All Posts
Systematic review: Aldosterone antagonists for people with chronic kidney disease requiring dialysis
3 Mar, 2021 | 08:27h | UTCAldosterone antagonists for people with chronic kidney disease requiring dialysis – Cochrane Library
RCT: Effect of Blinatumomab vs. Chemotherapy in children with high-risk first-relapse B-Cell Acute Lymphoblastic Leukemia
3 Mar, 2021 | 08:19h | UTCEffect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA (free for a limited period)
Related study: Effect of Postreinduction Therapy Consolidation With Blinatumomab vs Chemotherapy on Disease-Free Survival in Children, Adolescents, and Young Adults With First Relapse of B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Blinatumomab for Treatment of Children With High-risk Relapsed B-Cell Acute Lymphoblastic Leukemia – JAMA (free for a limited period)
Chronic suppurative otitis media: Cochrane evidence on treatment options
3 Mar, 2021 | 08:26h | UTC
RCT: Omega-3 supplements do not reduce cardiovascular events in elderly patients after myocardial infarction
3 Mar, 2021 | 08:13h | UTCEffects of n-3 Fatty Acid Supplements in Elderly Patients After Myocardial Infarction: A Randomized, Controlled Trial – Circulation (link to abstract – $ for full-text)
Commentary: Omega-3 fatty acids did not reduce risk of cardiac events in elderly heart attack survivors – News Medical
Commentary on Twitter
OMEMI: In RCT of elderly patients with a recent acute myocardial infarction, n-3 fatty acid supplementation did not reduce clinical events. Read more: https://t.co/nGs5DGGtmT #AHAJournals @Oslounivsykehus @UniOslo @pmyhre @AAKalstad pic.twitter.com/I3Gr89ztyj
— Circulation (@CircAHA) February 11, 2021
M-A: Role of Cilostazol in prevention of vasospasm following aneurysmal subarachnoid hemorrhage
3 Mar, 2021 | 08:16h | UTCRole of Cilostazol in prevention of vasospasm following aneurysmal subarachnoid hemorrhage – A systematic review, meta-analysis and trial sequential analysis – World Neurosurgery (link to abstract – $ for full-text)
The predicative clinical features associated with chronic cough that has a single underlying cause
3 Mar, 2021 | 08:14h | UTCNews release: Clinical features for indicating causes of chronic cough – American Academy of Allergy, Asthma & Immunology
Five-year outcomes from randomized, phase III trials: Nivolumab vs. Docetaxel in previously treated non–small-cell lung cancer
3 Mar, 2021 | 08:10h | UTC
Commentary on Twitter
At 5 years of follow up in CheckMate 017 and 057 trials, nivolumab continues to demonstrate a survival benefit vs docetaxel in patients with previously-treated advanced NSCLC https://t.co/oswZhdAPTW #JCO #lcsm #immunoonc pic.twitter.com/4FZJlfig99
— Journal of Clinical Oncology (@JCO_ASCO) February 9, 2021
Another study shows higher antibody titer responses to a single dose of mRNA vaccine among patients with previous COVID-19 infection
2 Mar, 2021 | 02:13h | UTCRelated: Studies: Single dose of vaccine acts as ‘booster’ in those with prior COVID-19 infection (studies and commentary)
RCT: Extended vs. limited pelvic lymph node dissection during radical prostatectomy for intermediate- and high-risk prostate cancer
3 Mar, 2021 | 08:05h | UTCExtended Versus Limited Pelvic Lymph Node Dissection During Radical Prostatectomy for Intermediate- and High-risk Prostate Cancer: Early Oncological Outcomes from a Randomized Phase 3 Trial – European Urology (link to abstract – $ for full-text)
Commentary: Extended pelvic lymph node dissection during RP does not appear beneficial – Urology Times
Commentary on Twitter
Extended Versus Limited Pelvic Lymph Node Dissection During Radical Prostatectomy for Intermediate- and High-risk Prostate Cancer: Early Oncological Outcomes from a Randomized Phase 3 Trial#VisualAbstract https://t.co/7fAFlKmfTf@jeanlestingi @qdtrinh @RafaelFCoelho2 pic.twitter.com/es53WpXBFR
— European Urology (@EUplatinum) December 10, 2020
M-A: Local salvage therapies after radiotherapy for prostate cancer
3 Mar, 2021 | 08:06h | UTCA Systematic Review and Meta-analysis of Local Salvage Therapies After Radiotherapy for Prostate Cancer (MASTER) – European Urology (link to abstract – $ for full-text)
Commentary on Twitter (thread – click for more)
Pleased to share the results of our "MASTER" systematic review and meta-analysis of local salvage therapies for radioreccurent PCa @EUPlatinum https://t.co/23hy1UtNm5
— Amar Kishan (@AmarUKishan) December 11, 2020
WHO: Roadmap to improve and ensure good indoor ventilation in the context of COVID-19
2 Mar, 2021 | 02:15h | UTC
Commentary on Twitter
Wonderful guidance from @WHO on ventilation. Here are a couple of pages for non-residential settings. All the things we've been talking about: minimum 10 L/s/person, open doors & windows for cross-ventilation, use exhaust fans, filtration. https://t.co/umMzhiqKza pic.twitter.com/UEZLahi87v
— Linsey Marr https://www.threads.net/@linseycmarr (@linseymarr) March 1, 2021
Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children
2 Mar, 2021 | 02:11h | UTCAcute covid-19 and multisystem inflammatory syndrome in children – The BMJ
Commentary on Twitter
The most common symptoms in children with acute SARS-CoV-2 infection are fever and cough. This Clinical Update looks at the presentation of SARS-CoV-2 infection in children, transmission dynamics, and multisystem inflammatory disease @asicksamuelshttps://t.co/XrDtAhJUb9
— The BMJ (@bmj_latest) March 1, 2021
Studies: Secondary infections in patients with severe COVID-19
2 Mar, 2021 | 02:05h | UTCSecondary Infections in Patients with Severe COVID-19 – NEJM Journal Watch
Scaling up COVID-19 rapid antigen tests: promises and challenges
2 Mar, 2021 | 02:09h | UTCScaling up COVID-19 rapid antigen tests: promises and challenges – The Lancet Infectious Diseases
Review: Cardiovascular biomarkers in patients with COVID-19
2 Mar, 2021 | 02:07h | UTC
Commentary on Twitter
Cardiovascular #biomarkers in patients with #COVID19 – review article by @escardio Study Group on Biomarkers in Cardiology of the Acute Cardiovascular Care Association #ACVC_ESC https://t.co/9Mcx24fX8y#EHJACVC #cardiotwitter #medtwitter pic.twitter.com/y7kD2Oylrj
— European Society of Cardiology Journals (@ESC_Journals) March 1, 2021
Serious bradycardia and Remdesivir for COVID-19: a new safety concern
2 Mar, 2021 | 02:06h | UTC
Commentary on Twitter
⛔A new safety concern⛔
New 🔥 post-marketing study @CMIJournal suggests that the use of remdesivir is significantly associated with an increased risk of reporting serious bradycardia compared with HCQ,LPV/RTV, tocilizumab or glucocorticoids #IDTwitter https://t.co/npLMchifEM— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) February 27, 2021
Systematic Review: Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19
2 Mar, 2021 | 01:54h | UTCSummary: Can symptoms and medical examination accurately diagnose COVID-19? – Cochrane Library
We’ve updated our review on signs and symptoms for diagnosing Covid-19. Now includes evidence on loss of smell or taste #redflag @deeksj @leeflang_m @devymaye @SabineDittrich @jacdinnes https://t.co/P4hBbuL0x9
— Ann Van den Bruel (@annvdbruel) February 24, 2021
Consensus Document: Venous thromboembolism prophylaxis in the trauma intensive care unit
2 Mar, 2021 | 01:52h | UTC
Vaccinating the oldest against COVID-19 saves both the most lives and most years of life
2 Mar, 2021 | 02:04h | UTCCommentary: Vaccinating Oldest First for COVID Saves the Most Lives: Study – HealthDay
Commentary on Twitter
The policy of vaccinating the oldest vs covid-19:
Most lives saved and most years of life saved, the latter representing an unexpected extent of life expectancy gainhttps://t.co/KgLrl1j2xt @PNASNews by @jrgoldstein1 and colleagues pic.twitter.com/4MWZRa1i11— Eric Topol (@EricTopol) February 25, 2021
Guideline: Treatment of methicillin-resistant Staphylococcus aureus (MRSA)
2 Mar, 2021 | 01:50h | UTC
Commentary on Twitter
We're delighted to publish the first update of UK #MRSA guidelines in more than a decade. Please share with your contacts & colleagues .
Treatment of methicillin-resistant Staphylococcus aureus (MRSA): updated guidelines from the UKhttps://t.co/3o3OVIdLuB #JACAMRNews #IDtwitter pic.twitter.com/GGlv1C1T1g
— JAC-AMR (@jac_amr) February 4, 2021
Who gets a COVID-19 vaccine and who pays? The need for economic analysis
2 Mar, 2021 | 02:02h | UTC
Commentary on Twitter
NEW from @CGDev and @idsihealth — experts look at the potential of Health Technology Assessment (HTA) on informing how much #COVID19 vaccine countries should buy, who should pay, and how vaccines can be most effectively delivered.
Read: https://t.co/KuMZSARSEF #GlobalHealth
— Center for Global Development (@CGDev) February 24, 2021
Fruit and Vegetable Intake and Mortality: Results From 2 Prospective Cohort Studies of US Men and Women and a Meta-Analysis of 26 Cohort Studies
2 Mar, 2021 | 01:44h | UTCNews release: The right ‘5-a-day’ mix is 2 fruit and 3 vegetable servings for longer life – American Heart Association
Systematic review: Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge
2 Mar, 2021 | 01:46h | UTC
Commentary on Twitter
“Direct oral challenge safe & effective for de-labelling patients at low risk for true allergy. Important for optimizing patient care and tackling #AMR” https://t.co/S3VL8JXyFJ #JACAMRNews #AMR #AMS @SAPGAbx @lac_cooper @jenny_harbour @raseaton66 @jacquisneddons pic.twitter.com/SwE1yyVr8d
— JAC-AMR (@jac_amr) February 23, 2021
RCT: Similar outcomes with intermittent vs. continuous pulse oximetry in hospitalized infants with stabilized bronchiolitis
2 Mar, 2021 | 01:42h | UTCIntermittent vs Continuous Pulse Oximetry in Hospitalized Infants With Stabilized Bronchiolitis: A Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)
Editorial: Should We Prioritize Deimplementation of Continuous Pulse Oximetry in Bronchiolitis Care?
M-A: Glue vs. mechanical mesh fixation in laparoscopic inguinal hernia repair
2 Mar, 2021 | 01:29h | UTC


