RCT: Efficacy of concurrent chemoradiotherapy with S-1 vs. radiotherapy alone for older patients with esophageal cancer.

Efficacy of Concurrent Chemoradiotherapy With S-1 vs Radiotherapy Alone for Older Patients With Esophageal Cancer: A Multicenter Randomized Phase 3 Clinical Trial – JAMA Oncology (free for a limited period)

Editorial: Primary Chemoradiotherapy for Older Patients With Esophageal Cancer (free for a limited period)

Commentary: Concurrent CRT Effective for Esophageal Cancer in Older Patients — Overall survival at 2 years significantly better versus radiotherapy alone – MedPage Today (free registration required)

Commentary on Twitter

Randomized phase 3 trial of radiation with or w/o S-1 chemo in 298 older pts (median age 77) with esophageal cancer reveals concurrent chemoradiation led to significantly improved progression-free & overall survival https://t.co/wx5FG5VDUH #GICSM pic.twitter.com/SFddL53lCi

— JAMA Oncology (@JAMAOnc) August 6, 2021