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Estimating global, regional, and national daily and cumulative infections with SARS-CoV-2 through Nov 14, 2021: a statistical analysis.

11 Apr, 2022 | 01:58h | UTC

Estimating global, regional, and national daily and cumulative infections with SARS-CoV-2 through Nov 14, 2021: a statistical analysis – The Lancet

Invited Commentary: How to interpret the total number of SARS-CoV-2 infections – The Lancet

 

Commentary on Twitter (thread – click for more)

 

Review: Gastrointestinal post-acute COVID-19 syndrome.

11 Apr, 2022 | 01:49h | UTC

Gastrointestinal post-acute COVID-19 syndrome – Nature Reviews Gastroenterology & Hepatology

 

Commentary on Twitter

 

RCT: Effect of Gram Stain–Guided initial antibiotic therapy on clinical response in patients with ventilator-associated pneumonia.

11 Apr, 2022 | 01:36h | UTC

Effect of Gram Stain–Guided Initial Antibiotic Therapy on Clinical Response in Patients With Ventilator-Associated Pneumonia: The GRACE-VAP Randomized Clinical Trial – JAMA Network Open

Commentary: Can Gram Stains Guide Antibiotics for Pneumonia in Critical Care? – Medscape (free registration required)

 

Commentary on Twitter

 

CoronaVac vaccine is effective in preventing symptomatic and severe COVID-19 in pregnant women in Brazil: a test-negative case-control study.

11 Apr, 2022 | 01:40h | UTC

CoronaVac vaccine is effective in preventing symptomatic and severe COVID-19 in pregnant women in Brazil: a test-negative case-control study – BMC Medicine

 

Clinical care of severe acute respiratory infections – Tool kit (COVID-19 adaptation, update 2022).

11 Apr, 2022 | 01:45h | UTC

Clinical care of severe acute respiratory infections – Tool kit – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

UK clinical guideline for the prevention and treatment of osteoporosis.

11 Apr, 2022 | 01:33h | UTC

UK clinical guideline for the prevention and treatment of osteoporosis – Archives of Osteoporosis

 

Guideline Synopsis: Management of chronic multisymptom illness.

11 Apr, 2022 | 01:29h | UTC

Management of Chronic Multisymptom Illness: Synopsis of the 2021 US Department of Veterans Affairs and US Department of Defense Clinical Practice Guideline – Mayo Clinic Proceedings

 

NCCN Guidelines: CAR T-cell–related toxicities in patients with cancer.

11 Apr, 2022 | 01:32h | UTC

Management of Immunotherapy-Related Toxicities, Version 1.2022, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network

Related:

Reviews: CAR T-Cell Therapy Toxicities and Side Effects

Reviews: CAR T-Cell Therapy Toxicities and Side Effects

Critical Care Management of Chimeric Antigen Receptor T Cell–related Toxicity. Be Aware and Prepared

Reviews: CAR T-Cell Therapy Toxicities and Side Effects

 

AHA Scientific Statement: addressing social determinants of health and mitigating health disparities across the lifespan in congenital heart disease.

11 Apr, 2022 | 01:31h | UTC

Addressing Social Determinants of Health and Mitigating Health Disparities Across the Lifespan in Congenital Heart Disease: A Scientific Statement From the American Heart Association – Circulation

Commentary: Social determinants of health affect care for people with congenital heart disease – American Heart Association

 

Predicting avoidable health care utilization: practical considerations for artificial intelligence/machine learning models in population health.

11 Apr, 2022 | 01:27h | UTC

Predicting Avoidable Health Care Utilization: Practical Considerations for Artificial Intelligence/Machine Learning Models in Population Health – Mayo Clinic Proceedings

 

RCT: Effects of abiraterone plus prednisone added to androgen deprivation therapy and docetaxel in de novo metastatic castration-sensitive prostate cancer.

11 Apr, 2022 | 01:23h | UTC

Abiraterone plus prednisone added to androgen deprivation therapy and docetaxel in de novo metastatic castration-sensitive prostate cancer (PEACE-1): a multicentre, open-label, randomised, phase 3 study with a 2 × 2 factorial design – The Lancet (link to abstract – $ for full-text)

 

RCT: Efficacy and safety of gefapixant, a P2X3 receptor antagonist, in refractory chronic cough and unexplained chronic cough.

11 Apr, 2022 | 01:22h | UTC

Efficacy and safety of gefapixant, a P2X3 receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Large database with 10 registries or clinical trials finds valve-in-valve transcatheter aortic valve implantation (TAVI) resulted in similar mortality and stroke rates compared to native valve TAVI.

11 Apr, 2022 | 01:02h | UTC

Outcomes in Valve-in-Valve Transcatheter Aortic Valve Implantation – American Journal of Cardiology

 

M-A: Oxygen targets during mechanical ventilation in the ICU.

11 Apr, 2022 | 01:26h | UTC

Oxygen Targets During Mechanical Ventilation in the ICU: A Systematic Review and Meta-Analysis – Critical Care Explorations

 

M-A: Association of olfactory impairment with all-cause mortality.

11 Apr, 2022 | 01:01h | UTC

Association of Olfactory Impairment With All-Cause Mortality: A Systematic Review and Meta-analysis – JAMA Otolaryngology-Head & Neck Surgery (free for a limited period)

Invited Commentary: Olfactory Impairment and Mortality—Is Smell Loss Deadly? – JAMA Otolaryngology-Head & Neck Surgery (free for a limited period)

 

Commentary on Twitter

 

Perspective: Supervised consumption sites—a tool for reducing risk of overdose deaths and infectious diseases in people who use illicit drugs.

11 Apr, 2022 | 00:59h | UTC

Supervised Consumption Sites—A Tool for Reducing Risk of Overdose Deaths and Infectious Diseases in People Who Use Illicit Drugs – JAMA (free for a limited period)

 

Commentary on Twitter

 

M-A: Prophylactic therapies for morbidity and mortality after aneurysmal subarachnoid hemorrhage.

11 Apr, 2022 | 00:52h | UTC

Prophylactic Therapies for Morbidity and Mortality After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Network Meta-Analysis of Randomized Trials – Stroke (link to abstract – $ for full-text)

Related: RCT: Effects of clazosentan on cerebral vasospasm–related morbidity and all-cause mortality after aneurysmal subarachnoid hemorrhage.

 

Commentary on Twitter

 

You must be joking: funny paper titles might lead to more citations.

11 Apr, 2022 | 00:51h | UTC

You must be joking: funny paper titles might lead to more citations – Nature

Original Study (preprint): If this title is funny, will you cite me? Citation impacts of humor and other features of article titles in ecology and evolution – bioRxiv

 

M-A: Sentinel lymph node biopsy in patients with ductal carcinoma in situ.

11 Apr, 2022 | 00:46h | UTC

Sentinel lymph node biopsy in patients with ductal carcinoma in situ: systematic review and meta-analysis – BJS Open

 

Commentary on Twitter

 

Effects of aspirin on dementia and cognitive function in diabetic patients: the ASCEND trial.

11 Apr, 2022 | 00:50h | UTC

Effects of aspirin on dementia and cognitive function in diabetic patients: the ASCEND trial – European Heart Journal

Original Study: Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes

 

Commentary on Twitter (images under a https://creativecommons.org/licenses/by/4.0/ license)

 

M-A: Prehospital risk assessment in patients suspected of non-ST-segment elevation acute coronary syndrome.

11 Apr, 2022 | 00:48h | UTC

Prehospital risk assessment in patients suspected of non-ST-segment elevation acute coronary syndrome: a systematic review and meta-analysis – BMJ Open

 

Commentary on Twitter

 

M-A: Enhanced recovery care vs. traditional care in laparoscopic hepatectomy.

11 Apr, 2022 | 00:43h | UTC

Enhanced Recovery Care vs. Traditional Care in Laparoscopic Hepatectomy: A Systematic Review and Meta-Analysis – Frontiers in Surgery

Related:

Guidelines for Perioperative Care for Liver Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations – World Journal of Surgery

Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines (some guidelines are free)

 

M-A: Effect of obesity treatment interventions in preschool children aged 2–6 years.

11 Apr, 2022 | 00:47h | UTC

Effect of obesity treatment interventions in preschool children aged 2–6 years: a systematic review and meta-analysis – BMJ Open

 

Internal mammary node irradiation in patients with node-positive early breast cancer: fifteen-year results from the Danish breast cancer group internal mammary node study.

11 Apr, 2022 | 00:41h | UTC

Internal Mammary Node Irradiation in Patients With Node-Positive Early Breast Cancer: Fifteen-Year Results From the Danish Breast Cancer Group Internal Mammary Node Study – Journal of Clinical Oncology (link to abstract – $ for full-text)

 

Commentary from the author on Twitter (thread – click for more)

 

RCT: In critically ill children requiring noninvasive respiratory support following extubation, high-flow nasal cannula therapy was NOT noninferior to CPAP, resulting in increased time to liberation from respiratory support.

8 Apr, 2022 | 11:07h | UTC

Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Selecting Intermediate Respiratory Support Following Extubation in the Pediatric Intensive Care Unit – JAMA (free for a limited period)

News Release: Trial identifies most effective breathing support for children in intensive care – Imperial College London

 

Commentary on Twitter

 

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