All Posts | Links Medicus - Free Medical News & Perspective

[Preprint] Reduced neutralization of SARS-COV-2 variant Omicron by post-immunization serum.

14 Dec, 2021 | 09:45h | UTC

[Preprint] Reduced neutralisation of SARS-COV-2 Omicron-B.1.1.529 variant by post-immunisation serum – medRxiv

News release: Vaccines shown to induce lower levels of neutralising antibodies against Omicron coronavirus variant – University of Oxford

WHO Reports | More than half a billion people pushed or pushed further into extreme poverty due to health care costs.

14 Dec, 2021 | 08:55h | UTC

News release: More than half a billion people pushed or pushed further into extreme poverty due to health care costs – World Health Organization

Report 1: Tracking Universal Health Coverage: 2021 Global monitoring report – World Health Organization

Report 2: Global monitoring report on financial protection in health 2021 – World Health Organization

Consensus Recommendations: Non-invasive imaging in coronary syndromes.

14 Dec, 2021 | 08:51h | UTC

Non-invasive imaging in coronary syndromes: recommendations of the European Association of Cardiovascular Imaging and the American Society of Echocardiography, in collaboration with the American Society of Nuclear Cardiology, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance – European Heart Journal – Cardiovascular Imaging

WHO Report | Saving lives, spending less: the case for investing in noncommunicable diseases.

14 Dec, 2021 | 08:53h | UTC

Report: Saving lives, spending less: the case for investing in noncommunicable diseases – World Health Organization

News Release: Investing 1 dollar per person per year could save 7 million lives in low and lower-middle income countries – World Health Organization

Commentary on Twitter

🆕 WHO report shows that investing only 1⃣ USD per person per year in the prevention and control of noncommunicable diseases could save almost 7⃣ million lives 🌍 by 2030. Let's #BeatNCDs!https://t.co/KP71n5M1cY pic.twitter.com/kviaoWc2J5

— World Health Organization (WHO) (@WHO) December 13, 2021

[Preprint] COVID vaccines cut the risk of transmitting Delta — but not for long

14 Dec, 2021 | 09:42h | UTC

COVID vaccines cut the risk of transmitting Delta — but not for long – Nature

Original Study [preprint]: The impact of SARS-CoV-2 vaccination on Alpha & Delta variant transmission – medRxiv

Review: Immunotherapies for hepatocellular carcinoma.

14 Dec, 2021 | 08:47h | UTC

Immunotherapies for hepatocellular carcinoma – Nature Reviews Clinical Oncology (free for a limited period – if the link is paywalled, try this one)

Review | Anti-obesity drug discovery: advances and challenges.

14 Dec, 2021 | 08:49h | UTC

Anti-obesity drug discovery: advances and challenges – Nature Reviews Drug Discovery (free for a limited period – if the link is paywalled, try this one)

Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions.

14 Dec, 2021 | 08:44h | UTC

News release: Cannabis use could cause harmful drug interactions – Washington State University

Original Study: Cannabinoid Metabolites as Inhibitors of Major Hepatic CYP450 Enzymes, with Implications for Cannabis-Drug Interactions – Drug Metabolism and Disposition

Retrospective study: antimicrobial susceptibility profiles among neonatal early-onset sepsis (EOS) pathogens – “The vast majority of contemporary EOS pathogens are susceptible to the combination of ampicillin and gentamicin”.

14 Dec, 2021 | 08:46h | UTC

Antimicrobial Susceptibility Profiles Among Neonatal Early-onset Sepsis Pathogens – The Pediatric Infectious Disease Journal

Commentary on Twitter

Are bacteria responsible for early-onset sepsis susceptible to empiric antibiotic therapy used in NICU?

A new @NICHD_NIH study by @dus10flan published in @PIDJournal #neoEBM #EBNEOAlerts https://t.co/6HJf4ZgAGa pic.twitter.com/pGMfbj3DQ6

— Evidence-Based Neo (@EBNEO) December 13, 2021

Short Review: Lymphogranuloma venereum.

14 Dec, 2021 | 08:42h | UTC

Lymphogranuloma venereum – Canadian Medical Association Journal

Podcast: No tension about inpatient hypertension.

14 Dec, 2021 | 08:39h | UTC

#310 No Tension About Inpatient Hypertension with Dr. Noble Maleque – The Curbsiders

An observational study showed Moderna is associated with increased effectiveness vs. Pfizer vaccine against symptomatic SARS-CoV-2 infection.

13 Dec, 2021 | 09:52h | UTC

Comparative effectiveness of mRNA-1273 and BNT162b2 against symptomatic SARS-CoV-2 infection – Med

Opinion | Is Moderna really better than Pfizer—or is it just a higher dose?

CDC Report: Moderna’s vaccine associated with greater effectiveness (93%) against Covid-19 hospitalization compared to Pfizer (88%) and J&J (71%) vaccines.

Commentary on Twitter

New @MedCellPress
Comparative effectiveness of the Pfizer and Moderna vaccines over time, in both the Alpha and Delta US waves, vs symptomatic infections https://t.co/RlWUXeZ2f2
consistent 8-12 % points advantage for Moderna pic.twitter.com/IwHXFIKaEp

— Eric Topol (@EricTopol) December 11, 2021

Perspective: Alcohol-related harm is a public health issue, not a lifestyle choice.

14 Dec, 2021 | 08:41h | UTC

COVID-19 pandemic and alcohol consumption: Impacts and interconnections – Toxicology Reports

National, Regional, and Global Burdens of Disease Attributable to Alcohol Use

Study: Alcohol Use and Burden for 195 Countries and Territories

Study: The Global Burden of Disease Attributable to Alcohol and Drug Use

Study: Global Alcohol Exposure Between 1990 and 2017 and Forecasts Until 2030

Analysis: Prioritizing Action on Alcohol for Health and Development

Global burden of cancer attributable to alcohol consumption – “Globally, an estimated 741.300, or 4·1% of all new cases of cancer in 2020 were attributable to alcohol consumption”.

Research: Contribution of alcohol use disorders to the burden of dementia

UK Report on SARS-CoV-2 variants of concern finds significantly lower vaccine effectiveness (VE) against Omicron infection, but a moderate to high VE of 70 to 75% is seen after a third (booster) dose.

13 Dec, 2021 | 09:53h | UTC

Report: SARS-CoV-2 variants of concern and variants under investigation in England – UK Health Security Agency

Commentaries:

Omicron: Three vaccine doses key for protection against variant – BBC

Two jabs offer little protection against Omicron infection, UK data shows – The Guardian

UK Says Omicron to Become Its Dominant Variant Within Days – Associated Press

How to recognize and manage COVID-19-associated coagulopathy.

13 Dec, 2021 | 09:45h | UTC

How to recognize and manage COVID-19-associated coagulopathy – Hematology, ASH Education Program

Covid-19: Do vaccines work against omicron—and other questions answered.

13 Dec, 2021 | 09:49h | UTC

Covid-19: Do vaccines work against omicron—and other questions answered – The BMJ

COVID-19 and thrombosis: searching for evidence.

13 Dec, 2021 | 09:47h | UTC

COVID-19 and thrombosis: searching for evidence – Hematology, ASH Education Program

Fauci says Omicron-specific version of Covid-19 vaccines may not be necessary.

13 Dec, 2021 | 09:51h | UTC

Fauci says Omicron-specific version of Covid-19 vaccines may not be necessary – STAT

NICE Guideline | Ectopic pregnancy and miscarriage: diagnosis and initial management.

13 Dec, 2021 | 09:42h | UTC

Ectopic pregnancy and miscarriage: diagnosis and initial management – National Institute for Health and Care Excellence

Opinion: Revoke the Omicron travel ban against African countries.

13 Dec, 2021 | 09:48h | UTC

Revoke the Omicron Travel Ban Against African Countries – The New York Times (a few articles per month are free)

Commentary on Twitter

Revoke the Omicron Travel Ban Against African Countries https://t.co/RhuHtnCYgR. Well said @SaadOmer3 this is not based in science and simply unjustifiable and needs to end now.

— Carlos del Rio (@CarlosdelRio7) December 11, 2021

NICE Guideline | Pelvic floor dysfunction: prevention and non-surgical management.

13 Dec, 2021 | 09:43h | UTC

Pelvic floor dysfunction: prevention and non-surgical management – National Institute for Health and Care Excellence

NICE Guideline | Inducing labor.

13 Dec, 2021 | 08:55h | UTC

Inducing labour – National Institute for Health and Care Excellence

Colorectal cancer incidence, mortality, tumor characteristics, and treatment before and after the introduction of the fecal immunochemical testing-based screening program in the Netherlands: a population-based study.

13 Dec, 2021 | 08:50h | UTC

Colorectal cancer incidence, mortality, tumour characteristics, and treatment before and after introduction of the faecal immunochemical testing-based screening programme in the Netherlands: a population-based study – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary on Twitter

New research – Breekveldt et al – #Colorectalcancer incidence, mortality, tumour characteristics, and treatment before and after introduction of the FIT-based #screening programme in the #Netherlands: a population-based studyhttps://t.co/nW9SVAhRxE #GITwitter #crcsm pic.twitter.com/GGRF9Az0tg

— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) November 23, 2021

Pooled analysis of randomized trials on the effect of empagliflozin in patients with heart failure across the spectrum of left ventricular ejection fraction (EF) showed the effects were clinically meaningful and similar in patients with EF below 65% but were attenuated in patients with EF above 65%.

13 Dec, 2021 | 08:53h | UTC

Effect of empagliflozin in patients with heart failure across the spectrum of left ventricular ejection fraction – European Heart Journal

Commentary on Twitter

Effect of empagliflozin on heart failure hospitalizations: news from the pooled analysis on both the EMPEROR-Reduced and EMPEROR-Preserved trials! #empaglifozin #heart #failure #hospitalization #ehj #cardiotwitter @escardio @ESC_Journals https://t.co/W6FuYbwVzx pic.twitter.com/5qLXDVaC89

— EHJ Editor-in-Chief (@ehj_ed) December 11, 2021