All Posts
Acute Pancreatitis: A Review
28 Jan, 2021 | 01:20h | UTCAcute Pancreatitis: A Review – JAMA (free for a limited period)
Podcast: Acute Pancreatitis Part 1 of 2: Diagnosis
Podcast: Acute Pancreatitis Part 2 of 2: Treatment
Meta-analysis: Beta-blockers for traumatic brain injury
28 Jan, 2021 | 01:18h | UTCBeta-blockers for traumatic brain injury: a systematic review and meta-analysis – Journal of Trauma and Acute Care Surgery (link to abstract – $ for full-text)
Randomized trial: Prostate-only versus whole-pelvic radiation therapy in high-risk and very high-risk prostate cancer
28 Jan, 2021 | 01:09h | UTC
Commentary on Twitter
🚨 POP-RT P3 RCT in @ASCO_pubs
High-risk prostate cancer & pelvic LN risk ≥20% ➡️
-Prostate only
-Pelvic RTIG-IMRT w/ SIB
-50 Gy/25 fxn to Pelvis
-68 Gy to P+SV⬆️bFFS 95% v 81%
⬆️DFS ~90% v 77%
⬆️DMFS 96% v 89%
✅Low S/Ehttps://t.co/r6YjqWl8Cr#pcsm #radonc #oncoalert pic.twitter.com/d9EL02edcd— Mudit Chowdhary, MD (@DrChowdharyMD) January 27, 2021
ASCO Guideline Update: Initial management of noncastrate advanced, recurrent, or metastatic prostate cancer
28 Jan, 2021 | 01:17h | UTC
Covid-19: Cough, fatigue, sore throat ‘more common’ in new variant
28 Jan, 2021 | 01:41h | UTCCovid-19: Cough, fatigue, sore throat ‘more common’ in new variant – BBC
[Preprint] Efficacy of Colchicine in Non-Hospitalized Patients with COVID-19
28 Jan, 2021 | 01:49h | UTCEfficacy of Colchicine in Non-Hospitalized Patients with COVID-19 – medRxiv
Commentary on Twitter
The large colchicine RCT for covid is preprint published.
It shows some consistent directional benefit for major outcomeshttps://t.co/gxtyKnMqZ5
Since this is a pill, it's safe, cheap & an early intervention (as tested here, before hospital) these findings are very encouraging pic.twitter.com/uzTSkjftFp— Eric Topol (@EricTopol) January 27, 2021
Duration of culturable SARS-CoV-2 in hospitalized patients with Covid-19
28 Jan, 2021 | 01:47h | UTC
Editorial: Covid-19 controversies: the Tocilizumab chapter
28 Jan, 2021 | 01:46h | UTCCovid-19 controversies: the tocilizumab chapter – The BMJ
Related: Contradicting earlier trials, Tocilizumab did not improve outcomes, with signs of harm, in patients with severe Covid-19 (studies and commentaries)
4 reasons we’re seeing these worrying coronavirus variants now – Covid-19 is evolving. Why now?
28 Jan, 2021 | 01:33h | UTC4 reasons we’re seeing these worrying coronavirus variants now – Vox
Global analysis suggests COVID-19 is seasonal
28 Jan, 2021 | 01:45h | UTCGlobal analysis suggests COVID-19 is seasonal – University of Illinois
Original study: Temperature and Latitude Correlate with SARS-CoV-2 Epidemiological Variables but not with Genomic Change Worldwide – Evolutionary Bioinformatics
COVID-19 increases mortality rate among pregnant women
28 Jan, 2021 | 01:32h | UTCCOVID-19 increases mortality rate among pregnant women – University of Washington
Resurgence of COVID-19 in Manaus, Brazil, despite high seroprevalence
28 Jan, 2021 | 01:42h | UTCResurgence of COVID-19 in Manaus, Brazil, despite high seroprevalence – The Lancet
Commentary on Twitter
How could there be a surge of covid-19 in Manaus, Brazil, where ~75% of the population (≥ level of herd immunity) had already been infected?https://t.co/IGMzke7cWE @TheLancet
Analysis of 4 possible explanations implicates the P.1 (and newly described P.2) variants pic.twitter.com/w0q11QQrzU— Eric Topol (@EricTopol) January 28, 2021
Long Covid: Respiratory and psychophysical sequelae among patients with COVID-19 four months after hospital discharge
28 Jan, 2021 | 01:31h | UTCCommentary: Lung, mobility problems plague COVID-19 patients months after recovery – UPI
Low-dose aspirin may improve pregnancy chances for women with one or two prior miscarriages
27 Jan, 2021 | 01:09h | UTCOriginal study: The Effect of Preconception-Initiated Low-Dose Aspirin on Human Chorionic Gonadotropin–Detected Pregnancy, Pregnancy Loss, and Live Birth: Per Protocol Analysis of a Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Summary for Patients: The Effect of Preconception-Initiated Low-Dose Aspirin on Human Chorionic Gonadotropin–Detected Pregnancy, Pregnancy Loss, and Live Birth – Annals of Internal Medicine
Related (study and commentaries): Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): a randomised, double-blind, placebo-controlled trial – The Lancet
Pregnancy, breastfeeding and the SARS-CoV-2 vaccine: an ethics-based framework for shared decision-making
28 Jan, 2021 | 01:29h | UTCCommentary: Offer COVID-19 vaccines to pregnant or breastfeeding people – Canadian Medical Association Journal
AHA Statement: Psychological health, well-being, and the mind-heart-body connection
27 Jan, 2021 | 01:11h | UTCNews release: Mental health is important to overall health, and heart disease prevention and treatment – American Heart Association
Commentary: The head is connected to the heart – and can influence health – American Heart Association
Meta-analysis: Minimally invasive surgery versus transcatheter aortic valve replacement
27 Jan, 2021 | 01:00h | UTCCommentary: TAVI vs Minimally Invasive AVR Yields Surprising Findings: Meta-analysis – TCTMD
Commentary on Twitter
Comprehensive systematic review and meta-analysis of miniAVR vs #TAVR. Important in the context of 'lifetime management of valves'. Thank you for the opportunity. @Shoukmed @ahmedsayed8991 @BrighamSurgery @BrighamThoracic CC:@TSRA_official @STS_CTsurgery @AATSED @ThoracicsCanada https://t.co/T1XDrebl8U pic.twitter.com/5E5eOLherA
— Sameer Hirji (@Hirji1987) January 21, 2021
Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases
27 Jan, 2021 | 01:08h | UTCVitamin D, Calcium, Other Vitamins, and Supplements Do Not Prevent CVD – TCTMD
Original study 1: Vitamin D, Calcium Supplements, and Implications for Cardiovascular Health: JACC Focus Seminar – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Original study 2: Vitamin D, Calcium Supplements, and Implications for Cardiovascular Health: JACC Focus Seminar – Journal of the American College of Cardiology (link to abstract – $ for full-text)
RCT: In a population with a high prevalence of Rheumatic Heart Disease, screening schoolchildren with echocardiography can enable timely initiation of secondary antibiotic prophylaxis
27 Jan, 2021 | 01:05h | UTCCommentaries: Echo Screening for Rheumatic Heart Disease in Kids Gets a Boost – TCTMD
Editorial: Screening for Rheumatic Heart Disease—Quo Vadis?
Author interview: Systematic Echocardiographic Screening for Rheumatic Heart Disease in Nepalese Schoolchildren – JAMA
Commentary on Twitter
RHD accounts for the highest number of deaths due to #VHD worldwide. Cluster RCT in Nepal indicates effectiveness of early detection of clinically silent #RHD by echocardiographic screening of schoolchildren and timely initiation of secondary prophylaxis https://t.co/gCCt4LzV7X
— JAMA Cardiology (@JAMACardio) January 20, 2021
https://twitter.com/ThomPilgrim/status/1352028977519583235
DEVT, SKIP Trials Add Support for Omitting IV tPA Before Stroke Thrombectomy
27 Jan, 2021 | 01:01h | UTCDEVT, SKIP Trials Add Support for Omitting IV tPA Before Stroke Thrombectomy – TCTMD
Original studies and commentaries: Randomized trial: Endovascular treatment alone noninferior to intravenous alteplase plus endovascular treatment on functional independence in patients with acute ischemic stroke
CDC: One in five people in U.S. has a sexually transmitted infection
27 Jan, 2021 | 00:58h | UTCCDC: One in five people in U.S. has a sexually transmitted infection – UPI
Original study: Sexually Transmitted Infections Among US Women and Men: Prevalence and Incidence Estimates, 2018 – Sexually Transmitted Diseases
Position Paper: Composition, structure, and function of heart teams
27 Jan, 2021 | 00:57h | UTC
Meta-analysis of observational studies: Fried-food consumption linked to increased risk of cardiovascular disease and all-cause mortality
27 Jan, 2021 | 00:55h | UTCCommentaries: Fried food intake linked to heightened serious heart disease and stroke risk – The BMJ AND Expert reaction to study looking at fried food and heart disease and stroke risk – Science Media Centre
Systematic review: Payment methods for healthcare providers working in outpatient healthcare settings
27 Jan, 2021 | 00:56h | UTCSummary: Payment methods for healthcare providers in outpatient healthcare settings – Cochrane Library
Commentary on Twitter
Payment methods for #healthcare providers in #outpatient healthcare settings https://t.co/wY6LKEmhbZ New @CochraneEPOC systematic review w evidence from 27 studies suggests that different payment methods can affect healthcare provider behaviour in both positive and negative ways.
— Cochrane (@cochranecollab) January 21, 2021
CDC Report: Low risk of COVID-19 transmission in schools with precautions in place
27 Jan, 2021 | 01:25h | UTCRelated viewpoint: Data and Policy to Guide Opening Schools Safely to Limit the Spread of SARS-CoV-2 Infection – JAMA
Commentary on Twitter
Important study:
While covid test + rates ranged from 7 to 40% in the community, K-12 schools were able to open with nearly no transmission linked to school.The harm of school closure will tear the fabric of society; these steps are worth it to reopen. https://t.co/q0SXpqJrqw pic.twitter.com/rsL7EkVsZZ
— Vinay Prasad MD MPH (@VPrasadMDMPH) January 26, 2021