All Posts
Cohort study: Recovery of consciousness and functional outcome in moderate and severe traumatic brain injury
2 Mar, 2021 | 01:34h | UTCRecovery of Consciousness and Functional Outcome in Moderate and Severe Traumatic Brain Injury – JAMA Neurology (free for a limited period)
Editorial: Holding Out Hope After Traumatic Brain Injury (free for a limited period)
Commentary on Twitter
In this study in @JAMANeuro:
most individuals who became comatose after moderate/severe traumatic brain injury recovered consciousness and ~50% regained functional independence, cautioning early decisions to withdraw/withhold treatment in these patients. https://t.co/jIz38AwCXO— Saleh Almenawer, MD (@SalehAlmenawer) March 1, 2021
Cohort study: Association between preterm-birth phenotypes and differential morbidity, growth, and neurodevelopment at age 2 years
2 Mar, 2021 | 01:41h | UTC
Teleneurology-enabled determination of death by neurologic criteria after cardiac arrest or severe neurologic injury
2 Mar, 2021 | 01:32h | UTCTeleneurology-Enabled Determination of Death by Neurologic Criteria After Cardiac Arrest or Severe Neurologic Injury – Neurology (link to abstract – $ for full-text)
RCT: Prescribed light exercise vs. standard management for emergency department patients with acute mild traumatic brain injury
2 Mar, 2021 | 01:30h | UTCA randomized trial comparing prescribed light exercise to standard management for emergency department patients with acute mild traumatic brain injury – Academic Emergency Medicine (link to abstract – $ for full-text)
Commentary: Exercise After Concussion in Adults? – Journal Feed
Laparoscopic Roux-en-Y gastric bypass vs. laparoscopic sleeve gastrectomy: 5-year outcomes of merged data from two randomized clinical trials
2 Mar, 2021 | 01:27h | UTCVisual abstract: Merged SLEEVEPASS and SM-BOSS trials
M-A: Umbilical cord management at term and late preterm birth
2 Mar, 2021 | 01:25h | UTCUmbilical Cord Management at Term and Late Preterm Birth: A Meta-analysis – Pediatrics (link to abstract – $ for full-text)
To beta-amyloid or not to beta-amyloid? An innovative meta-analysis offers new insight into Alzheimer’s drugs
2 Mar, 2021 | 01:18h | UTCOriginal study: Effect of reductions in amyloid levels on cognitive change in randomized trials: instrumental variable meta-analysis – The BMJ
Commentary on Twitter
https://twitter.com/artwalaszek/status/1365098101845987328
Phase 3 Trials of Tirbanibulin Ointment for Actinic Keratosis
2 Mar, 2021 | 01:24h | UTCPhase 3 Trials of Tirbanibulin Ointment for Actinic Keratosis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
The tubulin polymerization and Src kinase inhibitor tirbanibulin was superior to placebo ointment in clearing actinic keratoses on the face and scalp at 2 months. As is typical of the disorder, lesions recurred in 47% of patients at 1 year.
— NEJM (@NEJM) February 17, 2021
RCT: 3-Year outcomes of transcatheter mitral valve repair in patients with heart failure
2 Mar, 2021 | 01:20h | UTC3-Year Outcomes of Transcatheter Mitral Valve Repair in Patients With Heart Failure – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: 3-Year Outcomes of Transcatheter Mitral Valve Repair in Heart Failure – American College of Cardiology
Cancer replaces heart disease and stroke as the leading cause of death among people with diabetes
2 Mar, 2021 | 01:22h | UTC
Consensus guidelines for botulinum toxin therapy: general algorithms and dosing tables for dystonia and spasticity
2 Mar, 2021 | 01:16h | UTC
Systematic review: Walking for hypertension
2 Mar, 2021 | 01:14h | UTCWalking for hypertension – Cochrane Library
Summary: The effect of walking on blood pressure control – Cochrane Library
Systematic Review: Belimumab for systemic lupus erythematosus
2 Mar, 2021 | 01:11h | UTCBelimumab for systemic lupus erythematosus – Cochrane Library
CDC Report: Reduction in severe COVID-19 following the implementation of a national vaccination program in Israel
28 Feb, 2021 | 21:54h | UTCCommentary: Israeli data suggest mass vaccinations led to drop in severe Covid cases, CDC study finds – CNBC
Commentary on Twitter
A new @CDCMMWR from Israel shows preliminary evidence of the effectiveness of vaccination in preventing severe cases of #COVID19. Vaccination among people who are eligible to receive a COVID-19 vaccine can potentially reduce severe disease from COVID-19. https://t.co/CaUAXRVaS4 pic.twitter.com/GyaulMONpZ
— CDC (@CDCgov) February 26, 2021
Systematic review: Comparison of paravertebral anesthesia vs. general anesthesia for breast cancer surgery
2 Mar, 2021 | 01:12h | UTC
M-A: Treatment with convalescent plasma is not associated with better outcomes in patients with Covid-19
28 Feb, 2021 | 21:51h | UTCEditorial: Emerging Lessons From COVID-19 for the US Clinical Research Enterprise
Commentary on Twitter
Just out: Our meta-analysis in @JAMA_current
"Among patients with COVID-19, treatment with convalescent plasma compared with control was not associated with improved survival or other positive clinical outcomes"https://t.co/tRqpd9v67m
— Lars G. Hemkens (@LGHemkens) February 26, 2021
CDC Study: Suspected SARS-CoV-2 reinfections in a skilled nursing facility
28 Feb, 2021 | 21:55h | UTCCommentaries: Possible SARS-CoV-2 Reinfection Described at Skilled Nursing Facility – HealthDay AND Reinfections could be more likely among those with a mild first case of COVID-19: case study – CTV News
Commentary on Twitter (thread – Click for more)
📌CDC report: Asymptomatic or mildly symptomatic infections don't always produce sufficient immune response to prevent reinfection. Report of nursing facility found 5 people reinfected ~3 months after initial infection. All 5 had more severe symptoms 2nd time around, one death🧵 pic.twitter.com/m9ix9XJolA
— Dr. Ali Nouri (@AliNouriPhD) February 28, 2021
Short Review: SARS-CoV-2 Vaccines
28 Feb, 2021 | 21:52h | UTCAuthor interview: Coronavirus Vaccines—An Overview
Check out the Table ins this #SARSCoV2 Vaccine Overview – everything you wanted to know about upcoming vaccines – Oxford/AZ, Sputnik, Sinovac, more! https://t.co/TWbgfSKBIP
— JAMA (@JAMA_current) February 26, 2021
Studies: Single dose of vaccine acts as ‘booster’ in those with prior COVID-19 infection
28 Feb, 2021 | 21:49h | UTCStudy 1: Antibody response to first BNT162b2 dose in previously SARS-CoV-2-infected individuals – The Lancet
Commentary on Twitter (thread – click for more)
New on 1-dose @Pfizer vaccine after prior covid
"We show that individuals with previous #SARSCoV2 infection generate strong humoral and cellular responses to one dose of BNT162b2 vaccine, with evidence of high titres of in-vitro live virus neutralisation"https://t.co/2G7TRu57OI pic.twitter.com/sIdB0VarqB— Eric Topol (@EricTopol) February 25, 2021
Identification of 3 clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19
28 Feb, 2021 | 21:45h | UTCInvited Commentary: Anticipating outcomes for patients with COVID-19 and identifying prognosis patterns
Commentary on Twitter
Identification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19 https://t.co/kLtzmF5ZWI 📣 These results might help to better classify patients for clinical management #COVID@SPAIN #COVID@HULP pic.twitter.com/ZVaMuUDfnL
— Alberto M. Borobia (@borobia_am) February 24, 2021
Spain to give just one vaccine dose to under 55-year olds who had COVID-19
28 Feb, 2021 | 21:47h | UTCSpain to give just one vaccine dose to under 55-year olds who had COVID-19 – Reuters
Related: Is One Vaccine Dose Enough After COVID-19 Infection? – NIH Director’s Blog AND France’s health authority recommends single vaccine shot for people who have had COVID-19
Long Read | 5 Pandemic Mistakes We Keep Repeating
28 Feb, 2021 | 21:43h | UTC5 Pandemic Mistakes We Keep Repeating – The Atlantic (a few articles per month are free)
Editorial | Twenty Lessons from 2020: With a Focus on the ICU Perspective
28 Feb, 2021 | 21:44h | UTCTwenty Lessons from 2020: With a Focus on the ICU Perspective – ICU Management & Practice
New report reviews methods for reducing waste, improving efficiency with expensive injectable medications
28 Feb, 2021 | 21:29h | UTCOriginal report: Medications in Single Dose Vials: Implications of Discarded Drugs (2021) – National Academies of Sciences, Engineering, and Medicine
Commentary on Twitter
"significant amounts of expensive injectable or infused drugs, distributed in single-dose vials, are discarded" but hard to quantify.
Medications in Single-Dose Vials and Implications of Discarded Injectable Drugs: A National Academies Report https://t.co/z3ebKGIcEg
— Suresh Nirody – snirody.eth (@snirody) February 26, 2021
2 Case Series and Guidance| Lymphadenopathy in COVID-19 Vaccine Recipients
28 Feb, 2021 | 21:42h | UTCCase series: Lymphadenopathy in COVID-19 Vaccine Recipients: Diagnostic Dilemma in Oncology Patients – Radiology
Related case series in women without cancer: Coronavirus Disease (COVID-19) Vaccination Associated Axillary Adenopathy: Imaging Findings and Follow-Up Recommendations in 23 Women – American Journal of Roentgenology
Related guidance 1: Multidisciplinary Recommendations Regarding Post-Vaccine Adenopathy and Radiologic Imaging: Radiology Scientific Expert Panel – Radiology
Related guidance 2: Mitigating the Impact of Coronavirus Disease (COVID-19) Vaccinations on Patients Undergoing Breast Imaging Examinations: A Pragmatic Approach – American Journal of Roentgenology AND Commentary: What to do when a mammogram shows swollen lymph nodes in women just vaccinated for COVID – Massachusetts General Hospital
Commentary: COVID-19 vaccine affects imaging results, researchers warn – AuntMinnie (free registration required)