Archives
Cohort Study: Accurately Measured Sodium Intake Showed a Linear Relationship with Mortality
29 Jun, 2018 | 02:27h | UTCErrors in estimating usual sodium intake by the Kawasaki formula alter its relationship with mortality: implications for public health – International Journal of Epidemiology (link to abstract – $ for full-text)
Commentaries: Accurate measurements of sodium intake confirm relationship with mortality – ScienceDaily (free) AND Better estimate of intake more firmly links salt, death – UPI (free)
Related Report: Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks – Agency for Healthcare Research and Quality (free)
Guideline: Advance Care Planning in Dementia
29 Jun, 2018 | 02:30h | UTCRelated: New Document for Patients: Advanced Health Directive for Dementia (free document and commentaries) AND Alzheimer’s? Your Paperwork May Not Be in Order – The New York Times (free)
Richard Lehman’s journal review – 25 June 2018
29 Jun, 2018 | 02:24h | UTCRichard Lehman’s journal review, 25 June 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Randomized Trial: Parent-Child Psychotherapy Targeting Emotion Development for Early Childhood Depression
29 Jun, 2018 | 02:19h | UTCA Randomized Controlled Trial of Parent-Child Psychotherapy Targeting Emotion Development for Early Childhood Depression – The American Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Parent-Child Psychotherapy Leads to Improvements in Young Children With Depression – Psychiatric News Alert (free) AND Psychotherapeutic intervention shows promise for treating depression in preschool-aged children – NIH News Releases (free) AND Parent-child therapy helps young children with depression – Washington University School of Medicine, via ScienceDaily (free)
Related Study: Talking therapy given by parents shows promise for childhood anxiety disorders (free research, editorial and commentaries)
Systematic Review: Saline Irrigation for Allergic Rhinitis
29 Jun, 2018 | 02:25h | UTCSaline irrigation for allergic rhinitis – Cochrane Library (free)
Summary: Nasal saline for allergic rhinitis – Cochrane Library (free)
Randomized Trial: Robot-Assisted Radical Cystectomy No Better Than Open Radical Cystectomy in Patients with Bladder Cancer
29 Jun, 2018 | 02:18h | UTCRobot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Robotic, Open Cystectomy Offer Comparable Bladder Cancer Outcomes – Renal & Urology News (free) AND RAZOR study: No differences in robotic vs open surgery for bladder cancer – Coloproctology News (free) AND Robotic surgery is no better than traditional surgery, bladder cancer study finds – The Washington Post (free)
Review: Difficult Airway Management with Proposal of a Simplified Algorithm
29 Jun, 2018 | 02:21h | UTCRelated Guidelines: Difficult Airway Society 2015 guidelines for management of unanticipated difficult intubation in adults – British Journal of Anaesthesia (free) AND Practice Guidelines for Management of the Difficult Airway: An Updated Report by the American Society of Anesthesiologists Task Force on Management of the Difficult Airway – Anesthesiology (free)
Meta-Analysis: Oxygen Saturation Targets and Death or Disability in Extremely Preterm Infants
29 Jun, 2018 | 02:15h | UTCAssociation Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration – JAMA (link to abstract – $ for full-text)
Commentaries: Oxygen for preterm infants, what dose of this toxic drug is the right dose? #NeoEBM – Neonatal Research (free) AND Lower and higher oxygen saturation targets result in equal but contrasting outcomes for extremely preterm infants – 2 Minute Medicine (free)
Review: Imaging of Abnormal Liver Function Tests
29 Jun, 2018 | 02:09h | UTCImaging of abnormal liver function tests – Clinical Liver Disease (free)
Systematic Review: Non-pharmacological Interventions to Improve Nighttime Sleep Among Residents of Long-Term Care Settings
29 Jun, 2018 | 02:10h | UTC
Cross-Sectional Study: Portable Music Players Associated with Hearing Loss in Children
29 Jun, 2018 | 02:11h | UTCAssociation Between Portable Music Player Use and Hearing Loss Among Children of School Age in the Netherlands – JAMA Otolaryngology-Head & Neck Surgery (link to abstract – $ for full-text)
Commentaries: Portable music players tied to hearing loss in kids – Reuters (free) AND Portable Music Player Use Linked to Hearing Loss in Children – MPR (free)
Review: The Venous Ulcer Continues to be a Clinical Challenge
29 Jun, 2018 | 02:08h | UTCThe venous ulcer continues to be a clinical challenge: an update – Burns & Trauma (free)
Related Cochrane Review: Dressings and topical agents for treating venous leg ulcers (free) AND Summary (free)
Commentary: Some Science Journals That Claim to Peer Review Papers Do Not Do So
29 Jun, 2018 | 02:05h | UTCSome science journals that claim to peer review papers do not do so – The Economist (a few articles per month are free)
Guideline: Management of Patients with Cervical Cancer
29 Jun, 2018 | 02:04h | UTC
Fri, June 29 – 10 Stories of The Day!
29 Jun, 2018 | 01:26h | UTC
Commentary: Reducing the need for 24-hour blood pressure monitors in general practice – University of Oxford (free)
The tool: freely available online here
Commentaries: Penicillin-allergic patients may run bigger risk of MRSA, C diff – CIDRAP (free) AND Patients believed allergic to penicillin have increased risks of MRSA and C. difficile – Massachusetts General Hospital (free) AND Patients with Documented Penicillin Allergy at Higher Risk for MRSA, C. difficile – NEJM Physician’s First Watch (free)
4 – Perspective: Potential Policy Approaches to Address Diet-Related Diseases – JAMA (free for a limited period)
Related: Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization (free) AND To improve global health, tax the things that are killing us – Financial Times (free articles, commentaries and reports) AND The Lancet taskforce on NCDs and economics (free series and commentaries)
5 – Perspective: What’s the Best Way to Treat Normal-Weight People With Metabolic Abnormalities? – JAMA (free for a limited period)
Related Guidelines: UK clinical guideline for the prevention and treatment of osteoporosis – Archives of Osteoporosis (free) AND Treatment of Low Bone Density or Osteoporosis to Prevent Fractures in Men and Women: A Clinical Practice Guideline Update from the American College of Physicians – Annals of Internal Medicine (free)
Commentaries: Frailty: from clinical syndrome to epidemiological construct? – The Lancet Public Health (free) AND Old before your time? Scientists have put together five warning signs middle-aged people will suffer from frailness in retirement – Daily Mail (free) AND Five modifiable risk factors found to help reach healthy old age – OnMedica (free)
Related Study: Impact of Healthy Lifestyle Factors on Life Expectancies (link to abstract and commentaries)
9 – Oncological outcome after MRI‐based selection for neoadjuvant chemoradiotherapy in the OCUM Rectal Cancer Trial – British Journal of Surgery (link to abstract – $ for full-text)
Commentaries: Many patients with rectal cancer may not need chemoradiotherapy – eCancer News (free) AND Limiting Chemo to High-Risk Rectal Cancer Called Feasible – MedPage Today (free registration required) AND OCUM Trial: Some Rectal Cancers Need Only Surgery – Medscape (free registration required)
10 – Study Guide: Rip Current Heroes Study Guide – National Geographic (free PDF)
News Release: Rip Current Heroes Study Guide (Free)
Videos: Rip Current Heroes (free)
Related Reports: Preventing drowning: an implementation guide – World Health Organization (free) AND Global report on drowning: preventing a leading killer – World Health Organization (free) AND Hidden Hazards: An Exploration of Open Water Drowning and Risks for Children – Safe Kids Worldwide (free PDF)
Source: Global Health NOW Newsletter
“Each year they kill, on average, more lives in Australia than bushfires, floods, cyclones and sharks combined.
The global drowning prevention community is out to spread the word on identifying and escaping deadly rip currents with a public awareness campaign today. Check out a documentary and study guide focused on rip current science and survival strategies from National Geographic and Australia’s Rob Brander, a global expert in the field from UNSW Sydney”. (from Global Health NOW Newsletter)
Guideline: Management of Idiopathic Intracranial Hypertension
29 Jun, 2018 | 02:06h | UTC
Thu, June 28 – 10 Stories of The Day!
28 Jun, 2018 | 00:02h | UTC
Commentaries: Heat-stable drug could save thousands from post-childbirth bleeding: WHO – Reuters (free) AND Saving Moms’ Lives During Childbirth Just Got Easier – NPR (free)
2 – Clinical Report: The Prenatal Visit – The American Academy of Pediatrics (free)
News Release: What to cover during prenatal visit: AAP clinical report offers guidance – AAP News (free)
Commentaries: Urge expectant parents to have prenatal pediatrician visit – Pediatric News (free) AND AAP updates recommendations for prenatal visits – Healio (free registration required)
3 – Guideline Synopsis: Management of Ventricular Arrhythmias and Sudden Cardiac Death Risk Associated With Cardiac Channelopathies – JAMA Cardiology (free for a limited period)
Original Guideline: 2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death – Circulation (free PDF)
4 – Sex‐Specific Associations Between Alcohol Consumption and Incidence of Hypertension: A Systematic Review and Meta‐Analysis of Cohort Studies – Journal of the American Heart Association (free for a limited period)
Related Study: Effects of Repeated Binge Drinking on Blood Pressure Levels and Other Cardiovascular Health Metrics in Young Adults: National Health and Nutrition Examination Survey, 2011‐2014 – Journal of the American Heart Association (free for a limited period)
Editorial: Alcohol Consumption, Hypertension, and Cardiovascular Health Across the Life Course: There Is No Such Thing as a One‐Size‐Fits‐All Approach (free)
Commentaries: Young binge drinkers may have higher heart risks – AHA Newsroom (free) AND Alcohol Intake Tied to Elevated Blood Pressure – NEJM Physician’s First Watch (free) AND Binge drinking may increase heart risks for younger people – UPI (free)
5 – Dietary Recommendations for Adults With Psoriasis or Psoriatic Arthritis From the Medical Board of the National Psoriasis Foundation: A Systematic Review – JAMA Dermatology (link to abstract- $ for full-text)
Commentaries: What is the Role of Diet in Psoriasis and Psoriatic Arthritis? – MedicalResearch.com (free) AND Dietary Changes Can Lessen Severity of Psoriatic Disease – Medscape (free registration required) AND Can Diet Help in Psoriasis? – MedPage Today (free registration required) AND NPF Dietary Recommendations for Psoriatic Disease – RheumNow (free)
6 – Perspective: FDA Repays Industry by Rushing Risky Drugs to Market – ProPublica (free)
Commentary: Pediatric pancreatitis: nutritional care recommendations from ESPGHAN-NASPGHAN – Univadis (free registration required)
Related Guideline: Recommendations on Disease Management for Patients With Advanced Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer and Brain Metastases: ASCO Clinical Practice Guideline Update – Journal of Clinical Oncology (free)
10 – Association of Retinal Nerve Fiber Layer Thinning With Current and Future Cognitive Decline: A Study Using Optical Coherence Tomography – JAMA Neurology (free for a limited period)
Commentaries: Eye Sign of Dementia Risk? Thinning of Retinal Nerve Fiber Layer – MedicalResearch.com (free) AND Are the Eyes Windows to Early Dementia? – MedPage Today (free registration required)
“A thinner Retinal Nerve Fiber Layer is associated with worse cognitive function in individuals without a neurodegenerative disease as well as greater likelihood of future cognitive decline”.
Wed, June 27 – 10 Stories of The Day!
27 Jun, 2018 | 00:02h | UTC
Editorials: Screening for Osteoporosis (free) AND Osteoporosis Screening—2 Steps May Be Too Much for Women Younger Than 65 Years (free)
Author Interview: USPSTF Recommendation Statement: Screening for Osteoporosis to Prevent Fractures (free)
See also: USPSTF Final Recommendation Statement (free)
3 – Recurrent Glioblastoma Treated with Recombinant Poliovirus – New England Journal of Medicine (free for a limited period)
Editorial: Exploiting Viruses to Treat Diseases (free for a limited period)
Commentaries: Doctors Try Genetically Modified Poliovirus As Experimental Brain Cancer Treatment – NPR (free) AND Poliovirus therapy shows early promise in patients with aggressive brain cancer but questions linger – STAT (free)
4 – Closed-Loop Insulin Delivery for Glycemic Control in Noncritical Care – New England Journal of Medicine (free for a limited period)
Commentaries: Improved Glycemic Control With Closed-Loop Insulin Delivery System – Endocrinology Advisor (free) AND Closed-Loop Diabetes Systems (Artificial Pancreas) Can Be Used For Inpatient Care – MedicalResearch.com (free)
5 – Different defibrillation strategies in survivors after out-of-hospital cardiac arrest – Heart (free)
Commentary: Onsite defibrillators helping to increase cardiac arrest survival – Reuters (free)
Related Studies: Impact of Bystander Automated External Defibrillator Use on Outcomes (free study and commentaries) AND Use of public defibrillators linked to out-of-hospital cardiac arrest survival (link to abstract and commentaries) AND Bystander Efforts and 1-Year Outcomes in Out-of-Hospital Cardiac Arrest (link to abstract and commentaries)
6 – Deprescribing Proton Pump Inhibitors – Therapeutics Initiative (free)
Related guidelines: Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Deprescribing antihyperglycemic agents in older persons: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Deprescribing antipsychotics for behavioural and psychological symptoms of dementia and insomnia: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Deprescribing benzodiazepine receptor agonists – Canadian Family Physician (free)
Commentaries: Long-term weight loss of at least 20% helps improve outcomes in overweight, obese patients with knee osteoarthritis – ACP Internist (free) AND When it comes to weight loss in overweight and obese adults with knee osteoarthritis, more is better – Wiley, via ScienceDaily (free) AND More weight loss tied to less knee pain for obese people – Reuters (free) AND More Weight Loss Linked To Greater Decrease in Knee Arthritis Pain – MedicalResearch.com (free)
8 – The economic cost of inadequate sleep – Sleep (free)
Commentaries: Inadequate sleep could cost countries billions – Oxford University Press USA, via EurekAlert (free) AND Wake-up call: Sleepiness ‘epidemic’ costing global economies billions – The Sidney Morning Herald (free)
9 – Donepezil for dementia due to Alzheimer’s disease – Cochrane Library (free)
Summary: Donepezil for people with dementia due to Alzheimer’s disease – Cochrane Library (free)
10 – Percutaneous Ablation Versus Partial and Radical Nephrectomy for T1a Renal Cancer: A Population-Based Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Percutaneous ablation may be preferred to nephrectomy for selected patients with early-stage renal cancer – ACP Internist (free) AND New Findings Support Ablation for Small Renal Tumors – Renal & Urology News (free)
Related Meta-Analysis: Radiofrequency ablation versus partial nephrectomy for treatment of renal masses: A systematic review and meta-analysis – The Kaohsiung Journal of Medical Sciences (free) AND Radiofrequency Ablation Versus Partial Nephrectomy in Treating Small Renal Tumors: A Systematic Review and Meta-Analysis – Medicine (free)
“Percutaneous ablation for T1a renal cancer has similar 5-year survival rates to radical nephrectomy but with far fewer 30-day complications and less kidney failure (via @AnnalsofIM see Tweet)
ESMO Guideline: Diarrhea in Adult Cancer Patients
24 Jun, 2018 | 19:34h | UTCDiarrhoea in adult cancer patients: ESMO Clinical Practice Guidelines – Annals of Oncology (free)
Mon, June 25 – 10 Stories of The Day!
25 Jun, 2018 | 00:38h | UTC
1 – Diarrhoea in adult cancer patients: ESMO Clinical Practice Guidelines – Annals of Oncology (free)
Summary: Interventions for babies from birth to one month of life for preventing cerebral palsy: an overview of Cochrane Systematic Reviews (free)
3 – Prophylactic abdominal drainage for pancreatic surgery – Cochrane Library (free)
Summary: Drain use after pancreatic surgery – Cochrane Library (free)
See also: Highlights (free PDF) AND FAQs (free PDF) AND Infographic (free PDF)
5 – Perspective: Breathing Tubes Fail to Save Many Older Patients – The New York Times (10 articles per month are free)
“One-third of patients over age 65 die in the hospital after they are put on ventilators. Doctors are beginning to wonder if the procedure should be used so often”.
Editorial: Interprofessional Evidence-Based Practice Competencies: Equalizing the Playing Field (free)
“68 core competencies for evidence-based practice for health professionals, developed using systematic review & Delphi consensus process” (via @hildabast see Tweet)
7 – Association of Initiation of Basal Insulin Analogs vs Neutral Protamine Hagedorn Insulin With Hypoglycemia-Related Emergency Department Visits or Hospital Admissions and With Glycemic Control in Patients With Type 2 Diabetes – JAMA (free for a limited period)
Editorial: Revisiting NPH Insulin for Type 2 Diabetes: Is a Step Back the Path Forward? (free for a limited period)
Clinical Review Audio: Health Care Spending Gone Wild: Using Expensive Insulin Analogs With Few Clinical Advantages (free)
“Long-acting insulin analogs not associated with reduced hypoglycemia-related ED visits or hospital admissions when compared with NPH insulin, despite costing 5-10x as much” (via @jsross119 see Tweet)
8 – Long-term albumin administration in decompensated cirrhosis (ANSWER): an open-label randomised trial – The Lancet (link to abstract – $ for full-text)
Commentary: Spotlight on albumin in cirrhosis – ACP Gastroenterology (free)
9 – Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Commentary: BICAR-ICU – The Bottom Line (free)
“This study will reassure clinicians that already use sodium bicarbonate for correcting metabolic acidaemia, that this may delay and/or reduce the requirement for RRT. Equally, for those that opt to avoid sodium bicarbonate, there is no compelling evidence to change practice” (from The Bottom Line)
Commentaries: Outcomes in Patients With Angina but Without Obstructive CAD – American College of Cardiology (free)
Tue, June 26 – 10 Stories of The Day!
26 Jun, 2018 | 00:09h | UTC
1 – Association of a Bundled Hospital-at-Home and 30-Day Postacute Transitional Care Program With Clinical Outcomes and Patient Experiences – JAMA Internal Medicine (free for a limited period)
Editorial: Hospital-at-Home Care Programs—Is the Hospital of the Future at Home? (free for a limited period)
Author Interview: Association of a Bundled Hospital-at-Home Program With Clinical Outcomes and Patient Experiences (free)
Commentaries: Hospital-at-Home Bundled Program Associated With Better Clinical Outcomes, Patient Experiences – AJMC (free) AND Clinical outcomes and patient experiences vastly improved with hospital at home – The Mont Sinai Hospital, via MedicalXpress (free) AND Hospital-at-Home Care a Potential Alternative to Inpatient Care – Physician’s First Watch (free)
Related: New Document for Patients: Advanced Health Directive for Dementia (free document and commentaries) AND Alzheimer’s? Your Paperwork May Not Be in Order – The New York Times (10 articles per month are free)
3 – Errors in estimating usual sodium intake by the Kawasaki formula alter its relationship with mortality: implications for public health – International Journal of Epidemiology (link to abstract – $ for full-text)
Commentaries: Accurate measurements of sodium intake confirm relationship with mortality – ScienceDaily (free) AND Better estimate of intake more firmly links salt, death – UPI (free)
Related Report: Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks – Agency for Healthcare Research and Quality (free)
4 – Saline irrigation for allergic rhinitis – Cochrane Library (free)
Summary: Nasal saline for allergic rhinitis – Cochrane Library (free)
5 – Richard Lehman’s journal review, 25 June 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Related Guidelines: Difficult Airway Society 2015 guidelines for management of unanticipated difficult intubation in adults – British Journal of Anaesthesia (free) AND Practice Guidelines for Management of the Difficult Airway: An Updated Report by the American Society of Anesthesiologists Task Force on Management of the Difficult Airway – Anesthesiology (free)
Source: Critical Care Reviews Newsletter
7 – Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Robotic, Open Cystectomy Offer Comparable Bladder Cancer Outcomes – Renal & Urology News (free) AND RAZOR study: No differences in robotic vs open surgery for bladder cancer – Coloproctology News (free) AND Robotic surgery is no better than traditional surgery, bladder cancer study finds – The Washington Post (free)
8 – A Randomized Controlled Trial of Parent-Child Psychotherapy Targeting Emotion Development for Early Childhood Depression – The American Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Parent-Child Psychotherapy Leads to Improvements in Young Children With Depression – Psychiatric News Alert (free) AND Psychotherapeutic intervention shows promise for treating depression in preschool-aged children – NIH News Releases (free) AND Parent-child therapy helps young children with depression – Washington University School of Medicine, via ScienceDaily (free)
Related Study: Talking therapy given by parents shows promise for childhood anxiety disorders (free research, editorial and commentaries)
9 – Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration – JAMA (link to abstract – $ for full-text)
Commentaries: Oxygen for preterm infants, what dose of this toxic drug is the right dose? #NeoEBM – Neonatal Research (free) AND Lower and higher oxygen saturation targets result in equal but contrasting outcomes for extremely preterm infants – 2 Minute Medicine (free)
10 – Association Between Portable Music Player Use and Hearing Loss Among Children of School Age in the Netherlands – JAMA Otolaryngology-Head & Neck Surgery (link to abstract – $ for full-text)
Commentaries: Portable music players tied to hearing loss in kids – Reuters (free) AND Portable Music Player Use Linked to Hearing Loss in Children – MPR (free)
Consensus Statement: Core Competencies in Evidence-Based Practice for Health Professionals
24 Jun, 2018 | 19:29h | UTCEditorial: Interprofessional Evidence-Based Practice Competencies: Equalizing the Playing Field (free)
“68 core competencies for evidence-based practice for health professionals, developed using systematic review & Delphi consensus process” (via @hildabast see Tweet)
Systematic Reviews: Neonatal Interventions for Preventing Cerebral Palsy
24 Jun, 2018 | 19:33h | UTCSummary: Interventions for babies from birth to one month of life for preventing cerebral palsy: an overview of Cochrane Systematic Reviews (free)
Scientific Statement: Educational Strategies to Improve Outcomes From Cardiac Arrest
24 Jun, 2018 | 19:31h | UTCSee also: Highlights (free PDF) AND FAQs (free PDF) AND Infographic (free PDF)
Systematic Review: Prophylactic Abdominal Drainage for Pancreatic Surgery
24 Jun, 2018 | 19:32h | UTCProphylactic abdominal drainage for pancreatic surgery – Cochrane Library (free)
Summary: Drain use after pancreatic surgery – Cochrane Library (free)


