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Early data from South Africa hints Omicron variant may cause less severe Covid, but more research is needed.
5 Dec, 2021 | 23:51h | UTCOriginal report: Tshwane District Omicron Variant Patient Profile – Early Features
Fauci says early reports encouraging about omicron variant – “Thus far, it does not look like there’s a great degree of severity to it”.
5 Dec, 2021 | 23:47h | UTCFauci says Omicron variant doesn’t look severe, but ‘got to be careful’ – Associated Press
WHO has no reports yet of Omicron Covid deaths.
5 Dec, 2021 | 23:48h | UTCWHO has no reports yet of Omicron Covid deaths – MedicalXpress
Commentary on Twitter
Despite #OmnicronVariant's global spread, the WHO says there are no Omicron deaths so far. The agency warns it may take weeks to determine how infectious the variant is, whether it causes more severe illness & how effective antivirals & vaccines are https://t.co/NSN6Ysf3gc pic.twitter.com/Wnp90HvUng
— delthia ricks 🔬 (@DelthiaRicks) December 4, 2021
Cohort Study: Among asymptomatic individuals that have undergone treadmill testing, high-grade premature ventricular contractions occurring during recovery were associated with increased risk of cardiovascular mortality.
5 Dec, 2021 | 23:42h | UTCExercise-Induced Ventricular Ectopy and Cardiovascular Mortality in Asymptomatic Individuals – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: Exercise-Induced Ventricular Ectopy and Cardiovascular Mortality – American College of Cardiology
Editorial: Emergence of new SARS-CoV-2 Variant of Concern Omicron (B.1.1.529) – highlights Africa’s research capabilities, but exposes major knowledge gaps, inequities of vaccine distribution, inadequacies in global COVID-19 response and control efforts.
5 Dec, 2021 | 23:46h | UTC
Consensus on Practical Management of Parathyroid Disorders in Adults and in Pregnancy.
5 Dec, 2021 | 23:43h | UTC
Review | Past, present, and future of radiation-induced cardiotoxicity: refinements in targeting, surveillance, and risk stratification.
5 Dec, 2021 | 23:40h | UTCVideo: Radiation Therapy and Cardiovascular Disease | JACC: CardioOncology Author Discussion
Related:
Radiation‐induced cardiovascular disease: review of an underrecognized pathology.
Short review: How to diagnose and manage radiation therapy cardiotoxicity
Cohort Study: Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients with Lung Cancer
Review: Preprocedural fasting for contrast-enhanced CT (CECT) – “Traditional preparatory fasting policy prior to CECT lacks methodologically acceptable evidence”.
5 Dec, 2021 | 23:29h | UTC
The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019.
5 Dec, 2021 | 23:09h | UTCInvited Commentary: Burden of cancer in adolescents and young adults – The Lancet Oncology
Pictorial Review: Spinal disorders mimicking infection.
5 Dec, 2021 | 23:10h | UTCSpinal disorders mimicking infection – Insights into Imaging
Editorial: The rationale for the recommendations of the European Pediatric Fasting Guideline – “the authors of the 2021 ESAIC pediatric guideline have found reasons to recommend reductions to the minimum fasting times for infant formula to 4 h, for breast milk to 3 h and for clear fluids to 1 h”.
5 Dec, 2021 | 23:26h | UTCOriginal Guideline: Pre-operative fasting in children: A guideline from the European Society of Anaesthesiology and Intensive Care – European Journal of Anesthesiology
Related:
Pro-Con Debate: 1- vs 2-Hour Fast for Clear Liquids Before Anesthesia in Children.
Association of resting heart rate with cognitive decline and dementia in older adults: A population-based cohort study.
5 Dec, 2021 | 23:17h | UTCNews Release: Elevated heart rate linked to increased risk of dementia – Karolinska Intitutet
[Preprint] Preliminary data points to increased risk of SARS-CoV-2 reinfection associated with the emergence of Omicron variant in South Africa.
3 Dec, 2021 | 10:29h | UTCCommentaries:
Global Omicron COVID cases rise as evidence for immune escape grows – CIDRAP
Omicron seems to carry higher Covid reinfection risk, says South Africa – The Guardian
Reinfections three times more likely with Omicron: S. African research – MedicalXpress
Commentary from the author on Twitter (thread – click for more)
[Thread] We have updated our preprint on SARS-CoV-2 reinfection trends in South Africa to include data through late November. @hivepi @jd_mathbio @carivs @Dr_Groome @nicd_sa #SACEMAhttps://t.co/yvIRtfQH6I#notyetpeerreviewed https://t.co/EKr8fgJVba
— Juliet Pulliam, PhD (@jrcpulliam@mathstodon.xyz) (@jrcpulliam) December 2, 2021
Discordant and inappropriate discordant recommendations in consensus and evidence based guidelines: empirical analysis.
5 Dec, 2021 | 23:14h | UTCEditorial: A moratorium on strong recommendations is needed – The BMJ
Commentary: Can we trust strong recommendations based on low quality evidence? – The BMJ
Commentary on Twitter
NEW research finds that consensus based guidelines produce more recommendations violating the evidence based medicine principles than evidence based guidelines https://t.co/8eCGZfiNZ3
— The BMJ (@bmj_latest) November 28, 2021
RCT: Long-term outcomes with Nivolumab plus Ipilimumab or Nivolumab alone vs. Ipilimumab in patients with advanced melanoma.
5 Dec, 2021 | 23:07h | UTCEditorial: CheckMate-067: Raising the Bar for the Next Decade in Oncology – Journal of Clinical Oncology
Original Study: #ESMO19 – Randomized Trial: Improved Overall Survival at 5 Years with Combined Immunotherapy for Advanced Melanoma
Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic.
3 Dec, 2021 | 10:28h | UTCOmicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic – The Lancet
Commentary on Twitter
NEW—Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic
In a Comment, @ProfAbdoolKarim provides preliminary indications on transmissibility, severity, and immune escape from what is known about #Omicron's mutations. https://t.co/fWJq2ZSlNK pic.twitter.com/ijpgirZ5wj
— The Lancet (@TheLancet) December 2, 2021
Podcast: The Omicron Variant of SARS-CoV-2.
3 Dec, 2021 | 10:21h | UTCThe Omicron Variant of SARS-CoV-2 – New England Journal of Medicine
Collection: What can the world learn from China’s response to covid-19?
3 Dec, 2021 | 10:24h | UTCHomepage: China’s response to Covid-19 – The BMJ
Editorial: What can the world learn from China’s response to covid-19?
Importance of public health tools in emerging infectious diseases
Non-pharmaceutical interventions during the roll out of covid-19 vaccines
Use of contact tracing, isolation, and mass testing to control transmission of covid-19 in China
Role of asymptomatic and pre-symptomatic infections in covid-19 pandemic
Effectiveness of 14 day quarantine strategy: Chinese experience of prevention and control
Cold chain logistics: a possible mode of SARS-CoV-2 transmission?
Better modelling of infectious diseases: lessons from covid-19 in China
Learning for the next pandemic: the Wuhan experience of managing critically ill people
Interactive Infographic: Visualizing SARS-CoV-2 transmission routes and mitigations.
3 Dec, 2021 | 10:26h | UTCVisualising SARS-CoV-2 transmission routes and mitigations – The BMJ
Commentary: New interactive graphic tool illustrates SARS-CoV-2 transmission routes and mitigations – News Medical
Commentary on Twitter
Is it risky to sing in a choir or eat in a small restaurant? How much difference does it make if I open windows or clean surfaces?
A new #BMJInfographic helps people decide what to do in everyday situations to protect themselves, and others, from covid-19 https://t.co/RMoEwZ9wTz pic.twitter.com/XV9ElCoOGa
— The BMJ (@bmj_latest) December 2, 2021
Omicron is supercharging the COVID vaccine booster debate – “The data are growing that booster jabs enhance protection — but their durability, impact and ability to quash the new variant are unknown”.
3 Dec, 2021 | 10:19h | UTCOmicron is supercharging the COVID vaccine booster debate – Nature
Omicron-variant border bans ignore the evidence, say scientists – “Researchers say travel restrictions in response to the newly detected coronavirus variant come too late and could even slow studies of Omicron”.
3 Dec, 2021 | 10:20h | UTCOmicron-variant border bans ignore the evidence, say scientists – Nature
How bad is Omicron? What scientists know so far.
3 Dec, 2021 | 10:18h | UTCHow bad is Omicron? What scientists know so far – Nature
Opinion | Omg, Omicron! Why it’s too soon to panic about COVID vaccines and the new variant.
3 Dec, 2021 | 10:16h | UTCOmg, Omicron! Why it’s too soon to panic about COVID vaccines and the new variant – The Conversation
Review: Interventions to optimize antimicrobial stewardship.
3 Dec, 2021 | 10:11h | UTC
Germany on Thursday announced a nationwide lockdown for the unvaccinated.
3 Dec, 2021 | 10:14h | UTCGermany locks down unvaccinated people, as leaders plan to make shots compulsory – CNN
See also: Germany locks unvaccinated out of public life; mandate looms – Associated Press