All Posts
Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons
22 Apr, 2021 | 08:49h | UTCAudio Interview: Covid-19 Vaccines and Pregnancy — A Conversation with CDC Director Rochelle Walensky – New England Journal of Medicine
Commentaries: No evidence that Pfizer or Moderna vaccines are unsafe during pregnancy, a preliminary study says. – The New York Times AND Preliminary data show no safety concerns for pregnant women receiving COVID-19 vaccines – AAP News AND Messenger RNA COVID vaccines likely safe for pregnant women: Study – ABC News
Covid-19: What do we know about airborne transmission of SARS-CoV-2?
23 Apr, 2021 | 08:33h | UTCCovid-19: What do we know about airborne transmission of SARS-CoV-2? – The BMJ
Related: Ten scientific reasons in support of airborne transmission of SARS-CoV-2 AND Editorial: Covid-19 has redefined airborne transmission
COVID vaccines and kids: five questions as trials begin
23 Apr, 2021 | 08:37h | UTCCOVID vaccines and kids: five questions as trials begin – Nature
Related perspective: Do Kids Really Need to Be Vaccinated for Covid? Yes. No. Maybe. – Undark
Systematic review shows there is insufficient evidence on the best approaches to stop long‐term antidepressant use – “Future studies should distinguish carefully between relapse and withdrawal symptoms”
23 Apr, 2021 | 08:19h | UTCAuthor interview: Stopping long-term antidepressants in people with depression or anxiety – Cochrane Library
Commentary: ‘Urgent’ need for more evidence on safely stopping antidepressants, say experts – Metro
“Future studies should distinguish carefully between relapse and withdrawal symptoms and follow emerging guidance to use taper schemes of many weeks or months (or longer for long-term users) down to very low doses before stopping. Such studies would give us a clearer idea of the ability of antidepressants to prevent relapse.”
Commentary on Twitter (thread – click for more)
Outline of the Cochrane study a bit for those scared of its length. Metro article: https://t.co/3c32xjGJsr Lead author: the dauntless Ellen van Leuween. Co-author @tony_kendrick https://t.co/tt4Lzyacq4 While there are hundreds of studies looking at starting antidepressants(1/n)
— Mark Horowitz @markhoro.bsky.social (@markhoro) April 22, 2021
Viewpoint | Remote Research and Clinical Trial Integrity During and After the Coronavirus Pandemic
23 Apr, 2021 | 08:34h | UTCRemote Research and Clinical Trial Integrity During and After the Coronavirus Pandemic – JAMA
AHA Scientific Statement: Obesity and Cardiovascular Disease
23 Apr, 2021 | 08:22h | UTCNews Release: More belly weight increases danger of heart disease even if BMI does not indicate obesity – American Heart Association
Perioperative hemodynamic optimization: from guidelines to implementation—an experts’ opinion paper
23 Apr, 2021 | 08:21h | UTC
RCT: Treatments for vulnerable older adult women with ovarian cancer compared
23 Apr, 2021 | 08:15h | UTCEfficacy and Safety of First-line Single-Agent Carboplatin vs Carboplatin Plus Paclitaxel for Vulnerable Older Adult Women With Ovarian Cancer: A Randomized Clinical Trial – JAMA Oncology (free for a limited period)
Editorial: Vulnerable Older Adults With Ovarian Cancer—Time to Stop Undertreating (free for a limited period)
Systematic review: Abdominal ultrasound and alpha‐foetoprotein for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease
23 Apr, 2021 | 08:17h | UTC
Systematic Review: PARP (Poly ADP‐Ribose Polymerase) inhibitors for locally advanced or metastatic breast cancer
23 Apr, 2021 | 08:16h | UTCSummary: PARP inhibitors for locally advanced or metastatic breast cancer – Cochrane Library
Survey: Despite guideline recommendations, many patients with low-risk thyroid cancer continue to be treated with suppressive doses of thyroid hormone
23 Apr, 2021 | 08:13h | UTCTSH Suppression for Papillary Thyroid Cancer: A Physician Survey Study – Thyroid (link to abstract – $ for full-text)
Commentary on Twitter
Hot off the press. We found that many patients with low-risk thyroid cancer continue to be treated with suppressive doses of thyroid hormone, emphasizing the need for more research to better guide thyroid cancer management. @AmThyroidAssn @UMRogelCancer https://t.co/iU3ObzQxBQ
— Maria Papaleontiou, MD (@MariaPapaleont1) March 30, 2021
Long-Term Cardiovascular Outcomes in Systemic Lupus Erythematosus
23 Apr, 2021 | 08:08h | UTCCardiovascular Outcomes in Systemic Lupus Erythematosus – American College of Cardiology
Original study: Long-Term Cardiovascular Outcomes in Systemic Lupus Erythematosus – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Do you really need to drink 8 glasses of water a day? An exercise scientist explains why your kidneys say ‘no’
23 Apr, 2021 | 08:11h | UTC
AGA recommends intragastric balloons as an additional weight loss option for obese patients
23 Apr, 2021 | 08:10h | UTCOriginal article: AGA Clinical Practice Guidelines on Intragastric Balloons in the Management of Obesity – Gastroenterology
General anesthesia in end‐of‐life care: extending the indications for anesthesia beyond surgery
22 Apr, 2021 | 08:26h | UTC
Commentary on Twitter
🔐"Our redefinition of the scope and reach of general anaesthesia through end‐of‐life care, radical though it is, would recognise that anaesthetists have skills that can help alleviate suffering for the dying patient."@TaklaAntony @Assoc_Anaes #FOAMed
🔗https://t.co/51Ja7lFIBU pic.twitter.com/vnpvf484my
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) April 21, 2021
New-Generation Antibiotics for Treatment of Gram-Positive Infections: A Review with Focus on Endocarditis and Osteomyelitis
23 Apr, 2021 | 08:06h | UTC
Financial Toxicity in Advanced and Metastatic Cancer: Overburdened and Underprepared
22 Apr, 2021 | 08:24h | UTCRelated: Opinion – The high price of anticancer drugs: origins, implications, barriers, solutions AND Tackling the High Cost of Cancer Care AND Study: Clinician Engagement Regarding Financial Toxicity After Diagnosis of Cancer AND
An Update on Eight “New” Antibiotics against Multidrug-Resistant Gram-Negative Bacteria
23 Apr, 2021 | 08:05h | UTC
Opportunities and Challenges for the Next Phase of Enhanced Recovery After Surgery
22 Apr, 2021 | 08:28h | UTCOpportunities and Challenges for the Next Phase of Enhanced Recovery After Surgery: A Review – JAMA Surgery (free for a limited period)
See also: Enhanced Recovery After Surgery (ERAS) Society Guidelines
Ahead of World Malaria Day, WHO launches effort to stamp out malaria in 25 more countries by 2025
22 Apr, 2021 | 08:23h | UTCReport: Zeroing in on malaria elimination: Final report of the E-2020 initiative – World Health Organization
Review: Oral Antiplatelet Therapy After Acute Coronary Syndrome
22 Apr, 2021 | 08:22h | UTCOral Antiplatelet Therapy After Acute Coronary Syndrome: A Review – JAMA (free for a limited period)
Audio Clinical Review: Dual Antiplatelet Therapy After Acute Coronary Syndrome – JAMA
Guideline: Diagnosis and Evaluation of Hypersensitivity Pneumonitis
22 Apr, 2021 | 08:21h | UTCSee also: Executive Summary
Systematic review: Venoarterial Extracorporeal Membrane Oxygenation in Massive Pulmonary Embolism-Related Cardiac Arrest
22 Apr, 2021 | 08:18h | UTCSummary: VA ECMO for Massive PE + Cardiac Arrest – Journal Feed
M-A: Aspirin alone better than dual antiplatelet therapy after transcatheter aortic valve implantation
22 Apr, 2021 | 08:20h | UTC
Vaccine Breakthrough Infections with SARS-CoV-2 Variants
22 Apr, 2021 | 08:47h | UTCVaccine Breakthrough Infections with SARS-CoV-2 Variants – New England Journal of Medicine
Commentary on Twitter
Mild #COVID19 symptoms developed in two fully vaccinated persons. Serum tests showed high titers of antibodies capable of neutralizing the wild-type strain of #SARSCoV2 first identified in Wuhan, China, but sequencing of the virus isolates revealed novel variants.
— NEJM (@NEJM) April 21, 2021