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Hematology, the ASH Education Program – series of review articles with clinical cases published annually by the American Society of Hematology.
13 Dec, 2021 | 08:45h | UTCHomepage: Hematology, the ASH Education Program
Review: Endometrial cancer.
13 Dec, 2021 | 08:43h | UTCEndometrial cancer – Nature Reviews Disease Primers (free for a limited period – if the link is paywalled, try this one)
Infographic: Endometrial cancer (free for a limited period – if the link is paywalled, try this one)
SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact.
10 Dec, 2021 | 10:23h | UTC
Commentary on Twitter
SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact https://t.co/dd91AkYmu4 pic.twitter.com/1ByzLeTdlh
— Nature Rev Immunol (@NatRevImmunol) December 7, 2021
Cohort Study: Association of bilateral salpingo-oophorectomy with all cause and cause specific mortality.
13 Dec, 2021 | 08:42h | UTC
Commentary on Twitter
This observational study found that bilateral salpingo-oophorectomy at non-malignant hysterectomy appeared to be associated with increased all cause mortality in women aged <50 years, but not in those aged ≥50 years https://t.co/I0b9nrht9V
— The BMJ (@bmj_latest) December 11, 2021
Editorial | Emerging SARS-CoV-2 variants: shooting the messenger.
10 Dec, 2021 | 10:19h | UTCEmerging SARS-CoV-2 variants: shooting the messenger – The Lancet Infectious Diseases
Commentary on Twitter
"Omicron is the latest variant but is unlikely to be the last. We cannot risk disincentivising nations from alerting the world to new variants. In fact, globally, we would benefit from upscaling genomic surveillance" @TheLancetInfDis #IDTwitter #MedEd https://t.co/3Mz6WAgsKD
— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) December 9, 2021
The emergence, genomic diversity and global spread of SARS-CoV-2.
10 Dec, 2021 | 10:21h | UTCThe emergence, genomic diversity and global spread of SARS-CoV-2 – Nature
Omicron spreads, but severe cases remain low in South Africa.
10 Dec, 2021 | 10:17h | UTCOmicron spreads but severe cases remain low in South Africa – WHO Africa
2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization.
10 Dec, 2021 | 10:11h | UTCGuideline Hub: 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization
Executive Summary: 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization
News release: Coronary Revascularization the Focus of New ACC/AHA Clinical Guideline
ACC/AHA Slide Set: 2021 ACC/AHA/SCAI Guidelines for Coronary Artery Revascularization
Top Things to Know: 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization
Key Perspectives: ACC/AHA/SCAI Coronary Revascularization Guideline
Commentary on Twitter
🆕 ACC/@American_Heart/@SCAI #ClinicalGuidelines for Coronary Artery Revascularization released today. This guideline provides a patient-centric approach to guide clinicians in the treatment of patients undergoing #Revasc. Access the full guideline here: https://t.co/rr6TI5kFzI pic.twitter.com/f3xdTFAaUi
— American College of Cardiology (@ACCinTouch) December 9, 2021
Infodemics: a new challenge for public health.
10 Dec, 2021 | 10:18h | UTCInfodemics: A new challenge for public health – Cell
See also:
What is an infodemic and how can we prevent it?
Commentary on Twitter
What pandemics and infodemics don’t have in common could help us learn how to fight them, experts suggest in a new @CellCellPress Commentary. Read more here: https://t.co/15nVCiebLI@Walter4C pic.twitter.com/7viNB9yRvR
— Cell Press (@CellPressNews) December 9, 2021
CDC chief says Omicron is ‘mild’ as early data comes in on US spread of variant.
10 Dec, 2021 | 10:14h | UTCCDC chief says Omicron is ‘mild’ as early data comes in on US spread of variant – The Guardian
M-A: Performance of the European Society of Cardiology 0/1-hour, 0/2-hour, and 0/3-hour algorithms for rapid triage of acute myocardial infarction.
10 Dec, 2021 | 10:09h | UTCPerformance of the European Society of Cardiology 0/1-Hour, 0/2-Hour, and 0/3-Hour Algorithms for Rapid Triage of Acute Myocardial Infarction: An International Collaborative Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries:
Rapid ESC hs-cTn Algorithms Best 3-Hour Protocol for MI Rule-out: Meta-analysis – TCTMD
Performance of ESC 0/1-, 0/2-, 0/3-Hour Algorithms for AMI Compared – HealthDay
Commentary on Twitter
New meta-analysis published this week confirms new algorithms proposed by @escardio for ruling out #myocardialinfarction are more accurate than the previously preferred diagnostic tool: https://t.co/lAnozWXuOF pic.twitter.com/v2JGjyPRRW
— Annals of Int Med (@AnnalsofIM) November 25, 2021
M-A: Intravenous diltiazem vs. metoprolol for atrial fibrillation with rapid ventricular rate.
10 Dec, 2021 | 10:05h | UTCIntravenous diltiazem versus metoprolol for atrial fibrillation with rapid ventricular rate: A meta-analysis – The American Journal of Emergency Medicine (link to abstract – $ for full-text)
Non-inferiority randomized trial showed radiotherapy can be safely omitted in many children and adolescents with intermediate-stage and advanced-stage classical Hodgkin lymphoma.
10 Dec, 2021 | 10:04h | UTC
Life expectancy after surgical aortic valve replacement.
10 Dec, 2021 | 10:06h | UTC
Systematic Review: Antibiotics for adults and children with sore throats.
10 Dec, 2021 | 10:02h | UTCSummary: Antibiotics for adults and children with sore throats – Cochrane Library
Original Research: Antibiotics for treatment of sore throat in children and adults – Cochrane Library
Global strategy for the diagnosis and management of acute kidney injury in patients with liver cirrhosis.
10 Dec, 2021 | 09:58h | UTC
Large observational study in Israel showed a third dose (booster) of the Pfizer–BioNTech vaccine had 90% effectiveness at preventing death due to Covid-19 compared to a two-dose regimen.
9 Dec, 2021 | 10:35h | UTCBNT162b2 Vaccine Booster and Mortality Due to Covid-19 – New England Journal of Medicine
Editorial: Booster Doses and Prioritizing Lives Saved
Review: Neuropsychiatric assessment and management of the ICU survivor.
10 Dec, 2021 | 10:01h | UTC
[Press release – not published yet] Lab study suggests a third dose (booster) of the Pfizer–BioNTech vaccine may be necessary to provide an adequate immune response to the Omicron variant.
9 Dec, 2021 | 10:29h | UTCPress release: Pfizer and Biontech provide update on Omicron variant
Commentaries:
Omicron likely to weaken COVID vaccine protection – Nature
Pfizer-BioNTech says COVID booster should protect against Omicron – CIDRAP
Covid: Pfizer says booster shot promising against Omicron – BBC
Large observational study in Israel showed a third dose (booster) of the Pfizer–BioNTech vaccine reduced the rates of confirmed Covid-19 and severe illness compared to a two-dose regimen.
9 Dec, 2021 | 10:32h | UTCProtection against Covid-19 by BNT162b2 Booster across Age Groups – New England Journal of Medicine
Editorial: Booster Doses and Prioritizing Lives Saved
As 57 countries report Omicron cases, Pfizer says its boosters offer protection – but WHO cautions more research is needed.
9 Dec, 2021 | 10:28h | UTCSee also: Covid: Vaccines should work against Omicron variant, WHO says – BBC
Multiple early studies find notable Omicron vaccine evasion.
9 Dec, 2021 | 10:26h | UTCMultiple early studies find notable Omicron vaccine evasion – CIDRAP
Related: A first, small study suggests Omicron is a larger threat to Covid-19 immunity than other variants.
RCT: Among children between the ages of 6 and 11 years with uncontrolled moderate-to-severe asthma, add-on Dupilumab reduced exacerbations and improved lung function.
9 Dec, 2021 | 10:21h | UTCDupilumab in Children with Uncontrolled Moderate-to-Severe Asthma – New England Journal of Medicine
RCT: In critically ill adults undergoing tracheal intubation, use of a bougie did not significantly increase the incidence of successful first attempt intubation vs. with use of an endotracheal tube with stylet.
9 Dec, 2021 | 10:22h | UTCEffect of Use of a Bougie vs Endotracheal Tube With Stylet on Successful Intubation on the First Attempt Among Critically Ill Patients Undergoing Tracheal Intubation: A Randomized Clinical Trial – JAMA (free for a limited period)
Related: Randomized Trial: Comparison of Intubation Techniques in Patients with Difficult Airways
Opinion: Why are we still isolating vaccinated people for 10 days?
9 Dec, 2021 | 10:24h | UTCWhy Are We Still Isolating Vaccinated People for 10 Days? – The Atlantic