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M-A: Interventions to reduce opioid prescriptions following urological surgery.

11 Apr, 2022 | 00:42h | UTC

Interventions to Reduce Opioid Prescriptions following Urological Surgery: A Systematic Review and Meta-Analysis – The Journal of Urology

 

Cohort Study: Use of Phosphodiesterase 5 Inhibitors linked to increased risk of ocular adverse events.

8 Apr, 2022 | 11:04h | UTC

Risk of Ocular Adverse Events Associated With Use of Phosphodiesterase 5 Inhibitors in Men in the US – JAMA Ophthalmology (free for a limited period)

News Release: U.S. insurance claims show strong link between ED medications and vision problems – University of British Columbia

Commentaries:

Phase 4 Studies on Phosphodiesterase 5 Inhibitors – JAMA Ophthalmology (free for a limited period)

Expert reaction to study looking at risk of vision impairment and loss, and use of phosphodiesterase type 5 inhibitors – Science Media Centre

Could Viagra, Cialis Raise Men’s Odds for Eye Trouble? – HealthDay

 

State of the Art Review: Prognostication and shared decision making in neurocritical care.

8 Apr, 2022 | 10:53h | UTC

Prognostication and shared decision making in neurocritical care – The BMJ

 

Commentary on Twitter

 

Risk factors and prognostic implications of diagnosis of cancer within 30 days after an emergency hospital admission (emergency presentation).

8 Apr, 2022 | 10:52h | UTC

Risk factors and prognostic implications of diagnosis of cancer within 30 days after an emergency hospital admission (emergency presentation): an International Cancer Benchmarking Partnership (ICBP) population-based study – The Lancet Oncology

Commentary: Emergency presentations: what are they, and what do they mean for cancer survival? – Cancer Research UK

 

Commentary on Twitter (thread – click for more) – text and images under a Creative Commons Attribution (CC BY 4.0) licence

 

Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.

8 Apr, 2022 | 10:58h | UTC

Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 – The Lancet Gastroenterology & Hepatology

Invited Commentary: Global epidemiology and prevention of colorectal cancer – The Lancet Gastroenterology & Hepatology (free registration required)

 

Opinion | Why the WHO took two years to say COVID is airborne.

8 Apr, 2022 | 10:38h | UTC

Why the WHO took two years to say COVID is airborne – Nature

 

M-A: Thrombosis patterns and clinical outcome of COVID-19 vaccine-induced immune thrombotic thrombocytopenia.

8 Apr, 2022 | 10:50h | UTC

Thrombosis patterns and clinical outcome of COVID-19 vaccine-induced immune thrombotic thrombocytopenia: A Systematic Review and Meta-Analysis – International Journal of Infectious Diseases

Related:

Case series of Thrombosis with Thrombocytopenia Syndrome after Covid-19 vaccination in the US.

Review: Vaccine-induced immune thrombotic thrombocytopenia.

Vaccine induced immune thrombocytopenia and thrombosis: summary of NICE guidance.

Clinical features of vaccine-induced immune thrombocytopenia and thrombosis.

Review: Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis.

Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.

Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2.3 per million vaccinees. (several articles and resources on the subject)

 

Long COVID in children: a modified Delphi process.

8 Apr, 2022 | 10:40h | UTC

Long COVID (post-COVID-19 condition) in children: a modified Delphi process – Archives of Disease in Childhood

Related:

First research definition for ‘Long COVID’ in kids and young people formally agreed.

Cohort Study: Physical and mental health 3 months after SARS-CoV-2 infection (long COVID) among adolescents in England.

A nationwide cohort study in Denmark showed Long Covid in children is rare and mainly of short duration.

Editorial | Long covid in children and adolescents – “Risk appears low, but many questions remain”.

M-A: Persistent symptoms following SARS-CoV-2 infection among children and young people – “Higher study quality was associated with lower prevalence of all symptoms, except loss of smell and cognitive symptoms”.

Review: Long COVID symptoms in children rarely persist beyond three months.

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

 

M-A: Diagnostic performance of CO-RADS for Covid-19.

8 Apr, 2022 | 10:31h | UTC

Diagnostic performance of CO-RADS for COVID-19: a systematic review and meta-analysis – European Radiology

Related: CO-RADS – A categorical CT assessment scheme for patients with suspected COVID-19: definition and evaluation – Radiology

 

Review | Chronic pain and infection: mechanisms, causes, conditions, treatments, and controversies.

8 Apr, 2022 | 10:27h | UTC

Chronic pain and infection: mechanisms, causes, conditions, treatments, and controversies – BMJ Medicine

 

Putting positive experiences at the center of postnatal care.

8 Apr, 2022 | 10:34h | UTC

Putting positive experiences at the centre of postnatal care – Evidently Cochrane Blog

Original Guideline: WHO recommendations on maternal and newborn care for a positive postnatal experience.

 

Antiepileptic drug monotherapy for epilepsy: a network meta‐analysis of individual participant data.

8 Apr, 2022 | 10:20h | UTC

Antiepileptic drug monotherapy for epilepsy: a network meta‐analysis of individual participant data – Cochrane Library

Summary: Antiepileptic drug monotherapy (single drug treatment) for epilepsy – Cochrane Library

 

Stroke: advances in treatment offer hope for patients.

8 Apr, 2022 | 10:23h | UTC

Stroke: advances in treatment offer hope for patients – Evidently Cochrane

 

Review: Epigenetics in congenital heart disease.

8 Apr, 2022 | 10:12h | UTC

Epigenetics in Congenital Heart Disease – Journal of the American Heart Association

 

M-A: Mechanical thrombectomy with retrievable stents and aspiration catheters for acute ischemic stroke.

8 Apr, 2022 | 10:21h | UTC

Mechanical thrombectomy with retrievable stents and aspiration catheters for acute ischaemic stroke: a meta-analysis of randomised controlled trials – EuroIntervention (link to abstract – $ for full-text)

Commentary: Mechanical Stroke Thrombectomy May Reduce Death: Meta-analysis – TCTMD

 

Commentary on Twitter

 

Interventions for treating catheter‐related bloodstream infections in people receiving maintenance hemodialysis.

8 Apr, 2022 | 10:18h | UTC

Interventions for treating catheter‐related bloodstream infections in people receiving maintenance haemodialysis – Cochrane Library

Summary: Interventions for treating catheter-related bloodstream infections in people receiving maintenance haemodialysis – Cochrane Library

 

Study Commentary | Immediate versus delayed cardiac catheterization in post-arrest patients without ST elevation myocardial infarction: is survivorship bias an important influence?

8 Apr, 2022 | 10:11h | UTC

Immediate Versus Delayed Cardiac Catheterization in Post-Arrest Patients Without ST Elevation Myocardial Infarction: Is Survivorship Bias an Important Influence? – Annals of Emergency Medicine

Original Study: #ESCCongress – RCT: Immediate coronary angiography after out-of-hospital cardiac arrest without ST-segment elevation did not improve outcomes compared to delayed/selective angiography.

 

Study Commentary | Back to BaSICS (study that compared balanced solution vs. 0.9% saline solution in critically ill patients).

8 Apr, 2022 | 10:09h | UTC

Back to BaSICS – Annals of Emergency Medicine

Original Studies:

BaSICS RCT: Among critically ill patients requiring fluid therapy, treatment with a balanced solution did not lead to reduced mortality compared to a 0.9% saline solution.

BaSICS RCT: Among critically ill patients requiring fluid therapy, there was no difference in mortality with slower (333 mL/h) vs. faster (999 mL/h) intravenous fluid bolus rates.

Related:

Perspective: The ongoing saga of normal saline vs. balanced fluids.

RCT: In critically ill adults, using a balanced multielectrolyte solution did not lower the risk of death or acute kidney injury compared to standard saline.

Balanced Crystalloids versus Saline in Critically Ill Adults — A Systematic Review with Meta-Analysis – NEJM Evidence

Cochrane Review: Buffered Solutions Do Not Improve Mortality in Critically Ill Adults and Children Compared to 0,9% Saline

 

Study Commentary | To Bougie or not to Bougie: Bougie vs. Stylet for first-pass intubation success.

8 Apr, 2022 | 10:07h | UTC

To Bougie or Not to Bougie: Bougie versus Stylet for First-Pass Intubation Success – Annals of Emergency Medicine

Original Study: RCT: In critically ill adults undergoing tracheal intubation, use of a bougie did not significantly increase the incidence of successful first attempt intubation vs. with use of an endotracheal tube with stylet.

 

Translating research into practice: What’s new in the 2021 EAACI food allergy prevention guidelines?

8 Apr, 2022 | 10:00h | UTC

Translating research into practice: What’s new in the 2021 EAACI food allergy prevention guidelines? – Clinical & Experimental Allergy

Original Guideline: EAACI guideline: Preventing the development of food allergy in infants and young children – Pediatric Allergy and Immunology

Related:

Practice Guideline: Prevention and management of allergic reactions to food in child care centers and schools

Study: Early Introduction of Allergenic Foods Can Prevent Food Allergies in High Risk Infants

AAP Updated Recommendations for Dietary Interventions to Prevent Atopic Disease

Timing of introduction of allergenic solids for infants at high risk – Canadian Paediatric Society (free)

Short Review: Food Allergy Prevention with Early Food Introduction

 

Study Commentary | Advanced glaucoma: surgery lowers pressure in the eye more effectively than eye drops.

8 Apr, 2022 | 10:06h | UTC

Advanced glaucoma: surgery lowers pressure in the eye more effectively than eye drops – National Institute for Health Research

Original Study: Pragmatic RCT: Among patients with advanced glaucoma, primary trabeculectomy resulted in similar quality of life and safety outcomes and achieved a lower intraocular pressure compared with primary medication.

 

Autistic people are six times more likely to attempt suicide – poor mental health support may be to blame.

8 Apr, 2022 | 10:02h | UTC

Autistic people are six times more likely to attempt suicide – poor mental health support may be to blame – The Conversation

 

Current applications and limitations of European guidelines on blood pressure measurement: implications for clinical practice.

8 Apr, 2022 | 09:56h | UTC

Current applications and limitations of European guidelines on blood pressure measurement: implications for clinical practice – Internal and Emergency Medicine

Related:

Randomized Diagnostic Study: home blood pressure measurements correlate better with 24-h ambulatory monitoring measurements compared to clinic, and kiosk measurements.

Practice guidelines for office and out-of-office blood pressure measurement.

Study suggests a 30-second interval between automated office blood pressure measurements is as accurate and reliable as a 60-second interval.

USPSTF Statement recommends screening for hypertension in adults 18 years or older with office blood pressure measurement – diagnostic confirmation with blood pressure measurements outside of the clinical setting is advised before starting treatment

Study suggests that 7 days of home blood pressure monitoring is likely better than 24h ambulatory monitoring or 3 office measurements

 

Brief Review: How to do lung ultrasound.

8 Apr, 2022 | 09:52h | UTC

How to do lung ultrasound – European Heart Journal – Cardiovascular Imaging

 

Systematic Review: How the reduction of working hours could influence health outcomes.

8 Apr, 2022 | 09:50h | UTC

How the reduction of working hours could influence health outcomes: a systematic review of published studies – BMJ Open

 

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