Open access
Open access
Powered by Google Translator Translator

All Posts

Practical recommendations on quantifying and interpreting treatment effects in the presence of terminal competing risks.

3 Dec, 2021 | 10:07h | UTC

Practical Recommendations on Quantifying and Interpreting Treatment Effects in the Presence of Terminal Competing Risks: A Review – JAMA Cardiology (free for a limited period)

 

Commentary on Twitter

 

Randomized clinical trials in critical care: past, present and future.

3 Dec, 2021 | 10:10h | UTC

Randomised clinical trials in critical care: past, present and future – Intensive Care Medicine

 

Commentary on Twitter

 

ESGE Guideline: Endoscopic management of enteral tubes in adult patients.

3 Dec, 2021 | 10:02h | UTC

Endoscopic management of enteral tubes in adult patients: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Endoscopy

Part 1: Definitions and indications.

Part 2: Peri- and post-procedural management.

 

Perspective | Harms versus benefits in medicine: not just a decision for experts.

3 Dec, 2021 | 10:05h | UTC

Harms versus benefits in medicine: not just a decision for experts – The Conversation

 

Systematic Review: Phototherapy for atopic eczema.

3 Dec, 2021 | 10:03h | UTC

Phototherapy for atopic eczema – Cochrane Library

Summary: What are the benefits and risks of visible light therapy for treating atopic eczema (also known as eczema or atopic dermatitis)? – Cochrane Library

 

Commentary on Twitter

https://twitter.com/CochraneUK/status/1457046637134630920

 

The Omicron Variant Is a Mystery. Here’s How Science Will Solve It – “So far, panic about the new Covid variant has outpaced actual information. Here’s what scientists around the world are trying to uncover”.

2 Dec, 2021 | 10:08h | UTC

The Omicron Variant Is a Mystery. Here’s How Science Will Solve It – Wired

See also the latest articles on the subject:

Where did ‘weird’ Omicron come from? – Science

We can prevail over Omicron. We just need to use the tools we have – The Guardian

How South African Researchers Identified the Omicron Variant of COVID – The New Yorker

The omicron variant has been found in 23 countries – NPR

These countries have found cases of the Omicron Covid-19 variant so far – CNN

Scientists say it will take weeks to tell how dangerous Omicron really is. Here’s why – CNN

Coronavirus variants: Here’s what we know – CNN

To catch variants like omicron, the world needs to sequence way more virus genes – Vox

Omicron’s Best- and Worst-Case Scenarios – The Atlantic

Africa: tackle HIV and COVID-19 together – Nature

Omicron Travel Bans Violate International Health Rules and Decimate Southern Africa’s Fragile Tourism Industry – Health Policy Watch

The mystery of where omicron came from — and why it matters – NPR

A reason for optimism on Omicron: Our immune systems are not blank slates – STAT

Omicron – Science-Based Medicine

Covid: Omicron may require ‘very stringent response’, say Sage scientists – BBC

WHO warns against Omicron travel bans as nations shut borders – MedicalXpress

Israeli doctor believes he caught Omicron variant of Covid in London – The Guardian

First case of Omicron coronavirus variant identified in the U.S. – STAT

 

Retrospective Cohort Study: Except for Rituximab, most immunosuppressive medicines were not associated with increased risk of mechanical ventilation or death in patients hospitalized with Covid-19.

2 Dec, 2021 | 10:07h | UTC

Long-term use of immunosuppressive medicines and in-hospital COVID-19 outcomes: a retrospective cohort study using data from the National COVID Cohort Collaborative – The Lancet Rheumatology

Commentaries:

What does endemic COVID-19 mean for the future of rituximab? – The Lancet Rheumatology

Outcomes for hospitalized COVID-19 patients taking immunosuppressive medications similar to non-immunosuppressed patients, study finds – Johns Hopkins University Bloomberg School of Public Health

Study: Immune-suppressed not at higher risk of poor COVID outcomes – CIDRAP

 

Commentary on Twitter

 

AAP Clinical Report | Tuberculosis Infection in Children and Adolescents.

2 Dec, 2021 | 09:58h | UTC

Tuberculosis Infection in Children and Adolescents: Testing and Treatment – Pediatrics

 

Systematic Review: Models of COVID-19 vaccine prioritization – “for countries seeking to minimize deaths, prioritizing vaccination of senior adults was the optimal strategy and for countries seeking to minimize cases the young were prioritized”.

2 Dec, 2021 | 10:02h | UTC

Models of COVID-19 vaccine prioritisation: a systematic literature search and narrative review – BMC Medicine

 

World Health Assembly agrees to launch process to develop historic global accord on pandemic prevention, preparedness and response.

2 Dec, 2021 | 10:03h | UTC

World Health Assembly agrees to launch process to develop historic global accord on pandemic prevention, preparedness and response – World Health Organization

Commentary: Standing Ovation as WHO Member States Commit to Negotiating New Pandemic Accord – Health Policy Watch

 

Fluvoxamine for the early treatment of SARS-CoV-2 Infection: a review of current evidence.

2 Dec, 2021 | 10:04h | UTC

Fluvoxamine for the Early Treatment of SARS-CoV-2 Infection: A Review of Current Evidence – Drugs

Related:

RCT: Early treatment with fluvoxamine reduced the risk of emergency care and hospitalization among patients with COVID-19.

[Preprint] RCT: Fluvoxamine reduced the risk for ER visits and hospitalization among patients with Covid-19.

Opinion | Could this be our first effective, inexpensive, widely available outpatient treatment for COVID-19? (It’s fluvoxamine).

Preliminary study shows fluvoxamine may reduce clinical deterioration in outpatients with symptomatic COVID-19

 

ERS guideline on non-CPAP therapies for obstructive sleep apnea.

2 Dec, 2021 | 09:56h | UTC

European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea – European Respiratory Review

 

AHA Scientific Statement: Supporting physical activity in patients and populations during life events and transitions.

2 Dec, 2021 | 09:53h | UTC

Supporting Physical Activity in Patients and Populations During Life Events and Transitions: A Scientific Statement From the American Heart Association – Circulation

News Release: Major life events influence level of physical activity, may negatively impact heart health – American Heart Association

 

RCT: Cytoreductive surgery for relapsed ovarian cancer.

2 Dec, 2021 | 09:51h | UTC

Randomized Trial of Cytoreductive Surgery for Relapsed Ovarian Cancer – New England Journal of Medicine

 

The ‘ten commandments’ for the 2021 ESC Guidelines on CVD prevention.

2 Dec, 2021 | 09:45h | UTC

The ‘ten commandments’ for the 2021 ESC Guidelines on CVD prevention – European Heart Journal

Original Article: #ESCCongress – 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice.

 

Guideline: Management of ureteral calculi.

2 Dec, 2021 | 09:54h | UTC

Canadian Urological Association guideline: Management of ureteral calculi – Abridged version – Canadian Urological Association Journal

Related Guidelines:

Renal and ureteric stones: assessment and management – National Institute for Health and Care Excellence

Dietary and Pharmacologic Management to Prevent Recurrent Nephrolithiasis in Adults: A Clinical Practice Guideline From the American College of Physicians

Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement – Journal of Nephrology

The Urological Association of Asia clinical guideline for urinary stone disease – International Journal of Urology

 

Chronic cough: new insights and future prospects.

2 Dec, 2021 | 09:43h | UTC

Chronic cough: new insights and future prospects – European Respiratory Review

 

RCT: 21-Gene assay to inform chemotherapy benefit in node-positive breast cancer.

2 Dec, 2021 | 09:49h | UTC

21-Gene Assay to Inform Chemotherapy Benefit in Node-Positive Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 

E-cigarettes may be independently linked to erectile dysfunction.

2 Dec, 2021 | 09:44h | UTC

News Release: E-cigarettes may be independently linked to erectile dysfunction, new research finds – NYU Langone Health

Original Study: Association of E-Cigarettes with Erectile Dysfunction: The Population Assessment of Tobacco and Health Study – American Journal of Preventive Medicine

 

Cohort Study: Timing of dialysis initiation to reduce mortality and cardiovascular events in advanced chronic kidney disease.

2 Dec, 2021 | 09:47h | UTC

Timing of dialysis initiation to reduce mortality and cardiovascular events in advanced chronic kidney disease: nationwide cohort study – The BMJ

 

Commentary from the author on Twitter (thread – click for more)

 

Complete countrywide mortality in COVID patients receiving ECMO in Germany throughout the first three waves of the pandemic.

1 Dec, 2021 | 09:52h | UTC

Complete countrywide mortality in COVID patients receiving ECMO in Germany throughout the first three waves of the pandemic – Critical Care

 

WHO advice for international traffic in relation to the SARS-CoV-2 Omicron variant (B.1.1.529).

1 Dec, 2021 | 10:02h | UTC

WHO advice for international traffic in relation to the SARS-CoV-2 Omicron variant (B.1.1.529) – World Health Organization

Commentary: Over-60s, vulnerable should postpone travel due to Omicron: WHO – MedicalXpress

See also the latest articles on the subject:

Will omicron – the new coronavirus variant of concern – be more contagious than delta? A virus evolution expert explains what researchers know and what they don’t – The Conversation

WHO pleads for ‘rational’ Omicron response – MedicalXpress

Omicron: WHO warns of ‘high infection risk’ around globe – BBC

Video: Why Omicron is the most worrying Covid variant yet – video explainer – The Guardian

Doctors hope Omicron causes milder cases of Covid — but it’s still too early to say – STAT

Doctor: Many South Africans ill in surge have mild symptoms – Associated Press

New Findings Show the Omicron Variant Spread Widely At a Faster Pace Than Initially Thought – TIME

Why some researchers think the omicron variant could be the most infectious one yet – NPR

Omicron Covid variant ‘present in Europe at least 10 days ago’ – The Guardian

Netherlands says Omicron variant was already in country earlier than previously thought – CNN

Netherlands detections hint at earlier Omicron spread – CIDRAP

Epidemiologist awaits clearer picture on omicron – Harvard University

Pfizer research head envisions a sprint to develop Omicron vaccine, if it’s needed – STAT

Omicron COVID variant was in Europe before South African scientists detected and flagged it to the world – CBS News

Moderna boss predicts current vaccines may be less effective against Omicron – The Guardian

Wealthy nations starved the developing world of vaccines. Omicron shows the cost of this greed – The Conversation

Travel restrictions by country following the Omicron variant outbreak – CNN

 

FDA panel narrowly recommends authorization of first antiviral pill to treat COVID.

1 Dec, 2021 | 09:56h | UTC

FDA panel narrowly recommends authorization of first antiviral pill to treat COVID – STAT

See also: An FDA panel supports Merck COVID drug in mixed vote – NPR

Related:

[Press release – not published yet] Merck’s new Covid-19 pill Molnupiravir updated data shows reduced efficacy (30%) for preventing hospitalization and death compared to initial results (50%). Absolute risk reduction of hospitalization and death fell from 7% to 3%.

8 lingering questions about the new Covid pills from Merck and Pfizer.

COVID antiviral pills: what scientists still want to know – “Drugs like Molnupiravir and Paxlovid could change the course of the pandemic if clinical trial results hold up in the real world”.

[Press release – not published yet] RCT: Pfizer’s novel Covid-19 oral antiviral treatment candidate reduced risk of hospitalization or death by 89% in interim analysis of phase 2/3 EPIC-HR study.

A prominent virologist warns new COVID-19 pill could unleash dangerous mutants. Others see little cause for alarm.

The U.K. approves Merck’s COVID-19 antiviral pill, calling it a world first.

Merck to allow other nations to produce new COVID-19 antiviral.

Video: Merck’s Covid pill could transform treatment. Here’s how it works.

How antiviral pill Molnupiravir shot ahead in the COVID drug hunt.

What we know — and don’t know — about Merck’s new Covid-19 pill.

[Press release – not published yet] Merck announces oral antiviral Molnupiravir reduced the risk of hospitalization or death by approximately 50 Percent compared to placebo for patients with mild or moderate COVID-19.

Merck’s Covid-19 pill is great news but may not be a game-changer.

Video | A Pill For COVID? A Doctor Explains Molnupiravir.

 

Ending the COVID-19 Pandemic Hinges on Trust: Science alone won’t pull us out of the pandemic.

1 Dec, 2021 | 09:47h | UTC

Ending the COVID-19 Pandemic Hinges on Trust – Think Global Health

 

Commentary on Twitter

 

Using wearable data, a real-time alerting system can be used for the early detection of Covid-19 and other stress events.

1 Dec, 2021 | 09:59h | UTC

Real-time alerting system for COVID-19 and other stress events using wearable data – Nature Medicine

Commentary: Scientists develop a smartwatch-based device for early detection of COVID-19 – News Medical

 

Commentary on Twitter

 

Stay Updated in Your Specialty

Telegram Channels
Free

WhatsApp alerts 10-day free trial

No spam, just news.