All Posts
Guidance to best tools and practices for systematic reviews
14 Jun, 2023 | 14:12h | UTCGuidance to best tools and practices for systematic reviews – Systematic Reviews
M-A | Oseltamivir fails to lower hospitalization risk in adult and adolescent influenza patients
13 Jun, 2023 | 14:12h | UTC
Commentary on Twitter
In this systematic review and meta-analysis of 15 RCTs, oseltamivir was not associated with reduced risk of first hospitalization compared with placebo or standard of care among influenza-infected adult and adolescent outpatients. https://t.co/UEqsbA2JQZ
— JAMA Internal Medicine (@JAMAInternalMed) June 12, 2023
Viewpoint | Detecting selection bias in observational studies—when interventions work too fast
13 Jun, 2023 | 14:09h | UTCDetecting Selection Bias in Observational Studies—When Interventions Work Too Fast – JAMA Internal Medicine (free for a limited period)
Commentary from the author on Twitter
Our paper in @JAMAInternalMed helps recognize confounding/biases in obs studies.https://t.co/qhptGVAIev
Look at image on left-a randomized study in which K better than V (slow separation of curves, plausible).
On right-retrospective obs study of VRD vs KRd.Early separation!! pic.twitter.com/mma9vGpueQ
— Manni Mohyuddin (@ManniMD1) June 12, 2023
Review | Wastewater monitoring can anchor global disease surveillance systems
13 Jun, 2023 | 14:07h | UTCWastewater monitoring can anchor global disease surveillance systems – The Lancet Global Health
Related:
Use of Wastewater for Mpox Outbreak Surveillance in California – New England Journal of Medicine
Opinion: Wastewater analysis can be a powerful public health tool—if it’s done sensibly.
CDC unveils its latest weapon in Covid-19 detection: wastewater.
[Preprint] Wastewater genomic testing can effectively track COVID-19 variants of concern.
Human Waste Could Be The Next Big Weapon in Controlling COVID-19 – TIME
Next steps for wastewater testing to help end this pandemic — and prevent the next one – STAT
The myriad ways sewage surveillance is helping fight COVID around the world – Nature
It’s time to begin a national wastewater testing program for Covid-19 – STAT
Coronavirus: Testing sewage an ‘easy win’ – BBC
Saving time and money in biomedical publishing: the case for free-format submissions with minimal requirements
13 Jun, 2023 | 14:08h | UTCCommentary: Revealed: the millions of dollars in time wasted making papers fit journal guidelines – Nature
Review | Diagnosis and management of depression in adolescents
13 Jun, 2023 | 14:05h | UTCDiagnosis and management of depression in adolescents – Canadian Medical Association Journal
News Release: How to diagnose and manage depression in adolescents: A new review for clinicians – Canadian Medical Association Journal
AHA Scientific Statement | Contaminant metals as cardiovascular risk factors
13 Jun, 2023 | 14:04h | UTCNews Release: Chronic exposure to lead, cadmium and arsenic increases risk of cardiovascular disease – American Heart Association
Top Things to Know: Contaminant Metals as CV Risk Factors – American Heart Association
Commentary: Toxic Metals: The Poisons that are “Killing Us Softly” – American Heart Association
Commentary on Twitter
⚠️ Chronic exposure to lead, cadmium & arsenic ⬆️ risk of CVD
Monitoring exposure in ?, ?& ?is important for reducing inequity in CVD risk, according to a new AHA scientific statement published in @JAHA_AHA
✍️ @GLamasMD @anavasachttps://t.co/v5TOvvettD pic.twitter.com/36iCmfDmDP
— AHA Science (@AHAScience) June 12, 2023
Consensus Statement | Three-dimensional transesophageal echocardiography
13 Jun, 2023 | 14:02h | UTC
RCT | No change in delayed graft function with normothermic perfusion vs. cold storage in kidney transplants
13 Jun, 2023 | 14:00h | UTC
Commentary on Twitter
In an open-label, randomized controlled trial, normothermic machine perfusion of kidneys from donation after circulatory death was found to be feasible and safe but did not reduce the rate of delayed graft function compared to static cold storage. https://t.co/faaAzK3bpc pic.twitter.com/iL7Je7Z7jO
— Nature Medicine (@NatureMedicine) June 2, 2023
Review | The cervical spine in tension type headache
13 Jun, 2023 | 13:58h | UTCThe cervical spine in tension type headache – Musculoskeletal Science and Practice
Commentary on Twitter
The cervical spine in tension type headache
???https://t.co/EFcxBlDO34 pic.twitter.com/y7SyA3T7qt
— Physio Meets Science (@PhysioMeScience) June 1, 2023
Machine learning proves effective in predicting left ventricular hypertrophy through ECG analysis, study shows
13 Jun, 2023 | 13:57h | UTC
Commentary on Twitter
Predicting left ventricular hypertrophy from the 12-lead electrocardiogram in the UK Biobank imaging study using #MachineLearning https://t.co/3pnVQtkPH5 #EHJDigital #WhyCMR @BruiningNico @rafavidalperez @GerdHindricks @rbcasado pic.twitter.com/jbjuBJVIHW
— European Society of Cardiology Journals (@ESC_Journals) June 2, 2023
Review | Challenges and opportunities in antimicrobial stewardship among hematopoietic stem cell transplant and oncology patients
13 Jun, 2023 | 13:55h | UTC
Review | Screening for prostate cancer: evidence, ongoing trials, policies and knowledge gaps
13 Jun, 2023 | 13:52h | UTCScreening for prostate cancer: evidence, ongoing trials, policies and knowledge gaps – BMJ Oncology
RCT | Capivasertib–fulvestrant improves PFS vs. fulvestrant alone in HR+ advanced breast cancer
13 Jun, 2023 | 13:54h | UTCCapivasertib in Hormone Receptor–Positive Advanced Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Video: Capivasertib in Advanced Breast Cancer | NEJM
Commentary: Capivasertib-fulvestrant therapy increases PFS in HR-positive breast cancer – MedicalXpress
Commentary on Twitter
Among persons with breast cancer previously treated with hormonal therapy, the AKT pathway inhibitor capivasertib when added to fulvestrant significantly prolonged progression-free survival as compared with fulvestrant alone. Full results of CAPItello-291: https://t.co/ZCBHkG305b
— NEJM (@NEJM) May 31, 2023
Review | How to use cardiac troponin in non-cardiac surgery
13 Jun, 2023 | 13:50h | UTC
Consensus Statement | Clinical quantitative coronary artery stenosis and coronary atherosclerosis imaging
13 Jun, 2023 | 13:49h | UTCClinical quantitative coronary artery stenosis and coronary atherosclerosis imaging: a Consensus Statement from the Quantitative Cardiovascular Imaging Study Group – Nature Reviews Cardiology (if the link is paywalled, try this one)
Commentary on Twitter
Check out our new Consensus Statement by @ProfDewey and the Quantitative Cardiovascular Imaging Study Group on the optimal use of imaging modalities to detect and assess coronary artery stenosis and atherosclerosis | https://t.co/WcKzwvE3UU pic.twitter.com/bipgb1zYuE
— Nature Reviews Cardiology (@NatRevCardiol) June 8, 2023
Review | How to improve the efficiency and the safety of real-time ultrasound-guided central venous catheterization
13 Jun, 2023 | 13:47h | UTC
Consensus Statement | Use of liothyronine (T3) in hypothyroidism
13 Jun, 2023 | 13:46h | UTC
Review | Post-intensive care syndrome
13 Jun, 2023 | 13:44h | UTCPost-intensive care syndrome (PICS): recent updates – Journal of Intensive Care
M-A | Kangaroo mother care reduces mortality in preterm and low birth weight infants
13 Jun, 2023 | 13:41h | UTCNews Release: Effects of KMC in preterm and low birth weight infants – BMJ / News Medical
Related:
M-A | The efficacy of Kangaroo-Mother care to the clinical outcomes of LBW and premature infants
Kangaroo mother care to reduce morbidity and mortality in low birthweight infants – Cochrane Library
IDSA 2023 Guidance on the treatment of antimicrobial resistant gram-negative infections
12 Jun, 2023 | 13:58h | UTCRelated:
M-A | Elevated HbA1c in gestational diabetes mellitus tied to 1.7-fold rise in large for gestational age incidence
13 Jun, 2023 | 13:39h | UTC
RCT | Noninferior survival rates with hearts donated after circulatory death versus brain death
12 Jun, 2023 | 13:57h | UTCTransplantation Outcomes with Donor Hearts after Circulatory Death – New England Journal of Medicine (link to abstract – $ for full-text)
Video summary: Outcomes with Donor Hearts after Circulatory Death | NEJM
News Release: Multicenter Trial Finds Using Circulatory Death Donors is Safe and Effective for Heart Transplantation – Northwestern Medicine
Commentary: Transplantation Outcomes With Donor Hearts After Circulatory Death – American College of Cardiology
Commentary on Twitter
In a randomized trial, survival at 6 months after transplantation with hearts donated after circulatory death was noninferior to that with hearts donated after brain death. https://t.co/IymsknTqSE#cardiology pic.twitter.com/oYAS10fVJt
— NEJM (@NEJM) June 7, 2023
2ry Analysis of a RCT | Metformin linked to 41% reduction in long COVID incidence in outpatient treatment
12 Jun, 2023 | 13:55h | UTCNews Release: Study shows metformin lowers the risk of getting long COVID – University of Minnesota Medical School
Commentary on Twitter
These data not persuasive. There are 6 different arms. 3 drugs. This is not the primary endpoint. No adjustment for multiple testing.
Even USFDA would not accept these data for regulatory approval, and they are basically working for Pharma at this pthttps://t.co/FZoxo9shtG
— Vinay Prasad MD MPH (@VPrasadMDMPH) June 9, 2023
Pre-clinical Study | Taurine deficiency and aging, a correlation found in mice, monkeys, and worms
12 Jun, 2023 | 13:53h | UTCTaurine deficiency as a driver of aging – Science
Invited Commentary: Taurine linked with healthy aging – Science
News Release: Taurine May Be a Key to Longer and Healthier Life – Columbia University
Commentary on Twitter
Taurine deficiency may be a driver for aging, finds a new Science study in several animal models. The results warrant clinical trials to examine taurine’s effect on healthy lifespan in humans.
?: https://t.co/iJfI4rne7o#SciencePerspective: https://t.co/EdOKecgoqF pic.twitter.com/dekChiKRN3
— Science Magazine (@ScienceMagazine) June 8, 2023