All Posts
Opinion | Platform Trials — Beware the Noncomparable Control Group
22 Apr, 2021 | 08:44h | UTCPlatform Trials — Beware the Noncomparable Control Group – New England Journal of Medicine
A year in the COVID-19 vaccine scheme COVAX
22 Apr, 2021 | 08:43h | UTCA year in the COVID-19 vaccine scheme COVAX – Reuters
Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease
22 Apr, 2021 | 08:40h | UTC
Commentaries on Twitter
Early data from @RCHMelbourne show that, at 3-6 month follow-up, all 151 children with mild and asymptomatic #COVID19 had returned to their baseline health status and post-acute COVID-19 symptoms had resolved.
Letter from @Shidan_Tosif & colleagues: https://t.co/XXa0EPIgPY
— The Lancet Child & Adolescent Health (@LancetChildAdol) April 20, 2021
Given such little available data, this study from Australia on post-acute COVID-19 symptoms in children is very important
Findings are extremely reassuring
Post-acute symptoms were rare, and mild (cough 4%, fatigue 2%, cough and fatigue 1%)
Great news!https://t.co/TEJyES3Crx
— Alasdair Munro (@apsmunro) April 21, 2021
Great to see research looking at whether long Covid is a problem in children.
From this Melbourne cohort, enduring cough and fatigue are uncommon.
It hasn’t been clear to me whether borders will reopen before children are vaccinated so this is VIP https://t.co/iLXqwXJmOt
— Jin Russell (@DrJinRussell) April 21, 2021
Truly encouraging data on post-acute #COVID19 in children. Single-center in Australia. n=151.
8% post-acute symptoms – all symptomatic COVID-19.
Mild symptoms: cough 4%, fatigue 2%, both 1%. Duration: cough 3-8w; post-viral fatigue 6-8w. All solved in follow-up time 3-6 months. https://t.co/vKrEFZlw3C— Pablo Guisado Vasco (@PabloGVasco) April 21, 2021
Perspective | Do Kids Really Need to Be Vaccinated for Covid? Yes. No. Maybe.
22 Apr, 2021 | 08:38h | UTCDo Kids Really Need to Be Vaccinated for Covid? Yes. No. Maybe. – Undark
Commentary on Twitter
Great article by @Sara_Talpos
key qs:
1 Does a kid need to be vaccinated for their sake?
2 Does a kid need to be vaccinated to protect adults who decline?
3. Does a kid need to be vaccinated to protect adults who were vax'd?— Vinay Prasad MD MPH (@VPrasadMDMPH) April 20, 2021
India’s massive COVID surge puzzles scientists
22 Apr, 2021 | 08:36h | UTCIndia’s massive COVID surge puzzles scientists – Nature
See also: ‘The system has collapsed’: India’s descent into Covid hell – The Guardian AND India’s COVID-19 surge intensifies – CIDRAP
ISTH Interim Guidance for the Diagnosis and Treatment on Vaccine Induced Immune Thrombotic Thrombocytopenia
21 Apr, 2021 | 07:11h | UTCSee also: Diagnostic Flow Chart
Commentary on Twitter
The ISTH has released interim guidance on vaccine-induced immune thrombotic thrombocytopenia (#VITT) to inform the management of suspected thrombosis in subjects who have recently received the AstraZeneca or Johnson & Johnson vaccine. https://t.co/qqtQtpywaf pic.twitter.com/wNmjNNDs4z
— ISTH (@isth) April 20, 2021
Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions
22 Apr, 2021 | 08:19h | UTCSee also: Final Report AND Evidence Summary
How COVID hurt the fight against other dangerous diseases
22 Apr, 2021 | 08:35h | UTCHow COVID hurt the fight against other dangerous diseases – Nature
Related: World TB Day | Report: COVID-19 Eliminates Twelve Years of Progress Against Tuberculosis AND WHO: Benefits of continuing to provide life-saving HIV services outweigh the risk of COVID-19 transmission by 100 to 1
NICE Guideline | Neonatal infection: antibiotics for prevention and treatment
21 Apr, 2021 | 06:46h | UTC
Review: Long-Term Infectious Complications of Kidney Transplantation
22 Apr, 2021 | 08:16h | UTC
RCT: Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer
22 Apr, 2021 | 08:15h | UTCSacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
NICE Guideline | Postnatal care
21 Apr, 2021 | 06:43h | UTCPostnatal care – National Institute for Health and Care Excellence
Cohort study: Increased bleeding risk with no therapeutic benefit with the addition of aspirin to direct oral anticoagulant therapy when there is not a clear indication
21 Apr, 2021 | 06:34h | UTCAdverse Events Associated With the Addition of Aspirin to Direct Oral Anticoagulant Therapy Without a Clear Indication – JAMA Internal Medicine (free for a limited period)
Commentaries: DOAC + Aspirin Common Without Clear Indication, Tied to More Bleeding – NEJM Journal Watch AND Many AFib patients wrongly prescribed aspirin therapy, study finds – UPI
Commentary on Twitter
Obs study in @JAMAInternalMed finds aspirin is often prescribed along w/ direct acting oral anticoagulant without clear reason and the combo *associates* w higher rates of bleeding https://t.co/nKsWtLnjr9
Good one @GBarnesMD
ASA is the number 1 drug I #deprescribe
— John Mandrola, MD (@drjohnm) April 19, 2021
Systematic review: Thrombolytic therapy for acute massive or submassive pulmonary embolism
21 Apr, 2021 | 06:20h | UTCThrombolytic therapy for pulmonary embolism – Cochrane Library
Summary: Drugs to dissolve pulmonary embolism (blood clot in the lungs) – Cochrane Library
Study: Postprandial glycemic dips predict appetite and energy intake in healthy individuals
21 Apr, 2021 | 06:36h | UTCCommentaries: New research reveals why some of us are hungry all the time – King’s College London AND The easy test that predicts the size of your next few meals – Nature AND Feeling Hungry All The Time? Scientists Have a New Explanation For What’s Going On – Science Alert
Commentary on Twitter
https://twitter.com/nresearchnews/status/1382354527572070401
Review: Dosing Fluids in Early Septic Shock
21 Apr, 2021 | 06:19h | UTCDosing Fluids in Early Septic Shock – CHEST
USPSTF Draft Statement: Insufficient evidence to recommend screening for atrial fibrillation
21 Apr, 2021 | 06:42h | UTCCommentary: Little evidence supports AFib screening in stroke prevention, group says – UPI
A Knee MRI in Half the Time? It’s Possible
21 Apr, 2021 | 06:24h | UTCA Knee MRI in Half the Time? It’s Possible – Diagnostic Imaging
Original study: Five-Minute Five-Sequence Knee MRI Using Combined Simultaneous Multislice and Parallel Imaging Acceleration: Comparison with 10-Minute Parallel Imaging Knee MRI – Radiology (link to abstract – $ for full-text)
Commentary on Twitter
RADIOLOGY New: Dr. Jan Fritz @NYUImaging, 252 adults assessing a 5 min #MRI protocol, excellent results. https://t.co/hcMY34dJSI @radiology_rsna pic.twitter.com/OPdd7NOUWb
— @RadiologyEditor (@RadiologyEditor) April 13, 2021
COVID-19 Vaccine Janssen: EMA finds possible link to very rare cases of unusual blood clots with low blood platelets
21 Apr, 2021 | 07:07h | UTCCommentary: Johnson & Johnson vaccine: EU regulator says blood clot very rare side effect – BBC
Commentary on Twitter
https://twitter.com/hildabast/status/1384535676482297865
Vaccine-induced Immune Thrombotic Thrombocytopenia: Frequently Asked Questions
21 Apr, 2021 | 07:09h | UTC
WHO panel comes out against requiring vaccination proof for travel
21 Apr, 2021 | 07:03h | UTCWHO panel comes out against requiring vaccination proof for travel – The Hill
Related: Opinion | How to lose friends and alienate people? On the problems of vaccine passports (several texts on the subject)
What do we know about India’s Covaxin vaccine?
21 Apr, 2021 | 07:05h | UTCWhat do we know about India’s Covaxin vaccine? – The BMJ
We know a lot about Covid-19. Experts have many more questions
21 Apr, 2021 | 07:02h | UTCWe know a lot about Covid-19. Experts have many more questions – STAT
Bioethics | COVID: Is it OK to manipulate people into getting vaccinated?
21 Apr, 2021 | 07:00h | UTCCOVID: Is it OK to manipulate people into getting vaccinated? – The Conversation
M-A: Corticosteroids in COVID-19 and non-COVID-19 ARDS
20 Apr, 2021 | 06:11h | UTC