All Posts
Covid-19 pandemic: approximately one million excess deaths occurred in 2020 in 29 high income countries.
21 May, 2021 | 08:52h | UTCEditorial: Measuring the impact of covid-19
Commentary: Nearly 1 million excess deaths in 29 nations during pandemic – CIDRAP
Related: COVID-19 has caused 6.9 million deaths globally, more than double what official reports show
Pessaries for pelvic organ prolapse – looking at the Cochrane evidence.
24 May, 2021 | 08:17h | UTCPessaries for pelvic organ prolapse – looking at the Cochrane evidence – Evidently Cochrane
Original Review: Pessaries (mechanical devices) for managing pelvic organ prolapse in women – Cochrane Library
Nonreplicable publications are cited more than replicable ones
24 May, 2021 | 08:15h | UTCNonreplicable publications are cited more than replicable ones – Science Advances
Commentary on Twitter
Not only does misinformation flow at considerably higher velocity across the Internet than truth, but science publications without replication are cited much more than those which are replicated
New @ScienceAdvances https://t.co/aNSKyv1alq @UriGneezy @m_serra_garcia pic.twitter.com/eWWc0NZwgi— Eric Topol (@EricTopol) May 21, 2021
Perspective | Tracking lives we’ve lost to COVID-19.
21 May, 2021 | 08:51h | UTCTracking Lives We’ve Lost to COVID-19 – Think Global Health
Related: COVID-19 has caused 6.9 million deaths globally, more than double what official reports show
How the Covid pandemic ends: Scientists look to the past to see the future.
21 May, 2021 | 08:46h | UTCHow the Covid pandemic ends: Scientists look to the past to see the future – STAT
Commentary on Twitter
https://twitter.com/HelenBranswell/status/1395007060002152450
Observational study finds a single dose of either Pfizer-BioNTech and Oxford-AstraZeneca vaccines in older adults is about 80% effective at preventing admission to hospital with covid-19.
21 May, 2021 | 08:54h | UTCEditorial: Effectiveness of England’s initial vaccine roll out – The BMJ
M-A: Prevalence and outcomes of co-infection and superinfection with SARS-CoV-2 and other pathogens – The pooled prevalence of co-infection at the time of a SARS-CoV-2 diagnosis was 19%, and that of superinfection was 24%.
21 May, 2021 | 08:48h | UTC
Report: Face masks effectively limit the probability of SARS-CoV-2 transmission.
21 May, 2021 | 08:49h | UTCFace masks effectively limit the probability of SARS-CoV-2 transmission – Science
Perspective | Contact Tracing for Covid-19 — A Digital Inoculation against Future Pandemics.
21 May, 2021 | 08:45h | UTC
RCT: In Africa, children hospitalized with severe pneumonia with oxygen saturations between 80 and 91% who did not receive oxygen had comparable mortality to children who received oxygen.
21 May, 2021 | 08:30h | UTC
Commentary on Twitter
COAST RCT O2 in African children >28 days w severe pneumonia, less is more!
SO2 80-91%? no O2 ➡️48h mortality comparable to low-flow O2/HFNC. O2-sparing strategies potentially offer cost-effective approaches to reduce requirements in low resource settings. https://t.co/8JHit94WQY pic.twitter.com/EEIybSOlmy— Intensive Care Medicine (@yourICM) May 6, 2021
Clinical review: Treatment of opioid use disorder in primary care.
21 May, 2021 | 08:31h | UTCTreatment of opioid use disorder in primary care – The BMJ (free for a limited period)
New WHO report highlights global progress on reducing HIV, viral hepatitis and sexually transmitted infections and signals need for renewed efforts to reach 2030 targets.
21 May, 2021 | 08:33h | UTCOriginal report: Global progress report on HIV, viral hepatitis and sexually transmitted infections, 2021 – World Health Organization
Commentary on Twitter (thread – click for more)
Every year HIV, viral hepatitis, and sexually transmitted infections account for 2.3M deaths, and 1.2M cancers
🆕WHO report highlights achievements, gaps, and actions towards eliminating these diseases as public health threats by 2030 👉https://t.co/8kcVqZe0Yj pic.twitter.com/U07hKRumVt
— World Health Organization (WHO) (@WHO) May 20, 2021
M-A: Comparison of treatments for cocaine use disorder among adults – Only contingency management programs were significantly associated with an increased likelihood of reductions in cocaine use among adults.
21 May, 2021 | 08:28h | UTC
M-A: Low prevalence of bacterial meningitis among well-appearing febrile infants aged 29-60 days with positive urinalysis results – “These results suggest that for these infants, the decision to use lumbar puncture should not be guided by urinalysis results alone”.
21 May, 2021 | 08:24h | UTC
Commentary on Twitter
This metanalysis found positive urinalysis alone is not an indication for LP in well looking febrile infants >28 days old. Prevalence among UA-positive infants: 0.4% vs UA-negative infants: 0.5%. https://t.co/dTzCiLHrSg
— JAMA Network Open (@JAMANetworkOpen) May 12, 2021
AARC Guideline: Management of adult patients with tracheostomy in the acute care setting.
21 May, 2021 | 08:26h | UTC
M-A: Among patients undergoing total knee arthroplasty, glucocorticoid supplementation in periarticular infiltration analgesia is effective and does not increase complications or side effects.
21 May, 2021 | 08:22h | UTC
Cohort study: Babies surviving Group B strep more likely to require special educational support.
21 May, 2021 | 08:27h | UTC
M-A: In patients with anaphylaxis, the use of multiple epinephrine doses is necessary in 7.7% of cases.
21 May, 2021 | 08:19h | UTCCommentary: How Often Does Anaphylaxis Require Redosing of Epinephrine? – Journal Feed
Systematic review: Cognitive behavioral therapy may improve outcomes for autism spectrum disorders.
21 May, 2021 | 08:21h | UTCCognitive Behavioral Therapy for Autism Spectrum Disorders: A Systematic Review – Pediatrics (link to abstract – $ for full-text)
Cohort study: 14% of adults aged 65 years or less who were infected with SARS-CoV-2 had at least one new type of clinical sequelae that required medical care after the acute phase of the illness.
20 May, 2021 | 08:59h | UTCEditorial: Unpacking post-covid symptoms – The BMJ
Commentary on Twitter (thread – click for more)
After covid infections, 14% of >266,000 people, age ≤ 65, developed at least 1 sequelae that required medical care #LongCovid Just out @bmj_latest @OptumLabs @mlipsitch Risk increased w/ pre-existing conditions but also found in healthy, age < 50 https://t.co/h8IlnRNp2v pic.twitter.com/e15uSj9BXN
— Eric Topol (@EricTopol) May 19, 2021
FDA In Brief: FDA advises against use of SARS-CoV-2 antibody test results to evaluate immunity or protection from COVID-19, including after vaccination.
20 May, 2021 | 08:55h | UTC
Commentary on Twitter (thread – click for more)
Today, we issued a safety communication notifying the public and providers that results from SARS-CoV-2 antibody tests should not be used to evaluate immunity or protection from #COVID19 at any time – especially after receiving a #COVID19 vaccination. https://t.co/KlywV04WYO pic.twitter.com/TPdIVxWzSh
— U.S. FDA (@US_FDA) May 19, 2021
Systematic review and meta-analysis of observational studies suggest low-dose aspirin may be of benefit for patients with Covid-19 – the finds require further investigation in randomized studies.
20 May, 2021 | 08:54h | UTC
One year after hospital discharge due to SARS-CoV-2 Infection, the prevalence of long-term cough, chest pain, dyspnea, and fatigue was 2.5%, 6.5%, 23.3%, and 61.2%, respectively
20 May, 2021 | 08:57h | UTCPrevalence of Post-COVID-19 Cough One Year After SARS-CoV-2 Infection: A Multicenter Study – Lung
COVID vaccines: the danger of journals being seen as substitute regulators – “the peer-review process is not adequate to evaluate a new vaccine in the way that a regulator can”.
20 May, 2021 | 08:51h | UTCCOVID vaccines: the danger of journals being seen as substitute regulators – The Conversation
Related: Covid-19: Sputnik vaccine rockets, thanks to Lancet boost
SPRINT Trial final report: targeting a systolic BP of less than 120 mm Hg in patients at increased CV risk is associated with improved CV and mortality outcomes but increases the risk of serious adverse events.
20 May, 2021 | 08:36h | UTC