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Outcomes associated with caustic ingestion among 1198 adults in a national prospective database in France.

9 Dec, 2021 | 10:19h | UTC

Outcomes Associated With Caustic Ingestion Among Adults in a National Prospective Database in France – JAMA Surgery (free for a limited period)

Invited commentary: Caustic Ingestion—The Haves and the Have Nots (free for a limited period)

Commentary on Twitter

Study provides nation-wide data regarding in-hospital patients' outcomes after caustic ingestion. Severity of ingestion and hospital volume are associated with mortality. If feasible, low volume hospitals should transfer patients to larger centers https://t.co/VbX1jhGbjJ

— JAMA Surgery (@JAMASurgery) December 8, 2021

M-A: Effects of immediate or early oral feeding on acute pancreatitis.

9 Dec, 2021 | 10:14h | UTC

Effects of immediate or early oral feeding on acute pancreatitis: A systematic review and meta-analysis – Pancreatology

Review: Current issues in the use of opioids for the management of postoperative pain.

9 Dec, 2021 | 10:18h | UTC

Current Issues in the Use of Opioids for the Management of Postoperative Pain: A Review – JAMA Surgery (free for a limited period)

Recommended standards for the performance of transesophageal echocardiographic screening for structural heart intervention.

9 Dec, 2021 | 10:11h | UTC

Commentary on Twitter

New TEE in Structural Heart Intervention Guideline Now Available Online: https://t.co/BtqTHmSNHY
Lead author @hahn_rt will present 2 webinars on this guideline Dec. 15 & 17. Save the date. Registration will open soon! pic.twitter.com/GL9ndSini6

— American Society of Echocardiography (@ASE360) November 18, 2021

New Zealand to ban smoking for next generation in bid to outlaw habit by 2025 – “New legislation means the legal smoking age will increase every year, to create a smoke-free generation of New Zealanders”.

9 Dec, 2021 | 10:12h | UTC

New Zealand to ban smoking for next generation in bid to outlaw habit by 2025 – The Guardian

Systematic Review: Benefits and harms of annual, biennial, or triennial breast cancer mammography screening for women at average risk of breast cancer.

9 Dec, 2021 | 10:08h | UTC

Benefits and harms of annual, biennial, or triennial breast cancer mammography screening for women at average risk of breast cancer: a systematic review for the European Commission Initiative on Breast Cancer (ECIBC) – British Journal of Cancer

Commentary on Twitter (thread – click for more)

https://twitter.com/ccaneloa/status/1464655542010494981

Update in the diagnosis and management of acute pulmonary embolism for the non-respiratory physician.

9 Dec, 2021 | 10:00h | UTC

Update in the diagnosis and management of acute pulmonary embolism for the non-respiratory physician – Clinical Medicine Journal

Modern day management of a unilateral pleural effusion.

9 Dec, 2021 | 09:58h | UTC

Modern day management of a unilateral pleural effusion – Clinical Medicine Journal

Blood sugar targets in surgical intensive care: management and special considerations in patients with diabetes.

9 Dec, 2021 | 10:06h | UTC

Blood Sugar Targets in Surgical Intensive Care – Deutsches Ärzteblatt International

Interstitial lung disease on the acute take for the non-respiratory physician.

9 Dec, 2021 | 09:57h | UTC

Interstitial lung disease on the acute take for the non-respiratory physician – Clinical Medicine Journal

Review: Diagnosis and management of non-cystic fibrosis bronchiectasis.

9 Dec, 2021 | 09:53h | UTC

Diagnosis and management of non-cystic fibrosis bronchiectasis – Clinical Medicine Journal

Review: Lung cancer for the non-respiratory physician.

9 Dec, 2021 | 09:54h | UTC

Lung cancer for the non-respiratory physician – Clinical Medicine Journal

[Preprint] Risk of Hospitalization, severe disease, and mortality due to COVID-19 in children with SARS-CoV-2 infection in Germany – “overall hospitalization rate associated with SARS-CoV-2 infection was 35.9 per 10,000 children, ICU admission rate was 1.7 per 10,000 and case fatality was 0.09 per 10,000”.

8 Dec, 2021 | 10:18h | UTC

Risk of Hospitalization, severe disease, and mortality due to COVID-19 and PIMS-TS in children with SARS-CoV-2 infection in Germany – medRxiv

Editorial: COVID-19 vaccines for children – “Although it is true that most children experience asymptomatic or mild disease, some will get quite sick, and a small number will die. It’s why children are vaccinated against influenza, meningitis, chickenpox, and hepatitis”.

Review: Should children under 12 years of age be vaccinated against COVID-19?

Deaths in children and young people in England after SARS-CoV-2 infection during the first pandemic year – “In total, 99.995% of children and young people with a positive SARS-CoV-2 test survived”.

WHO recommends against the use of convalescent plasma to treat COVID-19.

8 Dec, 2021 | 10:24h | UTC

News Release: WHO recommends against the use of convalescent plasma to treat COVID-19 – World Health Organization

See Guidance: WHO’s living guidelines on COVID-19 therapeutics

Infographic: A living WHO guideline on drugs for covid-19 – The BMJ

Commentary on Twitter (thread – click for more)

Convalescent plasma is a transfusion of blood plasma from someone who has recovered from #COVID19, and is used as a treatment for COVID19 https://t.co/Bobq7OTDGq pic.twitter.com/pfO1sFvUpJ

— World Health Organization (WHO) (@WHO) December 7, 2021

A first, small study suggests Omicron is a larger threat to Covid-19 immunity than other variants.

8 Dec, 2021 | 10:22h | UTC

A first, small study suggests Omicron is a larger threat to Covid-19 immunity than other variants – STAT

Original Study: SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection – medRxiv

Commentary from the author on Twitter (thread – click for more)

We have completed our first experiments on neutralization of Omicron by Pfizer BNT162b2 vaccination elicited immunity

Manuscript available at https://t.co/rGaEB9GdmS

and should be available on medRxiv in the coming days

— Alex Sigal (@sigallab) December 7, 2021

RCT: In patients with severe Covid-19, high-flow oxygen therapy reduced the likelihood of invasive mechanical ventilation and decreased the time to clinical recovery compared to conventional oxygen therapy.

8 Dec, 2021 | 10:15h | UTC

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19: A Randomized Clinical Trial – JAMA

Non-invasive respiratory support in the management of acute COVID-19 pneumonia: considerations for clinical practice and priorities for research – “The two randomized controlled trials indicate superiority of non-invasive ventilation over high-flow nasal oxygen in reducing the need for intubation”.

[Preprint] RCT: non-invasive respiratory strategies in acute respiratory failure in patients with COVID-19 – CPAP reduced the composite outcome of intubation or death within 30 days; high-flow nasal oxygenation was not associated with better outcomes.

Phase 2 RCT: Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule.

8 Dec, 2021 | 10:12h | UTC

Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single-centre, double-blind, randomised, placebo-controlled phase 2 clinical trials – The Lancet Infectious Diseases

Invited Commentary: Booster doses for inactivated COVID-19 vaccines: if, when, and for whom – The Lancet Infectious Diseases

Video | COVID-19 Update: Omicron Variant.

8 Dec, 2021 | 10:09h | UTC

COVID-19 Update: Omicron Variant – JAMA

Beyond Omicron: what’s next for COVID’s viral evolution.

8 Dec, 2021 | 10:06h | UTC

Beyond Omicron: what’s next for COVID’s viral evolution – Nature

AAN Practice Advisory: Antiseizure medication withdrawal in patients who are seizure-free.

8 Dec, 2021 | 09:59h | UTC

Antiseizure Medication Withdrawal in Seizure-Free Patients: Practice Advisory Update Summary: Report of the AAN Guideline Subcommittee – Neurology

Prevention and management of hyperkalemia in patients treated with renin–angiotensin–aldosterone system inhibitors.

8 Dec, 2021 | 09:58h | UTC

Prevention and management of hyperkalemia in patients treated with renin–angiotensin–aldosterone system inhibitors – Canadian Medical Association Journal

Editorial: Omicron is bad, but the global response is worse – “The pandemic will not end while vaccine equity keeps getting pushed to the margins”.

8 Dec, 2021 | 10:07h | UTC

Omicron is bad but the global response is worse – Nature

ESC Position Paper: Optimal follow-up after acute pulmonary embolism.

8 Dec, 2021 | 10:02h | UTC

Optimal follow-up after acute pulmonary embolism: a position paper of the European Society of Cardiology Working Group on Pulmonary Circulation and Right Ventricular Function, in collaboration with the European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology, endorsed by the European Respiratory Society – European Heart Journal

Commentary on Twitter

Do you routinely discuss how/when to resume sporting activities and traveling with your PE patients? Or future cardiovascular risk? Check this recent ESC/ERS position paper on optimal follow-up of acute PE for these and other key aspects of counselling: https://t.co/KEQ7FnFwXX

— Erik Klok (@Erik_Klok_MD) December 7, 2021