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What Is of Recent Interest in Cardiac Imaging?: Insights From the JACC Family of Journals.

8 Dec, 2021 | 09:54h | UTC

What Is of Recent Interest in Cardiac Imaging?: Insights From the JACC Family of Journals – Journal of the American College of Cardiology

 

Raising awareness for time-limited trial discussion upon ICU triage and admission.

8 Dec, 2021 | 09:57h | UTC

Raising awareness for time-limited trial discussion upon ICU triage and admission – Intensive Care Medicine (if the link is paywalled, try this one)

 

Commentary on Twitter

 

M-A: Efficacy and safety associated with immune checkpoint inhibitors in unresectable hepatocellular carcinoma.

8 Dec, 2021 | 09:48h | UTC

Efficacy and Safety Associated With Immune Checkpoint Inhibitors in Unresectable Hepatocellular Carcinoma: A Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 

Evaluation and management of pelvic organ prolapse.

8 Dec, 2021 | 09:50h | UTC

Evaluation and Management of Pelvic Organ Prolapse – Mayo Clinic Proceedings

 

ESMO Clinical Practice Guideline update on the use of immunotherapy in early stage and advanced renal cell carcinoma.

8 Dec, 2021 | 09:45h | UTC

ESMO Clinical Practice Guideline update on the use of immunotherapy in early stage and advanced renal cell carcinoma – Annals of Oncology

 

Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

8 Dec, 2021 | 09:47h | UTC

Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up – Annals of Oncology

 

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

7 Dec, 2021 | 10:19h | UTC

Clinically Suspected Myocarditis Temporally Related to COVID-19 Vaccination in Adolescents and Young Adults – Circulation

News Release: Young people recover quickly from rare myocarditis side effect of COVID-19 vaccine – American Heart Association

 

Study shows increased immunogenicity of extended mRNA SARS-CoV-2 vaccine dosing intervals.

7 Dec, 2021 | 10:21h | UTC

Immunogenicity of Extended mRNA SARS-CoV-2 Vaccine Dosing Intervals – JAMA

 

Commentary on Twitter (thread – click for more)

 

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

7 Dec, 2021 | 10:23h | UTC

The Risk of Postoperative Complications following Major Elective Surgery in Active or Resolved COVID-19 in the United States – Annals of Surgery

Related:

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

 

The world has the tools to end the coronavirus pandemic. They’re not being used properly.

7 Dec, 2021 | 10:15h | UTC

The world has the tools to end the coronavirus pandemic. They’re not being used properly – CNN

 

Care of older people and people requiring palliative care with COVID-19: guidance from the Australian National COVID-19 Clinical Evidence Taskforce.

7 Dec, 2021 | 10:12h | UTC

Care of older people and people requiring palliative care with COVID-19: guidance from the Australian National COVID-19 Clinical Evidence Taskforce – Medical Journal of Australia

 

WHO Report: More malaria cases and deaths in 2020 linked to COVID-19 disruptions.

7 Dec, 2021 | 08:55h | UTC

News Release: More malaria cases and deaths in 2020 linked to COVID-19 disruptions – World Health Organization

Report: World Malaria Report 2021 – World Health Organization

Commentaries:

More people died of malaria in 2020 than in 2019. Here’s why – NPR

Malaria kills 180,000 more people annually than previously thought, says WHO – The Guardian

 

Commentary on Twitter (thread – click for more)

 

Perspective | ‘It’s misinformation at worst.’ Weak health studies can do more harm than good, scientists say.

7 Dec, 2021 | 10:17h | UTC

‘It’s misinformation at worst.’ Weak health studies can do more harm than good, scientists say – Science

 

Review of 4,470 cases of Multisystem Inflammatory Syndrome in Children in the US.

7 Dec, 2021 | 10:08h | UTC

Multisystem Inflammatory Syndrome in Children—United States, February 2020–July 2021 – Clinical Infectious Diseases

Related:

WHO issues guidelines on the treatment of children with multisystem inflammatory syndrome associated with COVID-19.

An Update on Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2.

Ten Things to Know About Multisystem Inflammatory Syndrome in Children (MIS-C).

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.

Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.

Cohort study showed good recovery for most children 6 months after Pediatric Inflammatory Multisystem Syndrome (PIMS-TS) associated with SARS-CoV-2.

Epidemiology of Multisystem Inflammatory Syndrome in Children: A Step Closer to Understanding Who, Where, and When

Neurologic involvement in children and adolescents with COVID-19 or Multisystem Inflammatory Syndrome

Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children

Differences in characteristics and outcomes of children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C) vs. severe acute COVID-19

Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)

SR: Multisystem inflammatory syndrome in children related to COVID-19

Observational study: The combination of Immunoglobulins + Methylprednisolone was associated with a better course of fever compared to Immunoglobulins alone in Multisystem Inflammatory Syndrome in children

ACR Guidance for pediatric patients with multisystem inflammatory syndrome in children associated with SARS‐CoV‐2

New systematic review of Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 infection summarizes the clinical features, management, and outcomes of the disease, showing favorable outcomes for the majority of children

 

IDSA Guidance on the Treatment of AmpC β-lactamase-Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections.

7 Dec, 2021 | 08:49h | UTC

Infectious Diseases Society of America Guidance on the Treatment of AmpC β-lactamase-Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections – Clinical Infectious Diseases

 

S2k guideline: diagnosis and treatment of carbon monoxide poisoning.

7 Dec, 2021 | 08:48h | UTC

S2k guideline diagnosis and treatment of carbon monoxide poisoning – German Medical Science

 

A qualitative study identified a wide variation of expected impacts of the 626 low-value services spotted by the US Choosing Wisely recommendations.

7 Dec, 2021 | 08:39h | UTC

Longitudinal Content Analysis of the Characteristics and Expected Impact of Low-Value Services Identified in US Choosing Wisely Recommendations – JAMA Internal Medicine (free for a limited period)

Editorial: The Next Frontier of Less Is More—From Description to Implementation – JAMA Internal Medicine (free for a limited period)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 

Clinical pharmacology of cytotoxic drugs in neonates and infants: Providing evidence-based dosing guidance.

7 Dec, 2021 | 08:47h | UTC

Clinical pharmacology of cytotoxic drugs in neonates and infants: Providing evidence-based dosing guidance – European Journal of Cancer

 

RCT: Maribavir for refractory Cytomegalovirus infections with or without resistance post-transplant.

7 Dec, 2021 | 08:37h | UTC

Maribavir for Refractory Cytomegalovirus Infections With or Without Resistance Post-Transplant: Results from a Phase 3 Randomized Clinical Trial – Clinical Infectious Diseases

 

Clinical Review: Management of pneumonia in critically ill patients.

7 Dec, 2021 | 08:41h | UTC

Management of pneumonia in critically ill patients – The BMJ

 

Systematic Review: Current practices of management of maternal and congenital Cytomegalovirus infection during pregnancy after a maternal primary infection occurring in first trimester of pregnancy.

7 Dec, 2021 | 08:35h | UTC

Current practices of management of maternal and congenital Cytomegalovirus infection during pregnancy after a maternal primary infection occurring in first trimester of pregnancy: Systematic review – PLOS One

 

M-A: Major adverse events related to endoscopic or laparoscopic procedures in achalasia.

7 Dec, 2021 | 08:33h | UTC

Major adverse events related to endoscopic or laparoscopic procedures in achalasia. A systematic review and meta-analysis – Revista de Gastroenterología de México

 

Six different COVID-19 boosters are safe and increase immunity when given after two doses of AstraZeneca or Pfizer-BioNTech, with significant variations in immune responses, UK trial shows.

5 Dec, 2021 | 23:57h | UTC

News Release: Six different COVID-19 boosters are safe and increase immunity when given after two doses of AstraZeneca or Pfizer-BioNTech, with large variations in immune responses, UK trial shows – The Lancet

Original Study: Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial – The Lancet

Commentaries:

Six different COVID-19 boosters induce variable immune response – CIDRAP

Covid booster shots significantly strengthen immunity, trial finds – The Guardian

Expert reaction to COV-BOOST study investigating safety and immunogenicity of seven COVID-19 vaccines as a third dose following two doses of either Oxford-AstraZeneca or Pfizer – Science Media Centre

 

Commentary on Twitter

 

Systematic Review: What are the benefits and risks of electrical spinal cord and dorsal root ganglion stimulation for the treatment of chronic pain in adults?

7 Dec, 2021 | 08:31h | UTC

Summary: What are the benefits and risks of electrical spinal cord and dorsal root ganglion stimulation for the treatment of chronic pain in adults? – Cochrane Library

Original study: Implanted spinal neuromodulation interventions for chronic pain in adults – Cochrane Library

 

European data on Omicron: Out of 109 cases confirmed so far, all cases for which there is available information on severity were either asymptomatic or mild.

5 Dec, 2021 | 23:50h | UTC

Epidemiological update: Omicron variant of concern (VOC) – data as of 3 December 2021 (12.00) – European Centre for Disease Prevention and Control

 

Commentary on Twitter:

 

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