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WHO and UNICEF launch new tools for the promotion of adolescent mental health.
19 May, 2021 | 08:33h | UTCNews release: WHO and UNICEF launch new tools for the promotion of adolescent mental health – World Health Organization
WHO/UNICEF Helping Adolescents Thrive programme
Helping Adolescents Thrive Toolkit
Magnificent Mei and Friends: Comic 1
The mental and brain health of children and adolescents
Commentary on Twitter (thread – click for more)
📢 NEW RELEASE : The Helping Adolescents Thrive Toolkit, developed by WHO & @UNICEF, provides guidance for people working in the health, social services, education & justice sectors on how to promote & protect adolescent mental health.
Download 👉https://t.co/gtAK7WeQC7 pic.twitter.com/x7lq6m51Ze
— World Health Organization (WHO) (@WHO) May 18, 2021
Perspective | Facebook calls links to depression inconclusive. These researchers disagree.
19 May, 2021 | 08:30h | UTCFacebook Calls Links To Depression Inconclusive. These Researchers Disagree – NPR
Related: Cohort study: Preschoolers’ extensive electronic media use linked to emotional/behavioral issues AND Analysis: Smartphones, Social Media Use and Youth Mental Health AND [Abstract Only] Study: Associations Between Time Spent Using Social Media and Mental Health Problems Among Youth AND Association of Screen Time and Depression in Adolescence AND The Adverse Effects of Social Media use on Young People’s Mental Health May be Caused by Exposure to Cyberbullying, Loss of Sleep, and Reduced Physical Activity AND Research: This Is Your Brain Off Facebook AND Cohort Study: Social Media Use and Adolescent Mental Health AND Supplement: Children, Adolescents and Screens: What We Know and What We Need To Learn
Guide to enhanced recovery for cancer patients undergoing surgery: ERAS for Patients Undergoing Cytoreductive Surgery with or Without hyperthermic intraperitoneal chemotherapy.
19 May, 2021 | 08:23h | UTCRelated Guidelines:
See also: Enhanced Recovery After Surgery (ERAS) Society Guidelines
The catastrophization effects of an MRI report on the patient and surgeon and the benefits of ‘clinical reporting’: results from an RCT and blinded trials.
19 May, 2021 | 08:25h | UTCRelated: You cannot unsee your MRI report AND Direct communication between radiologists and patients improves the quality of imaging reports – European Radiology
Commentary on Twitter
https://twitter.com/hjluks/status/1392151713700794374
Large cohort study confirms the renal toxicities of anti-inflammatories, suggesting Ibuprofen may be the safest option among them.
19 May, 2021 | 08:28h | UTCComparative Risks of Nonsteroidal Anti-Inflammatory Drugs on CKD – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)
Commentary: Study: Ibuprofen Found Safest NSAID for the Kidney – MPR
Commentary on Twitter
Comparative Risks of Nonsteroidal Anti-Inflammatory Drugs on CKD
Read this new @CJASN study and listen to the accompanying podcast:https://t.co/GL1ITzh4O4 pic.twitter.com/lZGeFqfrDZ
— American Society of Nephrology (@ASNKidney) April 29, 2021
Systematic review: Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries.
19 May, 2021 | 08:19h | UTCSummary: Paying for performance to improve the delivery of health interventions in LMICs
Systematic Review: Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome is associated with reduced risk of death or bronchopulmonary dysplasia, less intubation in the first 72 hours, and reduced incidence of major complications and in‐hospital mortality.
19 May, 2021 | 08:20h | UTC
Commentary on Twitter
https://twitter.com/CochraneUK/status/1393463418913443843
[Preprint] Practice Changing RCT: Therapeutic-dose anticoagulation with heparin (LMWH or unfractionated heparin) improves outcomes in non-critically ill patients with Covid-19 – the superiority of therapeutic-dose anticoagulation was seen in both high and low D-dimer groups.
18 May, 2021 | 08:04h | UTCTherapeutic Anticoagulation in Non-Critically Ill Patients with Covid-19 – medRxiv
Commentary on Twitter
Final results of the mpRCT now on preprint server. In non-critically ill patients with COVID-19 (n=2219), therapeutic-dose anticoagulation with heparins increases survival to hospital discharge with reduced use of organ support. https://t.co/TkhGs5qow5
— Ryan Zarychanski (@RZarychanski) May 17, 2021
#ACC21 – [Not published yet] RCT: Among hospitalized patients with Covid-19 and elevated D-Dimer, therapeutic anticoagulation with Rivaroxaban 20 mg was not associated with improved outcomes and resulted in increased major bleeding.
18 May, 2021 | 08:01h | UTCAntiCoagulaTIon cOroNavirus – ACTION – American College of Cardiology
Commentary: ACTION: Full-Dose Rivaroxaban Doesn’t Help in Hospitalized COVID-19 – TCTMD
More flexible storage conditions for BioNTech/Pfizer’s COVID-19 vaccine. – “This change extends the approved storage period of the unopened thawed vial at 2-8°C (i.e. in a normal fridge after taking out of deep-freeze conditions) from five days to one month”.
18 May, 2021 | 07:59h | UTCMore flexible storage conditions for BioNTech/Pfizer’s COVID-19 vaccine – European Medicines Agency
Commentary: EU Regulator Backs Month-Long Storage of Pfizer COVID-19 Vaccine in Fridges – U.S. News/Reuters
Commentary on Twitter
EMA has changed the recommended storage conditions for Pfizer vaccine. Instead of 5 days the thawed, unopened vials can now be stored in a normal fridge for a month. 👏 https://t.co/MVkDJRQn4b
— Kai Kupferschmidt (@kakape) May 17, 2021
COVID vaccines can block variant hitting Asia, lab study finds – “Assays using live SARS-CoV-2 offer hope that the vaccines made by Pfizer and Moderna will protect against a viral strain first seen in India”.
18 May, 2021 | 07:56h | UTCCOVID vaccines can block variant hitting Asia, lab study finds – Nature
See also: Pfizer, Moderna vaccines effective against Indian variants: study – MedicalXpress
Commentary on Twitter
Pfizer & Moderna mRNA vaccines are effective against multiple SARSCoV2 variants, including the B.1.617 & B.1.618, 2 variants underlying the surge in India. The research, while not yet peer-reviewed, was conducted at NYU School of Medicine in New York City https://t.co/3ziRhk8f4t pic.twitter.com/VzYQKWqyQF
— delthia ricks 🔬 (@DelthiaRicks) May 17, 2021
SARS-CoV-2 antibody-positivity protects against reinfection for at least seven months with 95% efficacy.
18 May, 2021 | 07:52h | UTC
M-A: Incidence and mortality of COVID‐19‐associated pulmonary aspergillosis – The incidence and mortality in the ICU were estimated to be 10.2% and 54.9%, respectively.
18 May, 2021 | 07:50h | UTC
Cohort study finds racial minorities face more severe COVID-19 outcomes.
18 May, 2021 | 07:44h | UTCRacial minorities face more severe COVID-19 outcomes – CIDRAP
Priorities for COVID-19 research response and preparedness in low-resource settings.
18 May, 2021 | 07:46h | UTCPriorities for COVID-19 research response and preparedness in low-resource settings – The Lancet
Analysis: Where are we with drug treatments for covid-19?
18 May, 2021 | 07:47h | UTCWhere are we with drug treatments for covid-19? – The BMJ
#ACC21 – The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030 – “The Lancet women and cardiovascular disease Commission outlines 10 ambitious recommendations to improve health outcomes for millions of women”.
18 May, 2021 | 07:32h | UTCHomepage: The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030 – The Lancet (free registration required)
Infographic: Women and cardiovascular disease
Video: The Lancet women and cardiovascular disease Commission
News release: Experts call for urgent action to reduce global burden of cardiovascular disease in women by 2030 – The Lancet
Commentary on Twitter (thread – click for more)
Cardiovascular disease is responsible for 35% of deaths in women yearly—yet remains:
❣️Understudied
❣️Under-recognised
❣️Underdiagnosed
❣️UndertreatedNEW @TheLancet Commission outlines 10 recommendations to improve health outcomes for millions of women: https://t.co/DDB97FFunC pic.twitter.com/WjV3aqqLV9
— The Lancet (@TheLancet) May 17, 2021
#ACC21 – RCT: Clopidogrel better than aspirin for chronic maintenance monotherapy after percutaneous coronary intervention.
18 May, 2021 | 07:34h | UTCAspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention (HOST-EXAM): an investigator-initiated, prospective, randomised, open-label, multicentre trial – The Lancet (free registration required)
Commentaries: Harmonizing Optimal Strategy for Treatment of coronary artery diseases-EXtended Antiplatelet Monotherapy – HOST-EXAM – American College of Cardiology AND Clopidogrel, Not Aspirin, for Post-DAPT Monotherapy After PCI: HOST-EXAM – TCTMD
Commentary on Twitter
The sensational news of the day comes from South Korea. In a timely comparison of single antiplatelet monotherapies, clopidogrel beats aspirin during the chronic maintenance period after PCI, with curves diverging at 9 months. #ACC21https://t.co/Pp49LxcNWf pic.twitter.com/J9Un4QHzgL
— Davide Capodanno (@DFCapodanno) May 16, 2021
WHO study estimates long working hours causing 745.000 deaths a year from heart disease and stroke.
18 May, 2021 | 07:29h | UTCNews Release: Long working hours increasing deaths from heart disease and stroke: WHO, ILO – World Health Organization
Commentary: Long working hours killing 745,000 people a year, study finds – BBC
Commentary on Twitter (thread – click for more)
🆕 WHO & @ilo analysis shows that working 55 hours or more per week impacts #WorkersHealth & increases risk of cardiovascular diseases.
Long working hours led to 745 000 deaths from #stroke & ischemic heart disease in 2016, a 2⃣9⃣% rise ↗️ since 2000.
👉 https://t.co/T3nuPX3nH7 pic.twitter.com/UW5XxbjWqo
— World Health Organization (WHO) (@WHO) May 17, 2021
Opinion | E-Cigarettes and the U.S. Menthol Ban: A Missed Opportunity to Protect Youth.
18 May, 2021 | 07:28h | UTCE-Cigarettes and the U.S. Menthol Ban: A Missed Opportunity to Protect Youth – Think Global Health
Commentary on Twitter (thread – click for more)
📢📢📢 @US_FDA should ban flavors in all nicotine-containing products, not just menthol cigarettes. More than 8 out of 10 current youth e-cigarette users in the U.S. vape non-tobacco flavors.
IHME researchers for @ThinkGlobalHlth 🧵⤵️ https://t.co/d56mDCvTY3
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) May 17, 2021
M-A: Screening test (Hospital Anxiety and Depression Scale – HADS-D) can identify hospitalized patients with depression.
18 May, 2021 | 07:23h | UTCKnowledge translation tool: Using the HADS-D to Screen for Depression
Commentary on Twitter (thread – click for more)
Our @DepressdP IPDMA on HADS-D accuracy, led by Dr. Yin Wu, was published today in @bmj_latest! We pooled data from 101 studies and found that a cutoff of >=7 maximized combined sensitivity and specificity. Read more here: https://t.co/iMmsjoeW7f
— Brooke Levis (@blevis_epi) May 10, 2021
Systematic review: Treatment of gastro-esophageal reflux disease to help manage asthma in adults and children may result in reduced use of rescue medications, but the benefits on the number of exacerbations and hospital utilization remain uncertain.
18 May, 2021 | 07:27h | UTC
Expert consensus on peri-operative myocardial injury screening in noncardiac surgery.
18 May, 2021 | 07:12h | UTCInvited Commentary: Expert consensus on peri-operative myocardial injury screening in noncardiac surgery
RCT: Among patients with esophageal cancer, intrathoracic anastomosis after totally or hybrid minimally invasive esophagectomy resulted in lower anastomotic leakage rates and better outcomes when compared with cervical anastomosis.
18 May, 2021 | 07:21h | UTCIntrathoracic vs Cervical Anastomosis After Totally or Hybrid Minimally Invasive Esophagectomy for Esophageal Cancer: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Invited commentary: Does the Location Matter for the Anastomosis for Minimally Invasive Esophagectomy? (free for a limited period)
Commentary on Twitter
Intrathoracic anastomosis after MIE is associated with a lower anastomotic leakage rate and better outcome for patients with mid to distal esophageal or gastro-esophageal junction cancer: results of the ICAN trial https://t.co/CXv2CeCnuX pic.twitter.com/QCYg4UJeyF
— JAMA Surgery (@JAMASurgery) May 12, 2021
NICE Guideline Update | Headaches in over 12s: diagnosis and management.
18 May, 2021 | 07:14h | UTCHeadaches in over 12s: diagnosis and management – National Institute for Health and Care Excellence