetes—2021
- Improving Care and Promoting Health in Populations: Standards of Medical Care in Diabetes—2021
- Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2021
- Prevention or Delay of Type 2 Diabetes: Standards of Medical Care in Diabetes—2021
- Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Medical Care in Diabetes—2021
- Facilitating Behavior Change and Well-being to Improve Health Outcomes: Standards of Medical Care in Diabetes—2021
- Glycemic Targets: Standards of Medical Care in Diabetes—2021
- Diabetes Technology: Standards of Medical Care in Diabetes—2021
- Obesity Management for the Treatment of Type 2 Diabetes: Standards of Medical Care in Diabetes—2021
- Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes—2021
- Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes—2021
- Microvascular Complications and Foot Care: Standards of Medical Care in Diabetes—2021
- Older Adults: Standards of Medical Care in Diabetes—2021
- Children and Adolescents: Standards of Medical Care in Diabetes—2021
- Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes—2021
- Diabetes Care in the Hospital: Standards of Medical Care in Diabetes—2021
- Diabetes Advocacy: Standards of Medical Care in Diabetes—2021
Commentary on Twitter
ADA's "Standards of Medical Care in Diabetes—2021" is finally here! Featuring American Diabetes Association's latest clinical practice recommendations, the global standard for diabetes care. #ADASOC2021
📖 READ NOW (OPEN ACCESS): https://t.co/VyIT2yJnW8 pic.twitter.com/vOM5XXKLoU
— ADA Professional Publications (@ADA_Pubs) December 9, 2020
Randomized trial: In small infants, orotracheal intubation assisted with video laryngoscopy improves first-attempt success rate and reduces complications
17 Dec, 2020 | 08:56h | UTCFirst-attempt success rate of video laryngoscopy in small infants (VISI): a multicentre, randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
Fascinating paediatric VL study
VL
-improved FPS (esp <6.5kg)
& reduced
-attempts
-failures
-manipulations
-complications
-severe complicationsThe evidence grows that VL is simply better
Everywherehttps://t.co/f9nj6l2zk3— Tim Cook (@doctimcook) December 11, 2020
Systematic review: “Early or very early pharmacotherapeutic treatment of a hemodynamically significant patent ductus arteriosus probably does not reduce mortality in preterm infants”
17 Dec, 2020 | 08:58h | UTC
Commentary on Twitter (thread – click for more)
So @CochraneNeonate evidence suggest no benefit of early (<7 days) PDA Rx, possible harm: https://t.co/oRc5HlCQ5l
Would our #neoEBM community apply this to <26 wk infants? 113 from across the 🌏 responded (39🇨🇦, 23🇺🇸, 13🇸🇦, 8🇬🇧), and the results are striking! A thread.. @EBNEO— Souvik Mitra (@souvik_neo) December 11, 2020
Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study
16 Dec, 2020 | 09:57h | UTCCommentary: Researchers Say We’re Watching The World Go Blind – Michigan Medicine – University of Michigan
Commentaries on Twitter
Two new studies on the causes and trends of blindness and vision impairment show the world is not meeting targets to reduce avoidable sight loss. Both studies are available online in @LancetGH.
Causes: https://t.co/j0y0poscj1
Trends: https://t.co/DPT8jKLyVx pic.twitter.com/aKxlvqvv2B— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) December 2, 2020
(thread – click for more)
https://twitter.com/DrJSteinmetz/status/1334272298141016069
Comprehensive overview of current pharmacological augmentation recommendations for major depression
17 Dec, 2020 | 08:55h | UTC
Commentary on Twitter
Pharmacological augmentation in unipolar depression – our new review of treatment guidelines compares current recommendations and discusses future guideline development @LindseyMarwood @valeriadeangel @roland_zahn @TCleare @ijnp_neuropsych https://t.co/ui5mGUP8nW
— Rachael Taylor (@rachael_wallis) June 5, 2020
Survey study: Sleep-related impairment among doctors linked to increased clinically significant medical errors
17 Dec, 2020 | 08:53h | UTCCommentaries: Lack of sleep tied to physician burnout, medical errors – MedicalXpress AND Poor Physician Sleep Associated with More Medical Errors – NEJM Journal Watch
Commentary on Twitter
Survey study: sleep-related impairment associated with higher burnout & lower professional fulfillment, as well as independent dose-response association with self-reported physician medical errors. @StanfordMed https://t.co/FPk4tYnDT1
— JAMA Network Open (@JAMANetworkOpen) December 9, 2020
Randomized trial: In surgical patients at moderate or high risk of venous thromboembolism, pharmaco-thromboprophylaxis alone is as good as the combination of pharmaco-thromboprophylaxis and graduated compression stockings
16 Dec, 2020 | 10:00h | UTC
Randomized trial: Extensive peritoneal lavage with saline after curative gastrectomy for gastric cancer does not benefit patients vs. surgery alone
16 Dec, 2020 | 09:55h | UTCExtensive peritoneal lavage with saline after curative gastrectomy for gastric cancer (EXPEL): a multicentre randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
ICYMI – Results of the EXPEL trial show no survival benefit with extensive peritoneal #lavage after surgery vs surgery alone; not recommended for patients undergoing curative #gastrectomy for #gastriccancer.https://t.co/rCgHNt7VZ1#gitwitter #some4surgery pic.twitter.com/BC1BJgElYm
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) December 9, 2020
Observational study suggests we should individualize blood pressure targets among critically ill patients with different ranges of pre-illness baseline mean perfusion pressure
16 Dec, 2020 | 10:01h | UTCCommentary: Personalized Pressors – REACT Study Group – Journal Feed
COVID-19 is 10 times deadlier for people with Down syndrome, raising calls for early vaccination
17 Dec, 2020 | 08:51h | UTC
How a torrent of COVID science changed research publishing — in seven charts
17 Dec, 2020 | 08:48h | UTCHow a torrent of COVID science changed research publishing — in seven charts – Nature
2021: research and medical trends in a post-pandemic world
17 Dec, 2020 | 08:46h | UTC2021: research and medical trends in a post-pandemic world – Nature
Systematic review: Infection and mortality of healthcare workers worldwide from COVID-19
17 Dec, 2020 | 08:40h | UTC
Commentary on Twitter
https://twitter.com/DrSoumyadeepB/status/1335124725576552448
Study: Filtration efficiency of face masks used by the public during the COVID-19 pandemic are, in many cases, nearly equivalent to or better than their non-N95 respirator medical mask counterparts
17 Dec, 2020 | 08:43h | UTCEditorial: Filtration Efficiency of Face Masks Used by the Public During the COVID-19 Pandemic
Commentary on Twitter
Marked reassurance on the value of cloth masks.
A new @JAMAInternalMed assessment today https://t.co/bTrurKeG71 Attention to fit is key, such as aluminum nose bridge, ties, no beard, etc 😷😷 @Phillip_Clapp @UNC_SOM pic.twitter.com/ZCMTT2OWXc— Eric Topol (@EricTopol) December 11, 2020
Individual and community-level risk predictor for COVID-19 mortality in the US, with risk calculator
16 Dec, 2020 | 09:42h | UTCIndividual and community-level risk for COVID-19 mortality in the United States – Nature Medicine
Calculator: Covid-19 risk
Commentary on Twitter
New @NatureMedicine
What is your individualized risk of dying from covid19?https://t.co/Bg61t3raVNhttps://t.co/tQGH0ilsmR (1.1X for me) pic.twitter.com/9pkwyCUAVw— Eric Topol (@EricTopol) December 11, 2020
COVID-19 mimics on chest CT: a pictorial review and radiologic guide
17 Dec, 2020 | 08:37h | UTC
Open-access journal eLife announces ‘preprint first’ publishing model
16 Dec, 2020 | 09:53h | UTCOpen-access journal eLife announces ‘preprint first’ publishing model – Nature
Video (5min): Ivermectin for COVID-19 | A Doctor Explains
16 Dec, 2020 | 09:43h | UTCIvermectin For COVID-19 | A Doctor Explains – ZDoggMD
Nature’s 10: ten people who helped shape science in 2020
16 Dec, 2020 | 09:52h | UTCNature’s 10: ten people who helped shape science in 2020 – Nature
Longer time spent at home during COVID-19 pandemic is associated with binge drinking among US adults
16 Dec, 2020 | 09:36h | UTCCommentaries: New study shows every week of lockdown increases binge drinking – MedicalXpress AND Study finds more binge drinking during stay-at-home lockdowns – MedicalXpress
Increase in overdose-related cardiac arrests observed by emergency medical services during the US COVID-19 epidemic
16 Dec, 2020 | 09:39h | UTCCommentaries: Steady Increase Seen in Cardiac Arrest−Related Overdoses During COVID-19 Pandemic – AJMC AND Sharp rise in overdose deaths during Covid-19 pandemic – MedicalResearch AND Cardiac Arrests Tied to Overdoses Have Surged During the Pandemic – U.S News
Commentary on Twitter
The overdose crisis meets the #COVID19 pandemic: Using data from a large cohort of EMS agencies, @JosephRFriedman @LeoBeletsky and David Schriger observe a nearly 50% increase in EMS-observed cardiac arrests in 2020 as compared to prior years https://t.co/wnsmYfOf7r
— JAMA Psychiatry (@JAMAPsych) December 4, 2020
Study shows rise in childhood depression symptoms during the COVID-19 lockdown
16 Dec, 2020 | 09:41h | UTCCommentaries: Steep rise in depressive symptoms among 7-12 year olds during UK-wide lockdown – British Medical Journal AND Children’s Depression Symptoms Up During U.K. Lockdown – Physician’s Weekly AND Expert reaction to longitudinal study of depression symptoms in children during the COVID-19 lockdown – Science Media Centre