Open access
Open access
Powered by Google Translator Translator

All Posts

M-A: Colchicine in patients with coronary artery disease – “colchicine reduces the risk of myocardial infarction and stroke, but has a higher rate of gastrointestinal upset with no influence on all‐cause mortality”.

8 Aug, 2021 | 23:40h | UTC

Colchicine in Patients With Coronary Artery Disease: A Systematic Review and Meta‐Analysis of Randomized Trials – Journal of the American Heart Association

Related:

Review: Colchicine and the heart.

M-A: Colchicine administration for percutaneous coronary intervention

M-A: Efficacy and safety of low-dose colchicine in patients with coronary disease

Meta-analysis: Colchicine reduces new cardiovascular events in patients with coronary artery disease

Expert analysis: Efficacy and safety of colchicine in patients with chronic stable coronary disease

#ESCCongress – [Abstract Only] Randomized trial: Colchicine in patients with chronic coronary disease

#ESCCongress – Randomized trial: Colchicine not beneficial for patients with acute coronary syndrome

#ESCCongress – Time-to-treatment initiation of colchicine and cardiovascular outcomes after myocardial infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT)

#AHA19 – [Abstract Only] Practice Changing? – Randomized Trial: Low-Dose Colchicine Improves Outcomes after Myocardial Infarction

Research: Colchicine Therapy and Plaque Stabilization in Patients With Acute Coronary Syndrome

 

Endometrial scratching: what’s the latest evidence? – “we are uncertain whether endometrial injury has an effect on the probability of getting pregnant and having a baby”.

8 Aug, 2021 | 23:33h | UTC

Endometrial scratching: what’s the latest evidence? – Cochrane Library

Original Review: Endometrial injury for pregnancy following sexual intercourse or intrauterine insemination – Cochrane Library

 

Commentary on Twitter

 

RCT: Efficacy of concurrent chemoradiotherapy with S-1 vs. radiotherapy alone for older patients with esophageal cancer.

8 Aug, 2021 | 23:35h | UTC

Efficacy of Concurrent Chemoradiotherapy With S-1 vs Radiotherapy Alone for Older Patients With Esophageal Cancer: A Multicenter Randomized Phase 3 Clinical Trial – JAMA Oncology (free for a limited period)

Editorial: Primary Chemoradiotherapy for Older Patients With Esophageal Cancer (free for a limited period)

Commentary: Concurrent CRT Effective for Esophageal Cancer in Older Patients — Overall survival at 2 years significantly better versus radiotherapy alone – MedPage Today (free registration required)

 

Commentary on Twitter

 

Sudden Death in Adults: A practical flow chart for pathologist guidance.

8 Aug, 2021 | 23:27h | UTC

Sudden Death in Adults: A Practical Flow Chart for Pathologist Guidance – Healthcare

 

Perspective: Does Treating Sleep Apnea With CPAP Improve Cardiovascular Outcomes or Lower Risk of Atrial Fibrillation? – “Despite numerous flawed observational studies suggesting an association between sleep apnea and cardiovascular outcomes including atrial fibrillation the gold standard, high-quality RCT data do not clearly show that treatment of sleep apnea with CPAP improves cardiovascular outcomes”.

8 Aug, 2021 | 23:31h | UTC

Does Treating Sleep Apnea With CPAP Improve Cardiovascular Outcomes or Lower Risk of Atrial Fibrillation? – The Skeptical Cardiologist

Related:

AHA Scientific Statement: Obstructive Sleep Apnea and Cardiovascular Disease.

Non-sleepy Obstructive Sleep Apnea: To Treat or Not to Treat?

Pro/Con Debate: Should Asymptomatic Patients with Moderate-to-severe OSA be Treated?

Obstructive Sleep Apnea in Cardiovascular Disease: A Review of the Literature and Proposed Multidisciplinary Clinical Management Strategy

Positive airway pressure doesn’t reduce cardiovascular events and death in adults with sleep apnea

 

[Preprint] RCT: non-invasive respiratory strategies in acute respiratory failure in patients with COVID-19 – CPAP reduced the composite outcome of intubation or death within 30 days; high-flow nasal oxygenation was not associated with better outcomes.

6 Aug, 2021 | 10:18h | UTC

An adaptive randomized controlled trial of non-invasive respiratory strategies in acute respiratory failure patients with COVID-19 – medRxiv

Commentary: Covid: Pressured oxygen reduces ventilator need – BBC

 

Commentary on Twitter (thread – click for more)

 

Antibody-mediated autoimmune encephalitis: A practical approach.

8 Aug, 2021 | 23:29h | UTC

Antibody-mediated autoimmune encephalitis: A practical approach – Cleveland Clinic Journal of Medicine

 

Review: Transmission of infections during cardiopulmonary resuscitation.

8 Aug, 2021 | 23:16h | UTC

Transmission of Infections during Cardiopulmonary Resuscitation – Clinical Microbiology Reviews

 

Perspective | Expertise from outside the Academy: tapering off antidepressants.

8 Aug, 2021 | 23:27h | UTC

Expertise from outside the Academy: tapering off antidepressants – The Mental Elf

Related:

A method for tapering antipsychotic treatment that may minimize the risk of relapse

Systematic Review: Managing Antidepressant Discontinuation

Randomized controlled trial: preventive cognitive therapy for prevention of depressive recurrence

M-A: Continuation of antidepressants vs. sequential psychological interventions to prevent relapse in depression.

 

Systematic Review: “Remdesivir probably has little or no effect on all‐cause mortality at up to 28 days in hospitalized adults with SARS‐CoV‐2 infection. We are uncertain about the effects of remdesivir on clinical improvement and worsening”.

6 Aug, 2021 | 10:15h | UTC

Remdesivir for the treatment of COVID‐19 – Cochrane Library

Summary: Remdesivir for the treatment of COVID-19 – Cochrane Library

 

Commentary on Twitter (thread – click for more)

 

Flawed ivermectin preprint highlights challenges of COVID drug studies.

6 Aug, 2021 | 10:07h | UTC

Flawed ivermectin preprint highlights challenges of COVID drug studies – Nature

Related:

Systematic review: no evidence to support the use of Ivermectin for treating or preventing COVID-19.

Why was a major study on ivermectin for covid-19 just retracted?

 

Dexamethasone and tocilizumab treatment considerably reduces the value of C-reactive protein and procalcitonin to detect secondary bacterial infections in COVID-19 patients.

6 Aug, 2021 | 10:13h | UTC

Dexamethasone and tocilizumab treatment considerably reduces the value of C-reactive protein and procalcitonin to detect secondary bacterial infections in COVID-19 patients – Critical Care

 

Clinical Picture: Mucormycosis after COVID-19 in a patient with diabetes.

6 Aug, 2021 | 10:09h | UTC

Mucormycosis after COVID-19 in a patient with diabetes – The Lancet

Related:

COVID-19 and mucormycosis superinfection: the perfect storm.

ECMM/ISHAM recommendations for clinical management of COVID -19 associated mucormycosis in low- and middle-income countries.

The “Black Fungus” in India: The Emerging Syndemic of COVID-19–Associated Mucormycosis – careful use of antibiotics and corticosteroids and closely monitoring blood glucose levels are some of the strategies suggested by the authors.

Multicenter Epidemiologic Study of Coronavirus Disease–Associated Mucormycosis, India – Uncontrolled diabetes mellitus was the most common underlying disease; improper glucocorticoid use was independently associated with the disease.

Opinion | “Doctors have been blamed for the rise in black fungus in India, but the COVID treatment guidelines could be contributing” – improper use of antibiotics and higher than usual doses of corticosteroids may be contributing to the emergence of mucormycosis and other fungal co-infections.

What is mucormycosis, the fungal infection affecting COVID patients in India?

[Preprint] The Emergence of COVID-19 Associated Mucormycosis: Analysis of Cases From 18 Countries.

Mucormycosis: The ‘black fungus’ maiming Covid patients in India

Global Guideline for the Diagnosis and Management of Mucormycosis

 

M-A: Chest radiograph findings in COVID-19.

6 Aug, 2021 | 10:03h | UTC

Systematic review and meta-analysis of chest radiograph (CXR) findings in COVID-19 – Clinical Imaging

 

Review of COVID-19: Abdominal manifestations in adults and multisystem inflammatory syndrome in children.

6 Aug, 2021 | 10:05h | UTC

Review of COVID-19, part 1: Abdominal manifestations in adults and multisystem inflammatory syndrome in children – Clinical Imaging

 

PIDS-IDSA Guideline on diagnosis and management of acute hematogenous osteomyelitis in pediatrics.

6 Aug, 2021 | 09:58h | UTC

Clinical Practice Guideline by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America: 2021 Guideline on Diagnosis and Management of Acute Hematogenous Osteomyelitis in Pediatrics – Journal of the Pediatric Infectious Diseases Society

News release: New PIDS-IDSA guideline on bone infections in children addresses key diagnostic and treatment questions – Pediatric Infectious Diseases Society

 

Fibrotic interstitial lung abnormalities at 1-year follow-up CT after severe COVID-19.

6 Aug, 2021 | 10:01h | UTC

Fibrotic Interstitial Lung Abnormalities at 1-year Follow-up CT after Severe COVID-19 – Radiology

Related: Postacute Sequelae of COVID-19 Pneumonia: 6-month Chest CT Follow-up.

 

Commentary on Twitter

 

Guideline: Laboratory detection and initial diagnosis of monoclonal gammopathies.

6 Aug, 2021 | 09:56h | UTC

Laboratory Detection and Initial Diagnosis of Monoclonal Gammopathies: Guideline From the College of American Pathologists in Collaboration With the American Association for Clinical Chemistry and the American Society for Clinical Pathology – Archives of Pathology & Laboratory Medicine

 

ESPEN practical guideline: Clinical nutrition in surgery – “Preoperative fasting from midnight is unnecessary in most patients. Patients undergoing surgery, who are considered to have no specific risk of aspiration, shall drink clear fluids until 2 h before anesthesia. Solids shall be allowed until 6 h before anesthesia.”

6 Aug, 2021 | 09:59h | UTC

ESPEN practical guideline: Clinical nutrition in surgery – Clinical Nutrition

 

RCT: Decompression alone is non-inferior to decompression with fusion in patients with degenerative lumbar spondylolisthesis.

6 Aug, 2021 | 09:54h | UTC

Decompression with or without Fusion in Degenerative Lumbar Spondylolisthesis – New England Journal of Medicine

Commentary: Decompression Noninferior for Degenerative Spondylolisthesis – HealthDay

 

Review: Rational fluid resuscitation in sepsis for the hospitalist.

6 Aug, 2021 | 09:53h | UTC

A Narrative Review Rational Fluid Resuscitation in Sepsis for the Hospitalist: A Narrative Review – Mayo Clinic Proceedings

 

Mammographic features are associated with cardiometabolic disease risk and mortality.

6 Aug, 2021 | 09:04h | UTC

Mammographic features are associated with cardiometabolic disease risk and mortality – European Heart Journal

 

Viewpoint: Aligning payments, services, and quality in primary care.

6 Aug, 2021 | 09:08h | UTC

Aligning Payments, Services, and Quality in Primary Care – JAMA (free for a limited period)

 

M-A: Pharmacotherapy for the prevention of chronic pain after surgery in adults.

6 Aug, 2021 | 09:51h | UTC

Pharmacotherapy for the Prevention of Chronic Pain after Surgery in Adults: An Updated Systematic Review and Meta-analysis – Anesthesiology

 

Commentary on Twitter

 

Researchers tell doctors to avoid routine urinary tests for older patients with delirium.

6 Aug, 2021 | 09:01h | UTC

Researchers tell doctors to avoid routine urinary tests for older patients with delirium – Johns Hopkins University School of Medicine

Original article: Things We Do for No Reason™: Obtaining Urine Testing in Older Adults With Delirium Without Signs or Symptoms of Urinary Tract Infection – Journal of Hospital Medicine ($)

 

Commentary on Twitter (thread – click for more)

 

Stay Updated in Your Specialty

Telegram Channels
Free

WhatsApp alerts 10-day free trial

No spam, just news.