All Posts
Guideline: Endoscopy in patients on antiplatelet or anticoagulant therapy.
10 Aug, 2021 | 08:59h | UTC
ACOG Guideline: Medically indicated late-preterm and early-term deliveries.
10 Aug, 2021 | 08:56h | UTC
Giving and taking: ethical treatment assignment in controlled trials.
10 Aug, 2021 | 08:52h | UTCGiving and taking: ethical treatment assignment in controlled trials. – The James Lindt Library
Commentary on Twitter
It was a pleasure and an honour to collaborate with @iainchalmersTTi in writing this piece https://t.co/TP66e4FAOd on ethical issue in treatment assignment in clinical trials. #clinicaltrials
— Stephen John Senn (@stephensenn) August 9, 2021
Systematic Review: Non-invasive ventilation used at night by people with COPD.
10 Aug, 2021 | 08:53h | UTCOriginal review: Chronic non‐invasive ventilation for chronic obstructive pulmonary disease – Cochrane Library
Secondary analysis of RCT finds Dapagliflozin is safe for patients with stage 4 chronic kidney disease.
10 Aug, 2021 | 08:51h | UTCCommentaries:
No Increase in Risk With Dapagliflozin in Patients With Stage 4 CKD – HealthDay
Update on medical management of acute hip fracture.
10 Aug, 2021 | 08:50h | UTCUpdate on medical management of acute hip fracture – Cleveland Clinical Journal of Medicine
Commentary on Twitter
Nice review of Periop mgmt for hip Fx. Uses a modified CCS guideline approach-no stress testing,bypass BNP as pts are high risk,postop co-mgmt +troponin. Also discusses other aspects. Major take home point – AVOID DELAYING SURGERY or mortality increases. https://t.co/5DATCuKuqU
— Steven Cohn, MD (@preopconsult) August 9, 2021
Review: Diseases and complications of the puerperium.
10 Aug, 2021 | 08:46h | UTCDiseases and Complications of the Puerperium – Deutsches Ärzteblatt International
Plant-based diets protective against CVD in two cohort studies.
10 Aug, 2021 | 08:48h | UTCPlant-Based Diets Protective Against CVD in Two Studies – TCTMD
Original study 2: Plant‐Centered Diet and Risk of Incident Cardiovascular Disease During Young to Middle Adulthood – Journal of the American Heart Association
Evidence-based approach to nailbed injuries: ED presentations, evaluation, and management.
10 Aug, 2021 | 08:47h | UTCEvidence-based Approach to Nailbed Injuries: ED Presentations, Evaluation, and management – emDocs
Interactive infographic: Data shows how rare severe breakthrough Covid infections are.
9 Aug, 2021 | 00:01h | UTCData shows how rare severe breakthrough Covid infections are – NBC News
Commentary on Twitter
Very good interactive infographic for impact of vaccination in 2021 by state https://t.co/HAfYYPX9FI by @NBCNews @seenigel @ChicagoEl @pdrbarquinha @jiachuanwu @NBCNewsGraphics
Here for California: Hospitalizations, deaths and infections pic.twitter.com/83Hxl2x2gm— Eric Topol (@EricTopol) August 7, 2021
RCT: Safety and immunogenicity of heterologous vs. homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine.
9 Aug, 2021 | 00:06h | UTCInvited commentary: Optimising SARS-CoV-2 vaccination schedules – The Lancet
Related: Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination (several articles on the subject)
Commentary on Twitter
Just published @TheLancet
A randomized mix and match trial of AZ and Pfizer vaccination in >800 people shows that mixing is safe and can engender at least as good, if not better, immune response https://t.co/V40Dy59Ia8 by @XinxueLiu and colleagues pic.twitter.com/tKl59LFz4i— Eric Topol (@EricTopol) August 6, 2021
Bullous autoimmune dermatoses: clinical features, diagnostic evaluation, and treatment options.
10 Aug, 2021 | 08:44h | UTCBullous Autoimmune Dermatoses – Deutsches Ärzteblatt International
COVID: WHO calls for moratorium on booster shots – is it justifiable?
8 Aug, 2021 | 23:54h | UTCCOVID: WHO calls for moratorium on booster shots – is it justifiable? – The Conversation
Related: Covid: WHO calls for booster pause to vaccinate poorer nations.
Commentary on Twitter
The authors put it well: Even if affluent countries prioritize boosters for the vulnerable, 'the degree of additional benefit…is uncertain.' Yet we know 'vaccines could do a huge amount of good for the large number of vulnerable ppl who've not yet received a single dose.' https://t.co/6qNV6pzDDk
— Tedros Adhanom Ghebreyesus (@DrTedros) August 7, 2021
CDC study showed a reduced risk of reinfection with SARS-CoV-2 after covid-19 vaccination.
9 Aug, 2021 | 00:03h | UTC
Commentaries on Twitter
This is non randomized. The two biases are:
1. Behavior among those who got vaccinated likely different than those who don't
2. Likely those who didn't tested more aggressively
I would not cite this as many are doinghttps://t.co/rSkBC37uq0
— Vinay Prasad MD MPH (@VPrasadMDMPH) August 7, 2021
Study shows that full #COVIDVaccination ⬇️ likelihood of being re-infected with #COVID19 compared to those who were previously had COVID but were not vaccinated (risk ⬆️ 2.3 fold)#GetVaccinated even if you have had COVID previouslyhttps://t.co/3dF3XPxwYp
@fascinatorfun pic.twitter.com/ip6zTvNN86
— Prof Kamlesh Khunti (@kamleshkhunti) August 7, 2021
M-A: SARS-CoV-2 Setting-specific transmission rates – “Households showed the highest transmission rates, with a pooled secondary attack rates of 21.1%”.
8 Aug, 2021 | 23:57h | UTC
Commentary on Twitter
SARS-CoV-2 setting-specific transmission rates: a systematic review and meta-analysis
Households highest transmission rates, pooled SAR~21.1%. Contacts at social events~5.9%. Workplaces~1.9%. Age gradient for transmission potential in h/hold context. https://t.co/m27kkDrTgy
— Andrew Lee is heading to @andrewleedr.bsky.social (@andrewleedr) March 10, 2021
COVID vaccine boosters: the most important questions.
8 Aug, 2021 | 23:52h | UTCCOVID vaccine boosters: the most important questions – Nature
Commentary on Twitter
I agree with @nataliexdean: “We just don’t have clear evidence of enough of a loss of efficacy to change our focus or distract from the main goal, which is trying to get as many people first doses” as possible." https://t.co/FEKB4vg0Dz
— Sanghyuk Shin (@sanghyuk_shin) August 6, 2021
Tokyo feared Games would spread COVID; numbers suggest that didn’t happen.
8 Aug, 2021 | 23:56h | UTCTokyo feared Games would spread COVID; numbers suggest that didn’t happen – Reuters
Commentary on Twitter
Before the #Olympics began, Japan feared that the Games might spread COVID-19, introduce new variants and overwhelm the medical system. The infection numbers from inside the Olympic 'bubble' tell a different story https://t.co/EsIxj3gsNx
— Reuters (@Reuters) August 7, 2021
More data showing one dose of Pfizer vaccine may be enough for individuals who’ve had COVID.
8 Aug, 2021 | 23:50h | UTCCommentary: One Dose of Pfizer Vaccine May Be Enough for Folks Who’ve Had COVID – HealthDay
Related:
Perspective | Is one vaccine dose enough if you’ve had COVID? What the science says.
Another study shows a single dose of mRNA vaccine may be enough for patients with previous Covid-19
Spain to give just one vaccine dose to under 55-year olds who had COVID-19
Perspective: Is one vaccine dose enough after COVID-19 infection?
France’s health authority recommends single vaccine shot for people who have had COVID-19
Covid-19: People who have had infection might only need one dose of mRNA vaccine
Commentary on Twitter
SARS-CoV-2 Antibody Responses After 1 and 2 Doses of the BNT162b2 Vaccine https://t.co/ARMdH8Yboo via @JAMANetworkOpen part of @JAMANetwork Small study but one that confirms the policy of many European countries in which one dose of vaccine is sufficient after having COVID.
— Carlos del Rio (@CarlosdelRio7) August 7, 2021
Adapting interventions to new contexts—the ADAPT guidance – “Use of interventions with a previous evidence base in new contexts might be more efficient than developing new interventions”.
8 Aug, 2021 | 23:46h | UTCAdapting interventions to new contexts—the ADAPT guidance – The BMJ
Commentary on Twitter
"Although some interventions transfer well, effectiveness and implementation often depend on the context."
This paper presents new evidence and consensus informed guidance for adapting and transferring interventions to new contextshttps://t.co/of1ojFR6VD
— The BMJ (@bmj_latest) August 8, 2021
AARC Guideline: Management of pediatric patients with oxygen in the acute care setting.
8 Aug, 2021 | 23:43h | UTC
Case report: Systemic capillary leak syndrome after ChAdOx1 nCOV-19 (Oxford–AstraZeneca) vaccination.
8 Aug, 2021 | 23:49h | UTC
Pediatric asthma: The REGAP consensus.
8 Aug, 2021 | 23:45h | UTCPediatric asthma: The REGAP consensus – Anales de Pediatría
M-A: Effect of low glycemic index or load dietary patterns on glycemic control and cardiometabolic risk factors in diabetes.
8 Aug, 2021 | 23:42h | UTCCommentary: Low glycaemic diet shows meaningful improvements for people with diabetes – The British Medical Journal
Commentary on Twitter
New #BMJResearch finds that low glycaemic index/glycaemic load dietary patterns provide small important benefits for glycaemic control and other established cardiometabolic risk factors in adults with moderately controlled type 1 and type 2 diabeteshttps://t.co/EIMXUhICee
— The BMJ (@bmj_latest) August 7, 2021
ASCO Resource-Stratified Guideline: Assessment of adult women with ovarian masses and treatment of epithelial ovarian cancer.
8 Aug, 2021 | 23:38h | UTCCommentary: ASCO Publishes Resource-Stratified Guideline on Assessment and Treatment of Ovarian Cancer – The ASCO Post
Viewpoint: Cancer as a Global Health Priority.
8 Aug, 2021 | 23:37h | UTCCancer as a Global Health Priority – JAMA (free for a limited period)