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Characteristics associated with Multisystem Inflammatory Syndrome among adults with SARS-CoV-2 infection
20 May, 2021 | 08:52h | UTCCommentary: COVID-related inflammatory syndrome looks different in adults – CIDRAP
M-A: Psychologic treatment of depression compared with pharmacotherapy and combined treatment in primary care – Psychotherapy has comparable effects to those of pharmacotherapy, and combined treatment might be better than either psychotherapy or pharmacotherapy alone.
20 May, 2021 | 08:34h | UTC
Commentary on Twitter
https://twitter.com/pimcuijpers/status/1391999860505825286
Systematic review: Prognostic factors for pain chronicity in low back pain – “Higher pain intensity, higher body weight, carrying heavy loads at work, difficult working positions, and depression were the most frequently observed risk factors for chronic low back pain”
20 May, 2021 | 08:32h | UTCPrognostic factors for pain chronicity in low back pain: a systematic review – Pain Reports
Global survey finds 44% of cardiologists report a hostile work environment. Higher rates were found among women (68%) vs. men (37%).
20 May, 2021 | 08:35h | UTCGlobal Prevalence and Impact of Hostility, Discrimination, and Harassment in the Cardiology Workplace – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Editorial: Hostile Work Environment: A Case of the Emperor’s New Clothes
Commentary: Hostility Is Common in Cardiology: Can a New ACC/AHA Statement Help? – TCTMD
Commentary on Twitter
Global Prevalence and Impact of Hostility, Discrimination, and Harassment in the Cardiology Workplace – PubMed. A global problem for cardiology….What would you do… if it was career damaging to say nothing…and career damaging to speak up? https://t.co/uutfsMXOsx
— A/Prof Sonya Burgess (@drsonyaburgess) May 15, 2021
A pharmacist-led penicillin allergy assessment program can delabel many “penicillin allergic” patients through allergy histories and penicillin skin testing. The program was associated with reduced use of high Clostridioides difficile infection–risk antibiotics.
20 May, 2021 | 08:30h | UTC
Commentaries on Twitter
🆕💥💥 @jamanetworkopen
Evaluation of a Pharmacist-Led Penicillin Allergy Assessment Program and Allergy Delabeling in a 3ry Care Hospital
Phase 1 : Allergy histories
Phase 2 :Allergy histories +Penicillin Skin Testing #IDTwitter https://t.co/pZfVf8TJIn pic.twitter.com/2VvnaCayqj— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) May 13, 2021
This cross-sectional study found pharmacist-driven allergy assessments may help improve antibiotic selection and clinical outcomes for patients and hospitals https://t.co/io5LcU9U9U
— JAMA Network Open (@JAMANetworkOpen) May 13, 2021
ESC Comprehensive review: Update on management of hypokalemia and goals for the lower potassium level in patients with cardiovascular disease.
20 May, 2021 | 08:26h | UTC
Commentary on Twitter
Learn about the management of hypokalemia: a comprehensive review from the ESC WG on cardiovascular pharmacotherapy https://t.co/MkwOZyvUJA@AgewallStefan @GianluSava #EHJPharmacotherapy #cardiotwitter pic.twitter.com/tUFVmycwHa
— European Society of Cardiology Journals (@ESC_Journals) May 15, 2021
24-week randomized controlled trial: Mixed tree nut snacks resulted in similar weight loss and increased satiety compared to refined carbohydrate snacks in a weight loss and maintenance program.
20 May, 2021 | 08:28h | UTCCommentary: Mixed tree nut snacks result in significant weight loss and improved satiety – News Medical
M-A: Compared to cefazolin alone, pre-incision cefazolin + adjunctive prophylaxis with macrolides or metronidazole significantly reduces the incidence of post-cesarean surgical site infection and hospital stay.
20 May, 2021 | 08:19h | UTCPre-incision Adjunctive Prophylaxis for Cesarean Sections: A Systematic Review and Meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
RCT: Reduced-intensity chemotherapy among older and frail patients with advanced gastroesophageal cancer provides an improved patient experience with no significant detriment in cancer control.
20 May, 2021 | 08:18h | UTC
Commentary on Twitter
The GO2 trial tested reduced intensity of chemo for pts w adv gastroesophageal cancer & found reducing intensity led to comparable survival but w improved patient experience, & decision-making can be enhanced using geriatric assessment https://t.co/DtZOXcozo7 #GeriOnc
— JAMA Oncology (@JAMAOnc) May 13, 2021
ERS clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years.
20 May, 2021 | 08:21h | UTC
[Preprint] RECOVERY Trial: Colchicine does not improve outcomes in patients admitted to hospital with COVID-19.
19 May, 2021 | 08:51h | UTC
Commentary on Twitter (thread – click for more)
RECOVERY pre-print: Colchicine
11340 patients hospitalised with COVID-19
Randomised to colchicine vs usual care
No significant improvement in:
– 28-day mortality
– discharge alive at 28 days
– progression to invasive mechanical ventilation or deathhttps://t.co/mEtYq2qwkL pic.twitter.com/B0MNJWDi6e— Martin Landray (@MartinLandray) May 18, 2021
Randomized trial long-term results confirm the benefits of neoadjuvant chemoradiotherapy plus surgery for esophageal cancer
20 May, 2021 | 08:16h | UTC
Commentaries on Twitter
Out at @ASCO_pubs
🔟yr Outcome of Neoadj #Chemoradiotherapy➕Surgery for #EsophagealCancer☑️Show OS benefit in locally advanced resectable esophageal or junctional #Cancer who receive preop chemorad🧪☢️ According to CROSS, persists at least🔟years‼️https://t.co/yJSibSveAh pic.twitter.com/UssnzuFiEe
— Gil Morgan, MD (@weoncologists) May 14, 2021
Survival benefit of preoperative chemoradiotherapy for patients with esophageal cancer persists – 10-year outcome of the CROSS trial https://t.co/s02sMVpYhI #esocsm #JCO @ErasmusMC @bmeyck pic.twitter.com/2JwV0iOvoB
— Journal of Clinical Oncology (@JCO_ASCO) May 5, 2021
Systematic review: Autoimmune encephalitis related to cancer treatment with immune checkpoint inhibitors – nivolumab was responsible for 61% of cases; onset occurred after a median of 3.5 treatment cycles, but very early and late presentations were common
20 May, 2021 | 08:13h | UTCAutoimmune Encephalitis Related to Cancer Treatment With Immune Checkpoint Inhibitors: Systematic Review – Neurology (link to abstract – $ for full-text)
Perspective | Covid-19: What should we do about B.1.617.2? A classic case of decision making under uncertainty.
19 May, 2021 | 08:48h | UTC
SARS-CoV-2 infects human pancreatic β-cells and elicits β-cell impairment.
19 May, 2021 | 08:49h | UTCSARS-CoV-2 infects human pancreatic β-cells and elicits β-cell impairment – Cell Metabolism
Commentary on Twitter
A new report reinforces the capability for #SARSCoV2 to infect and kill pancreatic β-islet cells, affect insulin secretion https://t.co/4tpIVNpjTf @Cell_Metabolism #diabetes @StanfordMed @stanfordimmuno @UCSF and collaborators pic.twitter.com/dG027CXS5e
— Eric Topol (@EricTopol) May 18, 2021
WHO Solidarity trial to restart with focus on drugs that act on immune responses caused by Covid-19.
19 May, 2021 | 08:47h | UTCInternational COVID-19 trial to restart with focus on immune responses – Nature
Opinion | Vaccinating children before poor morally wrong, Oxford scientist says.
19 May, 2021 | 08:44h | UTCVaccinating children before poor morally wrong, Oxford scientist says – BBC
Related: WHO: Wealthy nations urged to delay youth Covid vaccines, donate to solidarity scheme AND Editorial: Vaccinating children against SARS-CoV-2 – “Hard to justify right now for most children in most countries”. AND Opinion | American Kids Can Wait – “The U.S. should delay shots for children until global vaccine-manufacturing capacity significantly expands and the crisis in India subsides”.
Former CDC director: Direct Covid-19 vaccines to where they’re needed most.
19 May, 2021 | 08:42h | UTCFormer CDC director: Direct Covid-19 vaccines to where they’re needed most – CNN
Commentary on Twitter
Vaccine inequity is a serious problem ethically and epidemiologically. Read my latest at @CNN on why we must direct Covid vaccines to where they’re needed the most. https://t.co/2CD5xzI00h
— Dr. Tom Frieden (@DrTomFrieden) May 17, 2021
USPSTF Statement: Start colorectal cancer screening at 45 years for most patients.
19 May, 2021 | 08:40h | UTCScreening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement
Evidence Report: Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Editorials: US Preventive Services Task Force Recommendations for Colorectal Cancer Screening: Forty-Five Is the New Fifty – JAMA AND Updated USPSTF Guidelines for Colorectal Cancer Screening: The Earlier the Better – JAMA Surgery AND Colorectal Cancer Screening Starting at Age 45 Years—Ensuring Benefits Are Realized by All – JAMA Network Open AND
Modeling study: Colorectal Cancer Screening: An Updated Modeling Study for the US Preventive Services Task Force – JAMA
Author interview: USPSTF Recommendation: Screening for Colorectal Cancer
JAMA Patient Page: Screening for Colorectal Cancer
Review: Testing at scale during the COVID-19 pandemic.
19 May, 2021 | 08:45h | UTCTesting at scale during the COVID-19 pandemic – Nature Reviews Immunology
Commentary on Twitter
🆕💥 @NatureRevGenet
Testing at scale during the COVID-19 pandemic
💥Changes in modes of testing across a generalized COVID-19 infectious course💥
✨Excellent Figure ✨ https://t.co/sUZjRr1gQR pic.twitter.com/ZiOXCw7en2— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) May 10, 2021
M-A: Encephalitis as Neurological Complication of COVID‐19.
19 May, 2021 | 08:41h | UTC
ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections.
19 May, 2021 | 08:37h | UTC
Commentary on Twitter
📢New ACG Clinical Guideline on Prevention, Diagnosis & Treatment of C. difficile Infections
Focus on clinical challenges – diagnostic issues in diarrhea, distinguishing C. diff colonization from active infection + eval/mgmt of CDI in IBD
Full guideline: https://t.co/QTCzeLB9Ri pic.twitter.com/mqZUN4r4jA
— AJG – The American Journal of Gastroenterology (@AmJGastro) May 18, 2021
Fluid-induced harm in the hospital: look beyond volume and start considering sodium. From physiology towards recommendations for daily practice in hospitalized adults.
19 May, 2021 | 08:32h | UTC
Guideline: Early intervention for children aged 0 to 2 years with or at high risk of cerebral palsy.
19 May, 2021 | 08:35h | UTCEarly Intervention for Children Aged 0 to 2 Years With or at High Risk of Cerebral Palsy: International Clinical Practice Guideline Based on Systematic Reviews – JAMA Pediatrics (free for a limited period)
Editorial: Early Intervention in Cerebral Palsy and Beyond (free for a limited period)
Series: Social determinants of health in people with kidney disease.
19 May, 2021 | 08:29h | UTCIntroduction: Social Determinants of Health in People with Kidney Disease
The Pathogenesis of Race and Ethnic Disparities
Social Determinants of Kidney Health
Reducing the Burden of CKD among Latinx
The Seen and the Unseen: Race and Social Inequities Affecting Kidney Care
Personal Experiences of Patients in the Interaction of Culture and Kidney Disease
Commentary on Twitter
A series of Perspective articles were written based on talks at the 2020 Alison Norris Symposium at the New York Academy of Medicine on Social Determinants of Kidney Health. Dr. Alan M. Weinstein & Paul L. Kimmel share an overview of the program and series https://t.co/TlG0mOzZs4
— CJASN (@CJASN) May 14, 2021