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Systematic review: Aldosterone antagonists for people with chronic kidney disease requiring dialysis

3 Mar, 2021 | 08:27h | UTC

Aldosterone antagonists for people with chronic kidney disease requiring dialysis – Cochrane Library

 


RCT: Effect of Blinatumomab vs. Chemotherapy in children with high-risk first-relapse B-Cell Acute Lymphoblastic Leukemia

3 Mar, 2021 | 08:19h | UTC

Effect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA (free for a limited period)

Related study: Effect of Postreinduction Therapy Consolidation With Blinatumomab vs Chemotherapy on Disease-Free Survival in Children, Adolescents, and Young Adults With First Relapse of B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Blinatumomab for Treatment of Children With High-risk Relapsed B-Cell Acute Lymphoblastic Leukemia – JAMA (free for a limited period)

 


Chronic suppurative otitis media: Cochrane evidence on treatment options

3 Mar, 2021 | 08:26h | UTC

Chronic suppurative otitis media (infection and inflammation of the middle ear): Cochrane evidence on treatment options – Evidently Cochrane

 


RCT: Omega-3 supplements do not reduce cardiovascular events in elderly patients after myocardial infarction

3 Mar, 2021 | 08:13h | UTC

Effects of n-3 Fatty Acid Supplements in Elderly Patients After Myocardial Infarction: A Randomized, Controlled Trial – Circulation (link to abstract – $ for full-text)

Commentary: Omega-3 fatty acids did not reduce risk of cardiac events in elderly heart attack survivors – News Medical

 

Commentary on Twitter

 


M-A: Role of Cilostazol in prevention of vasospasm following aneurysmal subarachnoid hemorrhage

3 Mar, 2021 | 08:16h | UTC

Role of Cilostazol in prevention of vasospasm following aneurysmal subarachnoid hemorrhage – A systematic review, meta-analysis and trial sequential analysis – World Neurosurgery (link to abstract – $ for full-text)

 


The predicative clinical features associated with chronic cough that has a single underlying cause

3 Mar, 2021 | 08:14h | UTC

The Predicative Clinical Features Associated with Chronic Cough That Has a Single Underlying Cause – The Journal of Allergy and Clinical Immunology: In Practice

News release: Clinical features for indicating causes of chronic cough – American Academy of Allergy, Asthma & Immunology

 


Five-year outcomes from randomized, phase III trials: Nivolumab vs. Docetaxel in previously treated non–small-cell lung cancer

3 Mar, 2021 | 08:10h | UTC

Five-Year Outcomes From the Randomized, Phase III Trials CheckMate 017 and 057: Nivolumab Versus Docetaxel in Previously Treated Non–Small-Cell Lung Cancer – Journal of Clinical Oncology

 

Commentary on Twitter

 


Another study shows higher antibody titer responses to a single dose of mRNA vaccine among patients with previous COVID-19 infection

2 Mar, 2021 | 02:13h | UTC

Binding and Neutralization Antibody Titers After a Single Vaccine Dose in Health Care Workers Previously Infected With SARS-CoV-2 – JAMA

Related: Studies: Single dose of vaccine acts as ‘booster’ in those with prior COVID-19 infection (studies and commentary)

 


RCT: Extended vs. limited pelvic lymph node dissection during radical prostatectomy for intermediate- and high-risk prostate cancer

3 Mar, 2021 | 08:05h | UTC

Extended Versus Limited Pelvic Lymph Node Dissection During Radical Prostatectomy for Intermediate- and High-risk Prostate Cancer: Early Oncological Outcomes from a Randomized Phase 3 Trial – European Urology (link to abstract – $ for full-text)

Commentary: Extended pelvic lymph node dissection during RP does not appear beneficial – Urology Times

 

Commentary on Twitter

 


M-A: Local salvage therapies after radiotherapy for prostate cancer

3 Mar, 2021 | 08:06h | UTC

A Systematic Review and Meta-analysis of Local Salvage Therapies After Radiotherapy for Prostate Cancer (MASTER) – European Urology (link to abstract – $ for full-text)

 

Commentary on Twitter (thread – click for more)

 


WHO: Roadmap to improve and ensure good indoor ventilation in the context of COVID-19

2 Mar, 2021 | 02:15h | UTC

Roadmap to improve and ensure good indoor ventilation in the context of COVID-19 – World Health Organization

 

Commentary on Twitter

 


Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children

2 Mar, 2021 | 02:11h | UTC

Acute covid-19 and multisystem inflammatory syndrome in children – The BMJ

 

Commentary on Twitter

 


Studies: Secondary infections in patients with severe COVID-19

2 Mar, 2021 | 02:05h | UTC

Secondary Infections in Patients with Severe COVID-19 – NEJM Journal Watch

Study 1: Nosocomial infections associated to COVID-19 in the intensive care unit: clinical characteristics and outcome – Intensive Care Medicine

Study 2: COVID-19 increased the risk of ICU-acquired bloodstream infections: a case–cohort study from the multicentric OUTCOMEREA network – Intensive Care Medicine

 


Scaling up COVID-19 rapid antigen tests: promises and challenges

2 Mar, 2021 | 02:09h | UTC

Scaling up COVID-19 rapid antigen tests: promises and challenges – The Lancet Infectious Diseases

 


Review: Cardiovascular biomarkers in patients with COVID-19

2 Mar, 2021 | 02:07h | UTC

Cardiovascular biomarkers in patients with COVID-19 – European Heart Journal. Acute Cardiovascular Care

 

Commentary on Twitter

 


Serious bradycardia and Remdesivir for COVID-19: a new safety concern

2 Mar, 2021 | 02:06h | UTC

Serious bradycardia and remdesivir for coronavirus 2019 (COVID-19): a new safety concerns – Clinical Microbiology and Infection

 

Commentary on Twitter

 


Systematic Review: Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19

2 Mar, 2021 | 01:54h | UTC

Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19 – Cochrane Library

Summary: Can symptoms and medical examination accurately diagnose COVID-19? – Cochrane Library

 

 


Consensus Document: Venous thromboembolism prophylaxis in the trauma intensive care unit

2 Mar, 2021 | 01:52h | UTC

Venous thromboembolism prophylaxis in the trauma intensive care unit: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document – Trauma Surgery & Acute Care Open

 


Vaccinating the oldest against COVID-19 saves both the most lives and most years of life

2 Mar, 2021 | 02:04h | UTC

Vaccinating the oldest against COVID-19 saves both the most lives and most years of life – Proceedings of the National Academy of Sciences

Commentary: Vaccinating Oldest First for COVID Saves the Most Lives: Study – HealthDay

 

Commentary on Twitter

 


Guideline: Treatment of methicillin-resistant Staphylococcus aureus (MRSA)

2 Mar, 2021 | 01:50h | UTC

Treatment of methicillin-resistant Staphylococcus aureus (MRSA): updated guidelines from the UK – JAC-Antimicrobial Resistance

 

Commentary on Twitter

 


Who gets a COVID-19 vaccine and who pays? The need for economic analysis

2 Mar, 2021 | 02:02h | UTC

Who Gets a COVID-19 Vaccine and Who Pays? The Need for Economic Analysis – Center for Global Development

 

Commentary on Twitter

 


Fruit and Vegetable Intake and Mortality: Results From 2 Prospective Cohort Studies of US Men and Women and a Meta-Analysis of 26 Cohort Studies

2 Mar, 2021 | 01:44h | UTC

Fruit and Vegetable Intake and Mortality: Results From 2 Prospective Cohort Studies of US Men and Women and a Meta-Analysis of 26 Cohort Studies – Circulation

News release: The right ‘5-a-day’ mix is 2 fruit and 3 vegetable servings for longer life – American Heart Association

 


Systematic review: Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge

2 Mar, 2021 | 01:46h | UTC

Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge: a systematic review – JAC-Antimicrobial Resistance

 

Commentary on Twitter

 


RCT: Similar outcomes with intermittent vs. continuous pulse oximetry in hospitalized infants with stabilized bronchiolitis

2 Mar, 2021 | 01:42h | UTC

Intermittent vs Continuous Pulse Oximetry in Hospitalized Infants With Stabilized Bronchiolitis: A Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)

Editorial: Should We Prioritize Deimplementation of Continuous Pulse Oximetry in Bronchiolitis Care?

 


M-A: Glue vs. mechanical mesh fixation in laparoscopic inguinal hernia repair

2 Mar, 2021 | 01:29h | UTC

Glue versus mechanical mesh fixation in laparoscopic inguinal hernia repair: meta-analysis and trial sequential analysis of randomized clinical trials – British Journal of Surgery

 


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