All Posts
Observational study: Childhood growth hormone treatment linked to increased risks of cardiovascular events in early adulthood
10 Jan, 2021 | 20:27h | UTCAssociation of Childhood Growth Hormone Treatment With Long-term Cardiovascular Morbidity – JAMA Pediatrics (link to abstract – $ for full-text)
Commentaries: Childhood Tx with Growth Hormone May Up Cardiovascular Risks Later – Physician’s Weekly AND Growth Hormones in Childhood Tied to Heart Problems Later On – MedPage Today (free registration required)
Axial spondyloarthritis: New advances in diagnosis and management
10 Jan, 2021 | 20:22h | UTCState of the Art Review: Axial spondyloarthritis: new advances in diagnosis and management – The BMJ
Review: Management of Crohn Disease
10 Jan, 2021 | 20:20h | UTCManagement of Crohn Disease: A Review – JAMA (free for a limited period)
Podcast: Crohn Disease Management – JAMA
Guideline Synopsis: Management of patients with a patent foramen ovale with history of stroke or TIA
10 Jan, 2021 | 20:19h | UTCManagement of Patients With a Patent Foramen Ovale With History of Stroke or TIA – JAMA (free for a limited period)
Original Guideline: Practice advisory update summary: Patent foramen ovale and secondary stroke prevention: Report of the Guideline Subcommittee of the American Academy of Neurology – Neurology
Medical errors in the pediatric emergency department: Don’t make these mistakes!
10 Jan, 2021 | 20:21h | UTC
Study suggests that 7 days of home blood pressure monitoring is likely better than 24h ambulatory monitoring or 3 office measurements
10 Jan, 2021 | 20:17h | UTCEditorial: Which Blood Pressure Measurement Best Predicts Cardiovascular Outcomes?
Commentary: Is Home BP Monitoring the Best Approach For Diagnosing HTN? – American College of Cardiology
Meta-analysis: Effectiveness of bundle interventions on ICU delirium
10 Jan, 2021 | 20:16h | UTCEffectiveness of Bundle Interventions on ICU Delirium: A Meta-Analysis – Critical Care Medicine
Commentary: ICU bundles do not appear to improve delirium but may help other outcomes – ACP Hospitalist
Commentary on Twitter
Meta-Analysis incl 11 studies and 26,384 patients for bundle-interventions of delirium treatment showed no effects on delirum duration ( –1.42 d; 95% CI –3.06 to 0.22) or prevalence (risk ratio = 0.92; 95% CI, 0.68–1.24)https://t.co/PzZBGttOL8
— Peter Nydahl (@NydahlPeter) December 18, 2020
NICE Guideline: Managing the long-term effects of COVID-19
18 Dec, 2020 | 10:27h | UTC
Systematic review: Melatonin may have a similar effect to benzodiazepines in reducing preoperative and postoperative anxiety in adults
10 Jan, 2021 | 20:14h | UTCMelatonin for preoperative and postoperative anxiety in adults – Cochrane Library
Summary: Melatonin for preoperative and postoperative anxiety in adults – Cochrane Library
Effects of low sodium diet vs. high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride
10 Jan, 2021 | 20:12h | UTC
NICE Guideline: Do not use Vitamin D to prevent or treat COVID 19
18 Dec, 2020 | 10:03h | UTCCOVID-19 rapid guideline: vitamin D – National Institute for Health and Care Excellence
News release: NICE, PHE and SACN publish rapid COVID-19 guidance on vitamin D
Commentaries: Covid and vitamin D: ‘Not enough evidence’ for treatment – BBC AND Covid-19: Evidence is lacking to support vitamin D’s role in treatment and prevention – The BMJ
Commentary on Twitter
https://twitter.com/onisillos/status/1339485382501666816
Vaccines are here. We have to talk about side effects
18 Dec, 2020 | 09:59h | UTCVaccines Are Here. We Have to Talk About Side Effects – Wired
Commentary on Twitter
All vaccines have side effects and trust comes from freely discussing them. Nice piece by @marynmck https://t.co/eUISXTiFVP
— Madhu Pai, MD, PhD (@paimadhu) December 17, 2020
“Racial Bias in Pulse Oximetry Measurement”. In two large cohorts, Black patients had nearly three times the frequency of occult hypoxemia that was not detected by pulse oximetry as White patients
18 Dec, 2020 | 10:01h | UTCRacial Bias in Pulse Oximetry Measurement – New England Journal of Medicine
Commentary: Devices Used In COVID-19 Treatment Can Give Errors For Patients With Dark Skin – NPR
Commentary on Twitter (thread – click for more)
1/ Our research letter on racial bias in pulse oximetry measurement, out today in NEJM https://t.co/6dLuNGosxp pic.twitter.com/XXsfWfc5dv
— Michael Sjoding (@msjoding) December 17, 2020
COVID 5 times deadlier than flu for hospital patients, study finds
18 Dec, 2020 | 09:53h | UTCCOVID 5 times deadlier than flu for hospital patients, study finds – CIDRAP
Commentary on Twitter
Among people admitted to hospital, #COVID19 was associated with increased risk of various extrapulmonary clinical manifestations, compared with seasonal influenza #BMJResearch https://t.co/R0J9HCvsH2
— The BMJ (@bmj_latest) December 16, 2020
Studies reveal deadliness of COVID-19, even in young adults
18 Dec, 2020 | 09:57h | UTCData reveal deadliness of COVID-19, even in young adults – CIDRAP
Studies warn of COVID vaccine access issues for low-income nations
18 Dec, 2020 | 09:54h | UTCStudies warn of COVID vaccine access issues for low-income nations – CIDRAP
Study 1: Reserving coronavirus disease 2019 vaccines for global access: cross sectional analysis – The BMJ
Editorial: Equitable global access to coronavirus disease 2019 vaccines – The BMJ
Inclusion of pregnant women in COVID-19 treatment trials: a review and global call to action
18 Dec, 2020 | 09:52h | UTCCommentaries: Pregnant women excluded from three-quarters of COVID-19 treatment trials – The Lancet AND Expert reaction to opinion piece on pregnant women and COVID-19 treatment trials – Science Media Centre
Commentary on Twitter (thread – click for more)
NEW—Pregnant women are among those most in need of safe and effective therapies against #COVID19, but are routinely excluded from 3/4 of treatment trials. Read the review published in @LancetGH: https://t.co/xvBfHqnHMe @WHO pic.twitter.com/pBuTcsUZ0O
— The Lancet (@TheLancet) December 17, 2020
Survey: Around 1 in 5 COVID-19 patients exhibit symptoms for a period of 5 weeks or longer; Around 1 in 10 COVID-19 patients exhibit symptoms for a period of 12 weeks or longer
18 Dec, 2020 | 09:49h | UTCThe prevalence of long COVID symptoms and COVID-19 complications – Office of National Statistics
Commentary on Twitter
The prevalence of long COVID symptoms & COVID-19 complications published by @ONS
10% of covid positive patients exhibit symptoms for a period of > 12 weeks
20% for > 5 weeksGreat work by @DanAyoubkhani @Vnafilyan https://t.co/8YgxkCG847
@martinmckee pic.twitter.com/Itizxkk8xC
— Prof Kamlesh Khunti (@kamleshkhunti) December 17, 2020
Neuroimaging manifestations in children with SARS-CoV-2 infection: a multinational, multicenter collaborative study
18 Dec, 2020 | 09:50h | UTCCommentary: Study highlights neurological impact of COVID-19 on children – University of Manchester
Commentary on Twitter (thread – click for more)
New #COVID19 Research: An international call for cases identified 38 children with neurological disease related to #SARSCoV2 infection
Recurring patterns of disease were identified, with #neuroimaging abnormalities ranging from mild to severehttps://t.co/a3bjPlOY0z pic.twitter.com/W0lxLP4aAh
— The Lancet Child & Adolescent Health (@LancetChildAdol) December 16, 2020
2020 ACC/AHA Guideline for the management of patients with valvular heart disease
18 Dec, 2020 | 09:45h | UTCNews release: Updated guideline for heart valve disease spotlights less invasive treatments
Key Perspectives: Part 1
Key Perspectives: Part 2
Key Perspectives: Part 3
Commentary on Twitter
New ACC/@American_Heart Guideline for the Management of patients with #cvVHD includes expanded treatment options; recommends less invasive interventions, when possible; and stresses the importance of #SharedDecisionMaking. Read it in #JACC: https://t.co/g9RE9buXNC pic.twitter.com/jnwt8d5QC7
— JACC Journals (@JACCJournals) December 17, 2020
Publication bias: a problem that leaves us without the full picture on the benefits and harms of treatments
18 Dec, 2020 | 09:37h | UTC
Commentary on Twitter
Publication bias: a problem that leaves us without the full picture on the benefits & harms of treatments https://t.co/ShKZLEiXiv The last blog in @CochraneUK's special series explores why publication bias is so problematic for people making decisions about health care. #OhReally pic.twitter.com/isS1eT4ObZ
— Students4BE (@Students4BE) December 17, 2020
Randomized trial: In kidney transplantation, oxygenated cold perfusion preservation is safe and reduces post-transplant complications compared to standard cold perfusion preservation in kidney transplantation
16 Dec, 2020 | 10:06h | UTCOxygenated versus standard cold perfusion preservation in kidney transplantation (COMPARE): a randomised, double-blind, paired, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Commentary: Oxygenated hypothermic perfusion reduces post-kidney transplant complications – 2 Minute Medicine
CDC Guidelines for Gonococcal Infection, 2020. CDC recommends a single 500 mg intramuscular dose of ceftriaxone for uncomplicated gonorrhea, with oral doxycycline for 7 days when chlamydial coinfection has not been excluded
18 Dec, 2020 | 09:40h | UTCCommentary: CDC Guidelines Recommend Ceftriaxone Monotherapy for Uncomplicated Gonorrhea – NEJM Journal Watch
Commentary on Twitter
https://twitter.com/GarrettHile/status/1339732944613720064
Meta-analysis: Lung cancer screening using low-dose computed tomography reduces lung cancer–specific mortality, albeit with a tradeoff of likely overdiagnosis
16 Dec, 2020 | 10:08h | UTC
ACG Clinical Guideline: Management of irritable bowel syndrome
16 Dec, 2020 | 10:09h | UTC